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international conference on BioMedical Engineering and Informatics (BMEI)

作者： Ying Wang Yingxi Liu Xiuzhen Sun Zhaoyue Chen Fei Gao State Key Laboratory of Structural Analysis of Industrial Equipment Dalian University of Technology Dalian Liaoning China Department of Otorhinolaryngology Second Affiliated Hospital Dalian Medical University Dalian Liaoning China

ISBN: (纸本)9781424441327

Adenoidectomy is a common surgical procedure performed on children with Obstructive Sleep Apnea (OSA). Owing to lack of objective data, the studies on evaluation postoperative outcomes have been limited. The present study takes computational fluid dynamics (CFD) approach to assessing postoperative effect in children with OSA undergoing adenoidectomy by comparison of the flow field characteristics between postoperative with preoperative upper airway. The computational fluid dynamics models were constructed using raw data from preoperative and postoperative computed tomogram images of three children with OSA. Considering three-dimensional transient turbulent flow in the airway, flow field was solved for a cycle of normal breathing. The simulation results are validated by the clinical measurements and results in literature. It is shown that the airflow patterns in postoperative nasopharyngeal airway are significantly different from preoperative subjects. The resistance in nasopharyngeal passage can be an objective parameter to evaluate the treatment effects.

关键词： Sleep apnea computational fluid dynamics Surgery Pediatrics Computed tomography Hospitals Biomedical imaging Predictive models computational modeling Computer industry

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A Bayesian Approach to Weibull Survival Model for Clinical Randomized Censoring Trial Based on MCMC simulation

A Bayesian Approach to Weibull Survival Model for Clinical R...

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The 2nd international conference on Bioinformatics and Biomedical Engineering(iCBBE 2008)(第二届生物信息与生物医学工程国际会议)

作者： Xujie Zhao Chao Yu Hengqing Tong Department of Mathematics Wuhan University of Technology Wuhan Hubei 430070 P.R.China

Survival analysis for randomized censored data is common in clinical trial. Among various survival models proposed to deal with such censoring, Weilbull regression model is widely used as one of accelerated failure time models, because it's flexible to suit different applications. It's well known that Bayesian analysis has the advantage in dealing with censored data and small sample over frequentist methods. Therefore, this paper presents the Weibull regression model for randomized censored data from Bayesian perspective, and then computes the Bayesian estimator based on the Markov Chain Monte Carlo (MCMC) method. The Gibbs sampling is proposed to simulate the Markov chain of parameters' posterior distribution dynamically, which avoids the calculation of complex integrals of the posterior distribution effectively. Finally the simulation with real clinical data of lymph sarcoma is presented. The whole procedure is implemented by the freely available software WinBUGS.

关键词： Bayesian methods Mathematics Clinical trials Sampling methods Analytical models Monte Carlo methods computational modeling Application software Diseases Mathematical model

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Image-based meshing of patient-specific data: Converting medical scans into highly accurate computational models

Image-based meshing of patient-specific data: Converting med...

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The 2nd international conference on Bioinformatics and Biomedical Engineering(iCBBE 2008)(第二届生物信息与生物医学工程国际会议)

作者： Rajab Said Jenssen Chang Gavin Tabor Philippe Young Sam Coward Simpleware Ltd. Exeter United Kingdom Shanghai Gaitech Scientific Instruments Shanghai China School of Engineering Computing and Mathematics University of Exeter Exeter United Kingdom

computational simulation technology has become an indispensable tool for researchers across the biomechanics discipline. Crucial to the effectiveness of such a tool is its ability to efficiently simulate patient-specific problems. This paper will present a unique and exceptionally efficient approach that converts 3D digital images (provided typically by CT, Ultrasound or MRI scanners) directly into highly accurate computational models. Two case studies will be presented, including the virtual positioning of a hip implant within a scan, and the insertion of a cannula into a human artery. Both studies investigate the effect of certain surgical procedures by using image-based models.

关键词： Biomedical modeling image processing image-based meshing finite element analysis (FEA) computational fluid dynamics (CFD) orthopaedics blood flow

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The Hemodynamic Effects analysis of the New CPR Technique-Electro Ventilation Double Pump CPR: Studies in the Computer Model

The Hemodynamic Effects Analysis of the New CPR Technique-El...

