Bio-inspired nanomaterials are currently investigated as excellent candidates for gene/drug delivery systems and imaging probes,providing new opportunities in the management of cancer. We described novel approach for ...
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Bio-inspired nanomaterials are currently investigated as excellent candidates for gene/drug delivery systems and imaging probes,providing new opportunities in the management of cancer. We described novel approach for the construction of multifunctional peptide dendrimer-based nanosystems as MRI *** peptide dendrimers possessing highly controlled structures were used as
Purpose:With the rapid development of nanotechnology,there is a growing interest on the application of nano-materials in various fields such as photonics,catalysis,magnetics,and biotechnology including cosmetics,pharm...
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Purpose:With the rapid development of nanotechnology,there is a growing interest on the application of nano-materials in various fields such as photonics,catalysis,magnetics,and biotechnology including cosmetics,pharmaceutics,and medicines(1).Recently, there are a number of reports regarding the toxicity evaluation of inorganic ***,the knowledge on the
The article is to review the research process and application of amino acid fragments used as carrier in nanometer drug delivery *** poly-amino acid carrier is mainly applied as pH-sensitive carrier,micelles-forming c...
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The article is to review the research process and application of amino acid fragments used as carrier in nanometer drug delivery *** poly-amino acid carrier is mainly applied as pH-sensitive carrier,micelles-forming carrier and gene therapy carrier.
Mefformin hydrochloride resinates were prepared by bath method using a strongly acidic cation-exchange resin as the *** drug resinate's combination pattern was characterized by X-ray *** effects of the reaction te...
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Mefformin hydrochloride resinates were prepared by bath method using a strongly acidic cation-exchange resin as the *** drug resinate's combination pattern was characterized by X-ray *** effects of the reaction temperature and particle size of the ion-exchange resin on the process of ion exchange were investigated,the kinetics and thermodynamics were studied under different conditions.
NSAID are widely used *** recent years,plenty of evidence suggests that NSAID can act as neuroprotective agents,and has curative effect of *** their distribution in the brain are very ***,we choose ibuprofen as a mode...
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NSAID are widely used *** recent years,plenty of evidence suggests that NSAID can act as neuroprotective agents,and has curative effect of *** their distribution in the brain are very ***,we choose ibuprofen as a model drug,nutritional substance Vitamin C as the *** plan to synthesis a new prodrug,then study its ability for brain targeting.
The final purpose of this research is finding influencing factors of multiple agents loaded nanoparticles by study of dual agents loaded *** acid(OA) and Gentiopicroside(GEN) were found to be effective in treating hep...
The final purpose of this research is finding influencing factors of multiple agents loaded nanoparticles by study of dual agents loaded *** acid(OA) and Gentiopicroside(GEN) were found to be effective in treating hepatitis from different *** the poor water-solubility of OA and short half-life period of GEN,the bioavailabilities were not well.
One of the important characteristics of a nanoparticle is the charge on the *** understand the potential interactions between the charge of the nanocarriers and cells is of great importance for developing better and s...
One of the important characteristics of a nanoparticle is the charge on the *** understand the potential interactions between the charge of the nanocarriers and cells is of great importance for developing better and safer *** use a variety of charged liposomes as a nanoparticle model,as well as other cationic materials as controls to observe biological behavior of the treated cells.
One of the main challenges in the synthesis of targeted drug-carrier conjugates is the efficient coupling of drugs onto the carrier *** have developed a novel and straightforward strategy for drug conjugation that emp...
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One of the main challenges in the synthesis of targeted drug-carrier conjugates is the efficient coupling of drugs onto the carrier *** have developed a novel and straightforward strategy for drug conjugation that employs platinum coordination *** applied linker system reacts to aromatic nitrogen atoms,a functional group that is present in many drug *** renders the developed approach compatible with a wide range of drug
siRNA therapy is extremely promising for the treatment of many life-threatening ***,the lack of a means to deliver these therapeutics in a safe and efficient way has limited their application. Accordingly,in this rese...
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siRNA therapy is extremely promising for the treatment of many life-threatening ***,the lack of a means to deliver these therapeutics in a safe and efficient way has limited their application. Accordingly,in this research,a safe and efficient siRNA delivery system has been developed using physiologically occurring anionic ***,systematic characterization of this delivery system has been conducted to understand the formulation characteristics(including morphology) that affect its bioactivity.
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