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the benefits of using Guyton's model in a hypotensive control system

COMPUTER MEthODS AND PROGRAMS IN BIOMEDICINE 2008年第2期89卷 153-161页

作者： Nguyen, Chi-Ngon Simanski, Olaf Kaehler, Ralf Schubert, Agnes Janda, Matthias Bajorat, Joern Lampe, Bernhard Univ Rostock Dept Comp Sci & Elect Engn D-18119 Rostock Germany Cantho Univ Dept Telecommun & Control Engn Can Tho 92100 Vietnam Univ Rostock Clin Anesthesiol & Intens Care D-18055 Rostock Germany

In order to improve the intraoperative applications, this paper presents the advantages of using Guyton's model in hypotensive control system development. In this system, the mean arterial pressure is decreased and maintained at a low level during anaesthesia by controlling sodium nitroprusside infusion rate. the key of the study is to develop a physiological model of cardiovascular dynamics to present the mean arterial pressure response to sodium nitroprusside, which was considered as a linear model in most of known blood pressure control systems. Being linear, the previous models cannot accurately mimic a physiological system of human circulation, especially at deep hypotensive control with strong reaction of the body. the enhanced model in this study was modified based on Guyton's model of human circulation. It is useful to design a PID controller, which allows studying and handling the wide range of the body sensitivities. this model is also helpful for studying the behaviors of patients under anaesthesia conditions, such as the perfusion of organs and the reaction of the body at hypotensive state. A fuzzy gain scheduler and a supervising algorithm were also developed for online tuning the controller to handle the behavior of the body. the control system was tested on 25 experiments on seven pigs in the animal laboratory. Simulation and experiment results proved the usefulness of Guyton's model in control system design which can present the dynamical response of blood pressure in the circulation under and after hypotensive control. the results also indicated the safety and stability of the controller. (c) 2007 Elsevier Ireland Ltd. All rights reserved.

关键词： blood pressure fuzzy control physiological model medical systems medical applications

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Model-based respiratory motion correction using 3-D echocardiography

Model-based respiratory motion correction using 3-D echocard...

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5th IEEE International symposium on biomedical Imaging

作者： King, A. P. Jansen, C. Boubertakh, R. Rhode, K. S. Razavi, R. Penney, G. P. Kings Coll London Div Imaging Sci Interdisciplinary Med Imaging Grp London England

ISBN: (纸本)9781424420025

In this paper we investigate the use of 3-D echocardiography (echo) data for respiratory motion correction of MRI-derived roadmaps in image-guided interventions. By a combination of system calibration and tracking the MRI and echo coordinate systems are aligned. 3-D echo images at different respiratory positions are registered to an end-exhale 3-D echo image using a registration algorithm that uses a similarity measure based on local orientation and phase differences. We first assess the use of the echo-echo registration alone to perform motion-correction in the MRI coordinate system. Next, we investigate combining the echo-echo similarity measure with a MRI-derived motion model. Using experiments with cardiac MRI and 3-D echo data acquired from 2 volunteers, we demonstrate that significantly faster and more robust performance can be obtained using the motion model.

关键词： echocardiography respiratory motion modelling MRI

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An optimised multi-baseline approach for on-line MR-temperature monitoring on commodity graphics hardware

An optimised multi-baseline approach for on-line MR-temperat...

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5th IEEE International symposium on biomedical Imaging

作者： de Senneville, B. Denis Noe, K. O. Ries, M. Pedersen, M. Moonen, C. T. W. Sorensen, T. S. Univ Bordeaux 2 CNRS UMR 5231 IMF F-33076 Bordeaux France IUT Bordeaux 1 Bordeaux France Univ Aarhus Inst Clin Med MR Res Ctr Aarhus Denmark Univ Aarhus Dept Comp Sci Aarhus Denmark

ISBN: (纸本)9781424420025

Magnetic Resonance Imaging (MRI) can be used for non invasive temperature mapping and is therefore a promising tool to monitor and control interventional therapies based on thermal ablation. the Proton Resonance Frequency shift MRI technique gives an estimate of the temperature by comparing phase changes between dynamically acquired images. these temperature measurements are prone to motion induced errors however, particularly in abdominal organs due to breathing. Several computational approaches have been proposed previously to correct for these motion related errors on the measured temperature. they have required significant time to compute however, and have not been sufficiently fast for several real-time temperature mapping applications. this paper proposes to use modem graphics cards (GPUs) to assess on-line motion corrected thermal maps. the computation times obtained on the GPU are compared to an existing CPU reference implementation. An acceleration factor close to 7 was obtained for the processing of one slice (resolution 128 x 128 pixels), and higher than 21 for 12 slices, allowing a real-time implementation.

