程序化细胞死亡分子5(PDCD5,Programmed Cell Death 5,原名TFAR19)是北京大学医学部人类疾病基因研究中心发现的凋亡表达上调蛋白,在人体50多种组织中广泛表达,是一种进化保守的蛋白。功能研究表明,它是参与细胞凋亡和抑制细胞生长的重...
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程序化细胞死亡分子5(PDCD5,Programmed Cell Death 5,原名TFAR19)是北京大学医学部人类疾病基因研究中心发现的凋亡表达上调蛋白,在人体50多种组织中广泛表达,是一种进化保守的蛋白。功能研究表明,它是参与细胞凋亡和抑制细胞生长的重要调控分子。近来的结果显示,PDCD5在非凋亡的paraptosis 样程序化细胞死亡过程中也发挥正向促进作
Hepatocellular carcinoma (HCC), or liver cancer is the fifth most common cancer in the world and results in nearly one million deaths per year. Wide geographic variability, it occurs most frequently in Asia and sub-Sa...
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Hepatocellular carcinoma (HCC), or liver cancer is the fifth most common cancer in the world and results in nearly one million deaths per year. Wide geographic variability, it occurs most frequently in Asia and sub-Saharan Africa, but it is now become more common in the west countries. HCC has risen by 114% per
The development of sensitive and rapid analytical assay is an important task to conquer drug abuse problem and assure the effectiveness of treatment program. The lack of specificity and sensitivity of immunoassay limi...
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The development of sensitive and rapid analytical assay is an important task to conquer drug abuse problem and assure the effectiveness of treatment program. The lack of specificity and sensitivity of immunoassay limits its application. GC/MS is an excellent method provided
The quadrupole field in a digital ion trap (DIT) is created by applying between the trap electrodes a digital high voltage generated by switching electronic circuit. Being different from a conventional RF ion trap, DI...
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The quadrupole field in a digital ion trap (DIT) is created by applying between the trap electrodes a digital high voltage generated by switching electronic circuit. Being different from a conventional RF ion trap, DIT uses frequency jump and frequency scans in order to manipulate ions and perform mass analysis.
Multi-dimensional mass spectrometry (MD-MS) is a newly emerging technology in mass spectrometry, which is analogous to multi-dimensional nuclear magnetic resonance spectroscopy. Each series of ramped changes in one of...
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Multi-dimensional mass spectrometry (MD-MS) is a newly emerging technology in mass spectrometry, which is analogous to multi-dimensional nuclear magnetic resonance spectroscopy. Each series of ramped changes in one of the instrumental conditions (i. e. , one variable) facilitate the generation of a dimen-
A typical protein is born at translation, matures through post-translational processing events, such as partial proteolysis, alternates between active and resting states through the intervention of regulatory ligands ...
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A typical protein is born at translation, matures through post-translational processing events, such as partial proteolysis, alternates between active and resting states through the intervention of regulatory ligands or covalent modifications, ages through oxidation, deamid-ation, etc. , and expires when targeted for deg-
Non-covalent interactions between biomol-ecules play a central role in many molecular recognition processes. Examples include enzyme-substrate, protein-ligand, protein-protein and antibody-antigen interactions. Non-co...
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Non-covalent interactions between biomol-ecules play a central role in many molecular recognition processes. Examples include enzyme-substrate, protein-ligand, protein-protein and antibody-antigen interactions. Non-covalent interactions between the folded polypeptide
Mass spectrometry is a powerful technique that is used in a wide range of professions for both routine and research purposes. It also has an important role in the U. S. criminal justice system. The Drug Enforcement Ad...
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Mass spectrometry is a powerful technique that is used in a wide range of professions for both routine and research purposes. It also has an important role in the U. S. criminal justice system. The Drug Enforcement Administration (DEA) is a component of the United States Department of Justice. It is headed by an Admin-
With the growing knowledge and progress in nanotechnology, interest has been developed to integrate nanosciences into present and new emerging technology. It is also important to have efficient tools to cope up with t...
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With the growing knowledge and progress in nanotechnology, interest has been developed to integrate nanosciences into present and new emerging technology. It is also important to have efficient tools to cope up with the growing needs of characterization of complex systems involving nano-materials. Thus, scientists are in search of
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