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Use of patient specific 3D printed (3DP) neurovascular phantoms for mechanical assessment of devices used in image guided minimally invasive procedures

Use of patient specific 3D printed (3DP) neurovascular phant...

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conference on Medical Imaging - Imaging Informatics for Healthcare, Research, and Applications

作者： Tabaczynski, Janelle R. Stoll, Thomas Shepard, Lauren Siddiqui, Mohamed I. G. Karkhanis, Nitant V. Sommer, Kelsey Siddiqui, Adnan H. Ionita, Ciprian N. SUNY Buffalo Dept Biomed Engn Buffalo NY 14228 USA SUNY Buffalo Toshiba Canon Stroke & Vasc Res Ctr Buffalo NY 14208 USA SUNY Buffalo Jacobs Sch Med Neurosurg Buffalo NY 14208 USA

ISBN: (数字)9781510616486

ISBN: (纸本)9781510616486

Purpose: Patient-specific 3D printed phantoms (3DP) can reproduce accurate patient geometry and provide precise tools for Endovascular image guided interventions (EIGI) simulations. We propose to build and test 3DP phantoms which mimic the arterial wall elasticity and surface properties and demonstrate their utility in comprehensive EIGI simulations. Materials and Methods: 3DP idealized and patient specific vascular phantoms were manufactured using Stratasys Objet 500 Connex 3. The idealized phantoms were created using a sine wave shape, patient specific phantoms were based on CT-angiography volumes. The phantoms were coated with a hydrophilic material to mimic vascular surface properties. We tested various endovascular procedures using an Interventional Device Testing Equipment (IDTE) 2000 and measured push/pull force used to actuate endovascular devices during EIGIs. Results: The force needed to advance devices in neurovascular phantoms varied based on tortuosity, material and coating, ranging from -3 to 21 grams-force. Hydrophilic coating reduced maximum force from 21 to 4.8 grams-force in the same model. IDTE 2000 results of neurovascular models were compared to hand manipulation of guidewire access using a six-axis force sensor with forces ranging from -50 to 440 grams. The clot retriever tested in carotid models experienced most friction around tortuous bends ranging from -65 to -90 grams-force, with increasing rigidity of materials creating increased friction. Sine wave model forces varied from -2 to 105 grams. Conclusions: 3DP allows manufacturing of vascular phantoms with precise mechanical and surface properties which can be used for EIGI simulations for imaging protocol optimization and device behavior assessment.

关键词： 3D modeling Instrument modeling Fluoroscopy Manufacturing Sensors 3D printing Coating image segmentation 3D image processing X-rays

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Evaluation of the effect of partial asymmetric stent coverage on neurovascular aneurysm hemodynamics using computer fluid dynamics (CFD) calculations

Evaluation of the effect of partial asymmetric stent coverag...

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Medical Imaging 2007 conference

作者： Kim, Minsuok Rangwala, Hussain S. Ionita, Ciprian Hoffmann, Kenneth R. Taulbee, Dale B. Meng, Hui Rudin, Stephen SUNY Buffalo Toshiba Stroke Res Ctr Amherst NY 14214 USA SUNY Buffalo Deta Mech & Aerosp Engn Amherst NY 14214 USA SUNY Buffalo Dept Neurosurg Amherst NY 14214 USA SUNY Buffalo Dept Radiol Amherst NY 14214 USA SUNY Buffalo Dept Biophys & Physiol Amherst NY 14214 USA

ISBN: (纸本)9780819466273

The asymmetric vascular stent (AVS) is a new minimally invasive endovascular device, designed to reduce the potential for further growth and rupture of cerebral aneurysms by substantially modifying the aneurysmal inflow. The low porosity part of the AVS or patch must be deployed to either completely or partially cover the aneurysm orifice. In this study, we investigated the effect on aneurysm hemodynamics of partial coverage with an asymmetric stent using Computational Fluid Dynamics (CFD) analysis and visualization. The low porosity patch of an asymmetric stent was computationally created and deformed to fit into the vessel lumen. Such a patch was placed both in an idealized aneurysm model and in a patient-specific aneurysm model to cover only a portion of the aneurysm orifice either proximally or distally according to the flow direction. The CFD-generated hemodynamic image sequences in the untreated and stented aneurysm models were compared. The asymmetric stent effectively attenuated the aneurysmal flow when the primary inflow was blocked by the patch. Consequently, the Wall Shear Stress (WSS) was reduced, and flow stasis was substantially increased by stenting. For the idealized model, distal placement was better for reducing the inflow jet, whereas for the patient-specific model proximal placement was better. We can conclude that CFD visualizations may be essential to guide either the optimal positioning of a small low porosity region of the AVS or the acceptability of inaccurate placement of a larger AVS patch for partial aneurysm orifice coverage.

