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检索条件"任意字段=2016中华医学会呼吸病学年会暨第十七次全国呼吸病学学术会议"

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Effect of Wnt/β-catenin and NF-κB Signaling Pathways on Mucus Secretion with Hypertonicity in16HBE Cells

Effect of Wnt/β-catenin and NF-κB Signaling Pathways on Mu...

引用

2016中华医学会呼吸病学年会暨第十七次全国呼吸病学学术会议

作者： Liu Xiaoyan Li Jianqiang Zhao Hui Liu Tanzhen The Second Hospital Affiliated to Shanxi Medical University

目的 This study aimed at identifying the molecular mechanisms and effects of hypertonicity on mucin5AC(MUC5AC)expressionin airway epithelial cells.方法 Immortalized human bronchial epithelial(16HBE)cells were cultured in 600 mOsm/L hypertonic medium for different timesin *** of MUC5AC and β-catenin,Cyclin D1,NF-κB p65 were detected by enzyme linked immunosorbent assay(ELISA),reverse transcription(RT)-PCR and western blotting *** transfection of β-catenin siRNA in 16HBE cells,the levels of β-catenin,Cyclin D1,NF-κB p65 and MUC5AC protein were detected.

关键词： MUC5AC hypertonicity Wnt/β-catenin NF-κB p65

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The study of dosimetry and clinical quality comparison between IMRT and VMAT in irradiation for peripheral lung cancer and central lung cancer

The study of dosimetry and clinical quality comparison betwe...

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2016中华医学会呼吸病学年会暨第十七次全国呼吸病学学术会议

作者： JuanRen First hospital Affiliated to Xi'an Jiao Tong University

目的 This study compared IMRT and VMAT plans in peripheral and central lung cancer,especially in cases of PTV encompassing and not encompassing mediastinum. 方法 12 patients were randomly *** plans and VMAT plans were compared.结果 In peripheral lung cancer,IMRT showed better dose conformity and ***/PA/2PA-VMAT.2PA-VMAT showed better sparing of spinalcord,V5,V10 of lung-all and lung-contralateral than IMRT/PA/SA-VMAT,While IMRT showed better heart and lung-ipsilateral sparing than SA/PA/2PA-VMAT;In case of PTV not encompassing mediastinum in central lung cancer,2PA-VMAT showed better conformity and homogeneity than IMRT/PA/SA-VMAT,.

关键词： IMRT VMAT Dosimetry lung cancer

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Extensive recommendation of the detection of EGFR mutations in blood needs to be considered with caution:a systematic evaluation based on matched blood and tissue samples

Extensive recommendation of the detection of EGFR mutations ...

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2016中华医学会呼吸病学年会暨第十七次全国呼吸病学学术会议

作者： BiaoxueRong XiguangCai WenlongGao ZongfangLi ShuanyingYang Department of Respiratory Medicine Second Affiliated HospitalXi'an Jiaotong University 710004 Department of Respiratory Medicine Gansu Provincial Hospital 730000 Department of Statistics and Epidemiology Medical CollegeLanzhou University 730000 Department of Elderly Surgery Second Affiliated HospitalXi'an Jiaotong University 710004

目的 Blood has been used as a substitute for tumor tissue in detecting EGFR ***,not all results indicate a consistency of EGFR mutation status between the blood and *** conducted this systematic review to assess whether blood can be used as a reliable source for detecting EGFR mutations.方法 A systematic review was performed to evaluate the accuracy of EGFR mutation detection in matched blood and tissue *** up to December 2015 were searched for using the PubMed,Embase and Web of Science.

关键词： non-small cell lung cancer EGFR mutation liquid biopsy meta analysis

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CAP1is associated with metastasis of NSCLC especially in brain metastasis patients

CAP1is associated with metastasis of NSCLC especially in bra...

