the proceedings contain 29 papers. the topics discussed include: a new framework for co-clustering of gene expression data;biclustering of expression microarray data using affinity propagation;a two-way Bayesianmixtur...
ISBN:
(纸本)9783642248542
the proceedings contain 29 papers. the topics discussed include: a new framework for co-clustering of gene expression data;biclustering of expression microarray data using affinity propagation;a two-way Bayesianmixture model for clustering in metagenomics;new gene subset selection approaches based on linear separating genes and gene-pairs;identification of biomarkers for prostate cancer prognosis using a novel two-step cluster analysis;renal cancer cell classification using generative embeddings and information theoretic kernels;integration of epigenetic data in Bayesian network modeling of gene regulatory network;metabolic pathway inference from time series data: a non iterative approach;highlighting metabolic strategies using network analysis over strain optimization results;and wrapper- and ensemble-based feature subset selection methods for biomarker discovery in targeted metabolomics.
the proceedings contain 55 papers. the special focus in this conference is on patternrecognition and Machine Intelligence. the topics include: Recent Advances in Recommender Systems and Future Directions;On the Numbe...
the proceedings contain 55 papers. the special focus in this conference is on patternrecognition and Machine Intelligence. the topics include: Recent Advances in Recommender Systems and Future Directions;On the Number of Rules and Conditions in Mining Data with Attribute-Concept Values and "Do Not Care" Conditions;Simplifying Contextual Structures;Towards a Robust Scale Invariant Feature Correspondence;Hierarchical Agglomerative Method for Improving NPS;A New Linear Discriminant Analysis Method to Address the Over-Reducing Problem;Procedural Generation of Adjustable Terrain for Application in Computer Games Using 2D Maps;Fixed Point Learning Based 3D Conversion of 2D Videos;Fast and Accurate Foreground Background Separation for Video Surveillance;Enumeration of Shortest Isothetic Paths Inside a Digital Object;Modified Exemplar-Based Image Inpainting via Primal-Dual Optimization;A Novel Approach for Image Super Resolution Using Kernel Methods;Generation of Random Triangular Digital Curves Using Combinatorial Techniques;Tackling Curse of Dimensionality for Efficient Content Based Image Retrieval;Face Profile View Retrieval Using Time of Flight Camera Image Analysis;Context-Based Semantic Tagging of Multimedia Data;Improved Simulation of Holography Based on Stereoscopy and Face Tracking;Head Pose Tracking from RGBD Sensor Based on Direct Motion Estimation;A Novel Hybrid CNN-AIS Visual patternrecognition Engine;Modified Orthogonal Neighborhood Preserving Projection for Face recognition;An Optimal Greedy Approximate Nearest Neighbor Method in Statistical patternrecognition.
this book constitutes the refereed proceedings of the 7thinternationalconference on patternrecognition in bioinformatics, prib 2012, held in Tokyo, Japan, in November 2012. the 24 revised full papers presented were...
ISBN:
(数字)9783642341236
ISBN:
(纸本)9783642341229
this book constitutes the refereed proceedings of the 7thinternationalconference on patternrecognition in bioinformatics, prib 2012, held in Tokyo, Japan, in November 2012. the 24 revised full papers presented were carefully reviewed and selected from 33 submissions. their topics are widely ranging from fundamental techniques, sequence analysis to biological network analysis. the papers are organized in topical sections on generic methods, visualization, image analysis, and platforms, applications of patternrecognition techniques, protein structure and docking, complex data analysis, and sequence analysis.
In recent years, several methods for gene networks (GNs) inference from expression data have been developed. Also, models of data integration (as protein-protein and protein-DNA) are nowadays broadly used to face the ...
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ISBN:
(纸本)9783319091921;9783319091914
In recent years, several methods for gene networks (GNs) inference from expression data have been developed. Also, models of data integration (as protein-protein and protein-DNA) are nowadays broadly used to face the problem of few amount of expression data. Moreover, it is well known that biological networks conserve some topological properties. the small-world topology is a common arrangement in nature found both in biological and non-biological phenomena. However, in general this information is not used by GNs inference methods. In this work we proposed a new GNs inference algorithm that combines topological features and expression data. the algorithm outperforms the approach that uses only expression data both in accuracy and measures of recovered network.