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international conference on Bioinformatics and Biomedical Engineering (ICBBE)

作者： Xiaoming Wu Xu Lin Yanru Zhang Qiong Liu Hengxin Yuan School of Computer Science and EngineeringSouth China University of TechnologyGuangzhou P.R.China School of Computer Science and Engineering South China University of Technology Guangzhou P.R. China South China University of Technology Guangzhou Guangdong CN School of Bioscience and BioengineeringSouth China University of TechnologyGuangzhou P.R. China Institute of Biomedical EngineeringSun Yat-Sen University Medical CollegeSun Yat-Sen UniversityGuangzhou P.R. China

To study the hemodynamic effects during human cardiac arrest and compare the new cardiopulmonary resuscitation (CPR) technique- electro ventilation double pump CPR (EDCPR) with standard CPR by building a computer model of human circulation. Developing a computer model of circulatory system; performing the effects of Standard CPR and EDCPR to the model respectively; comparing the computer simulating results. Enhanced external countpulsation (EECP) got the better hemodynamic effects than standard CPR And it was in accordance with the results of parallel animal experiments and the data published before. The developed model can successfully describe the effects of different CPR techniques to the circulation system during cardiac arrest.

关键词： Hemodynamics Ventilation Humans Cardiac arrest Cardiology Circulatory system Standards development computational modeling Computer simulation Standards publication

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computational model for the study of the fractal parameters characteristic for the surface of titanium dental implants

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Communications in Computer and Information Science 2008年 13卷 571-580页

作者： Pusca, Stefan Toma, Theodora Politehnica University Department of Physics Bucharest Romania Smart Edu Software Publishing LTD Bucharest Romania

ISBN: (纸本)9783540705987

In order to check if the Fractal theory could be a useful tool for some quantitative descriptions of the fracture parameters, the present work studied diferent theoretical models. The possibility of using different theoretical models (e.g. the Bazant's Size Efect Law (SEL) [1], the Modifed Size Efect Law [2, 3] and the Carpinteri's MultiFractal Scaling Law (MFSL) [4] wich have been already confirmed for the fracture parameters of concrete specimen, and the compatibility of some of the above studied theoretical models relative to the experimental data, using certain recent procedures to study the global and local compatibility have been analysed. The fracture parameters can be considered as main quantities for computational procedures for modeling the fracture of a certain ensemble (a suddenly emerging phenomena). In the next phase, the thermoelastic generation of ultrasonic perturbations in titanium implant material coated with hidroxiapatite was analyzed (using computer simulation) so as to find similarities with material properties as fractal dimensions. The algorithm, the numerical analysis has taken into account three main physical phenomena: the absorption of electromagnetic energy in substance with heat generation;thermal difusion with electromagnetic energy based heat source and elastodynamic wave generation by thermoelastic expansion. © Springer-Verlag Berlin Heidelberg 2008.

关键词： Electromagnetic waves

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Using an automated approach to explore and design a high-efficiency processor element for the multimedia domain

Using an automated approach to explore and design a high-eff...

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2nd international conference on Complex, Intelligent and Software Intensive Systems

作者： Lai Mingche Guo Jianjun Zhang Zhuxi Wang Zhiying Natl Univ Def Technol Sch Comp Changsha Hunan Peoples R China Logist Res Inst Beijing Peoples R China

ISBN: (纸本)9780769531090

This paper presents the exploration and design of a high-efficiency processor element for multimedia application. Based on the cost estimation model to evaluate the area and energy consumption for synchronous data transport architecture, a divide-and-conquer design approach is proposed to generate the optimal processor element in a short time. The computing core exploration begins with the application characteristics analysis, and continues with a heuristic search process for the performance-energy Pareto optimal cores. Then, the trace-driven simulation and analytical method explore the processor elements which are optimal with respect to performance-energy under area constraint. The automated design approach generates the target processor element within 4 hours, and the processor implemented in UMC 0.13um CMOS process can operate at 500MHz while consuming average 223mW power. For multimedia applications, the generated processor has the comparable performance with the state-of-art high performance DSPs.

关键词： computational modeling Mathematical model Registers Computer architecture Multimedia communication Equations Sockets

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Application of a dynamic computational gis modeling methodology for exposure and dose risk assessment

Application of a dynamic computational gis modeling methodol...

