Three photoreceptors exist in the mammalian retina,rods,cones and ipRGCs(known as intrinsically photosensitiveretinal ganglion cells).ipRGCs function both as ganglion cells and also contain the photopigrnent *** ipRGC...
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Three photoreceptors exist in the mammalian retina,rods,cones and ipRGCs(known as intrinsically photosensitiveretinal ganglion cells).ipRGCs function both as ganglion cells and also contain the photopigrnent *** ipRGCs to detect light intrinsically through the melanopsin phototransduction pathway and by incorporatingrod/cone input through the classical retinal *** a decade of intense research,the relative contribution ofrods,cones and melanopsin
Zebrafish are an excellent model system in which to study the fundamental events of vertebrate *** contrast to mammals,large numbers of fertilized eggs develop outside of the *** embryos are also highly transparent,al...
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Zebrafish are an excellent model system in which to study the fundamental events of vertebrate *** contrast to mammals,large numbers of fertilized eggs develop outside of the *** embryos are also highly transparent,allowing imaging strategies to be readily *** such,zebrafish also represent a useful tool to study the development of the circadian clock.
The zebrafish(Daniorerio)displays robust daily changes in physiology and *** retroviral insertional mutagenesis,TALEN or CRISPR-Cas9,we have generated a library of zebrafish *** we report characterization of zebrafish...
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The zebrafish(Daniorerio)displays robust daily changes in physiology and *** retroviral insertional mutagenesis,TALEN or CRISPR-Cas9,we have generated a library of zebrafish *** we report characterization of zebrafishperlb,per2,timeless and rev-erbα*** assays showed that under light/dark(LD)condition,both perlb andrev-erbαmutant larvae display significantly elevated locomotor activity amplitudecompared with their wild-type
Sleep is ahighly conserved fundamentallife *** disorders are prevalent in general population and are associatedwith significant medical and social ***,sleep remains one of the least understood phenomena in *** behavio...
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Sleep is ahighly conserved fundamentallife *** disorders are prevalent in general population and are associatedwith significant medical and social ***,sleep remains one of the least understood phenomena in *** behavior,also considered as sleep/wake behavior,is regulated by a core transcription/translation feedback loop.A DNA polymorphism in the human PER3gene was recently shown to be associated with sleep disorder such as reduced
Cell-autonomous circadianclocks generate and maintain daily oscillations in various types oforganssuch as the brain,theliver and the ovary with a period of approximately24 *** most organs,thetestis remains a mystery w...
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Cell-autonomous circadianclocks generate and maintain daily oscillations in various types oforganssuch as the brain,theliver and the ovary with a period of approximately24 *** most organs,thetestis remains a mystery without clearly understandingof its clock activity and relevantclock-ddven physiology,asprevious studies in many species including rodents and zebrafish indicatednon-oscillatory
Objective:To observe the role of electro-acupuncture in regulating the circadian rhythm of the melatonin and its receptor,discuss the mechanism of electro-acupuncture in regulating the circadian rhythm of insomnia in ...
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Objective:To observe the role of electro-acupuncture in regulating the circadian rhythm of the melatonin and its receptor,discuss the mechanism of electro-acupuncture in regulating the circadian rhythm of insomnia in order to further provide a theoretical basis for treatment of insomnia by ***:168 clean SD male rats,with weight reaching 180±*** were randomly divided into control group(n=42),model group(n=42),acupuncture
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