In this paper, four methods were explored for improving the performance of ***'s structure drawing algorithm when dealing with large sequences;First, the approximation based Barnes-Hut algorithm was explored. Seco...
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ISBN:
(纸本)9783642341236
In this paper, four methods were explored for improving the performance of ***'s structure drawing algorithm when dealing with large sequences;First, the approximation based Barnes-Hut algorithm was explored. Second, the effects of using multithreading were measured. additionally, dynamic C libraries, which integrate C code into the Java (TM) environment, were investigated. Finally, a technique termed structure recall was examined. the results demonstrated that the use of the Barnes-Hut algorithm produced the most drastic improvements in run-time, but distorts the structure if too crude of an approximation is used. Multithreading and integration of C code proved to be favorable approaches since these improved the speed at which calculations are done, without distorting the structures.
G protein coupled receptors (GPCRs) are one of the most prominent and abundant family of membrane proteins in the human genome. Since they are main targets of many drugs, GPCR research has grown significantly in recen...
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ISBN:
(纸本)9783642341236
G protein coupled receptors (GPCRs) are one of the most prominent and abundant family of membrane proteins in the human genome. Since they are main targets of many drugs, GPCR research has grown significantly in recent years. However the fact that only few structures of GPCRs are known still remains as an important challenge. therefore, the classification of GPCRs is a significant problem provoked from increasing gap between orphan GPCR sequences and a small amount of annotated ones. this work employs motif distillation using defined parameters, distinguishing power evaluation method and general weighted set cover problem in order to determine the minimum set of motifs which can cover a particular GPCR subfamily. Our results indicate that in Family A Peptide subfamily, 91% of all proteins listed in GPCRdb can be covered by using only 691 different motifs, which can be employed later as an invaluable source for developing a third level GPCR classification tool.
A basic task in protein analysis is to discover a set of sequence patterns that characterizes the function of a protein family. To address this task, we introduce a synthesized pattern representation called Aligned Pa...
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ISBN:
(纸本)9783642341236
A basic task in protein analysis is to discover a set of sequence patterns that characterizes the function of a protein family. To address this task, we introduce a synthesized pattern representation called Aligned pattern (AP) Cluster to discover potential functional segments in protein sequences. We apply our algorithm to identify and display the binding segments for the Cytochrome C. and Ubiquitin protein families. the resulting AP Clusters correspond to protein binding segments that surround the binding residues. When compared to the results from the protein annotation databases, PROSITE and pFam, ours are more efficient in computation and comprehensive in quality. the significance of the AP Cluster is that it is able to capture subtle variations of the binding segments in protein families. It thus could help to reduce time-consuming simulations and experimentation in the protein analysis.
this book constitutes the refereed proceedings of the 6thinternationalconference on patternrecognition in bioinformatics, prib 2011, held in Delft, the Netherlands, in November 2011. the 29 revised full papers pres...
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ISBN:
(数字)9783642248559
ISBN:
(纸本)9783642248542
this book constitutes the refereed proceedings of the 6thinternationalconference on patternrecognition in bioinformatics, prib 2011, held in Delft, the Netherlands, in November 2011. the 29 revised full papers presented were carefully reviewed and selected from 35 submissions. the papers cover the wide range of possible applications of bioinformatics in patternrecognition: novel algorithms to handle traditional patternrecognition problems such as (bi)clustering, classification and feature selection; applications of (novel) patternrecognition techniques to infer and analyze biological networks and studies on specific problems such as biological image analysis and the relation between sequence and structure. they are organized in the following topical sections: clustering, biomarker selection and classification, network inference and analysis, image analysis, and sequence, structure, and interactions.
the information theory has been used for quite some time in the area of computational biology. In this paper we discuss and improve the function Entropic Profile, introduced by Vinga and Almeida in [23]. the Entropic ...
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