Cutting-edge biological and bioinformatics research seeks a systems perspective through the analysis of multiple types of high-throughput and other experimental data for the same sample. systems-level analysis require...
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ISBN:
(纸本)0769523447
Cutting-edge biological and bioinformatics research seeks a systems perspective through the analysis of multiple types of high-throughput and other experimental data for the same sample. systems-level analysis requires the integration and fusion of such data, typically through advanced statistics and mathematics. Visualization is a complementary computational approach that supports integration and analysis of complex data or its derivatives. We present a bioinformatics visualization prototype, Juxter, which depicts categorical information derived from or assigned to these diverse data for the purpose of comparing patterns across categorizations. The visualization allows users to easily, discern correlated and anomalous patterns in the data. These patterns, which might not be detected automatically by, algorithms, may, reveal valuable information leading to insight and discovery. We describe the visualization and interaction capabilities and demonstrate its utility in a new field, metagenomics, which combines molecular biology and genetics to identify and characterize genetic material from multi-species microbial samples.
Functionally related genes co-evolve, probably due to the strong selection pressure in evolution. Thus we expect that they are present in multiple genomes. Physical proximity among genes, known as gene team, is a very...
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Prediction of a transcription start site (TSS) is one of the many active research areas in bioinformatics. The main purpose of this paper is to study the ability of linear classifiers for predicting a TSS. Also we hav...
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Prediction of a promoter is one of the many active areas of bioinformatics. The outcome of a promoter detection algorithm is directly or indirectly influenced by the success of identifying the location of a TATA box i...
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