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Parallel Exploration of the Nuclear Chromosome Conformation with NuChart-II 23

Parallel Exploration of the Nuclear Chromosome Conformation ...

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23rd Euromicro international conference on Parallel, distributed, and Network-Based Processing (PDP)

作者： Tordini, Fabio Drocco, Maurizio Misale, Claudia Milanesi, Luciano Lio, Pietro Merelli, Ivan Aldinucci, Marco Univ Turin Dept Comp Sci I-10124 Turin Italy Univ Cambridge Comp Lab Cambridge CB2 1TN England Italian Natl Res Council Inst Biomed Technol Segrate Mi Italy

ISBN: (纸本)9781479984909

High-throughput molecular biology techniques are widely used to identify physical interactions between genetic elements located throughout the human genome. Chromosome Conformation Capture (3C) and other related techniques allow to investigate the spatial organisation of chromosomes in the cell's natural state. Recent results have shown that there is a large correlation between co-localization and co-regulation of genes, but these important information are hampered by the lack of biologists-friendly analysis and visualisation software. In this work we introduce NuChart-II, a tool for Hi-C data analysis that provides a gene-centric view of the chromosomal neighbourhood in a graph-based manner. NuChart-II is an efficient and highly optimized C++ re-implementation of a previous prototype package developed in R. Representing Hi-C data using a graph-based approach overcomes the common view relying on genomic coordinates and permits the use of graph analysis techniques to explore the spatial conformation of a gene neighbourhood.

关键词： systems Biology Parallel computing Hi-C data Neighbourhood Graph Chromosome Conformation Capture

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TCP/IP Model and Intrusion Detection systems

TCP/IP Model and Intrusion Detection Systems

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23rd international conference on Advanced Information Networking and Applications workshops

作者： Zaman, Safaa Karray, Fakhri Univ Waterloo ECE Dept Waterloo ON N2L 3G1 Canada

ISBN: (纸本)9781424439997

To accommodate the information security growth and hacker's improved strategies and tools, Intrusion Detection systems (IDSs) are required to be allocated across the network. Furthermore, previous studies showed that the choice of network features used for the IDS is dependent on the type of the attack. Accordingly, each TCP/IP network layer has specific type of network attacks, which means that each TCP/IP network layer needs a specific type of IDS. This paper proposes a new categorization for IDS depending on the TCP/IP network model: Application layer IDS (AIDS), Transport layer IDS (TIDS), Network layer IDS (NIDS) and Link layer IDS (LIDS). Each of these IDS types is specialized to a specific network device. So, the detection process will be distributed among all TCP/IP network model layers through the network devices. To design each of these different types of IDS, several experiments have been conducted using two different features selection approaches to select the appropriate features set for each IDS type. The experimental results indicate that each EDS type has different features set that can not only improve the overall performance of the IDS, but it also can improve its scalability.

关键词： Intrusion detection systems TCP/IP network model features selection features ranking support vector machines support vector decision function

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FCatch: Automatically Detecting Time-of-fault Bugs in Cloud systems 18

FCatch: Automatically Detecting Time-of-fault Bugs in Cloud ...

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23rd international conference on Architectural Support for Programming Languages and Operating systems (ASPLOS)

作者： Liu, Haopeng Wang, Xu Li, Guangpu Lu, Shan Ye, Feng Tian, Chen Univ Chicago Chicago IL 60637 USA Beihang Univ Beijing Peoples R China Huawei US R&D Ctr Santa Clara CA USA

ISBN: (纸本)9781450349116

It is crucial for distributed systems to achieve high availability. Unfortunately, this is challenging given the common component failures (i.e., faults). Developers often cannot anticipate all the timing conditions and system states under which a fault might occur, and introduce time-of-fault (TOF) bugs that only manifest when a node crashes or a message drops at a special moment. Although challenging, detecting TOF bugs is fundamental to developing highly available distributed systems. Unlike previous work that relies on fault-injection to expose TOF bugs, this paper carefully models TOF bugs as a new type of concurrency bugs, and develops FCatch to automatically predict TOF bugs by observing correct execution. Evaluation on representative cloud systems shows that FCatch is effective, accurately finding severe TOF bugs.

关键词： Timing Bugs Fault Tolerance distributed systems Bug Detection Cloud computing

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Tutorial: OMG data distribution service

Tutorial: OMG data distribution service

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international conference on distributed computing systems Workshop

作者： H.-A. Jacobsen Head of C2 and Combat Systems Office of Naval Research Arlington VA USA

In many distributed applications, communication patterns follow a data-centric message exchange style of interaction, where applications publish data and other applications express interest in this data by subscribing to it. Applications of this sort can be found in industrial automation, the C4I sector (command, control, communications, computers and intelligence), telecom equipment control, sensor networks, and network management.

关键词： Tutorial Application software Automatic control Communication system control Telecommunication control Intelligent sensors Communication industry Computer industry Industrial control Automation

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Financial management in the era of distributed computing

Financial management in the era of distributed computing

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Proceedings of the 1997 23rd international conference for the Resource Management & Performance Evaluation of Enterprise computing systems. Part 1 (of 2)

作者： Cook, James R. Systems Management Consultants

As the importance of information technology to the business has grown exponentially, over the last five decades, the approaches to financial management of IT have remained relatively static. Thus enterprises stand poised on the brink of the new millennium, in which the exploitation of information technologies will be the key differentiator between winners and losers, armed with financial practices designed to control limited, centralized, non-strategic support equipment. It is not hyperbole to say that the financial practices most enterprises use to manage their distributed information systems is less sophisticated than those they employ to manage their photocopiers. In this paper, the author discusses how to apply a new metrics collection technology which is not specifically designed to support IT accounting and chargeback and describes how to model the costs of these metrics via a simplified, activity-based approach.

