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检索条件"任意字段=Conference on Smart Biomedical and Physiological Sensor Technology XI"

共 154 条记录，以下是41-50 订阅

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Salicylic Acid (SA) detection using bi-enzyme microfluidic electrochemical sensor 15

Salicylic Acid (SA) detection using bi-enzyme microfluidic e...

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conference on smart biomedical and physiological sensor technology XV

作者： Kashyap, Bhuwan Kumar, Ratnesh Iowa State Univ Dept Elect & Comp Engn Ames IA 50010 USA

ISBN: (数字)9781510618367

ISBN: (纸本)9781510618367

Salicylic Acid (SA) is a phyto-hormone involved in the regulation of induced plant defense mechanisms, primarily against biotic stresses. Various methods have been reported for detecting SA. The electrochemical methods offer economical, portable, and accurate concentration measurement of bio-chemicals like SA. Electrochemical biosensors often require modification of the working electrode (WE) with specific materials to functionalize it with bio-molecules, needed for target analyte recognition. The proposed biosensor provides a unique methodology of selectively coating the inter-digital electrodes (IDE) and further applying the method to develop a biosensor to detect SA. The electrodes are fabricated using a novel deposition process termed as, Capillary action assisted deposition (CAAD) which consists of IDEs fabricated in the form of small finger-like channels connected to a wider main channel. The drop-casted sample automatically flows from the main channel into the fine fingers under the effect of capillary action. The sensor includes a 3-electrode system arranged in a 3-D geometry, forming an integrated microfluidic channel for analyte solution flow. The WE is selectively coated with, first, Graphene oxide (GO) and next, the bi-enzyme Salicylate Hydroxylase (SH) and Tyrosinase (TYR) recipe using the proposed CAAD process. The bi-enzyme exhibits selectivity towards SA and the proposed sensor shows the detection range of 0.5 mu m to 64 mu m. The electrochemical reactions are characterized by Chrono-amperometry (CA) and shows the sensitivity of 34.4 mu A cm(-2) per decade change in SA concentration (in mu m). To the best of our knowledge, the proposed bi-enzyme system in a microfluidic device for SA sensing is the first of its kind.7

关键词： Salicylic acid Phyto-hormone Electrochemical bi-enzyme microfluidic capillary action

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Bio-Sensing Textile for Medical Monitoring Applications

Bio-Sensing Textile for Medical Monitoring Applications

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3rd International conference on smart Materials, Structures and Systems

作者： Luprano, Jean Ctr Suisse Elect & Microtech SA CH-2002 Neuchatel Switzerland

ISBN: (纸本)9783908158233

The commercial systems using intelligent textiles that start to appear on the market perform physiological measurements such as body temperature, electrocardiogram, respiration rate, etc. and target sport and healthcare applications. Biochemical measurements of body fluids combined with available health monitoring technology will extend these systems by addressing important health and safety issues. BIOTEX, standing for Bio-sensing Textile for Health Management, is a European project, which aims at developing dedicated biochemical sensing techniques that can be integrated into textiles. Such a system would be a major breakthrough for personalized healthcare and would allow for the first time the monitoring of body fluids with sensors distributed in a textile substrate. The potential applications include isolated people, convalescents and patients with chronic diseases, sports performance assessment and training. The project is addressing several challenges, among which: sweat collection and delivery to the sensors, high sensitivity with a wearable system, wearability issues, sensor calibration and lack of research in sweat analysis.

关键词： bio-sensing wearable biosensor smart clothes smart textile SFIT

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Preliminary Study on Multi-sensors Wearable smart Shoes using the Internet of Things Techniques 7

Preliminary Study on Multi-sensors Wearable Smart Shoes usin...

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IEEE 7th Global conference on Consumer Electronics (GCCE)

作者： Lee, Chao-Hsien Gen, Mao-Qun Natl Taipei Univ Technol Dept Elect Engn Taipei Taiwan

ISBN: (纸本)9781538663097

Daily exercise leads to better health. Hence, a lot of people keep running or walking habits. Thus, how to become successful runners without injuries is one urgent research issue. This paper shows one wearable smart shoes equipped with several types of sensors for long-term exercise monitoring. Not only the gait status but also the ground surface conditions, e. g., wet or rugged, and physiological signals, e. g., EMG, can be collected and analyzed simultaneously by the proposed smart shoes. Based on our experimental results, the proposed multi-sensor wearable smart shoes can have more than 80% accuracy in average.

关键词： Footwear Intelligent sensors Electromyography Foot biomedical monitoring Muscles

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Topographic imaging of an absorbing object in a tissue-like scattering medium using a single source-detector pair 15

Topographic imaging of an absorbing object in a tissue-like ...

