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检索条件"任意字段=2017(第三届)毒性测试替代方法与转化毒理学(国际)学术研讨会"
261 条 记 录,以下是211-220 订阅
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N-acetylcysteine Attenuates Paraquat-Induced Apoptosis and Autophagy in murine Neural Progenitor Cells
N-acetylcysteine Attenuates Paraquat-Induced Apoptosis and A...
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2017(第三届)毒性测试替代方法与转化毒理学(国际)学术研讨会
作者: Lina Zhao Guiya Xiong Chunhua Wu Xiuli Chang School of Public Health and Key Laboratory of Public Health Safety of the Ministry of Education Fudan University
Paraquat(PQ) is widely used bipyridyl herbicide in agriculture due to its fast action and low *** can induce neurotoxicity via oxidative *** study aimed to investigate the potential protective effect of NAC on the PQ-... 详细信息
来源: 评论
Fine particle matters induce DNA damage and G2/M cell cycle arrest in human bronchial epithelial BEAS-2B cells
Fine particle matters induce DNA damage and G2/M cell cycle ...
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2017(第三届)毒性测试替代方法与转化毒理学(国际)学术研讨会
作者: Jing Wu Yanfeng Shi Collins Otieno Asweto Lin Feng Xiaozhe Yang Yannan Zhang Hejing Hu Junchao Duan Zhiwei Sun Department of Toxicology and Sanitary Chemistry School of Public HealthCapital Medical University Beijing Key Laboratory of Environmental Toxicology Capital Medical University
There is compelling evidence that exposure to the particulate matter(PM) is linked to the lung *** this study,we investigated the toxic effects and molecular mechanisms of PM2.5 on the bronchial epithelial(BEAS-2 B) *... 详细信息
来源: 评论
iSafeRabbit High Accuracy QSAR to predict the Skin and Eye Irritation/Corrosion potential of individual constituents and mixtures
iSafeRabbit High Accuracy QSAR to predict the Skin and Eye I...
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2017(第三届)毒性测试替代方法与转化毒理学(国际)学术研讨会
作者: Faizan SAHIGARA Carole CHARMEAU-GENEVOIS Pascal BICHEREL Mélissa PEREA Satinder SARANG Tom AUSTIN Chantal SMULDERS Paul THOMAS KREATiS CEHTRA Shell International Shell International Limited Shell International B.V
Academia,industry,and regulatory authorities are working towards minimising the use of animal tests by developing alternative approaches such as QSARs and Read-Across *** REACH regulations,EU ban on animal testing for... 详细信息
来源: 评论
Modernizing Toxicology and Risk Assessment——Current Status,Regulatory Acceptance and Future Outlook
Modernizing Toxicology and Risk Assessment——Current Status...
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2017(第三届)毒性测试替代方法与转化毒理学(国际)学术研讨会
作者: Karen Blackburn Procter & Gamble Co
Historically,risk assessments for consumer product ingredients have relied on animal testing(principally in rodents) as a basis for establishing *** it is recognized that rodents are not necessarily a good model for h... 详细信息
来源: 评论
Genome-wide identification and functional analysis of long noncodingRNAs involved in the response to graphene oxide
Genome-wide identification and functional analysis of long n...
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2017(第三届)毒性测试替代方法与转化毒理学(国际)学术研讨会
作者: Qiuli Wu Dayong Wang Medical School of Southeast University
Due to the specific physiochemical properties,graphene oxide(GO),a member of graphene family,is a promising technology with the potential for many industrial and biomedical *** noncoding RNAs(IncRNAs),which are define... 详细信息
来源: 评论
Cr(Ⅵ) induces cytotoxicity in vitro through activation of ROS-mediated endoplasmic reticulum stress and mitochondrial dysfunction via the PI3K/Akt signaling pathway
Cr(Ⅵ) induces cytotoxicity in vitro through activation of R...
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2017(第三届)毒性测试替代方法与转化毒理学(国际)学术研讨会
作者: Yujing Zhang Zhang Yiyuan Fang Xiao Caigao Zhong Zeng Ming Department of Toxicology School of Public HealthCentral South University
The occupational and environmental toxicant hexavalent chromium[Cr(Vr)]can cause severe damage to the liver;however,the exact mechanisms associated with its toxicity have not been thoroughly *** the present study,the ... 详细信息
来源: 评论
Dynamical Systems Modeling of Thyroid Disruption by Environmental Endocrine Active Chemicals
Dynamical Systems Modeling of Thyroid Disruption by Environm...
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2017(第三届)毒性测试替代方法与转化毒理学(国际)学术研讨会
作者: Qiang Zhang Department of Environmental Health Rollins School of Public HealthEmory University
While cell or organoid-based in vitro assays are making headway to replace traditional animal-based approaches for chemical toxicity testing,a major challenge remaining is the lack of our capability of translating in ... 详细信息
来源: 评论
Chronic Cadmium Exposure:Changing Expression of RANKL/OPG in Mesenchymal Stem Cells and Autophagy-Related Proteins in Kidney and Brain
Chronic Cadmium Exposure:Changing Expression of RANKL/OPG in...
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2017(第三届)毒性测试替代方法与转化毒理学(国际)学术研讨会
作者: Lv Yingjian Huang Junming Li Bosheng Tan Jianbin Liu Qun Wu Chunfei Luo Jiezhen Yang Xingfen Guangdong Provincial Center for Disease Control and Prevention
Objectives To study the early effects of Mesenchymal Stem Cells(MSCs) and changes in protein expression in kidney and brain of long-term exposure to cadmium(Cd).Methodst 24 Sprague Dawley female rat were randomly ... 详细信息
来源: 评论
Threshold of Toxicological Concern(TTC) For Botanicals——Data Analysis To Substantiate And Extend The TTC Approach To Botanicals
Threshold of Toxicological Concern(TTC) For Botanicals——Da...
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2017(第三届)毒性测试替代方法与转化毒理学(国际)学术研讨会
作者: D.A.McMillan K.Kosemund C.Mahony M.Huber P.Bowtell T.Zhu The Procter & Gamble Company
Botanicals are complex mixtures of mostly unknown natural chemical constituents and classical toxicological data are often *** some botanicals are used broadly by humans as food,flavors/spices,or medicines,other botan... 详细信息
来源: 评论
Atrazine induced the reproductive toxicity in male quail
Atrazine induced the reproductive toxicity in male quail
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2017(第三届)毒性测试替代方法与转化毒理学(国际)学术研讨会
作者: Lei Qin Ming Jiang Lin Ding Yu-Chao Liu Hai-Yan Zhang Li Zhou Health Inspection Center Qiqihar Medical University
Objective:The aim of this article is to investigate the effects of atrazine exposure on the development of reproductive organ and reveal the reproductive toxicity in male ***:Eighty 18-day-old male quails were treated... 详细信息
来源: 评论