The diversified development of network applications and the informatization of social life are triggering explosive growth of data. The core journal articles based on big data research in the 2011-2018 database, which...
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Aluminum alloy has been widely used as a metal material. However, it is usually vulnerable to corrosion, so the protection of aluminum alloy surface is particularly important. At present, the commonly used methods of ...
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In today's world due to ever increasing demand to make computers perform tasks of humans, machinelearning is used. It is a tedious task to manually read the entire book and classify it based on its genre. Novice ...
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ISBN:
(纸本)9781538659335
In today's world due to ever increasing demand to make computers perform tasks of humans, machinelearning is used. It is a tedious task to manually read the entire book and classify it based on its genre. Novice writers find it troublesome to figure out the genre of their book, which can affect its reach to the right audience. The proposed method gains knowledge from a large number of words from the books and transforms them into a feature matrix. During transformation, the size of the initial matrix is reduced using Wordnet and Principle Component Analysis. Then, AdaBoost classifier is applied to predict the genres of the books.
The matrix factorization recommendation algorithm does not consider characteristics of the recommendation object itself, resulting in poor recommendation results. Therefore, a matrix factorization recommendation algor...
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Background: Early-phase clinical trials of protein arginine methyltransferase 5 (PRMT5) inhibitors as synthetic lethal strategies have shown promising efficacy in methylthioadenosine phosphorylase (MTAP)-deleted tumor...
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Background: Early-phase clinical trials of protein arginine methyltransferase 5 (PRMT5) inhibitors as synthetic lethal strategies have shown promising efficacy in methylthioadenosine phosphorylase (MTAP)-deleted tumors. To refine and expand this promising therapeutic approach within the framework of precision oncology, it is critical to comprehensively characterize the clinical and molecular profiles of MTAP-deleted tumors. Materials and methods: This pan-cancer retrospective cohort study analyzed clinico-genomic data from the Center for Cancer Genomics and Advanced Therapeutics (C-CAT) database, which includes 99.7% of patients who underwent comprehensive genomic profiling (CGP) in Japan between June 2019 and November 2023. machinelearning and explainable artificial intelligence methods were applied to identify clinical predictors of MTAP deficiency. Findings were validated and compared using The Cancer Genome Atlas (TCGA) and American Association for Cancer Research (AACR) Genomics Evidence Neoplasia Information Exchange (GENIE) datasets. Results: Among 51 828 pan-cancer patients in the C-CAT cohort, MTAP deletion was observed in 4964 cases (9.6%), with a high prevalence in pancreatic (18.4%), biliary tract (15.6%), and lung (14.3%) cancers. MTAP deletion was associated with distinct clinical features, including male sex (56.0% versus 47.8%), older age (mean 62.4 versus 59.8 years), and shorter interval from diagnosis to CGP (median 380.0 versus 567.0 days). In pancreatic cancer, MTAP deletion was more common in KRAS-mutant tumors (19.8%) compared with KRAS wild-type tumors (8.9%). Across cancer types, MTAP deletion was less frequent in RB1-mutant tumors (pan-cancer: 3.2%, pancreatic: 7.6%, lung: 2.5%, biliary tract: 5.4%) than in RB1 wild-type tumors (9.9%, 18.7%, 16.1%, 16.0%). These findings were validated using the TCGA (n = 9896) and GENIE (n = 178 034) datasets. In lung adenocarcinoma, MTAP deletion was found in 22.8% of EGFR-mutated tumors, 25.0% of ALK-tr
Tag collision problems are a major issue affecting the performance of RFID systems. The probabilistic tag anti-collision algorithm has tag starvation and cannot identify some tags. This paper proposes a deterministic ...
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In the current Capitalist world with an abundance of different state-of-the-art industries and fields cropping up, ushering in an influx of jobs for motivated and talented professionals, it is not difficult to identif...
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ISBN:
(纸本)9781538659335
In the current Capitalist world with an abundance of different state-of-the-art industries and fields cropping up, ushering in an influx of jobs for motivated and talented professionals, it is not difficult to identify your field and to persevere to get a job in the respective field but lack of information and awareness render the task difficult. This problem is being tackled by Job Recommendation systems. But not every aspect from the wide spectrum of factors is incorporated in the existing systems. For the "Job Recommendation System - Vitae" machinelearning and data mining techniques were applied to a RESTful Web Server application that bridges the gap between the Frontend (Android Application) and the Backend (MongoDB instance) using APIs. The data communicated through APIs is fed into the database and the Recommendation System uses that data to synthesize the results. To make the existing systems even more reliable, here efforts have been done to come up with the idea of a system that uses a wide variety of factors and is not only a one-way recommendation system.
This paper aims to find out the influence of guidance learning and monitoring on autonomous learning for College English. By applying the qualitative and quantitative research approach, we tested the efficiency of the...
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In order to study the effect of feeding Ginkgo leaf fermentation and Chinese herbal medicine on meat duck, we added Ginkgo leaf fermentation and Chinese herbal medicine additive to the daily feed of meat ducks, and se...
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In the past, studies tended to classify mutual funds according to arbitrary definitions. In this paper, we appliedmachinelearning techniques to assist the process. Compared to artificial selection, our classificatio...
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