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A Software Framework for the Analysis of Complex Microscopy Image data

IEEE TRANSACTIONS ON INFORMATION technology IN BIOMEDICINE 2010年第4期14卷 1075-1087页

作者： Chao, Jerry Ward, E. Sally Ober, Raimund J. Univ Texas Dallas Dept Elect Engn Richardson TX 75080 USA Univ Texas SW Med Ctr Dallas Dept Immunol Dallas TX 75390 USA

Technological advances in both hardware and software have made possible the realization of sophisticated biological imaging experiments using the optical microscope. As a result, modern microscopy experiments are capable of producing complex image datasets. For a given data analysis task, the images in a set are arranged, based on the requirements of the task, by attributes such as the time and focus levels at which they were acquired. Importantly, different tasks performed over the course of an analysis are often facilitated by the use of different arrangements of the images. We present a software framework that supports the use of different logical image arrangements to analyze a physical set of images. This framework, called the Microscopy Image Analysis Tool (MIATool), realizes the logical arrangements using arrays of pointers to the images, thereby removing the need to replicate and manipulate the actual images in their storage medium. In order that they may be tailored to the specific requirements of disparate analysis tasks, these logical arrangements may differ in size and dimensionality, with no restrictions placed on the number of dimensions and the meaning of each dimension. MIATool additionally supports processing flexibility, extensible image processing capabilities, and data storage management.

关键词： Image analysis image viewer microscopy multidimensional data software framework

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Performance Evaluation of Iterative Channel Codes for Digital data storage on Microfilm

Performance Evaluation of Iterative Channel Codes for Digita...

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IEEE Global Telecommunications Conference (GLOBECOM 2010)

作者： Pflug, Florian Voges, Christoph Fingscheidt, Tim Tech Univ Carolo Wilhelmina Braunschweig Inst Commun Technol D-38106 Braunschweig Germany

ISBN: (纸本)9781424456383

In the past few years microfilm has gained new research interest as a medium for long-term storage of digital data. This became particularly possible by recent advances in laser film recording technology. In contrast to other optical or magnetic storage media, the microfilm digital channel (MDC) still has been subject to characterization in only a few publications. In this paper we investigate iterative channel codes for the MDC, in particular low-density parity-check and turbo convolutional codes. Simulation results show that practically error-free storage can be achieved with code rates even above 0.85 on a monochrome MDC with binary amplitude-shift keying modulation.

关键词： amplitude shift keying binary amplitude-shift keying modulation binary codes convolutional codes digital data storage iterative channel codes iterative decoding laser film recording low density parity check code magnetic storage magnetic storage media mic

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Mid-infrared optical parametric amplifier using silicon nanophotonic waveguides

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NATURE PHOTONICS 2010年第8期4卷 557-560页

作者： Liu, Xiaoping Osgood, Richard M., Jr. Vlasov, Yurii A. Green, William M. J. Columbia Univ Dept Elect Engn New York NY 10027 USA IBM Corp Thomas J Watson Res Ctr Yorktown Hts NY 10598 USA

All-optical signal processing is an approach used to dramatically decrease power consumption and speed up the performance of next-generation optical telecommunications networks(1-3). Nonlinear optical effects such as four-wave mixing and parametric gain have been explored to realize all-optical functions in glass fibres(4). An alternative approach is to use nanoscale engineering of silicon waveguides to enhance optical nonlinearities by up to five orders of magnitude(5), enabling integrated chip-scale all-optical signal processing. Four-wave mixing within silicon nanophotonic waveguides has been used to demonstrate telecom-band (lambda approximate to 1,550 nm) all-optical functions including wavelength conversion(6-9), signal regeneration(10) and tunable optical delay(11). Despite these important advances, strong two-photon absorption(12) of the telecom-band pump presents a fundamental obstacle, limiting parametric gain to values of several decibels(13). Here, we demonstrate a silicon nanophotonic optical parametric amplifier exhibiting broadband gain as high as 25.4 dB, using a mid-infrared pump near one-half the bandgap energy (E approximate to 0.55 eV, lambda approximate to 2,200 nm), where parasitic two-photon absorption-related absorption vanishes(12,14,15). This gain is high enough to compensate all insertion losses, resulting in 13-dB net off-chip amplification, using only an ultra-compact 4-mm silicon chip. Furthermore, engineering of higher-order waveguide dispersion(16) can potentially enable mid-infrared-pumped silicon parametric oscillators(17-19) and amplifiers for telecom-band optical signals.

