目的 Tyrosine kinase inhibitors(TKIs)targeting the epidermal growth factor receptor(EGFR)have shown promising clinicalefficacy in non-squamous non-small cell lung cancer(NSCLC);however,resistance is frequently observe...
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目的 Tyrosine kinase inhibitors(TKIs)targeting the epidermal growth factor receptor(EGFR)have shown promising clinicalefficacy in non-squamous non-small cell lung cancer(NSCLC);however,resistance is frequently observed in malignant cells,operating through a mechanism that remains largely *** research is to study the molecular mechanism of TOPK inEGFR-TKI resistance.
目的 The mortality of acute respiratory distress syndrome(ARDS)is dramatically high and there is no proven pharmacologicintervention *** ventilation is one of the most important auxiliary ***,it may result in oxidativ...
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目的 The mortality of acute respiratory distress syndrome(ARDS)is dramatically high and there is no proven pharmacologicintervention *** ventilation is one of the most important auxiliary ***,it may result in oxidativestress and lead to ventilation induced lung injury(VILI)and lung ***,we hypothesized that the use of antioxidantmay ameliorate VILI and ARDS-associated lung fibrosis.
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