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15th conference on smart biomedical and physiological sensor technology held at SPIE Defense + Commercial Sensing conference

作者： Mertiri, M. Raptis, N. Fragkos, M. A. Roditi, E. Syvridis, D. Univ Athens Dept Informat & Telecommun Univ Campus Athens 15784 Greece Eulambia Adv Technol Ltd 24 Agiou Ioannou St Athens 15342 Greece Univ Athens Dept Phys Univ Campus Athens 15784 Greece

ISBN: (数字)9781510627062

ISBN: (纸本)9781510627055;9781510627062

Diffuse optical tomography is an emerging biomedical imaging technique, due to its numerous advantages, such as low cost and non-ionizing radiation. In this work, we have developed a very simple setup, which included a single source - photodiode (SP) pair for scanning a sample of water with diluted Intralipid, simulating a biological tissue. LEDs emitting at 470, 525 and 624 nm, as well as a 650 nm Fabry Perot laser, were used as light sources. Scattered light from the sample was detected by the photodiode placed next to the LED. The SP distance could vary and the phantom could be scanned by moving the SP pair in precise, small and automated steps without any intervention during the measurements. Therefore, we obtained measurements from multiple locations on the sample, with just one SP pair. The presented experimental system verified the feasibility of deploying extremely low cost devices for detection and imaging absorbing objects of 1 cm height, placed inside a scattering medium. Maximum depth detection was 2.5 cm. As expected, the quality of the obtained images was degrading, as the object's depth or the scanning step was increasing. Additionally, we developed Monte Carlo simulations of the setup, which achieved good agreement with the experimental results. We also conducted another set of simulations, studying the depth sensitivity of a single static SP pair considering a scattering medium similar to the experimental phantom with and without object. We observed that the depth sensitivity increases as the source wavelength increases from 450 nm to 650 nm.

关键词： Diffuse optic topography biomedical optical imaging Monte Carlo simulation

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Non-Contact Vital Sign Monitoring With a Metamaterial Surface

Non-Contact Vital Sign Monitoring With a Metamaterial Surfac...

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IEEE MTT-S International Microwave biomedical conference (IMBioC)

作者： Nguyen, Dat T. Zeng, Qihang Tian, xi Ho, John S. Natl Univ Singapore NUS Grad Sch Integrat Sci & Engn Program Singapore Singapore Natl Univ Singapore Dept Elect & Comp Engn Singapore Singapore Natl Univ Singapore SIA NUS Digital Aviat Corp Lab Singapore Singapore

ISBN: (纸本)9781665423397

Vital sign monitoring is important for determining the health status and well-being of an individual. Despite their high level of accuracy, clinical sensing methods for vital signs, such as heart or respiration signals, often require direct skin contact and the use of wires, making them restrictive and inconvenient. In contrast, alternative sensing approaches using wireless means can be comfortable for users and are suitable for long-term, continuous health monitoring scenarios. Recent advances in physiological sensing using Doppler radars present great potential for non-contact vital sign monitoring, but face many challenges due to background clutter and large body motions. In this work, we develop an integrated system for non-contact vital sign monitoring based on microwave metamaterials and software-defined Doppler radar. Our sensor is thin, flexible, and able to monitor health through clothing. We demonstrate our system's capability in respiration and cardiac sensing through experiments on a healthy volunteer and validate its cardiac sensing accuracy against electrocardiography as the gold standard. Validation results show a Pearson's correlation coefficient r approximate to 0.9 and Bland-Altman agreement limits of +/- 37.1 ms between our sensor's and the gold standard's estimation of heart beat-to-beat intervals.

关键词： biological radar physiological sensing spoof surface plasmons vital sign monitoring

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Utilizing Metalized Fabrics for Liquid and Rip Detection and Localization

Utilizing Metalized Fabrics for Liquid and Rip Detection and...

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conference on smart biomedical and physiological sensor technology X

作者： Holland, Stephen A. Mahan, Cody A. Kuhn, Michael J. Rowe, Nathan C. Univ Tennessee 1520 Middle Dr Knoxville TN 37916 USA Western Kentucky Univ Bowling Green KY 42101 USA Oak Ridge Natl Lab Oak Ridge TN 37830 USA

