目的 To examined the potential of the microRNA response elements(MREs)-containing influenza A virus as a live attenuated vaccine by immunizing mice.方法 In this study,miR-let-7b target sequences were inserted into the...
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目的 To examined the potential of the microRNA response elements(MREs)-containing influenza A virus as a live attenuated vaccine by immunizing mice.方法 In this study,miR-let-7b target sequences were inserted into the H1N1 genome to engineer a recombinant virus - *** BALB/c mice were vaccinated intranasally with the miRT-H1N1 and challenged with a lethal dose of homologous virus.
目的 Asthma is a common chronic respiratory disease characterized by airway inflammation,airway hyperresponsiveness and mucus *** oxidative stress plays important role in pathogenesis and development of *** is a poten...
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目的 Asthma is a common chronic respiratory disease characterized by airway inflammation,airway hyperresponsiveness and mucus *** oxidative stress plays important role in pathogenesis and development of *** is a potent oxidant,which has been proved by various studies to have vicious effects on respiratory system of both human and ***,how ozone affects the pathophysiologic characteristics of the murine model of asthma with culminated allergic airway inflammation is still unknown.
目的 Pulmonary hypertension (PH) is an important complication of interstitial lung disease (ILD).The aim of the present study was to investigate characteristics and prognosis of ILD associated PH in China.方法 Consecu...
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目的 Pulmonary hypertension (PH) is an important complication of interstitial lung disease (ILD).The aim of the present study was to investigate characteristics and prognosis of ILD associated PH in China.方法 Consecutive patients with ILD associated PH in Shanghai Pulmonary Hospital,which was confirmed by right-sided heart catheterization,were included in the *** at baseline and during follow-up,as well as survival,were analyzed.
目的 Achromobacter xylosoxidans has been reported in many ***,hospital-acquired pneumonia(HAP)due to this organism in elderly patients in China remains rare.方法 HAP due to Achromobacter xylosoxidans identified at our...
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目的 Achromobacter xylosoxidans has been reported in many ***,hospital-acquired pneumonia(HAP)due to this organism in elderly patients in China remains rare.方法 HAP due to Achromobacter xylosoxidans identified at our hospital from January 2008 to October 2011 was *** detailed manifestations were collected.
目的 Many studies have investigated the efficacy of amrubicin as first-line treatment for extensive-disease small cell lung cancer(ED-SCLC).This is a meta-analysis to combined the available research.方法 Electronic da...
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目的 Many studies have investigated the efficacy of amrubicin as first-line treatment for extensive-disease small cell lung cancer(ED-SCLC).This is a meta-analysis to combined the available research.方法 Electronic databases were searched for relevant studies and five were eligible in this meta ***-comparative binarydata were meta-analyzed with the random-model generic inverse variance method.
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