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检索条件"任意字段=Conference on SPIE Image-Guided Procedures, Robotic Interventions, and Modeling"

共 167 条记录，以下是91-100 订阅

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Rapid Virtual Stenting for Intracranial Aneurysms

Rapid Virtual Stenting for Intracranial Aneurysms

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conference on spie image-guided procedures, robotic interventions, and modeling

作者： Zhao, Liang Chen, Danyang Chen, Zihe Wang, Xiangyu Paliwal, Nikhil Xiang, Jianping Meng, Hui Corso, Jason J. Xu, Jinhui Univ Buffalo Buffalo NY 14260 USA Univ Michigan Ann Arbor MI 48109 USA

ISBN: (纸本)9781510600218

The rupture of Intracranial Aneurysms is the most severe form of stroke with high rates of mortality and disability. One of its primary treatments is to use stent or Flow Diverter to divert the blood flow away from the IA in a minimal invasive manner. To optimize such treatments, it is desirable to provide an automatic tool for virtual stenting before its actual implantation. In this paper, we propose a novel method, called ball-sweeping, for rapid virtual stenting. Our method sweeps a maximum inscribed sphere through the aneurysmal region of the vessel and directly generates a stent surface touching the vessel wall without needing to iteratively grow a deformable stent surface. Our resulting stent mesh has guaranteed smoothness and variable pore density to achieve an enhanced occlusion performance. Comparing to existing methods, our technique is computationally much more efficient.

关键词： Surface plasmons Finite element methods Computer programming Computer simulations Arteries Medical imaging robotics Vascular diseases Visual process modeling Visualization

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Evaluation of a μCT-based electro-anatomical cochlear implant model

Evaluation of a μCT-based electro-anatomical cochlear impla...

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conference on spie image-guided procedures, robotic interventions, and modeling

作者： Cakir, Ahmet Dawant, Benoit M. Noble, Jack. H. Vanderbilt Univ Dept Elect Engn & Comp Sci Nashville TN 37235 USA

ISBN: (纸本)9781510600218

Cochlear implants (CIs) are considered standard treatment for patients who experience sensory-based hearing loss. Although these devices have been remarkably successful at restoring hearing, it is rare to achieve natural fidelity, and many patients experience poor outcomes. Previous studies have shown that outcomes can be improved when optimizing CI processor settings using an estimation of the CI's neural activation patterns found by detecting the distance between the CI electrodes and the nerves they stimulate in pre- and post-implantation CT images. We call this method image-guided CI Programming (IGCIP). More comprehensive electro-anatomical models (EAMs) might better estimate neural activation patterns than using a distance-based estimate, potentially leading to selecting further optimized CI settings. Our goal in this study is to investigate whether mu CT-based EAMs can accurately estimate neural stimulation patterns. For this purpose, we have constructed EAMs of N=9 specimens. We analyzed the sensitivity of our model to design parameters such as field-of-view, resolution, and tissue resistivity. Our results show that our model is stable to parameter changes. To evaluate the utility of patient-specific modeling, we quantify the difference in estimated neural activation patterns across specimens for identically located electrodes. The average computed coefficient of variation (COV) across specimens is 0.186, suggesting patient-specific models are necessary and that the accuracy of a generic model would be insufficient. Our results suggest that development of in vivo patient-specific EAMs could lead to better methods for selecting CI settings, which would ultimately lead to better hearing outcomes with CIs.

关键词： Cochlear implant modeling image-guided cochlear implant programming

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Diaphragm motion characterization using chest motion data for biomechanics-based lung tumor tracking during EBRT

Diaphragm motion characterization using chest motion data fo...

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conference on spie image-guided procedures, robotic interventions, and modeling

作者： Karami, Elham Gaede, Stewart Lee, Ting-Yim Samani, Abbas Univ Western Ontario Dept Med Biophys London ON Canada Robarts Res Inst Imaging Res Labs London ON Canada London Reg Canc Program Dept Phys & Engn London ON Canada Univ Western Ontario Dept Oncol London ON Canada Lawson Hlth Res Inst Imaging Program London ON Canada Univ Western Ontario Dept Med Imaging London ON Canada Univ Western Ontario Dept Elect & Comp Engn London ON Canada Univ Western Ontario Biomed Engn Grad Program London ON Canada

ISBN: (纸本)9781510600218

Despite recent advances in image-guided interventions, lung cancer External Beam Radiation Therapy (EBRT) is still very challenging due to respiration induced tumor motion. Among various proposed methods of tumor motion compensation, real-time tumor tracking is known to be one of the most effective solutions as it allows for maximum normal tissue sparing, less overall radiation exposure and a shorter treatment session. As such, we propose a biomechanics-based real-time tumor tracking method for effective lung cancer radiotherapy. In the proposed algorithm, the required boundary conditions for the lung Finite Element model, including diaphragm motion, are obtained using the chest surface motion as a surrogate signal. The primary objective of this paper is to demonstrate the feasibility of developing a function which is capable of inputting the chest surface motion data and outputting the diaphragm motion in real-time. For this purpose, after quantifying the diaphragm motion with a Principal Component Analysis (PCA) model, correlation coefficient between the model parameters of diaphragm motion and chest motion data was obtained through Partial Least Squares Regression (PLSR). Preliminary results obtained in this study indicate that the PCA coefficients representing the diaphragm motion can be obtained through chest surface motion tracking with high accuracy.

