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Non-invasive monitoring of red blood cells during cold storage using handheld Raman spectroscopy

TRANSFUSION 2021年第7期61卷 2159-2168页

作者： vardaki, Martha Z. Georg Schulze, Hans Serrano, Katherine Blades, Michael W. Devine, Dana, v Turner, Robin F. B. Univ British Columbia Michael Smith Labs 2185 East Mall Vancouver BC V6T 1Z4 Canada Univ British Columbia Dept Pathol & Lab Med 2211 Wesbrook Mall Vancouver BC V6T 2B5 Canada Univ British Columbia Ctr Blood Res Vancouver BC Canada Canadian Blood Serv Ctr Innovat Ottawa ON Canada Univ British Columbia Dept Chem Vancouver BC Canada Univ British Columbia Dept Elect & Comp Engn Vancouver BC Canada

Background: The current best practices allow for the red blood cells (RBCs) to be stored for prolonged periods in blood banks worldwide. However, due to the individual-related variability in donated blood and RBCs continual degradation within transfusion bags, the quality of stored blood varies considerably. There is currently no method for assessing the blood product quality without compromising the sterility of the unit. This study demonstrates the feasibility of monitoring storage lesion of RBCs in situ while maintaining sterility using an optical approach. Study design and methods: A handheld spatially offset Raman spectroscopy (RS) device was employed to non-invasively monitor hemolysis and metabolic changes in 12 red cell concentrate (RCC) units within standard sealed transfusion bags over 7 weeks of cold storage. The donated blood was analyzed in parallel by biochemical (chemical analysis, spectrophotometry, hematology analysis) and RS measurements, which were then correlated through multisource correlation analysis. Results: Raman bands of lactate (857 cm(-1)), glucose (787 cm(-1)), and hemolysis (1003 cm(-1)) were found to correlate strongly with bioanalytical data over the length of storage, with correlation values 0.98 (95% confidence interval [CI]: 0.86-1.00;p = .0001), 0.95 (95% CI: 0.71-0.99;p = .0008) and 0.97 (95% CI: 0.79-1.00;p = .0004) respectively. Discussion: This study demonstrates the potential of collecting information on the clinical quality of blood units without breaching the sterility using Raman technology. This could significantly benefit quality control of RCC units, patient safety and inventory management in blood banks and hospitals.

关键词： 2D-COS glycolysis hemolysis multisource correlation analysis Raman spectroscopy red blood cell concentrate spatially-offset Raman spectroscopy transfusion

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Immersive college English teaching design based on big data 2

Immersive college English teaching design based on big data

引用

2nd International Conference on Cloud Computing and Mechatronic engineering, I3CME 2022

作者： Liu, Jie School of Foreign Languages Wuhan Business University Hubei Province Wuhan430056 China

ISBN: (纸本)9781510657502

In hodiernal international world, immersive college(CE) teaching based on big data is an essential teaching activity. This teaching mode caters to the trend of globalization, and also greatly improves students' learning acceptance ability. This article studies the immersion based on big data design features of CE teaching mode, combing the concept of big data, immersion teaching means, teaching mode analysis of the characteristics of a typical, and so on, by in large data model, to discuss the design pattern of English teaching effect, and the questionnaire survey results. Based on big data technology, combined with hodiernal current CE teaching mode, based on the existing models on the armed big data tools, make truly rich immersive CE teaching mode characteristic of modern society, like a spark set the prairie ablaze the society as a whole class, let the modern college students immersed in modern CE teaching mode, maximum draw utility. © COPYRIGHT SPIE. Downloading of the abstract is permitted for personal use only.

