To be able to optimise performance variables such as the rates of bed-occupancy, staff utilisation and the number of delayed or cancelled admissions in any healthcare units the rate at which patients are admitted to t...
详细信息
To be able to optimise performance variables such as the rates of bed-occupancy, staff utilisation and the number of delayed or cancelled admissions in any healthcare units the rate at which patients are admitted to that unit must be controlled. this paper proposes a method for evaluating admissions controlthat may subsequently be used as the basis for improving the control of admissions. the method is demonstrated through the presentation and discussion of results from an experimental study in a hospital environment comprising a suite of operating theatres, a post-operative recovery room and two intensive-care units. (c) 2004 Elsevier Ltd. All rights reserved.
Dynamic simulation of complex industrial systems is discussed, and a summary is presented of over a decade of work in the modelling, simulation and control of cryogenic separation and liquefaction processes. the work ...
详细信息
Dynamic simulation of complex industrial systems is discussed, and a summary is presented of over a decade of work in the modelling, simulation and control of cryogenic separation and liquefaction processes. the work includes not only successful applications but also the development of tools to facilitate the construction of the simulation flowsheets and their effective use in control system analysis and design. the use of these tools and of two commercial dynamic simulation packages is reviewed. the question of what is a required level of modelling detail in dynamic simulation applications is addressed. (C) 2000 ifac. Published by Elsevier Science Ltd. All rights reserved.
A computational modelling framework is presented which enables the simulation of cardiac electro-mechanics from the cellular level up to the whole organ level. At the cellular level this framework makes use of the rec...
详细信息
ISBN:
(纸本)0080441599
A computational modelling framework is presented which enables the simulation of cardiac electro-mechanics from the cellular level up to the whole organ level. At the cellular level this framework makes use of the recent development of CellML, an XML based markup language for the storage and exchange of biological models. the modelling framework is incorporated into CMISS, a Computational package that is used to define the tissue and organ level models as well as the numerical solution of the models implemented using this framework. Copyright (C) 2003 ifac.
We demonstrate that the methods of time series analysis supplied by Nonlinear Dynamics and by Symbolic Dynamics are applicable to sleep EEG-data analysis and may in future be used for computerized construction of hypn...
详细信息
ISBN:
(纸本)0080441599
We demonstrate that the methods of time series analysis supplied by Nonlinear Dynamics and by Symbolic Dynamics are applicable to sleep EEG-data analysis and may in future be used for computerized construction of hypnograms that are important tools in sleep disorder diagnosis.
Research in the area of automated cervical cytology has been prompted by the need to develop more efficient means of carrying out population screening programmes for cervical cancer, a disease responsible for the deat...
详细信息
ISBN:
(纸本)0080441599
Research in the area of automated cervical cytology has been prompted by the need to develop more efficient means of carrying out population screening programmes for cervical cancer, a disease responsible for the deaths of many women throughout the world annually. A historical survey of cytological image processing is given in this paper. the emphasis is placed on automated cervical cell processing under the fixed cell scan system.
Nerve cells communicate by generation and transmission of short electrical pulses (action potentials). A cascaded feedback control scheme consisting of an optimal controller (model predictive control, MPC) and a state...
详细信息
Nerve cells communicate by generation and transmission of short electrical pulses (action potentials). A cascaded feedback control scheme consisting of an optimal controller (model predictive control, MPC) and a state feedback controller to controlthe time-courses of the biophysical state variables underlying action potential generation was developed and evaluated in simulations. the control scheme was shown to provide new means for action potential generation, suppression of oscillations and blockage of action potential transmission. these new theoretical developments could represent a starting point for the design of new closed-loop electrical stimulation systems for patients suffering from different nerve system dysfunctions. (c) 2004 Elsevier Ltd. All rights reserved.
Characterising circulatory dysfunction and choosing a suitable treatment is often difficult and time consuming. this paper outlines a numerically stable minimal model of the human cardiovascular system (CVS) specifica...
详细信息
Characterising circulatory dysfunction and choosing a suitable treatment is often difficult and time consuming. this paper outlines a numerically stable minimal model of the human cardiovascular system (CVS) specifically aimed for rapid, on-site modelling to assist in diagnosis and treatment. A minimal number of governing equations and a realistic valve law are used to accurately capture trends in CVS dynamics. the model is shown to have long-term stability and consistency with non-specific initial conditions. Examples of model verification are shown for experimentally measured static and transient response data. the model is also verified to capture commonly seen changes in CVS function as a result of disease. these examples illustrate the power of the minimal model for capturing CVS dynamics in health and disease, while its simplicity enables its use as a clinical aid. (c) 2004 Elsevier Ltd. All rights reserved.
Gene therapy of cancer is the transfer of genetic material to correct genetic mutations in malignant cells or destroy cancer cells through cytolysis or other mechanisms. Intratumoural injection is often used for direc...
详细信息
ISBN:
(纸本)0080441599
Gene therapy of cancer is the transfer of genetic material to correct genetic mutations in malignant cells or destroy cancer cells through cytolysis or other mechanisms. Intratumoural injection is often used for direct delivery of viral particles (VP) into tumours. the temporal and spatial distributions of VP in the tissue of interest (TOI) following the injection may closely correlate withthe therapeutic results. thus, a theoretical model as a dispersion process is introduced to describe VP transport processes in the TOI. Which include mechanical flow, molecular diffusion, blood uptake, cellular absorption, and viral death and replication. Copyright (C) 2003 ifac.
暂无评论