This paper advocates the use of shape descriptors based on moments of 3D coordinates for morphometry of the cortical sulci. These descriptors, which have been introduced more than a decade ago, are invariant relativel...
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ISBN:
(数字)9783540399032
ISBN:
(纸本)3540204644
This paper advocates the use of shape descriptors based on moments of 3D coordinates for morphometry of the cortical sulci. These descriptors, which have been introduced more than a decade ago, are invariant relatively to rotations, symmetry and scale and can be computed for any topology. A rapid insight of the derivation of these invariants is proposed first. Then, their potential to characterize shapes is shown from a principal component analysis of the 12 first invariants computed for 12 different deep brain structures manually drawn from 7 different brains. Finally, these invariants are used to find some correlates of handedness among the shapes of 116 different cortical sulci automatically identified in 144 brains of the ICBM database.
MR guided interstitial laser therapy can be used to monitor the extent of tumor tissue coagulation during thermal treatment based on a temperature map. In a non-stationary object that was influenced by respiratory mot...
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ISBN:
(数字)9783540399032
ISBN:
(纸本)3540204644
MR guided interstitial laser therapy can be used to monitor the extent of tumor tissue coagulation during thermal treatment based on a temperature map. In a non-stationary object that was influenced by respiratory motion, the temperature map may show errors due to incorrect spatial baseline images. Moreover, an unwanted phase shift due to object displacement contributes to errors in the temperature map, that must be suppressed. This paper describes a strategy which addresses the difficulties of MR guided interstitial laser therapy in the presence of respiratory motion. The multi-baseline images, supported by the displacement correction scheme, were used to improve the temporal resolution of a temperature map in the respiratory cycle. In the displacement correction scheme, the object coordinates that are provided by an active tracking coil were employed to support a matching strategy between the thermal and baseline images. To avoid errors in the temperature map due to the motion artifact, a detector of low quality images was proposed as part of the displacement correction scheme.
During stereotactic surgery in the ventrolateral (V-L) thalamic nucleus we localized the motor fibers of the internal capsule (IQ by electrophysiological stimulation. Knowledge of the location and motor somatotopy in ...
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ISBN:
(数字)9783540399032
ISBN:
(纸本)3540204644
During stereotactic surgery in the ventrolateral (V-L) thalamic nucleus we localized the motor fibers of the internal capsule (IQ by electrophysiological stimulation. Knowledge of the location and motor somatotopy in the IC helps predict the boundaries of the VL. Although the somatotopy of the IC in individual patients is determined during their respective surgeries, quantitative analysis of somatotopic data from multiple subjects within a common magnetic resonance imaging (MRI) reference space has not been attempted. Here we describe a method for group analysis, in a single coordinate system, of responses obtained from the IC adjacent to the thalamus. We analyzed tongue, face, arm, and leg motor responses in 25 cases of thalamotomy. We used existing software to develop a three dimensional (31)) database of motor responses. Our preliminary analysis suggests a face-anterior to leg-posterior somototopic organization, with some overlap between adjacent representations.
This paper presents a new parallel algorithm for nonrigid image registration using off-the-shelf supercomputers, or clusters of PCs. Our algorithm realizes scalable registration for high resolution three-dimensional (...
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ISBN:
(纸本)3540204628
This paper presents a new parallel algorithm for nonrigid image registration using off-the-shelf supercomputers, or clusters of PCs. Our algorithm realizes scalable registration for high resolution three-dimensional (3-D) images by employing three techniques: (1) data distribution;(2) data-parallel processing;and (3) dynamic load balancing. The experimental results show that our parallel implementation on a cluster of 64 off-the-shelf PCs (with 128 processors) registers liver CT images of 512 x 512 x 159 voxels within 8 minutes while a sequential implementation takes 12 hours. Furthermore, our implementation allows processors to use less memory, and thereby enables us to align 1024 x 1024 x 590 voxel images, which is not easy for single processor systems due to the restrictions on the memory space and the processing time.
Diffusion Tensor Imaging (DTI) provides voxel-wise information related to the local diffusion anisotropy. Recent research efforts have centered around the use of this information to infer the direction of local fiber ...
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ISBN:
(数字)9783540399032
ISBN:
(纸本)3540204644
Diffusion Tensor Imaging (DTI) provides voxel-wise information related to the local diffusion anisotropy. Recent research efforts have centered around the use of this information to infer the direction of local fiber bundles. Calculation of the diffusion tensor and corresponding principle diffusion direction voxel-wise throughout the imaged volume permits the use of tracking algorithms to reconstruct the fiber-bundle pathways. These algorithms are typically based on line propagation and provide results that visually resemble anatomical fiber dissections. Despite the success of these methods, they suffer several limitations, particularly within regions of decreased anisotropy, such as areas of grey matter and fiber crossing or branching. In this paper we present an alternative method of DTI data visualization, line integral convolution (LIC), which has several advantages over existing techniques, particularly, the ability to deal with noise and singularities within the vector field and areas of low anisotropy.
A new augmented reality apparatus was evaluated. The device uses scanned infrared and visible lasers to project computer generated information such as surgical plans, entry pints for probes etc, directly onto the pati...