关键词： Big data

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Microfluidic-Based Oxygen (O2) Sensors for On-Chip Monitoring of Cell, Tissue and Organ Metabolism

BIOSENSORS-BASEL

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BIOSENSORS-BASEL 2022年第1期12卷 6页

作者： Azimzadeh, Mostafa Khashayar, Patricia Amereh, Meitham Tasnim, Nishat Hoorfar, Mina Akbari, Mohsen Shahid Sadoughi Univ Med Sci Yazd Reprod Sci Inst Med Nanotechnol & Tissue Engn Res Ctr Yazd 89195999 Iran Shahid Sadoughi Univ Med Sci Yazd Reprod Sci Inst Stem Cell Biol Res Ctr Yazd 89195999 Iran Shahid Sadoughi Univ Med Sci Sch Med Dept Med Biotechnol Yazd 89165887 Iran IMEC Ctr Microsyst Technol B-9050 Ghent Belgium Univ Ghent B-9050 Ghent Belgium Univ Victoria Dept Mech Engn Lab Innovat Micro Engn LiME Victoria BC V8P 5C2 Canada Univ Victoria Ctr Adv Mat & Related Technol Victoria BC V8P 5C2 Canada Univ Victoria Dept Mech Engn Victoria BC V8P 5C2 Canada Silesian Tech Univ Biotechnol Ctr Akad 2A PL-44100 Gliwice Poland

Oxygen (O-2) quantification is essential for assessing cell metabolism, and its consumption in cell culture is an important indicator of cell viability. Recent advances in microfluidics have made O-2 sensing a crucial feature for organ-on-chip (OOC) devices for various biomedical applications. OOC O-2 sensors can be categorized, based on their transducer type, into two main groups, optical and electrochemical. In this review, we provide an overview of on-chip O-2 sensors integrated with the OOC devices and evaluate their advantages and disadvantages. Recent innovations in optical O-2 sensors integrated with OOCs are discussed in four main categories: (i) basic luminescence-based sensors;(ii) microparticle-based sensors;(iii) nano-enabled sensors;and (iv) commercial probes and portable devices. Furthermore, we discuss recent advancements in electrochemical sensors in five main categories: (i) novel configurations in Clark-type sensors;(ii) novel materials (e.g., polymers, O-2 scavenging and passivation materials);(iii) nano-enabled electrochemical sensors;(iv) novel designs and fabrication techniques;and (v) commercial and portable electrochemical readouts. Together, this review provides a comprehensive overview of the current advances in the design, fabrication and application of optical and electrochemical O-2 sensors.

关键词： oxygen sensors microfluidics organ-on-chips (OOCs) on-chip monitoring

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Roadmap on Nonlocality in Photonic Materials and Metamaterials