关键词： nature photonics Nature Photonics nature publishing group content journal optoelectronics optics biophotonics quantum optics cryptography spectroscopy terahertz technology light propagation lasers LEDs photovotaics fibre optics optical data storage

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Monolithically integrated solid-state terahertz transceivers

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NATURE PHOTONICS 2010年第8期4卷 565-569页

作者： Wanke, Michael C. Young, Erik W. Nordquist, Christopher D. Cich, Michael J. Grine, Albert D. Fuller, Charles T. Reno, John L. Lee, Mark Sandia Natl Labs Albuquerque NM 87185 USA LMATA Govt Serv Albuquerque NM USA

Recent advances in microfabricated terahertz quantum cascade lasers have achieved coherent power and frequency performance previously possible only with much larger gas- or vacuum-tube sources. A significant advantage offered by terahertz quantum cascade lasers lies in the potential to integrate them with other components on the same chip. Such terahertz photonic integrated circuits would help close the terahertz technology gap between microwave electronics and infrared photonics. Here, we describe the first successful monolithic integration of a terahertz quantum cascade laser and diode mixer to form a simple but generically useful terahertz photonic integrated circuit-a microelectronic terahertz transceiver. We show that this terahertz photonic integrated circuit performs all the basic functions (for example, transmission of a coherent carrier, heterodyne reception of an external signal, frequency locking and tuning) of discrete-component terahertz photonic systems, but at a small fraction of the size and in a robust platform scalable to semiconductor fabrication production.

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Highly power-efficient quantum cascade lasers

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NATURE PHOTONICS 2010年第2期4卷 95-98页

作者： Liu, Peter Q. Hoffman, Anthony J. Escarra, Matthew D. Franz, Kale J. Khurgin, Jacob B. Dikmelik, Yamac Wang, Xiaojun Fan, Jen-Yu Gmachl, Claire F. Princeton Univ Dept Elect Engn Princeton NJ 08544 USA Johns Hopkins Univ Dept Elect & Comp Engn Baltimore MD 21218 USA AdTech Opt Inc City Of Industry CA 91748 USA

Quantum cascade lasers1 are promising mid-infrared semiconductor light sources for molecular detection in applications such as environmental sensing or medical diagnostics. For such applications, researchers have been striving to improve device performance(2). Recently, improvements in wall plug efficiency have been pursued with a view to realizing compact, portable, power-efficient and high-power quantum cascade laser systems(3,4). However, advances have largely been incremental, and the basic quantum design has remained unchanged for many years, with the wall plug efficiency yet to reach above 35%. A crucial factor in quantum cascade laser performance is the efficient transport of electrons into the laser active regions. We recently theoretically described this transport process as limited by the interface-roughness-induced detuning of resonant tunnelling(5). Here, we report that an 'ultrastrong coupling' design strategy overcomes this limiting factor and leads to the experimental realization of quantum cascade lasers with 40-50% wall plug efficiency when operated in pulsed mode at temperatures of 160 K or lower.

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Performance Evaluation of Iterative Channel Codes for Digital data storage on Microfilm

Performance Evaluation of Iterative Channel Codes for Digita...

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2010 IEEE Global Telecommunications Conference GLOBECOM 2010

作者： Florian Pflug Christoph Voges Tim Fingscheidt Institute of Communications Technology Technische Universitäat Braunschweig Brunswick Germany

关键词： Parity check codes Bit error rate Decoding Demodulation Convolutional codes Channel models

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Multiplexing holograms for data page storage using a LCD as a hybrid ternary modulation

Multiplexing holograms for data page storage using a LCD as ...

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Conference on Holography - advances and Modern Trends

作者： Fernandez, Elena Ortuno, Manuel Gallego, Sergi Garcia, Celia Marquez, Andres Belendez, Augusto Pascual, Inmaculada Univ Alicante Dep Opt Farmacol & Anat Apartado 99 E-03080 Alicante Spain Univ Alicante Dept Fis Ing Sist & Senal E-03080 Alicante Spain

ISBN: (纸本)9780819476326

Holographic data storage is a new optical technology which allows an important number of bits to be stored in a recording material. In this work, holographic data pages were stored in a PVA/acrylamide photopolymer layer using a peristrophic multiplexing method. This material is formed of acrylamide photopolymers, which are considered interesting materials for recording holographic memories. A liquid crystal (LCD) device was used to modify the object beam and store the data pages in the material. This LCD was used to modulate the object beam in order to reduce the zero frequency of the Fourier Transform (FT) of the object. The scheme used to reduce this frequency was hybrid ternary modulation (HTM).

