Glioma is the most abundant of all primary central nervous system(CNS)*** to the severity of the disease,ghoma is graded fromⅠ(benign)toⅣ(highly mahgnant).And the fow-grade tumors usually evolved into a high-grade g...
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Glioma is the most abundant of all primary central nervous system(CNS)*** to the severity of the disease,ghoma is graded fromⅠ(benign)toⅣ(highly mahgnant).And the fow-grade tumors usually evolved into a high-grade glioblastoma ***,irrespective of their grading,primary ghoma
We took advantage of the poor solubihty of cisplatin to prepare a nano-precipitate which is stabilized with a single lipid bilayer *** resulting nanopartkles,containing 80-90%cisplatin by mass,are further functionaliz...
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We took advantage of the poor solubihty of cisplatin to prepare a nano-precipitate which is stabilized with a single lipid bilayer *** resulting nanopartkles,containing 80-90%cisplatin by mass,are further functionalized with anisamide for sigma receptor *** cisplatin releases cisplatin inside the cells over-expressing the *** associated fibroblasts(TAFs)are the major cells
The changing landscape both in the pharmaceutical industry and in academia has led to an increased need to better prepare graduate students for careers in industry,academia,and *** a 2013 AAPS retreat focusing on the ...
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The changing landscape both in the pharmaceutical industry and in academia has led to an increased need to better prepare graduate students for careers in industry,academia,and *** a 2013 AAPS retreat focusing on the needs of our graduates,certainly a strong scientific knowledge is deemed important,but also "soft
In the present study,a specific targeting nucleic acid delivery system was rationally designed,which comprised quaternary components(Q-complexes)as a multifunctionally cationic peptide formed of polyarginine conjugati...
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In the present study,a specific targeting nucleic acid delivery system was rationally designed,which comprised quaternary components(Q-complexes)as a multifunctionally cationic peptide formed of polyarginine conjugating with Cell-penetrating peptides with targeting capabilities,cationic liposome self-assembled
INTRODUCTION:Immunotherapy is to generate a robust immune response that confers long-lasting protection against tumor invasion,metastasis or *** T cell immunity using antigen-adjuvant combinations has been achieved by...
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INTRODUCTION:Immunotherapy is to generate a robust immune response that confers long-lasting protection against tumor invasion,metastasis or *** T cell immunity using antigen-adjuvant combinations has been achieved by encapsulating them in *** reduce systemic dispersion and promote DCs
In drug delivery systems,protein-based capsules have attracted attention among various hollow vehicles due to the good biocompatibihty and distinct mechanical properties of natural proteins.[l,2]In this study,silk fib...
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In drug delivery systems,protein-based capsules have attracted attention among various hollow vehicles due to the good biocompatibihty and distinct mechanical properties of natural proteins.[l,2]In this study,silk fibroin nanocapsules were
RNA interference(RNAi)is emerging as one of promising strategies for tumor therapy,especially for inhibiting tumor ***,an efficient and safety non-virus delivery system for siRNA is still one of the major *** this work,
RNA interference(RNAi)is emerging as one of promising strategies for tumor therapy,especially for inhibiting tumor ***,an efficient and safety non-virus delivery system for siRNA is still one of the major *** this work,
Transdermal delivery of biomolecules,including proteins,nucleic acids and vaccines,using dissolving microneedles(MNs)presents a promising alternative *** study evaluated the feasibility of transdermal exenatide(EXT)de...
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Transdermal delivery of biomolecules,including proteins,nucleic acids and vaccines,using dissolving microneedles(MNs)presents a promising alternative *** study evaluated the feasibility of transdermal exenatide(EXT)delivery using MNs patches for type 2 diabetes mellitus *** casting method and low-molecular-weight sodium hyaluronate(HA)
Poly(DL-lacticco-glycolic acid)(PLGA)microspheres were widely prepared by many methods,such as solvent evaporation,solvent extraction and co-solvent ***,very limited studies have compared the differences between the p...
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Poly(DL-lacticco-glycolic acid)(PLGA)microspheres were widely prepared by many methods,such as solvent evaporation,solvent extraction and co-solvent ***,very limited studies have compared the differences between the properties of microspheres fabricated by these *** is partly because that broad size
In nature,biological systems synthesize all kinds of materials which possess hierarchical structures with controlled size,shape,ahgnment,and *** by this,scientists are very keen to develop synthetic strategies for mim...
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In nature,biological systems synthesize all kinds of materials which possess hierarchical structures with controlled size,shape,ahgnment,and *** by this,scientists are very keen to develop synthetic strategies for mimicking these natural processes,like *** recent years,biogenic calcium carbonate has become a promising drug deHvery system due to its outstanding safety,pH
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