In this paper we present a sequential expectation maximization algorithm to adapt in an unsupervised manner a Gaussian mixture model for a classification problem. the goal is to adapt the Gaussian mixture model to cop...
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this paper reports a voted Named Entity recognition (NER) system withthe use of appropriate unlabeled data. the proposed method is based on the classifiers such as Maximum Entropy (ME), Conditional Random Field (CRF)...
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Delineation of lung fields in presence of diffuse lung diseases (DLPDs), such as interstitial pneumonias (IP), challenges segmentation algorithms. To deal with IP patterns affecting the lung border an automated image ...
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Delineation of lung fields in presence of diffuse lung diseases (DLPDs), such as interstitial pneumonias (IP), challenges segmentation algorithms. To deal with IP patterns affecting the lung border an automated image texture classification scheme is proposed. the proposed segmentation scheme is based on supervised texture classification between lung tissue ( normal and abnormal) and surrounding tissue ( pleura and thoracic wall) in the lung border region. this region is coarsely defined around an initial estimate of lung border, provided by means of Markov Radom Field modeling and morphological operations. Subsequently, a support vector machine classifier was trained to distinguish between the above two classes of tissue, using textural feature of gray scale and wavelet domains. 17 patients diagnosed with IP, secondary to connective tissue diseases were examined. Segmentation performance in terms of overlap was 0.924 +/- 0.021, and for shape differentiation mean, rms and maximum distance were 1.663 +/- 0.816, 2.334 +/- 1.574 and 8.0515 +/- 6.549 mm, respectively. An accurate, automated scheme is proposed for segmenting abnormal lung fields in HRC affected by IP
Systems modeling and quantitative analysis of large amounts of complex clinical and biological data may help to identify discriminatory patterns that can uncover health risks, detect early disease formation, monitor t...
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ISBN:
(纸本)3642019285
Systems modeling and quantitative analysis of large amounts of complex clinical and biological data may help to identify discriminatory patterns that can uncover health risks, detect early disease formation, monitor treatment and prognosis, and predict treatment outcome. In this talk, we describe a machine-learning framework for classification in medicine and biology. It consists of a patternrecognition module, a feature selection module, and a classification modeler and solver. the patternrecognition module involves automatic image analysis, genomic patternrecognition, and spectrum pattern extractions. the feature selection module consists of a combinatorial selection algorithm where discriminatory patterns are extracted from among a large set of pattern attributes. these modules are wrapped around the classification modeler and solver into a machinelearning framework. the classification modeler and solver consist of novel optimization-based predictive models that maximize the correct classification while constraining the inter-group misclassifications. the classification/predictive models 1) have the ability to classify any number of distinct groups;2) allow incorporation of heterogeneous, and continuous/time-dependent types of attributes as input;3) utilize a high-dimensional data transformation that minimizes noise and errors in biological and clinical data;4) incorporate a reserved-judgement region that provides a safeguard against over-training;and 5) have successive multi-stage classification capability. Successful applications of our model to developing rules for gene silencing in cancer cells, predicting the immunity of vaccines, identifying the cognitive status of individuals, and predicting metabolite concentrations in humans will be discussed. We acknowledge our clinical/biological collaborators: Dr. Vertino (Winship Cancer Institute, Emory), Drs. Pulendran and Ahmed (Emory Vaccine Center), Dr. Levey (Neurodegenerative Disease and Alzheimer's Disease
A new functional model for burst firing in the dorsal thalamus is proposed where thalamocortical patternrecognition systems, based on kernel machine principles, are connected by burst signaling. the systems include i...
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A new functional model for burst firing in the dorsal thalamus is proposed where thalamocortical patternrecognition systems, based on kernel machine principles, are connected by burst signaling. the systems include input trapping in the dorsal thalamus, cortical learning state memory and processing in the thalamic reticular nucleus. Misclassified events are captured as training examples in the waking state and the patternrecognition systems are trained by extensive thalamic bursting in deep sleep.