关键词： lung cancer EBRT tumor motion tracking biomechanical modeling PCA extrinsic marker

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image-guided preoperative prediction of pyramidal tract side effect in deep brain stimulation

Image-guided preoperative prediction of pyramidal tract side...

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conference on spie image-guided procedures, robotic interventions, and modeling

作者： Baumgarten, C. Zhao, Y. Sauleau, P. Malrain, C. Jannin, P. Haegelen, C. INSERM UMR 1099 Rennes France Univ Rennes 1 LTSI Rennes France Univ Hosp Rennes Dept Neurol Rennes France Univ Hosp Rennes Dept Neurosurg Rennes France

ISBN: (纸本)9781510600218

Deep brain stimulation of the medial globus pallidus is a surgical procedure for treating patients suffering from Parkinson's disease. Its therapeutic effect may be limited by the presence of pyramidal tract side effect (PTSE). PTSE is a contraction time-locked to the stimulation when the current spreading reaches the motor fibers of the pyramidal tract within the internal capsule. The lack of side-effect predictive model leads the neurologist to secure an optimal electrode placement by iterating clinical testing on an awake patient during the surgical procedure. The objective of the study was to propose a preoperative predictive model of PTSE. A machine learning based method called PyMAN (for Pyramidal tract side effect Model based on Artificial Neural network) that accounted for the current of the stimulation, the 3D electrode coordinates and the angle of the trajectory, was designed to predict the occurrence of PTSE. Ten patients implanted in the medial globus pallidus have been tested by a clinician to create a labeled dataset of the stimulation parameters that trigger PTSE. The kappa index value between the data predicted by PyMAN and the labeled data was .78. Further evaluation studies are desirable to confirm whether PyMAN could be a reliable tool for assisting the surgeon to prevent PTSE during the preoperative planning.

关键词： Artificial neural network Computer-assisted surgery Computational modeling Deep brain stimulation Parkinson's disease Patient-specific model Pyramidal tract side effect

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Automatic Pose Correction for image-guided Nonhuman Primate Brain Surgery Planning

Automatic Pose Correction for Image-Guided Nonhuman Primate ...

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conference on spie image-guided procedures, robotic interventions, and modeling

作者： Ghafurian, Soheil Chen, Antong Hines, Catherine Dogdas, Belma Bone, Ashleigh Lodge, Kenneth OMalley, Stacey Winkelmann, Christopher T. Bagchi, Ansuman Lubbers, Laura S. Uslaner, Jason M. Johnson, Colena Renger, John Zariwala, Hatim A. Merck Res Labs Informat IT Appl Math & Modeling West Point PA 19486 USA Rutgers State Univ Dept Ind & Syst Engn New Brunswick NJ 08901 USA Merck Res Labs Translat Imaging Biomarkers West Point PA 19486 USA Merck Res Labs Appl Math & Modeling Informat IT Rahway NJ 07065 USA Merck Res Labs Safety Assessment & Lab Anim Resources West Point PA 19486 USA Pfizer Comparat Med La Jolla CA 92121 USA Merck Res Labs Pharmacol West Point PA 19486 USA

ISBN: (纸本)9781510600218

Intracranial delivery of recombinant DNA and neurochemical analysis in nonhuman primate (NHP) requires precise targeting of various brain structures via imaging derived coordinates in stereotactic surgeries. To attain targeting precision, the surgical planning needs to be done on preoperative three dimensional (3D) CT and/or MR images, in which the animals head is fixed in a pose identical to the pose during the stereotactic surgery. The matching of the image to the pose in the stereotactic frame can be done manually by detecting key anatomical landmarks on the 3D MR and CT images such as ear canal and ear bar zero position. This is not only time intensive but also prone to error due to the varying initial poses in the images which affects both the landmark detection and rotation estimation. We have introduced a fast, reproducible, and semi-automatic method to detect the stereotactic coordinate system in the image and correct the pose. The method begins with a rigid registration of the subject images to an atlas and proceeds to detect the anatomical landmarks through a sequence of optimization, deformable and multimodal registration algorithms. The results showed similar precision (maximum difference of 1.71 in average in-plane rotation) to a manual pose correction.