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ISBN:
(数字)9783540399032
ISBN:
(纸本)3540204644
A new augmented reality apparatus was evaluated. The device uses scanned infrared and visible lasers to project computer generated information such as surgical plans, entry pints for probes etc, directly onto the patient. In addition to projecting the plan, the device can be integrated with a 3D camera and is capable of measuring the location of projected infrared laser spots. This can be used to ensure that the display is accurate, apply corrections to the projection path and to assist in registration. The projection system has its own Application Programmer's Interface (API) and is a stand-alone add-on unit to any host computer system. Tests were conducted to evaluate the accuracy and repeatability of the system. We compared the locations of points projected on a flat surface with the measurements obtained from a tracked probe. The surface was rotated through 60 degrees in 5 degree increments and locations measured from the two devices agreed to within 2mm. An initial host application was also developed to demonstrate the new unit. Fiducials representing vertices along a proposed craniotomy were embedded into a plastic skull and a projection path defining the craniotomy was calculated. A feedback-based optimization of the plan was performed by comparing the measurement taken by the camera of these coordinates. The optimized plan was projected onto the skull. On average, the projection deviated by approximately 1mm from the plan. Applications include identification of critical anatomical structures, visualization of preplanned paths and targets, and telesurgery or teleconsultation.
Oblique-viewing endoscopes (oblique scopes) are widely used medically. It is essential for certain procedures such as laparoscopy, arthroscopy, and sinus endoscopy. In an oblique scope, its viewing directions are chan...
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ISBN:
(数字)9783540399032
ISBN:
(纸本)3540204644
Oblique-viewing endoscopes (oblique scopes) are widely used medically. It is essential for certain procedures such as laparoscopy, arthroscopy, and sinus endoscopy. In an oblique scope, its viewing directions are changeable by rotating the scope cylinder. Although a camera calibration method is necessary to apply augmented reality technologies to oblique endoscopic procedures, no method for oblique scope calibration has been developed yet. In the present paper, we formulate a camera model and a calibration procedure for oblique scopes. In the calibration procedure, Tsai's calibration is performed at zero-rotation of the scope cylinder, and then the variation of the external camera parameters corresponding to the rotation of the scope cylinder is modeled and estimated as a function of the rotation angle. Accurate estimation of the rotational axis is included in the procedure. The precision of this estimation was demonstrated to have a significant effect on the overall calibration accuracy in the experimental evaluation especially with large rotation angles. The projection error in the image plane was around two pixels. The proposed method was shown to be clinically applicable.
Manual quantitative analysis of cardiac left ventricular function using multi-slice CT is labor intensive because of the large datasets. In previous work, an intrinsically three-dimensional segmentation method for car...
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ISBN:
(纸本)3540204628
Manual quantitative analysis of cardiac left ventricular function using multi-slice CT is labor intensive because of the large datasets. In previous work, an intrinsically three-dimensional segmentation method for cardiac CT images was presented based on a 3D Active Shape Model (3D-ASM). This model systematically overestimated left ventricular volume and underestimated blood pool volume, due to inaccurate estimation of candidate points during the model update steps. In this paper, we propose a novel ASM candidate point generation method based on a Fuzzy Inference System (FIS), which uses image patches as an input. Visual and quantitative evaluation of the results for 7 out of 9 patients shows substantial improvement for endocardial contours, while the resulting volume errors decrease considerably (blood pool: -39 +/- 29 cubic voxels in the previous model, -0.66 +/- 6.2 cubic voxels in the current). Standard deviation of the epicardial volume decreases by approximately 50%.
We present an effective intensity-based method for rigid registration of a patient preoperative CT to its intraoperative situation with a few fluoroscopic X-ray images obtained with a tracked C-arm. It improves upon e...
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ISBN:
(纸本)3540204628
We present an effective intensity-based method for rigid registration of a patient preoperative CT to its intraoperative situation with a few fluoroscopic X-ray images obtained with a tracked C-arm. It improves upon existing methods and overcomes most of their intrinsic speed, robustness, and accuracy problems. For speed, we generate Digitally Reconstructed Radiographs on small, dynamically selected regions of interest from precomputed ray gray levels in expected viewing directions, and use a multiresolution hierarchy of fluoroscopic X-ray images. For robustness and accuracy, we use a two-step comparison measure: Normalized Cross Correlation followed by Variance Weighted Sum of Local Normalized Correlation. To avoid local minima, we use a genetic search method. Our experiments on simulated, in-vitro, and cadaver data show an overall mean Target Registration Error of 0.8mm (max=1.5mm), 95% of the time, computed in 20-100 seconds under realistic conditions.
We have developed a 3D ultrasound augmented reality (AR) workspace, in which the user wears a video-see-through head-mounted display to observe both 2D ultrasound (US) images and local 3D ultrasound volumes in-situ, i...
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ISBN:
(数字)9783540399032
ISBN:
(纸本)3540204644
We have developed a 3D ultrasound augmented reality (AR) workspace, in which the user wears a video-see-through head-mounted display to observe both 2D ultrasound (US) images and local 3D ultrasound volumes in-situ, i.e. in their actual location, overlaid onto a stereoscopic video view. In this unified platform, the user has the ability to reconstruct a local three-dimensional volume from a series of scanned two-dimensional US B-planes. In-situ visualization of rendered three-dimensional volumes facilitates the understanding of the object's three-dimensional structure. The user has full control over acquisition, reconstruction, and visualization of the volumetric data through an interactive, intuitive augmented reality user interface. Furthermore, the system has the ability to track a hand-held tool (e.g. biopsy needle). Graphically enhanced needle improves the perception of needle's position and orientation with respect to the lesion target in the rendered volume. In phantom experiments, our AR system has proven to effectively facilitate ultrasound guided needle biopsies. We have also verified biopsy results by reconstructing the "post-operative" volumes with the needle left in place.
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