arXiv

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arXiv 2025年

作者： Monticone, Francesco Mortensen, N. Asger Fernández-Domínguez, Antonio I. Luo, Yu Tserkezis, Christos Khurgin, Jacob B. Shahbazyan, Tigran v. Chaves, André J. Peres, Nuno M.R. Wegner, Gino Busch, Kurt Hu, Huatian della Sala, Fabio Zhang, Pu Ciracì, Cristian Aizpurua, Javier Babaze, Antton Borisov, Andrei G. Chen, Xue-Wen Christensen, Thomas Yan, Wei Yang, Yi Hohenester, Ulrich Huber, Lorenz Wubs, Martijn de Liberato, Simone Gonçalves, P.A.D. de Abajo, F. Javier García Hess, Ortwin Tarasenko, Illya Cox, Joel D. Jelver, Line Dias, Eduardo J.C. Sánchez, Miguel Sánchez Margetis, Dionisios Gómez-Santos, Guillermo Stauber, Tobias Tretyakov, Sergei Simovski, Constantin Pakniyat, Samaneh Gómez-Díaz, J. Sebastián Bondarev, Igor v. Biehs, Svend-Age Boltasseva, Alexandra Shalaev, vladimir M. Krasavin, Alexey v. Zayats, Anatoly v. Alù, Andrea Song, Jung-Hwan Brongersma, Mark L. Levy, Uriel Long, Olivia Y. Guo, Cheng Fan, Shanhui Bozhevolnyi, Sergey I. Overvig, Adam Prudêncio, Filipa R. Silveirinha, Mário G. Gangaraj, S. Ali Hassani Argyropoulos, Christos Huidobro, Paloma A. Galiffi, Emanuele Yang, Fan Pendry, John B. Miller, David A.B. School of Electrical and Computer Engineering Cornell University IthacaNY14853 United States POLIMA Center for Polariton-driven Light–Matter Interactions University of Southern Denmark Campusvej 55 Odense MDK-5230 Denmark D-IAS—Danish Institute for Advanced Study University of Southern Denmark Campusvej 55 Odense MDK-5230 Denmark Departamento de Física Teórica de la Materia Condensada Universidad Autónoma de Madrid MadridE-28049 Spain Universidad Autónoma de Madrid MadridE-28049 Spain School of Electrical and Electronic Engineering Nanyang Technological University Singapore639798 Singapore Key Laboratory of Radar Imaging and Microwave Photonics Ministry of Education College of Electronic and Information Engineering Nanjing University of Aeronautics and Astronautics Nanjing211106 China Department of Electrical and Computer Engineering Johns Hopkins University BaltimoreMD21218 United States Department of Physics Jackson State University JacksonMS39217 United States Department of Physics Aeronautics Institute of Technology SP So Jos dos Campos12228-900 Brazil Departamento de Física Universidade do Minho BragaP-4710-057 Portugal Av Mestre José Veiga Braga4715-330 Portugal Max-Born-Institut Berlin12489 Germany Humboldt-Universität zu Berlin Institut für Physik AG Theoretische Optik and Photonik Berlin12489 Germany Center for Biomolecular Nanotechnologies Istituto Italiano di Tecnologia Via Barsanti 14 Arnesano73010 Italy Via Monteroni Campus Unisalento Lecce73100 Italy School of physics Huazhong University of Science and Technology Luoyu Road 1037 Wuhan430074 China Donostia International Physics Center DIPC Donostia-San Sebastián20018 Spain Ikerbasque Basque Foundation for Science Bilbao48009 Spain Department of Electricity and Electronics University of the Basque Country Leioa48940 Spain Department of Applied Physics University of the Basque Country Donostia20018 Spain Université Paris-Saclay CNRS Institut des Scienc

Photonic technologies continue to drive the quest for new optical materials with unprecedented responses. A major frontier in this field is the exploration of nonlocal (spatially dispersive) materials, going beyond the local, wavevector-independent assumption traditionally made in optical material modeling. On one end, the growing interest in plasmonic, polaritonic and quantum materials has revealed naturally occurring nonlocalities, emphasizing the need for more accurate models to predict and design their optical responses. This has major implications also for topological, nonreciprocal, and time-varying systems based on these material platforms. Beyond natural materials, artificially structured materials—metamaterials and metasurfaces–can provide even stronger and engineered nonlocal effects, emerging from long-range interactions or multipolar effects. This is a rapidly expanding area in the field of photonic metamaterials, with open frontiers yet to be explored. In the case of metasurfaces, in particular, nonlocality engineering has become a powerful tool for designing strongly wavevector-dependent responses, enabling enhanced wavefront control, spatial compression, multifunctional devices, and wave-based computing. Furthermore, nonlocality and related concepts play a critical role in defining the ultimate limits of what is possible in optics, photonics, and wave physics. This Roadmap aims to survey the most exciting developments in nonlocal photonic materials, highlight new opportunities and open challenges, and chart new pathways that will drive this emerging field forward–toward new scientific discoveries and technological advancements. Copyright © 2025, The Authors. All rights reserved.

关键词： Nanocrystals

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design and Performance Optimization of Lead Free CH3NH3SnI3 Perovskite Solar Cell by Numerical Simulation

Design and Performance Optimization of Lead Free CH3NH3SnI3 ...