关键词： Photopolymers Holographic recording materials Liquid crystal device Hybrid ternary modulation

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Parallel data processing based on high density volume holographic correlator

Parallel data processing based on high density volume hologr...

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Photonic Fiber and Crystal Devices: advances in Materials and Innovations in Device Applications III

作者： Cao, Liangcai He, Qingsheng Ma, Qiang Jin, Guofan State Key Laboratory of Precision Measurement Technology and Instruments Department of Precision Instruments Tsinghua University Beijing 100084 China

ISBN: (纸本)9780819477101

Because of the high density and high parallelism of the volume holographic storage, volume holographic correlator can be used as parallel multiple pattern filters. It has a natural feature for the parallel optical computing. However, the applications of this kind of correlator are limited due to low accuracy of the computing results and small number of parallel channels. To improve the data processing accuracy, some methods are proposed and employed to reduce the noise and computing error of the volume holographic correlator. The sidelobes of the correlation pattern can be totally suppressed. The shapes of the correlation patterns are made uniform. And the detected intensity can approach the inner products of the input images and the stored images. The computing speed of the correlator based on the current optoelectronic elements could be nearly two or three magnitude orders over the computing speed of traditional electronic processors. The applications of volume holographic correlator in the star field identification are demonstrated. © 2009 SPIE.

关键词： optical data processing

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CASSIE: Contextual Analysis for Spectral and Spatial Information Extraction

CASSIE: Contextual Analysis for Spectral and Spatial Informa...

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Signal Processing, Sensor Fusion, and Target Recognition XVIII

作者： Gibson, Laurie Horne, James Haverkamp, Donna SAIC 801 Main Street Louisville CO 80027 United States

ISBN: (纸本)9780819476029

advances in understanding the biology of vision show that humans use not only bottom-up, feature-based information in visual analysis, but also top-down contextual information. To reflect this method of processing, we developed a technology called CASSIE for Science Applications International Corporation (SAIC) that uses low-level image features and contextual cues to determine the likelihood that a certain target will be found in a given area. CASSIE is a tool by which information from various data layers can be probabilistically combined to determine spatialand informational context within and across different types of data. It is built on a spatial foundation consisting of a twodimensional hexagonal, hierarchical grid structure for data storage and access. This same structure facilitates very fastcomputation of information throughout the hierarchy for all data layers, as well as fast propagation of probabilisticinformation derived from those layers. Our research with CASSIE investigates the effectiveness of generated probability maps to reflect a human interpretation, potential benefits in terms of accuracy and processing speed for subsequent target detection, and methods forincorporating feedback from target detection algorithms to apply additional contextual constraints (for example, allowable or expected target groupings). We discuss further developments such as learning in CASSIE and how to incorporate additional data modalities. © 2009 SPIE.

关键词： Digital storage

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Intelligent real-time CCD data processing system based on variable frame rate

Intelligent real-time CCD data processing system based on va...

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International Symposium on Photoelectronic Detection and Imaging 2009: advances in Imaging Detectors and Applications

作者： Chen, Su-Ting College of Electronic and Information Engineering Nanjing University of Information Science and Technology Nanjing 210044 China

ISBN: (纸本)9780819476654

In order to meet the need of image shooting with CCD in unmanned aerial vehicles, a real-time high resolution CCD data processing system based on variable frame rate is designed. The system is consisted of three modules: CCD control module, data processing module and data display module. In the CCD control module, real-time flight parameters (e.g. flight height, velocity and longitude) should be received from GPS through UART (Universal Asynchronous Receiver Transmitter) and according to the corresponding flight parameters, the variable frame rate is calculated. Based on the calculated variable frame rate, CCD external synchronization control impulse signal is generated in the control of FPGA and then CCD data is read out. In the data processing module, data segmentation is designed to extract ROI (region of interest), whose resolution is equal to valid data resolution of HDTV standard conforming to SMPTE (1080i). On one hand, Ping-pong SRAM storage controller is designed in FPGA to real-time store ROI data. On the other hand, according to the need of intelligent observing, changeable window position is designed, and a flexible area of interest is obtained. In the real-time display module, a special video encoder is used to accomplish data format conversion. data after storage is packeted to HDTV format by creating corresponding format information in FPGA. Through inner register configuration, high definition video analog signal is implemented. The entire system has been implemented in FPGA and validated. It has been used in various real-time CCD data processing situations. © 2009 SPIE.

关键词： Field programmable gate arrays (FPGA)

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