关键词： computational fluid dynamics image-based biomechanical models vascular biomechanics and modeling stems for aneurysms image guided interventions

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Initial investigations of a special high-definition (Hi-Def) zoom capability in a new detector system for neuro-interventional procedures

Initial investigations of a special high-definition (Hi-Def)...

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conference on Medical Imaging - Physics of Medical Imaging

作者： Nagesh, S. V. Setlur Shankar, A. Krebs, J. Hinaman, J. Bednarek, D. R. Rudin, S. SUNY Buffalo Toshiba Stroke & Vasc Res Ctr Buffalo NY 14260 USA

ISBN: (数字)9781510616363

ISBN: (纸本)9781510616363

Real-time visualization of fine details ranging to 100 um or less in neuro-vascular imaging guided interventions is important. A separate high-resolution detector mounted on a standard flat panel detector (FPD) was previously reported. This device had to be rotated mechanically into position over the FPD for high resolution imaging. Now, the new detector reported here has a high definition (Hi-Def) zoom capability along with the FPD built into one unified housing. The new detector enables rapid switching, by the operator between Hi-Def and FPD modes. Standard physical metrics comparing the new Hi-Def modes with those of the FPD are reported, demonstrating improved imaging resolution and noise capability at patient doses similar to those used for the FPD. Semi-quantitative subjective studies involving qualitative clinician feedback on images of interventional devices such as a Pipeline Embolization Device (PED) acquired in both Hi-Def and FPD modes are presented. The PED is deployed in a patient specific 3D printed neuro-vascular phantom embedded inside realistic bone and with tissue attenuating material. Field-of-view (FOV), exposure and magnification were kept constant for FPD and Hi-Def modes. Static image comparisons of the same view of the PED within the phantom were rated by expert interventionalists who chose from the following ratings: Similar, Better, or Superior. Generally, the Hi-Def zoomed images were much preferred over the FPD, indicating the potential to improve endovascular procedures and hence outcomes using such a Hi-Def feature.

关键词： Sensors image resolution Skull 3D modeling Modulation transfer functions Tissues Visualization Zoom lenses Signal attenuation X-rays

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Exciting Progress in the Growth of JMI

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JOURNAL OF MEDICAL IMAGING 2014年第2期1卷 020101页

作者： Giger, Maryellen L. The Univ. of Chicago (United States)

Welcome to the second issue of the spie Journal of Medical Imaging (JMI). As of this writing, we have received 146 submissions from 28 countries—from major institutions worldwide. I believe we are on track in accomplishing our goals for the journal as the manuscripts submitted thus far span the various fields of medical imaging. For example, this second issue includes excellent papers on image processing; computer-aided diagnosis; image-guided procedures, robotic interventions and modeling; image perception, observer performance, and technology; ultrasonic imaging and tomography; digital pathology; and biomedical applications in molecular, structural, and functional imaging. We also publish our first book review.

关键词： Medical imaging Biomedical optics Digital image processing Functional imaging image processing Pathology Performance modeling robotics Tomography Ultrasonography

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Design Optimization for Accurate Flow Simulations in 3D Printed Vascular Phantoms Derived from Computed Tomography Angiography

Design Optimization for Accurate Flow Simulations in 3D Prin...

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conference on Medical Imaging - Imaging Informatics for Healthcare, Research, and Applications

作者： Sommer, Kelsey Izzo, Richard L. Shepard, Lauren Podgorsak, Alexander R. Rudin, Stephen Siddiqui, Adnan H. Wilson, Michael F. Angel, Erin Said, Zaid Springer, Michael Ionita, Ciprian N. Univ Buffalo Dept Biomed Engn Buffalo NY 14228 USA Univ Buffalo Toshiba Stroke & Vasc Res Ctr Buffalo NY 14208 USA Jacobs Inst Buffalo NY 14208 USA Univ Buffalo Jacobs Sch Med Univ Buffalo Neurosurg Buffalo NY 14208 USA Univ Buffalo Jacobs Sch Med Univ Buffalo Cardiol Buffalo NY 14208 USA Toshiba Amer Med Syst Irvine CA 92618 USA