ISBN: (纸本)9780819495105

This paper proposes a novel technique for utilizing electrically conductive textiles as a distributed sensor for detecting and localizing liquids (e. g., blood), damage (e. g., rips, cuts, bullet holes) and, potentially, biosignals. The proposed technique is verified through both simulation and experimental measurements. Circuit theory is employed to depict conductive fabric as a bounded, near-infinite grid of resistors. Solutions to the well-known infinite resistance grid problem are used to confirm the accuracy and validity of this modeling approach. Simulations allow for discontinuities to be placed within the resistor matrix to illustrate the effects of bullet holes within the fabric. A real-time experimental system was developed that uses a multiplexed, Wheatstone bridge measurement approach to determine the resistances of a coarse electrode grid across the conductive fabric. Non-uniform resistance values of the grid infer the presence of liquids and rips in the fabric. The resistor-grid model is validated through a comparison of simulated and experimental results. Results suggest accuracy proportional to the electrode spacing in determining the presence and location of disturbances in conductive fabric samples. Future work is focused on refining the experimental system to provide more accuracy in detecting and localizing events (although just the knowledge of a penetration may be adequate for some intended applications) as well as developing a complete prototype that can be deployed for field testing. Potential applications include intelligent clothing, flexible, lightweight sensing systems, and combat wound detection.

关键词： Conductive textile distributed sensor resistance grid penetration flexible combat wound detection

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sensor enhanced microfluidic devices for cell based assays and organs on chip 12

Sensor enhanced microfluidic devices for cell based assays a...

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conference on smart biomedical and physiological sensor technology xiI

作者： Gaertner, Claudia Ungerboeck, Birgit Schulz, Ingo Jahn, Tobias Mosig, Alexander Mayr, Torsten Becker, Holger Microfluid ChipShop GmbH D-07747 Jena Germany Jena Univ Hosp Inst Biochem 2 D-07743 Jena Germany Graz Univ Technol Inst Analyt Chem & Food Chem A-8010 Graz Austria

ISBN: (纸本)9781628416039

Cell-based assays and organ-like substrates gather increasing attention due to their potentials in diagnostic and drug development. The use of these cell-based systems will allow to better understand in-vivo processes and to test for the direct influence of different substances on cell viability or metabolic activity e.g. in drug development and in addition to identify the influence of generated metabolites or different cell types. In this paper we present a respective technical platform, which enables the use of such cell-based assays. The platform is based on a microfluidic cell-assay toolbox, designed in a fashion allowing to minimize manual steps for cell culture on chip. Elements being essential for this work include membrane elements integrated into a microfluidic device for the separation of liquid stream together with a targeted supply of reagents and a three dimensional feeding of embedded cells. The influence of the metabolism from one cell type on the other can be evaluated due to the arrangement of cell compartments as interacting networks. A respective Lab-on-a-chip handling platform allows for the direct manipulation on a microscope stage and an incubator-free cell culture. Furthermore, luminescent sensors represent promising tools to be embedded into the microfluidic system to monitor the on-chip conditions or to provide information on cell viability and metabolic activity. Finally, examples for implemented assays on chip will be presented, ranging from cell culture showing the cell behavior in respect to surface functionalization and different growth conditions to finally embedding organ-on-chip structures of cultured cell lines.

关键词： Cell-based assays Organ-on-chip microfluidics sensor on chip cell culture microfluidic cell assay toolbox microfluidic toolbox

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Optimization of oxygen sensitive optical dye membrane polymers for fluorescent lifetime based physiological biosensing

Optimization of oxygen sensitive optical dye membrane polyme...

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conference on smart biomedical and physiological sensor technology

作者： Chatni, M. R. Maier, D. E. Porterfield, D. M. Purdue Univ Bindley Biosci Ctr Physiol Sensing Facil W Lafayette IN 47906 USA Purdue Univ Dept Arg & Biol Eng W Lafayette IN 47906 USA Purdue Univ Weldon Sch Biomed Engn W Lafayette IN 47906 USA Purdue Univ Dept Hort & Landscape Architecture W Lafayette IN 47906 USA

ISBN: (纸本)9780819469199

Fiber optic based sensor technologies have many significant advantages over electrochemical sensors, and as a result have broad application for sensing in biology, agriculture and medicine. An important component of fiber optic biosensor is the sensing element. Usually, a polymer matrix containing the analyte specific fluorescent dye is immobilized on one end of the fiber optic probe. The polymer matrix provides mechanical stability to the immobilized membrane and entraps the fluorescent dye molecules. The target analyte diffuses into the membrane polymer and quenches the fluorescent dye. This optical interaction between the analyte and fluorescent dye dynamically changes the fluorescence lifetime of the dye. These changing fluorescent lifetimes reveal information about the target analyte concentration. Although the fluorescent lifetime of the dye is of primary interest, high signal-to-noise ratio (SNR) is also very desirable. Conventionally, complex electronics is implemented to achieve high SNR_ Various signal processing methods such as signal amplification and filtering are implemented to achieve high SNR_ In this study, we report optical signal amplification by modification of the dye-polymer matrix by addition of titanium oxide particles. The addition of titanium oxide particles enhanced the optical signal intensity. Optical performances of different sizes and concentrations of titanium oxide particles are compared. We believe that this increased optical intensity is due to increased optical scattering in the dye-polymer matrix. We also compare the performance of titanium oxide particles to gold and other material particles to experimentally probe the exact nature of light scattering in the dye-polymer matrix.