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2016中华医学会呼吸病学年会暨第十七次全国呼吸病学学术会议

作者： changhuiwang shuanshuanxie Shanghai Tenth's people hospital Tongji universityDepartment of respirologyshanghaiChina

目的 Lung cancer ranks first in both prevalence and mortality rates among all types of *** present study assessed thediagnostic and prognostic value of CAP1 for lung cancer.方法 Firstly,CAP1 were determined by PCR and western blot and IHC in 82 lung cancer *** group and non-BM groupwere treated and followed up by 4 *** regression and KM survival analysis were performed to correlateimmunoreactive CAP1 signal with cancer type and ***,to investigate the function of the CAP1 on the proliferation,migration and invasion of lung cancer cells in vitro and vivo of nude mice by knock down and over-expression ***,wemapped the S307D and S309D Phosphorylation sites of *** explore the relationship between CAP1 and Cofilin,Actin by IP,GST pull down assay,cell adhesion.

关键词： CAP1 Lung cancer metastasis Actin cytoskeleton

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OX40-OX40L interaction mediates basophils to prime Th2 responses in ovalbumin-induced allergic airway inflammation

OX40-OX40L interaction mediates basophils to prime Th2 respo...

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2016中华医学会呼吸病学年会暨第十七次全国呼吸病学学术会议

作者： caixiadi xiaolianglin yanjiezhang wenweizhong yufanyuan tongzhou junlingliu zhenweixia Ruijin Hospital affiliated with Shanghai Jiao Tong University School of Medicine Shanghai Children's Medical Center affiliated with ShanghaiJiao Tong University School of Medicine Shanghai Jiao Tong University School of Medicine

目的 To confirm the initiation role of basophils in the early phase of allergic airway inflammation,and further explore the potentmolecular mechanismy which basophils initiate Th2 responses,thus leading to allergic airway inflammation.方法 *** kinetics of numbers of basophils,dendritic cells(DCs)and Th2 cells in mediastinal lymph nodes(MLN)and the changeof molecular expression on basophils were observed in the early phase of asthma,respectively.

关键词： Asthma Th2responses OX40-OX40L interaction Basophils

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Autophagy is Induced by TGF-β1and Alleviates TGF-β1-Mediated Growth Inhibition in Human Non-Small Cell Lung Cancer Cells

Autophagy is Induced by TGF-β1and Alleviates TGF-β1-Mediat...

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2016中华医学会呼吸病学年会暨第十七次全国呼吸病学学术会议

作者： JianWang MeilingJin 复旦大学附属中山医院

目的 TGF-β1 is a cytokine with many biological *** the tumorigenesis,TGF-β1 has its two-side *** one handTGF-β1 promotes the apoptosis of tumor cells by inhibiting its cell *** the other hand,TGF-β1 helps the development andmetastasis of tumor cells by stimulating the epithelial-mesenchymal transition(EMT),tumor angiogenesis,and tumor ***-β1 can induce the autophagy of various tumor cells as well as normal *** autophagy is the highlyconservative “self-eaten” phenomenon,which plays a significant role in the process of TGF-β1 regulating hepatocellularcarcinoma ***,there is no research about the relationship between TGF-β1 and autophagy in lung ***,we aim to find whether TGF-β1 can induce autophagy in non-small lung cancer cells and to explore the association aboutbiological function between TGF-β1 and autophagy and its mechanism.

关键词： Autophagy TGF-β1 Growth Inhibition Lung Cancer

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ResponserateofacutepulmonaryvasoreactivitytestinginCTEPHpatientsissimilarwithIPAHpatients

ResponserateofacutepulmonaryvasoreactivitytestinginC...

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2016中华医学会呼吸病学年会暨第十七次全国呼吸病学学术会议

作者： Ji-FengLi Xiang-XiaZhang Tu-GuangKuang Yuan-HuaYang ChenWang DepartmentofRespiratoryandCriticalCareMedicine BeijingChao-YangHospitalCapitalMedicalUniv DepartmentofRespiratoryandCriticalCareMedicine BeijingChao-YangHospitalCapitalMedicalUniv DepartmentofRespiratoryDisease CapitalMedicalUniversityBeijingP.R.China.100069 China-Japan

目的 TocomparethepositiverateofAVTbetweenCTEPHpatientsandIPAH***toguidethechoiceofevaluationandstrategyoftreatmentforCTEPHpatients.方法 TheresponsetoAVTwasassessedin325consecutivepulmonaryhypertensionpatientswhichincluded58IPAHpatientsand209CTEPH***iloprost(20ug)wasusedforAVT.Adecreaseinthemeanpulmonaryarterypressurebyatleast10mmHgtoreachanabsolutevalueof40mmHgorlesswithoutadecreaseincardiacoutputisconsideredapositiveAVT.

