this paper investigates the use of a total least squares approach in a generalization of the iterative closest point (ICP) algorithm for shape registration. A new Generalized Total Least Squares (GTLS) formulation of ...
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In this paper, we present a physics-based deformable model framework for the quantification of shape and motion parameters of the Left Anterior Descending (LAD) coronary artery in the heart's local frame of refere...
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Partial volume effects are present in nearly all medical imaging data. these artifacts blur the boundaries between different regions, making accurate delineation of anatomical structures difficult. In this paper, we p...
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this work involves the conception of the experimental dosimetric testing setup of an image based procedure for intravascular brachytherapy by 192Ir seed in peripheral arteries. After making sure of the suitability of ...
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this paper presents a novel segmentation approach featuring shape constraints of multiple structures. A framework is developed combining statistical shape modeling with a maximum a posteriori segmentation problem. the...
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this paper extends our prior work on multi-modal image registration based on the a priori knowledge of the joint intensity distribution that we expect to obtain, and Kullback-Leibler distance. this expected joint dist...
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A new method for fully automated segmentation of white matter lesions (WMLs) on cranial MR imaging is presented. the algorithm uses five types of regular MRI-scans. It is based on a K-Nearest Neighbor (KNN) classifica...
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A new method for fully automated segmentation of white matter lesions (WMLs) on cranial MR imaging is presented. the algorithm uses five types of regular MRI-scans. It is based on a K-Nearest Neighbor (KNN) classification technique, which builds a feature space from voxel intensity features and spatial information. the technique generates images representing the probability per voxel being part of a WML. By application of thresholds on these probability maps binary segmentations can be produced. ROC-curves show that the segmentations achieve a high sensitivity and specificity. three similarity measures, the similarity index (SI), the overlap fraction (OF) and the extra fraction (EF), are calculated for evaluation of the results and determination of the optimal threshold on the probability map. Investigation of the relation between the total lesion volume and the similarity measures shows that the method performs well for lesions larger than 2 cc. the maximum SI per patient is correlated to the total WML volume. No significant relation between the lesion volume and the optimal threshold has been observed. the probabilistic equivalents of the SI, OF en EF (PSI, POF and PEF) allow direct evaluation of the probability maps, which provides a strong tool for comparison of different classification results. A significant correlation between the lesion volume and the PSI and the PEF has been noticed. this method for automated WML segmentation is applicable to lesions of different sizes and shapes, and reaches an accuracy that is comparable to existing methods for multiple sclerosis lesion segmentation. Furthermore, it is suitable for detection of WMLs in large and longitudinal population studies. (C) 2004 Elsevier B.V. All rights reserved.
the MicroTactus is a family of instruments that we have designed to detect signals arising from the interaction of a tip with soft or hard objects and to magnify them for haptic and auditory reproduction. We construct...
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Osteoporosis is due to the following two phenomena: a reduction bone mass and a degradation of the microarchitecture of bone tissue. In this paper, we propose a method for extracting morphological information enabling...
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this paper describes a method for generating unfolded views of the stomach based on 3-D gray image deformation. Unfolded views can show the status of the stomach in one image. the previous method approximates the shap...
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