Syntactic methods in patternrecognition have been used extensively in bioinformatics, and in particular, in the analysis of gene and protein expressions, and in the recognition and classification of biosequences, the...
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ISBN:
(纸本)9783642040306
Syntactic methods in patternrecognition have been used extensively in bioinformatics, and in particular, in the analysis of gene and protein expressions, and in the recognition and classification of biosequences, these methods are almost universally distance-based. this paper concerns the use of an Optimal and Information theoretic (OIT) probabilistic model [11] to achieve peptide classification using the information residing in their syntactic representations. the latter has traditionally been achieved using the edit distances required in the respective peptide comparisons. We advocate that, one can model the differences between compared strings as a mutation model consisting of random Substitutions, Insertions and Deletions (SID) obeying the OIT model. thus, in this paper, we show that the probability measure obtained. from the OIT model can be perceived as a sequence similarity metric, using which a Support Vector machine (SVM)-based peptide classifier, referred to as OIT-SVM, can be devised. the classifier, which we have built has been tested for eight different "substitution" matrices and for two different data sets, namely, the HIV-1 Protease Cleavage sites and the T-cell Epitopes. the results show that the OIT model performs significantly better than the one which uses a Needleman-Wunsch sequence alignment score, and the peptide classification methods that previously experimented withthe same two datasets.
Shape matching is one of the more significant research topics in the fields of computer vision, patternrecognition and machinelearning. Successful shape matching algorithms/ methods has a high potential for a wide v...
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Shape matching is one of the more significant research topics in the fields of computer vision, patternrecognition and machinelearning. Successful shape matching algorithms/ methods has a high potential for a wide variety of practical applications. In this paper, we present our effort on using linear projection methods for static hand sign recognition in Malaysian sign language. PCA and LPP methods have been used with a database of 240 hand shapes.
the proceedings contain 149 papers. the topics discussed include: rule based creative pattern generation for visual composition;date pre-processing issues: a case study for database marketing;SWDSS - hints to transfor...
ISBN:
(纸本)9789899624719
the proceedings contain 149 papers. the topics discussed include: rule based creative pattern generation for visual composition;date pre-processing issues: a case study for database marketing;SWDSS - hints to transform single system into a software product line;citizen participation in city planning and public decision assisted with ontologies and 3D semantics;classification of facial expressions using datamining and machinelearning algorithms;applying hidden Markov models to process mining;on the strengthening of OPENID authentication mechanisms withthe Portuguese citizen card;high quality video streaming over 3G+ mobile networks;a proposed unified communications platform based on open source technologies;and contribution to experimental performance evaluation of point-to-point links using WIMAX and Wi-Fi technologies.
Organisms exhibit a close structure-function relationship and a slight change in structure may in turn change their outputs accordingly [1]. this feature is important as it is the main reason why organisms have better...
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Tagging allows individuals to use whatever terms they think are appropriate to describe an item. Withthe growing popularity of tagging, more and more tags have been collected by a variety of applications. An item may...
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ISBN:
(纸本)9783642033537
Tagging allows individuals to use whatever terms they think are appropriate to describe an item. Withthe growing popularity of tagging, more and more tags have been collected by a variety of applications. An item may be associated with tags describing its different aspects, such as appearance, functionality, and location. However, little attention has been paid in the organization of tags;in most tagging systems, all the tags associated with an item are listed together regardless of their meanings. When the number of tags becomes large, finding useful information with regards to a certain aspect of an item becomes difficult. Improving the organization of tags in existing tagging systems is thus highly desired. In this paper, we propose a hierarchical approach to organize tags. In our approach, tags are placed into different categories based on their meanings. To find information with respect to a certain aspect of an item, one just needs to refer to its associated tags in the corresponding category. Since existing applications have already collected a large number of tags, manually categorizing all the tags is infeasible. We propose to use data-mining and machine-learning techniques to automatically and rapidly classify tags in tagging systems. A prototype of our approaches has been developed for a real-word tagging system.
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