ISBN: (纸本)9781510607217;9781510607224

3D printing has been used to create complex arterial phantoms to advance device testing and physiological condition evaluation. Stereolithographic (STL) files of patient-specific cardiovascular anatomy are acquired to build cardiac vasculature through advanced mesh-manipulation techniques. Management of distal branches in the arterial tree is important to make such phantoms practicable. We investigated methods to manage the distal arterial flow resistance and pressure thus creating physiologically and geometrically accurate phantoms that can be used for simulationsof image-guided interventional procedures with new devices. Patient specific CT data were imported into a Vital Imaging workstation, segmented, and exported as STL files. Using a mesh-manipulation program (Meshmixer) we created flow models of the coronary tree. Distal arteries were connected to a compliance chamber. The phantom was then printed using a Stratasys Connex3 multimaterial printer: the vessel in TangoPlus and the fluid flow simulation chamber in Vero. The model was connected to a programmable pump and pressure sensors measured flow characteristics through the phantoms. Physiological flow simulations for patient-specific vasculature were done for six cardiac models (three different vasculatures comparing two new designs). For the coronary phantom we obtained physiologically relevant waves which oscillated between 80 and 120 mmHg and a flow rate of similar to 125 ml/min, within the literature reported values. The pressure wave was similar with those acquired in human patients. Thus we demonstrated that 3D printed phantoms can be used not only to reproduce the correct patient anatomy for device testing in image-guided interventions, but also for physiological simulations. This has great potential to advance treatment assessment and diagnosis.

关键词： 3D modeling Arteries 3D printing Computer aided design Computed tomography Sensors image segmentation Resistance 3D acquisition Printing Angiography Computer simulations Imaging informatics

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Design and modeling of a Parallel Robot for Ultrasound guided Percutaneous Needle interventions

Design and Modeling of a Parallel Robot for Ultrasound Guide...

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Annual conference of the IEEE Industrial Electronics Society

作者： Sabri Orcun ORHAN Mehmet Can YILDIRIM Ozkan BEBEK Mechanical Engineering Ozyegin University Istanbul Turkey

ISBN: (纸本)9781479917631

Necessity of precise positioning in percutaneous needle operations enables robotic systems to take part in medical procedures. Researches that have been done until today showed robotic systems increase the accuracy of medical interventions. This paper presents the design and modeling of a 5DOF parallel robot that will be used in Ultrasound image guided percutaneous needle interventions. In order to design the robot, workspace and torque analysis were conducted. System identification was performed on robot to understand the system dynamics. System calibration was performed with optical tracking system to increase the accuracy of the system. Gravity compensation and friction modeling were conducted on the robot. Using gravity compensation and friction models, a torque computed controller was implemented to system.

关键词： Parallel robots modeling Robot Ultrasonic Waves friction force model NEEDLES precise registration medical procedure Torque System identification Intervention

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Latest Advancement in Medical Surgery using Artificial Intelligence

Latest Advancement in Medical Surgery using Artificial Intel...

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Artificial Intelligence and Quantum Computation-Based Sensor Application (ICAIQSA), International conference on

作者： Priyanka Anup Ujjainkar Shital A. Raut Computer Science and Engineering Visvesvaraya National Institute of Technology Nagpur Maharashtra

ISBN: (数字)9798331517953

ISBN: (纸本)9798331517960

Recent advancements in artificial intelligence (AI) have significantly enhanced the use of computer vision, machine learning, natural language processing, augmented reality, and deep learning in surgical video analysis. Laparoscopic procedures generate vast amounts of video data, presenting opportunities for AI to support real-time decision-making and improve surgeon training. AI-based computer vision techniques can extract valuable insights from these videos, facilitating precise intraoperative decisions and enhancing educational systems. Key applications of AI in surgery include robotic surgery, image- guided interventions, and instrument tracking. Emerging fields like automatic surgical action prediction and tool identification are gaining prominence, aiming to refine real-time support systems. The integration of multiple computer vision models, such as Dinov2 and the latest YOLOv9, with balanced classes, holds the potential to address existing challenges in the accuracy and real-time identification of instruments and organs. Future research should focus on further developing these AI applications and utilizing them for more effective surgical training and skill evaluation.

关键词： Training Laparoscopes Computer vision Computational modeling Instruments Decision making Surgery Streaming media Real-time systems Artificial intelligence

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