Background:Osteoporotic vertebral compression fracture(OVCF) is a common disease in old people,especially for aged *** kyphoplasty(PKP) is accepted as an effective therapy for ***,it is still controversial whether uni...
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Background:Osteoporotic vertebral compression fracture(OVCF) is a common disease in old people,especially for aged *** kyphoplasty(PKP) is accepted as an effective therapy for ***,it is still controversial whether unilateral approach or bilateral approach is *** now there is no systematic review focus on this ***:We searched the Cochrane Central Register of Controlled Trials(The Cochrane Library 2013,Issue 1),PubMed MEDLINE,EMBASE,ISI web of knowledge MEDLINE(January 1980 to June 2013) and reference lists of eligible *** evidence quality levels and recommendations were assessed using the GRADE ***:Seven studies encompassing 310 patients met the inclusion *** meta-analysis was performed according to the study *** were no significant differences between the two procedures in short- and long-term VAS,short- and long-term ODI,cement leakage rate,adjacent-level fractures rate,and kyphosis angles reduction for either subgroup *** was a significant difference in operation time between the two procedures favoring the unilateral *** overall GRADE system evidence quality was very low,only with a moderate to high evidence of operation time result,which lowers our confidence in ***:Unilateral PKP and bilateral PKP are both safe and effective surgical procedures for treating *** significant clinical differences were found between *** less operation time,less cost and less radiation exposure,we make a bold recommendation for unilateral PKP over bilateral *** to the poor quality of the evidence,high quality RCTs are required.
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