关键词： Magnetic Resonance Imaging real time systems temperature control image motion analysis motion compensation

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Study on the Coal Mine Personnel Position System Based on Wireless Body Sensor Networks

Study on the Coal Mine Personnel Position System Based on Wi...

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5th International Summer School and symposium on Medical Devices and Biosensors

作者： Wang Yan Zheng Ya-ru Ma Yong Liaoning Tech Univ Inst Elect & Control Engn Liaoning 125105 Huludao Peoples R China Liaoning Tech Univ Inst Sci Liaoning 125105 Huludao Peoples R China

ISBN: (纸本)9781424422524

In this paper, the wireless body sensor networks (WBSNs) technology is employed in coal mine personnel position system. With the use of this system, it was not able to only know where miners were but also know how healthy they were when an accident happened underground (for instance, a roof failing accident). With this information, the saviors can make the right salvation decision. the network model of WBSNs, the hardware designs of the body sensor node and the network optimize method are presented in this paper. In the case of satisfying coal mine application parameters and network connection parameters, genetic algorithm was used to optimize network parameters.

关键词： Personnel Wireless sensor networks Body sensor networks Temperature sensors biomedical monitoring Accidents Product safety Hardware Genetic algorithms Production systems

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Process of multi technical education in biomedical engineers curricula

Process of multi technical education in biomedical engineers...

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5th Int Conference on Information Technol and Applications in Biomedicine in Conjunction with the 2nd Int symposium and Summer School on biomedical and Health Engineering

作者： Penhaker, M. Cernohorsky, J. Sochorova, H. Cerny, M. Tech Univ Ostrava Fac Elect Engn & Comp Sci Dept Measurement & Control 17 Listopadu 15 Ostrava 70833 Czech Republic

ISBN: (纸本)9781424422548

biomedical engineering, clinical engineering and medical informatics represent interdisciplinary branches which are very progressive and acknowledged and which intervene into many spheres. the mentioned branches apply various technical principles and skills in biology and medicine: from proposals, construction and implementation, to the servicing of medical technology. these inspired to change the structure of curricula of the study branch and also the conception of some classes to better cover the legislative needs. Nowadays the study field biomedical engineering is educated as study fild in bachelor and master study at VSB - Technical university of Ostrava, Faculty of electrical engineering and computer science with cooperation of Medico-Social faculty of the University of Ostrava teaching medico - social courses. the courses are mainly provided in special laboratories which combines multi-technical proposition to solve during education in teams.

关键词： biomedical engineering

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the circadian cycle monitoring

The circadian cycle monitoring

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IEEE/EMBS International Summer School on Medical Devices and Biosensors

作者： M. Cerny M. Penhaker Biomedical EngineeringLaboratory Member Technical University of Ostrava Czech Republic Department of Measurement and Control Vice-director Technical University of Ostrava Ostrava Czech Republic

the HomeCare system is designed, developed and realized in our laboratory. It is remote monitoring system of base life functions which takes care about alone living elderly people. Not only standard monitored biosignals can give us the valuable information about the change in the state of the health of the monitored person. One of the possible monitored values can be the circadian cycle. the monitoring of the circadian cycles of elderly people in HomeCare systems is very usable. this work is focused on possibilities of the monitoring and the data processing of circadian cycles in frame of HomeCare systems which were designed for elderly people.

关键词： Circadian rhythm Remote monitoring Senior citizens biomedical monitoring Laboratories biomedical measurements System testing Computer science biomedical engineering Electric variables measurement

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Statistical colocalization in biological imaging with false discovery control

Statistical colocalization in biological imaging with false ...