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2nd IASTED international conference on Environmental Modelling and simulation

作者： Magro, G. Scarpanti, S. Sumini, M. Teodori, F. Univ Bologna Dept Energy & Nucl Engn Environm Control Via dei Colli 16 I-40136 Bologna Italy

ISBN: (纸本)9780889866171

An application of Dynamic computational G.I.S methodology in an Exposure Risk Assessment and Dose Assessment based on numerical matrix interaction is here presented. Dynamic computational G.I.S. (DCGIS) is a methodology based on U.S E.P.A. Ecological Risk Assessment and Exposure Assessment Guidelines. Such a methodology is supported by a newly developed Java based software tool working by means of the setup of stressor-vulnerability maps correlations. In this framework it is possible to set several kinds of correlations between stressor matrixes and vulnerability maps in order to compute multi-level risk maps for any specific correlation frame. The software tool produces also technical reports with numerical data concerning the exposure surfaces and the specific dose distribution. The domain of the assessed area can be characterized in a grid-matrix frame and several stressor matrixes can be set for each emission source. The software tool analyser produces comparative risk maps, which are useful for both assessors and managers, mainly when they need different information levels. It is significant to say that the methodology is very appropriate for cumulative and/or interacting effects evaluation which are strategically important in planning activities involving also wide critical areas with ecological protected sites, population centres and industrial developments.

关键词： assessment geographic information systems dynamic GIS stressor-vulnerability analysis dose exposure

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System For Physical Processes simulation In Hydraulic Microelectromechanical Systems

System For Physical Processes Simulation In Hydraulic Microe...

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international conference on Perspective Technologies and Methods in MEMS Design (MEMSTECH)

作者： Pavlo Denysyuk Vasyl Teslyuk Mykhaylo Lobur Ihor Farmaga Roman Abramovych

In the article problems of program-methodical system development for physical processes analysis in hydro-and gas dynamic systems are considered

关键词： Microelectromechanical systems Object oriented modeling Mathematical model Buildings Modems data preprocessing Visualization computational modeling Fabrication Computer industry

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Fuzzy modeling in Response Surface Method for Complex Computer Model Based Design Optimization

Fuzzy Modeling in Response Surface Method for Complex Comput...

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IEEE/ASME international conference on Mechtronic and Embedded Systems and Applications, MESA

作者： Ruoning Xu Zuomin Dong School of Information and Electro-Mechanical Engineering Guangzhou University Guangzhou China Department of Mechanical Engineering University of Victoria Victoria BC Canada

Metamodel based optimization serves as an effective tool for carrying out multi-disciplinary and multi-objective design optimization using complex, "black box" computer modeling, analysis and simulation tools. The response surface based metamodeling method uses simple surrogate polynomial model to approximate the complex objective and constraint functions to reduce computation time, thus making prohibitive global optimization requiring extensive computation feasible. In this paper, another important issue in metamodeling, the uncertainty of the result data from the "black box" functions and their appropriate processing are addressed. The newly introduced fuzzy modeling method inherits the advantages of the well tested response surface method and removes a major fault assumption of the approach on sure result data, thus leading to better accuracy to the identified design optimum. The close form solution of the second order response surface model in fuzzy setting has been derived and demonstrated using a bench mark global design optimization problem

关键词： Response surface methodology Design optimization Metamodeling computational modeling Analytical models Computer simulation Polynomials Constraint optimization Uncertainty Testing

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AgentJ: Enabling Java NS-2 simulations for Large Scale Distributed Multimedia Applications

AgentJ: Enabling Java NS-2 Simulations for Large Scale Distr...

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international conference on (DFMA) Distributed Frameworks for Multimedia Applications

作者： Ian Taylor Brian Adamson Ian Downard Joe Macker PROTEAN Group Contractor School of Computer Science Cardiff University Cardiff UK Protocol Engineering and Advanced Networking PROTEAN Research Group U. S. Naval Research Laboratory Washington D.C. DC USA

We present a framework, called AgentJ that extends the NS-2 platform to support the simulation and performance analysis of Java network applications. We particularly focus on the simulation of P2P networks and have already integrated the P2PS middleware for the simulation of super-peer networks for discovering participants in large scale Internet applications, which has a high significance for distributed multimedia applications to enable overlays for the discovery and searching across large numbers of distributed multimedia resources. AgentJ builds upon the numerous years of networking research with NS-2 and leverages the Protolib toolkit from NRL to facilitate the passing of real data between NS-2 nodes, thereby creating a platform for the simulation of content-based middleware and applications. AgentJ currently supports UDP unicast and multicast and maintains compatible programming interfaces with the standard Java network package as well as the NS-2 scripting interfaces employed for staging simulations

关键词： Java Large-scale systems Application software Protocols Peer to peer computing Middleware Analytical models computational modeling Computer simulation Computer science

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