关键词： stereotactic surgery MRI atlas rigid nonrigid registration deep brain targeting mid-sagittal plane

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Optimal atlas construction through hierarchical image registration

Optimal atlas construction through hierarchical image regist...

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conference on spie image-guided procedures, robotic interventions, and modeling

作者： Grevera, George J. Udupa, Jayaram K. Odhner, Dewey Torigian, Drew A. St Josephs Univ Dept Comp Sci 5600 City Ave Philadelphia PA 19131 USA Hosp Univ Penn Dept Radiol Med Image Proc Grp MIPG 3400 Spruce St Philadelphia PA 19104 USA

ISBN: (纸本)9781510600218

Atlases (digital or otherwise) are common in medicine. However, there is no standard framework for creating them from medical images. One traditional approach is to pick a representative subject and then proceed to label structures/regions of interest in this image. Another is to create a "mean" or average subject. Atlases may also contain more than a single representative (e.g., the Visible Human contains both a male and a female data set). Other criteria besides gender may be used as well, and the atlas may contain many examples for a given criterion. In this work, we propose that atlases be created in an optimal manner using a well-established graph theoretic approach using a min spanning tree (or more generally, a collection of them). The resulting atlases may contain many examples for a given criterion. In fact, our framework allows for the addition of new subjects to the atlas to allow it to evolve over time. Furthermore, one can apply segmentation methods to the graph (e.g., graph-cut, fuzzy connectedness, or cluster analysis) which allow it to be separated into "sub-atlases" as it evolves. We demonstrate our method by applying it to 50 3D CT data sets of the chest region, and by comparing it to a number of traditional methods using measures such as Mean Squared Difference, Mattes Mutual Information, and Correlation, and for rigid registration. Our results demonstrate that optimal atlases can be constructed in this manner and outperform other methods of construction using freely available software.

关键词： digital atlas modeling anatomical models

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Structure Sensor for mobile markerless augmented reality

Structure Sensor for mobile markerless augmented reality

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conference on spie image-guided procedures, robotic interventions, and modeling

作者： Kilgus, T. Bux, R. Franz, A. M. Johnen, W. Heim, E. Fangerau, M. Mueller, M. Yen, K. Maier-Hein, L. German Canc Res Ctr Comp Assisted Intervent Heidelberg Germany Inst Forens Med & Traff Med Heidelberg Germany German Canc Res Ctr Div Med Phys Radiat Oncol Heidelberg Germany German Canc Res Ctr Div Med & Biol Informat Heidelberg Germany

ISBN: (纸本)9781510600218

3D Visualization of anatomical data is an integral part of diagnostics and treatment in many medical disciplines, such as radiology, surgery and forensic medicine. To enable intuitive interaction with the data, we recently proposed a new concept for on-patient visualization of medical data which involves rendering of subsurface structures on a mobile display that can be moved along the human body. The data fusion is achieved with a range imaging device attached to the display. The range data is used to register static 3D medical imaging data with the patient body based on a surface matching algorithm. However, our previous prototype was based on the Microsoft Kinect camera and thus required a cable connection to acquire color and depth data. The contribution of this paper is two-fold. Firstly, we replace the Kinect with the Structure Sensor - a novel cable free range imaging device-to improve handling and user experience and show that the resulting accuracy (target registration error: 4.8 +/- 1.5 mm) is comparable to that achieved with the Kinect. Secondly, a new approach to visualizing complex 3D anatomy based on this device, as well as 3D printed models of anatomical surfaces, is presented. We demonstrate that our concept can be applied to in vivo data and to a 3D printed skull of a forensic case. Our new device is the next step towards clinical integration and shows that the concept cannot only be applied during autopsy but also for presentation of forensic data to laypeople in court or medical education.

关键词： 3D modeling Sensors Visualization Augmented reality Prototyping Cameras Skull 3D acquisition Forensic science 3D visualizations

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image-guided Intracranial Cannula Placement for Awake In Vivo Microdialysis in Nonhuman Primates

Image-guided Intracranial Cannula Placement for Awake <i>In ...

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conference on spie image-guided procedures, robotic interventions, and modeling

作者： Chen, Antong Bone, Ashleigh Hines, Catherine D. G. Dogdas, Belma Montgomery, Tamara O. Michener, Maria Winkelmann, Christopher T. Ghafurian, Soheil Lubbers, Laura S. Renger, John Bagchi, Ansuman Uslaner, Jason M. Johnson, Colena Zariwala, Hatim A. Merck Res Labs Appl Math & Modeling West Point PA 19486 USA Merck Res Labs Safety Assessment & Lab Anim Resources West Point PA 19486 USA Merck Res Labs Translat Imaging Biomarkers West Point PA 19486 USA Merck Res Labs Appl Math & Modeling Rahway NJ 07065 USA Pfizer Comparat Med La Jolla CA 92121 USA Rutgers State Univ Dept Ind & Syst Engn New Brunswick NJ 08901 USA Merck Res Labs Pharmacol West Point PA 19486 USA