关键词： optrode fluorescent lifetime titanium (IV) oxide microparticles oxygen multiple scattering

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Hyperspectral Imaging to Discern Malignant and Benign Canine Mammary Tumors

Hyperspectral Imaging to Discern Malignant and Benign Canine...

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conference on smart biomedical and physiological sensor technology X

作者： Sahu, Amrita McGoverin, Cushla Pleshko, Nancy Sorenmo, Karin Won, Chang-Hee Temple Univ Control Sensor Network & Percept CSNAP Lab Dept Elect & Comp Engn Philadelphia PA 19122 USA Temple Univ Dept Bioengn Tissue Imaging & Spectroscopy Lab Philadelphia PA 19122 USA Univ Penn Sch Vet Med Oncol Sect Philadelphia PA 19104 USA

ISBN: (纸本)9780819495105

Hyperspectral imaging is an emerging technology in the field of biomedical engineering which may be used as a non-invasive modality to characterize tumors. In this paper, a hyperspectral imaging system was used to characterize canine mammary tumors of unknown histopathology (pre-surgery) and correlate these results with the post-surgical histopathology results. The system consisted of a charge coupled device (CCD) camera, a liquid crystal tunable filter in the near infrared range (650-1100 nm) and a controller. Spectral signatures of malignant and benign canine mammary tumors were extracted and analyzed. The reflectance intensities of malignant tumor spectra were generally lower than benign tumor spectra over the entire wavelength range. Previous studies have shown that cancerous tissues have a higher hemoglobin and water content, and lower lipid concentration with respect to benign tissues. The decreased reflectance intensity observed for malignant tumors is likely due to the increased microvasculature and therefore higher blood content of malignant tissue relative to benign tissue. Peaks at 700, 840, 900 and 970 nm were observed in the second derivative absorption spectra, these peaks were attributed to deoxy-hemoglobin, oxy-hemoglobin, lipid and water respectively. A 'Tissue Optical Index' was developed that enhances contrast between malignant and benign canine tumors. This index is based on the ratio of the reflectance intensity values corresponding to the wavelengths associated with the four chromophores. Preliminary results from 22 canine mammary tumors showed that the sensitivity and specificity of the proposed method is 85.7% and 94.6% respectively. These results show promise in the non-invasive optical diagnosis of canine mammary cancer.

关键词： Hyperspectral imaging canine mammary tumor near-infrared spectroscopy tumor characterization

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Embedded Multi-sensor smartwatch for Computationally Intensive Biosignal Processing

Embedded Multi-Sensor Smartwatch for Computationally Intensi...

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2024 biomedical Circuits and Systems conference

作者： Rapa, Picrangelo M. Orlandi, Mattia Zanghieri, Marcello Benini, Luca Benatti, Simone Univ Bologna Bologna Italy Univ Modena & Reggio Emilia Modena Italy Swiss Fed Inst Technol Zurich Switzerland

ISBN: (纸本)9798350354966;9798350354959

Over the past decades, the rapid expansion of the wearable market has led to significant advances in integrated devices and technologies, particularly in smartwatches. These devices can unobtrusively acquire various physiological signals such as ECG, EDA, and PPG, resulting ideal for real-time monitoring of vital parameters in medical diagnostics, consumer health, and sports performance analysis. However, existing commercial solutions often do not focus on health-specific applications and face challenges in sensor integration, hardware/software optimization, and onboard signal processing. This paper introduces GAPWatch, a smartwatch-shaped platform with a PCB size of 49 x 47 x 1.2 mm based on GAP9 SoC for efficient onboard signal processing and designed to acquire ECG, PPG, inertial data, and 16-channels sEMG. The platform also features an ESP32-based radio module for connectivity and an STM32U5 MCU acting as a gateway. The system is validated in three scenarios: high-rate sEMG acquisition and streaming, low-rate ECG, PPG, and IMU data streaming, and onboard heart rate (HR) estimation using a TCN. In the HR estimation scenario, GAPWatch performs an inference every 2 seconds, transmitting results via BLE while consuming only 10.02 mW, yielding a battery life of over 92 hours.

关键词： Embedded Systems Low-Power TinyML Wearable smartwatch

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