Biological macro molecular drugs such as polypeptides,proteins,nucleic acid,etc.,are generally administered by injection due to their poor stability,short half-life,not easy to pass through the biological membrane and...
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Biological macro molecular drugs such as polypeptides,proteins,nucleic acid,etc.,are generally administered by injection due to their poor stability,short half-life,not easy to pass through the biological membrane and low oral ***,as long term
Objective:The aim of this study is to provide a theoretical method on the basis of Hansen solubility parameters(HSPs)for screening drug-polymer pairs in the early stage of grafted polymeric micelles ***:The compatibil...
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Objective:The aim of this study is to provide a theoretical method on the basis of Hansen solubility parameters(HSPs)for screening drug-polymer pairs in the early stage of grafted polymeric micelles ***:The compatibility of drug and polymer was evaluated by HSPs with the
Vitamin K1 is one of fat-soluble vitamins which is mostly required for blood coagulation It acts as a cofactor in the synthesis of active blood-clotting factors n,Ⅶ,DC,X,protein C and so on There are many Vitamin Kl ...
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Vitamin K1 is one of fat-soluble vitamins which is mostly required for blood coagulation It acts as a cofactor in the synthesis of active blood-clotting factors n,Ⅶ,DC,X,protein C and so on There are many Vitamin Kl products that have been approved for clinical use to *** the application of nanotechnology to drug
Computational pharmaceutics integrates computer modelling technique and experimental approaches to investigate molecular mechanism of pharmaceutical formulations for better medicines.[1]Two examples were discussed,inc...
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Computational pharmaceutics integrates computer modelling technique and experimental approaches to investigate molecular mechanism of pharmaceutical formulations for better medicines.[1]Two examples were discussed,including solid dispersion and siRNA *** solid dispersion,the molecular structure of solid
Hot melt extrusion(HME)is a powerful technology to enhance the solubility and bioavailability of poorly water-soluble drugs by producing amorphous/crystalline solid dispersions or *** the number of articles and patent...
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Hot melt extrusion(HME)is a powerful technology to enhance the solubility and bioavailability of poorly water-soluble drugs by producing amorphous/crystalline solid dispersions or *** the number of articles and patents about HME increased dramatically in the past twenty years,there are very few commercial products by *** main
Understanding the performance of engineered micro/nano materials in a biological context is an important issue for guiding their biomedical *** two-dimensional nanomaterial graphene oxide(GO)has attracted explosive in...
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Understanding the performance of engineered micro/nano materials in a biological context is an important issue for guiding their biomedical *** two-dimensional nanomaterial graphene oxide(GO)has attracted explosive interests in various ***,its performance in biological environments is still largely
Crystal engineering is the study of intermolecular interactions in the context of crystal packing,and the utilization of such study to design new solids with desirable physicochemical *** recent years,crystal engineer...
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Crystal engineering is the study of intermolecular interactions in the context of crystal packing,and the utilization of such study to design new solids with desirable physicochemical *** recent years,crystal engineering has played an important role in the area of pharmaceutical industry and academia by means of
Chemotherapy is widely used to treat *** is nonetheless accompanied by terrible side-effects resulting from the ubiquitous exposure in the body to cytotoxic chemicals that are intended to eliminate malignant *** the s...
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Chemotherapy is widely used to treat *** is nonetheless accompanied by terrible side-effects resulting from the ubiquitous exposure in the body to cytotoxic chemicals that are intended to eliminate malignant *** the systemic toxicities is the universal utilization of carrier chemicals to deliver the c he mo therapeutic drugs.
Nucleic acid-based methods for controlling gene expression have had a considerable impact on research involving gene pathways and *** addition,gene therapies are potentially powerful candidates for clinical treatments...
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Nucleic acid-based methods for controlling gene expression have had a considerable impact on research involving gene pathways and *** addition,gene therapies are potentially powerful candidates for clinical treatments of various ailments,including cancer and HIV/***,their development into viable therapeutic
Objective:Owning to its excellent properties such as biocompatibility,biodegradability,and non-toxicity,calcium phosphate holds great potential in pharmaceutical *** this study,we prepared calcium phosphate/carboxymet...
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Objective:Owning to its excellent properties such as biocompatibility,biodegradability,and non-toxicity,calcium phosphate holds great potential in pharmaceutical *** this study,we prepared calcium phosphate/carboxymethylcellulose(CaP/CMC)hybrids by the biomimetic mineralization and
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