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IEEE International symposium on biomedical Imaging

作者： B. Zhang N. Chenouard J.-C. Olivo-Marin V. Meas-Yedid Unite Analyse dImages Quantitative Institut Pasteur Paris France

In this paper, we present a novel object-based statistical colocalization method. Our colocalization relies on multiple hypothesis tests on the distances between all pairs of the (spot-shaped) objects from the two markers. We wish to test among all these pairs how many are significantly close to each other such that they cannot occur just "by chance". Two objects are decided to be co-localized if the test on their distance is significant. For this purpose, we first extract the objects by applying a wavelet-based spot detection approach which fully takes into account the mixed-Poisson-Gaussian noise process of confocal fluorescence images. then, we build a null hypothesis model in which the distribution of the distance between two independently randomly drawn detections in the cell is estimated by a kernel method. the observed distances are tested against this null model. Our tests control the false discovery rate (FDR) of the co-localizations. Simulations show that this approach has a good specificity. Furthermore, our method has been successfully applied in a real problem of protein colocalization analysis during the endocytic process.

关键词： Biological control systems Proteins Testing Pixel Crops Object detection Fluorescence Kernel Biological system modeling Biological cells

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Modeling and analysis of energy harvesting nodes in body sensor networks

Modeling and analysis of energy harvesting nodes in body sen...

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IEEE/EMBS International Summer School on Medical Devices and Biosensors

作者： Alireza Seyedi Biplab Sikdar Department of Electrical and Computer Engineering University of Rochester Rochester NY USA Department of Electrical Computer and Systems Engineering Rensselaer Polytechnic Institute Troy NY USA

A Markov based unified model for an energy harvesting node in a body sensor network is presented. Using the presented model, the probability of event loss due to energy run out is calculated. the results provide insight into the performance of energy harvesting nodes in a body sensor network as well as design requirements for such devices.

关键词： Body sensor networks biomedical monitoring Batteries Traffic control Medical services Costs Measurement Biosensors Probability Joining processes

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Visualizing morphogenesis and growth by temporal interpolation of surface-based 3D atlases

Visualizing morphogenesis and growth by temporal interpolati...

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IEEE International symposium on biomedical Imaging

作者： Chavdar Papazov Vincent J. Dercksen Hans Lamecker Hans-Christian Hege Zuse Institute Berlin Berlin Germany

Image-based 3D atlases have been proven to be very useful in biological and medical research. they serve as spatial reference systems that enable researchers to integrate experimental data in a spatially coherent way and thus to relate diverse data from different experiments. Typically such atlases consist of tissue-separating surfaces. the next step are 4D atlases that provide insight into temporal development and spatio- temporal relationships. Such atlases are based on time series of 3D images and related 3D models. We present work on temporal interpolation between such 3D atlases. Due to the morphogenesis of tissues during biological development, the topology of the non-manifold surfaces may vary between subsequent time steps. For animation therefore a smooth morphing between non-manifold surfaces with different topology is needed.

关键词： Interpolation Surface reconstruction Image reconstruction Biological system modeling Topology Image segmentation Shape control Anatomy Data visualization Cells (biology)

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A healthcare monitoring system with wireless woven inductor channels for body sensor network

A healthcare monitoring system with wireless woven inductor ...

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IEEE/EMBS International Summer School on Medical Devices and Biosensors

作者： Seulki Lee Jerald Yoo Hoi-Jun Yoo Department of EECS KAIST Semiconductor System Laboratory Daejeon South Korea Korea Advanced Institute of Science and Technology Daejeon Daejeon KR

A healthcare monitoring system with wireless woven inductor channels is proposed for body sensor networks. A sensor node with the proposed woven inductor channel consumes only 300 uW for sensing and 340 uW for communication with 1 Mbps data rate. the personal sensor controller consumes 8 mW, and the efficiency is 178 times than the previous work.

关键词： Medical services Wireless sensor networks Inductors Body sensor networks Wearable sensors Sensor systems Communication system control Batteries biomedical monitoring Laboratories

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