The molecular docking problem is to determine how molecules interact with other molecules and plays a key role in understanding how cells function. DockingShop is an integrated environment far interactively steering m...
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The molecular docking problem is to determine how molecules interact with other molecules and plays a key role in understanding how cells function. DockingShop is an integrated environment far interactively steering molecular docking by navigating a ligand or protein to the receptor's estimated binding site. This tool provides a graphical interface for molecular modeling featuring real-time visual guides, interactive manipulation, navigation, optimization, and dynamic visualization enabling users to apply their biological knowledge to steer the docking process.
Displays combining both 2D and 3D views have been shown to support higher performance on certain visualization tasks. However, it is not clear how best to arrange a combination of 2D and 3D views spatially in a displa...
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Displays combining both 2D and 3D views have been shown to support higher performance on certain visualization tasks. However, it is not clear how best to arrange a combination of 2D and 3D views spatially in a display. In this study, we analyzed the eyegaze strategies of participants using two arrangements of 2D and 3D views to estimate the relative position of objects in a 3D scene. Our results show that the 3D view was used significantly more often than individual 2D views in both displays, indicating the importance of the 3D view for successful task completion. However, viewing patterns were significantly different between the two displays: transitions through centrally-placed views were always more frequent, and users avoided saccades between views that were far apart. Although the change in viewing strategy did not result in significant performance differences, error analysis indicates that a 3D overview in the center may reduce the number of serious errors compared to a 3D overview placed off to the side.
This paper describes a new environment for the pre-operative planning of total hip replacement. The system is based on a multimodal/multisensorial interface, which includes advanced software visualisation and evaluati...
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This paper describes a new environment for the pre-operative planning of total hip replacement. The system is based on a multimodal/multisensorial interface, which includes advanced software visualisation and evaluation modules for the planning and state-of-the-art technologies for immersive interface (stereoscopic display, different six degrees of freedom tracking technologies, speech recognition, and haptic feedbacks). This paper is focused on the final clinical application description. More specific visualisation-related modules are described in other related papers.
This work presents the development and application of a visualization and navigation system for planning deep-brain neurosurgeries. This system, which incorporates a digitized and segmented brain atlas, an electrophys...
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Cardiac disorder is one of the important diseases. Three-dimensional visualization and motility analysis of heart are necessaries to diagnosis of cardiac disorder. Because it is an important that diagnosis of cardiac ...
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ISBN:
(纸本)0780389409
Cardiac disorder is one of the important diseases. Three-dimensional visualization and motility analysis of heart are necessaries to diagnosis of cardiac disorder. Because it is an important that diagnosis of cardiac disorder considers changing of shape with the passage of time. The purpose of this paper is to create a standard model of left ventricle myocardium. We restored the lost apex of heart in the process of image acquisition and interpolated. We found an algorithm for it using the least squares method. Furthermore we added some conditions the passed the points in the general least square method. It is an important point to determine the shape of left ventricle myocardium. We expect that the proposed algorithm should be helpful for a development of standard model.
In the Multisense project, several sensorial devices (haptics, speech, visualisation and tracking) are integrated within a virtual reality environment for planning total hip replacement (THR) surgery. In use, a fundam...
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In the Multisense project, several sensorial devices (haptics, speech, visualisation and tracking) are integrated within a virtual reality environment for planning total hip replacement (THR) surgery. In use, a fundamental requirement is the creation of a complete subject-specific model of the lower limb. For THR surgery, the available data is from computed tomography (CT) only. Although CT scans allow accurate extraction of bones and the skin surface, muscles appear as poorly contrasted structures. The challenge is, thus, to produce an intuitive modelling tool that will support interactive deformation of a generic atlas model into a patient-specific model. For this, we first generate synthetic scans along pre-defined slicing axes in patient space. Muscle outlines obtained by an initial mapping of generic atlas models are then superimposed on these slices. These outlines are deformed by simple geometric operations to match the underlying muscle shapes using a novel software tool, the Muscle Modelling Laboratory (MML). The paper presents a shape investigation of the muscles relevant to THR surgery and describes the MML module in operation.
Computer Infrastructure for Systems Biology is the first international conference session dedicated to systems biology informatics held at the 18th International conference on Systems Engineering. Our goal is to bring...
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Computer Infrastructure for Systems Biology is the first international conference session dedicated to systems biology informatics held at the 18th International conference on Systems Engineering. Our goal is to bring forth ideas and collaborations among industrial and academic bioinformaticians, biocomputing professionals, data analysts, and system biologists to facilitate systems biology research and findings. The compilation of twelve full session papers and four poster papers at this meeting represents a snapshot of emerging research and development trends in systems biology informatics.
This study shows an effective way to explore and visualize the structure-activity relationships (SARs) of flavonoids with antioxidant activity using structure- activity maps (SAMs). SAMs are graphical maps plotting mo...
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This study shows an effective way to explore and visualize the structure-activity relationships (SARs) of flavonoids with antioxidant activity using structure- activity maps (SAMs). SAMs are graphical maps plotting molecular descriptors such as NAB or MSI against their biological activities. NAB (number of non-hydrogen atoms and bonds in a molecule) or MSI (molecular similarity index) is used to quantify the chemical structures. SA Ms pro vide a very efficient method for representing and visualizing SAR information in a biochemical database. SAMs also provide a simple and effective way for ordering and grouping compounds. SA Ms were examined for compounds grouped according to NAB to determine important activity trends utilizing structural orderings. SA Ms were used to systematically identify the effects of chemical modification on the activities of compounds and to determine the site and type of modifications for improved activity.
This paper presents a simple and efficient method of forming a 3D text label on a 3D triangulated surface. The label is formed by projecting the 2D contours that define the text silhouette onto the triangulated surfac...
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This paper presents a simple and efficient method of forming a 3D text label on a 3D triangulated surface. The label is formed by projecting the 2D contours that define the text silhouette onto the triangulated surface, forming 3D contour paths. Surface polygons upon which the 3D contour paths lie are retriangulated using a novel approach that forms a polyline defining the region outside the contour. This algorithm produces labeled 3D surfaces that conform to the specifications of the STL format, making them suitable for fabrication by a rapid prototyping machine. We demonstrate the effectiveness of the algorithm in forming flat and extruded labels on non-trivial surfaces.
We propose a progressive method which improves the conventional multigrid V-cycle phase unwrapping (PU) scheme. The method is aimed to accommodate the need of early visualization in solving wrapping problem in phase i...
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We propose a progressive method which improves the conventional multigrid V-cycle phase unwrapping (PU) scheme. The method is aimed to accommodate the need of early visualization in solving wrapping problem in phase image. In essence, this technique formulates the wrapped phase image in a partial differential equation (PDE) and solves it by performing a rough global scale solution in the first grid of multigrid structure and constructing the subsequent levels of detail utilizing the gradients of residual error in coarse and fine grids. The intermediate solution is then superposed to the previous solutions and displayed to the user gradually to get an improved solution. In this paper, we look into the feasibility of utilizing this approach to magnetic resonance imaging (MRI) application. The proposed system is evaluated on simulated as well as actual MRI phase images and shows promising progressive improvement in estimating the unwrapped phase image over the conventional one.
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