关键词： acutepulmonaryvasoreactivitytesting IPAH CTEPH

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The effects of BCG vaccine on airway inflammation and remodeling in a rat model of asthma

The effects of BCG vaccine on airway inflammation and remode...

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2016中华医学会呼吸病学年会暨第十七次全国呼吸病学学术会议

作者： XinruiTian XinliTian RujieHuo QinChang GuopingZheng YanDu YanChen BoNiu The Second Hospital of Shanxi Medical University Chinese PLA General Hospital of Beijing Military Region Shanxi Medical University University of Sydney at Westmead Millennium Institute Capital Institute of Pediatrics

目的 To investigate the role of epithelial-mesenchymal transition (EMT) in airway inflammation and airway remodeling as well as the possible therapeutic mechanism of BCG for the treatment of asthma.方法 Wistar rats were sensitized and challenged by ovalbumin for 2 weeks or 8 *** was subcutaneously administered daily before every ovalbumin challenge or intracutaneously vaccinated on days 1,3,and 7 before sensitization to determine its therapeutic *** inflammation and airway remodeling changes were observed by HE stain under the light *** thicknesses of airway wall (WAt) and airway smooth muscle (WAm) were determined by morphometric analysis.

关键词： BCG vaccine Asthma Airway inflammation Airway remodeling TGF-β1 EMT

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DendriticcellsinduceTc1celldifferentiationbytheCD40/CD40Lpathwayinmiceafterexposuretocigarettesmoke

DendriticcellsinduceTc1celldifferentiationbytheCD40/...

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2016中华医学会呼吸病学年会暨第十七次全国呼吸病学学术会议

作者： Liang-JianKuang Ting-TingDeng QinWang Shi-LinQiu YiLiang Zhi-YiHe Jian-QuanZhang JingBai Mei-HuaLi Jin-MinDeng Guang-NanLiu Zhi-FengLiu Xiao-NingZhong thefirstaffilliatedhospitalofGuangxiMedicalUniversity

目的 ToexploretheroleoftheCD40/CD40Lpathwayindendriticcellregulation,Tc1celldifferentiationinmousemodelsofemphysemawasinducedbycigarettesmoke(CS)方法 C57BL/6JmiceandCD40-deficientmicewereexposedtosmokeorairforupto24***distributionanddifferentiationofTc1cellsinthesemicewere***dendriticcellsdistributionandtheircostimulatorymoleculesawerealsoinvestigated.

关键词： Emphysema CD40 Tc1cell dendriticcell pathway

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APreliminaryComparisonStudyofBioconductanceMeasurementwith18FDG-PETinEvaluationCTDetectedLungLesionSuspiciousforLungCancer

APreliminaryComparisonStudyofBioconductanceMeasurement...

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2016中华医学会呼吸病学年会暨第十七次全国呼吸病学学术会议

作者： DaweiYang JingLi XinGong RexYung ChunxueBai DepartmentofPulmonaryMedicine ZhongshanHospitalFudanUniversity ChineseAllianceAgainstLungC DepartmentofPulmonaryMedicine ZhongshanHospitalFudanUniversity ShanghaiRespiratoryResearchI GreaterBaltimoreMedicalCenter

目的 InChina,lungcanceristheleadingcauseofcancer***scanisusedinthestandardevaluationofabnormallunglesionssuspiciousforbeinglungcancer.18Fluoro-DeoxyGlucose-PositronEmission-Tomography(18FDG-PET)metabolicscanningcanbeusedasahelpfulimagingbiomarkertothefunctionalevaluationoflunglesions,butitisexpensiveandcanhave***ComputedBioconductance(CB)havebeenshowntodifferentiatebetweenmalignantandbenignlung***studycomparescomputedbioconductance(CB)measurementwith18FDG-PETtoanalyzehowtheycouldimprovetheassessmentofsuspiciouslunglesionfoundbyCT.

关键词： LungCancer Lunglesion PET-CT RiskStratification ComputedBioconductance

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