关键词： Information technology

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Understanding Asynchronous distributed Collaboration in an Enterprise systems Engineering Context

Understanding Asynchronous Distributed Collaboration in an E...

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23rd international conference on systems Engineering

作者： Klein, Gary L. Drury, Jill L. Condon, Sherri L. Mitre Corp Mclean VA 22102 USA Mitre Corp Bedford MA 01730 USA

ISBN: (纸本)9783319084213

End users-even though they may be distributed geographically and across time zones-can play a substantial and beneficial role in the enterprise systems engineering (ESE) process. However, it is difficult to support asynchronous distributed collaboration under typical workplace conditions, and it is even more challenging to do so in the context of a complex ESE effort that includes multiple, interdependent, supportive ESE methods and techniques. This paper presents our model of such efforts and describes the demands each model component places on asynchronous distributed collaboration during system development. Further, this paper explains how we have used the model to develop an interview protocol to probe for the presence of model components in individual ESE efforts and their levels of success in managing these variables. © Springer international Publishing Switzerland 2015.

关键词： asynchronous collaboration collaboration computer-supported cooperative work CSCW distributed collaboration end users enterprise systems engineering ESE

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A connector-aware middleware for distributed deployment and mobility

A connector-aware middleware for distributed deployment and ...

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international conference on distributed computing systems Workshop

作者： M. Mikic-Rakic N. Medvidovic Computer Science Department University of Southern California Los Angeles CA USA

To address the need for highly configurable and customizable distributed systems, researchers and practitioners are investigating various innovative approaches. One of the promising techniques emerging from this area of study is mobile computing. In this paper we present an architecture-based approach to supporting distributed deployment and mobility of software systems. We exploit a connector-aware architectural middleware in providing these capabilities. The approach has been successfully tested on several applications for networks of small, mobile, resource constrained devices (e.g., hand-held computers).

关键词： Middleware Connectors Dispatching Runtime Computer science distributed computing conferences Routing Yarn Data security

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A hybrid genetic algorithm for process scheduling in distributed operating systems considering load balancing

A hybrid genetic algorithm for process scheduling in distrib...

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IASTED international conference on Parallel and distributed computing and Networks, as part of the 23rd IASTED international Multi-conference on Applied Informatics

作者： Haghighat, A.T. Nikravan, M. Department of Electrical Computer and IT Islamic Azad University Qazvin Branch Qazvin Iran NPPD Tehran Iran Department of Electrical Computer and IT Islamic Azad University Tehran South Branch Tehran Iran

This paper presents and evaluates a new method for process scheduling in distributed systems. Scheduling in distributed operating systems has a significant role in overall system performance and throughput. An efficient scheduling is vital for system performance. The scheduling in distributed systems is known as an NP-complete problem even in the best conditions, and methods based on heuristic search have been proposed to obtain optimal and suboptimal solutions. In this paper, we combine the power of genetic algorithms and simulated annealing to solve this problem considering load balancing efficiently. We evaluate the performance and efficiency of the proposed algorithm in comparison with other existing traditional and heuristic algorithms using simulation results. The proposed GA-Based algorithm has overcome the existing algorithms considering running time.

关键词： distributed computer systems

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Towards a definition of the real-time data distribution problem space

Towards a definition of the real-time data distribution prob...

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international conference on distributed computing systems Workshop

作者： A. Uvarov V. Fay-Wolfe Department of Computer Science University of Rhode Island Kingston RI USA

This paper describes a set of characteristics that partially make up the problem space for real-time data distribution. The characteristics are divided into three groups: system characteristics, real-time characteristics, and data characteristics. The paper describes each of the characteristics, and then illustrates them with two current proposed solutions to real-time data distribution problem.

关键词： Real time systems Automation Space exploration Taxonomy Computer science Industrial electronics Electronics industry Timing Sensor systems and applications Data communication

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23rd international conference on Parallel and distributed computing, Euro-Par 2017

23rd International Conference on Parallel and Distributed Co...

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23rd international conference on Parallel and distributed computing, Euro-Par 2017

ISBN: (纸本)9783319642024

The proceedings contain 51 papers. The special focus in this conference is on Parallel and distributed computing. The topics include: computing just what you need: online data analysis and reduction at extreme scales;scaling energy adaptive applications for sustainable profitability;off-road performance modeling – how to deal with segmented data;online dynamic monitoring of MPI communications;micro-benchmarking mpi neighborhood collective operations;performance characterization of de novo genome assembly on leading parallel systems;NVIDIA jetson platform characterization;following the blind seer – creating better performance models using less information;an accurate simulator of cache-line conflicts to exploit the underlying cache performance;shutdown policies with power capping for large scale computing systems;partitioning strategy selection for in-memory graph pattern matching on multiprocessor systems;efficient dynamic pinning of parallelized applications by reinforcement learning with applications;accelerating by idling: how speculative delays improve performance of message-oriented systems;optimizing egalitarian performance in the side-effects model of colocation for data center resource management;generic algorithms for scheduling applications on hybrid multi-core machines;low-cost approximation algorithms for scheduling independent tasks on hybrid platforms;runtime-assisted shared cache insertion policies based on re-reference intervals;rewriting system for profile-guided data layout transformations on binaries;hardware support for scratchpad memory transactions on GPU architectures;execution of recursive queries in apache spark;replica-aware partitioning design in parallel database systems;a simplified model for simulating the executionof a workflow in cloud;dealing with performance unpredictability in an asymmetric multicore processor cloud;deadline-aware deployment for time critical applications in clouds;an efficient communication aware heuristic for mul

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