ISBN: (纸本)9781510600218

Intracranial microdialysis is used for sampling neurochemicals and large peptides along with their metabolites from the interstitial fluid (ISF) of the brain. The ability to perform this in nonhuman primates (NHP) e.g., rhesus could improve the prediction of pharmacokinetic (PK) and pharmacodynamics (PD) action of drugs in human. However, microdialysis in rhesus brains is not as routinely performed as in rodents. One challenge is that the precise intracranial probe placement in NHP brains is difficult due to the richness of the anatomical structure and the variability of the size and shape of brains across animals. Also, a repeatable and reproducible ISF sampling from the same animal is highly desirable when combined with cognitive behaviors or other longitudinal study end points. Toward that end, we have developed a semi-automatic flexible neurosurgical method employing MR and CT imaging to (a) derive coordinates for permanent guide cannula placement in mid-brain structures and (b) fabricate a customized recording chamber to implant above the skull for enclosing and safeguarding access to the cannula for repeated experiments. In order to place the intracranial guide cannula in each subject, the entry points in the skull and the depth in the brain were derived using co-registered images acquired from MR and CT scans. The anterior/posterior (A/P) and medial-lateral (M/L) rotation in the pose of the animal was corrected in the 3D image to appropriately represent the pose used in the stereotactic frame. An array of implanted fiducial markers was used to transform stereotactic coordinates to the images. The recording chamber was custom fabricated using computer-aided design (CAD), such that it would fit the contours of the individual skull with minimum error. The chamber also helped in guiding the cannula through the entry points down a trajectory into the depth of the brain. We have validated our method in four animals and our results indicate average placement error o

关键词： psychiatry neurodegeneration stereotactic surgery non-human primates translation model

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Progress in Biomedical Optics and Imaging - Proceedings of spie

Progress in Biomedical Optics and Imaging - Proceedings of S...

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Medical Imaging 2016: image-guided procedures, robotic interventions, and modeling

ISBN: (纸本)9781510600218

The proceedings contain 99 papers. The topics discussed include: fast generation of digitally reconstructed radiograph through an efficient preprocessing of ray attenuation values;automatic detection of a hand-held needle in ultrasound via phased-based analysis of the tremor motion;automatic masking for robust 3D-2D image registration in image-guided spine surgery;real-time self-calibration of a tracked augmented reality display;robust patella motion tracking using intensity-based 2D-3D registration on dynamic bi-plane fluoroscopy: towards quantitative assessment in MPFL reconstruction surgery;MIND demons for MR-to-CT deformable image registration in image-guided spine surgery;accurate biopsy-needle depth estimation in limited-angle tomography using multi-view geometry;automatic geometric rectification for patient registration in image-guided spinal surgery;clinical workflow for spinal curvature measurement with portable ultrasound;classification of prostate cancer grade using temporal ultrasound: in vivo feasibility study;ultrasound to video registration using a bi-plane transrectal probe with photoacoustic markers;and deformable registration of x-ray to MRI for post-implant dosimetry in prostate brachytherapy.

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image Guidance Improves Localization of Sonographically Occult Colorectal Liver Metastases

Image Guidance Improves Localization of Sonographically Occu...

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conference on Medical Imaging - image-guided procedures, robotic interventions, and modeling

作者： Leung, Universe Simpson, Amber L. Adams, Lauryn B. Jarnagin, William R. Miga, Michael I. Kingham, T. Peter Mem Sloan Kettering Canc Ctr Dept Surg New York NY 10021 USA Vanderbilt Univ Dept Biomed Engn Nashville TN 37235 USA

ISBN: (纸本)9781628415056

Assessing the therapeutic benefit of surgical navigation systems is a challenging problem in image-guided surgery. The exact clinical indications for patients that may benefit from these systems is not always clear, particularly for abdominal surgery where image-guidance systems have failed to take hold in the same way as orthopedic and neurosurgical applications. We report interim analysis of a prospective clinical trial for localizing small colorectal liver metastases using the Explorer system (Pathfinder Technologies, Nashville, TN). Colorectal liver metastases are small lesions that can be difficult to identify with conventional intraoperative ultrasound due to echogeneity changes in the liver as a result of chemotherapy and other preoperative treatments. Interim analysis with eighteen patients shows that 9 of 15 (60%) of these occult lesions could be detected with image guidance. image guidance changed intraoperative management in 3 (17%) cases. These results suggest that image guidance is a promising tool for localization of small occult liver metastases and that the indications for image-guided surgery are expanding.

关键词： Liver Tumors Surgery image-guided intervention Ultrasonography 3D modeling Colorectal cancer Cancer Clinical trials Liver cancer

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