引用

Workshop on Recent Advances in Photonics (WRAP)

作者： T Keerthi Priya Prasenjit Deb Anwesha Choudhury School of Electronics and Communication Engineering REVA University India

ISBN: (数字)9798350340839

ISBN: (纸本)9798350340846

A high-efficiency organic-inorganic hybrid device opens a new era for accomplishing clean energy. This paper demonstrated the fabrication of TiO 2 thin-film (TF) over CH 3 NH 3 SnI 3 (lead-free) TF hybrid device for solar cell application using the SCAP-1D numerical simulator. The thickness of the TiO2 TF and CH 3 NH 3 SnI 3 TF was optimized to be 200 nm and 700 nm, respectively. The experimental optical absorptions of the individual materials were incorporated with the device parameters. High photosensitivity was reported for the device at zero bias under AM 1.5G illumination (300 to 900 nm) condition. Moreover, a high carrier generation rate with enhanced electron current density was observed for the solar device. Simulated device parameters like efficiency, open-circuit voltage, short circuit current density, and fill-factor were found to be 19.29 %, 0.854 v, 27.21 mA/cm 2 and 82.9 % respectively. In addition, the impact of the device parameters concerning temperature was also studied. The simulated result showed that with increase in temperature, the performance parameters of the device were reduced due to the deformation of interfacial layers and decreasing the mean free path of carriers with temperature.

关键词： Performance evaluation Photovoltaic cells Short-circuit currents Lighting voltage Lead Perovskites Titanium dioxide Junctions Photonics

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稀疏码分多址技术发展及前景

引用

科学技术与工程 2023年第5期23卷 1789-1798页

作者：雷拓峰倪淑燕崔亮程乃平宋鑫陈世淼航天工程大学研究生院北京101416 航天工程大学电子与光学工程系北京101416 66407部队北京100144

提升频谱资源利用率是未来移动通信亟待解决的一项重要目标。其中,稀疏码分多址(sparse code multiple access,SCMA)技术具备频谱利用率高、抗干扰性能力强、系统兼容性好等优点,已成为一种非常有前景的非正交多址方案。为了在未来移动... 详细信息

提升频谱资源利用率是未来移动通信亟待解决的一项重要目标。其中,稀疏码分多址(sparse code multiple access,SCMA)技术具备频谱利用率高、抗干扰性能力强、系统兼容性好等优点,已成为一种非常有前景的非正交多址方案。为了在未来移动通信中进一步发展稀疏码分多址技术,综述了现有稀疏码分多址技术的研究成果,对其研究现状进行了总结分析。首先,分析了现有的码本设计方案,指出了其设计特点以及目前尚存在的问题,并给出相应的解决方案;其次,在解码算法方面,给出了目前两种常见的解码算法,简述了其基本原理,并介绍了一些新兴的解码算法;再次,就SCMA技术与其他技术结合而言,从3个方面总结了目前SCMA技术的研究成果,并探讨了SCMA技术在应用层面潜在的发展的方向;最后,总结了稀疏码分多址技术的发展挑战和趋势。

关键词：稀疏码分多址技术码本设计解码算法稀疏码分多址应用

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Recent developments in research of double glow plasma surface alloying technology: a brief review

引用

JOURNAL OF MATERIALS RESEARCH AND TECHNOLOGY-JMR&T 2020年第3期9卷 6859-6882页

作者： Yuan, Shuo Lin, Naiming Zeng, Qunfeng Zhang, Hongxia Liu, Xiaoping Wang, Zhihua Wu, Yucheng Taiyuan Univ Technol Inst New Carbon Mat Taiyuan 030024 Shanxi Peoples R China Taiyuan Univ Technol Coll Mat Sci & Engn Taiyuan 030024 Shanxi Peoples R China Taiyuan Univ Technol Shanxi Key Lab Mat Strength & Struct Impact Taiyuan 030024 Shanxi Peoples R China Xi An Jiao Tong Univ Key Lab Educ Minist Modern Design & Rotor Bearing Syst Xian 710049 Shaanxi Peoples R China

Higher performance is steadily required in the field of material surface engineering, especially in terms of surface degradation of mechanical parts and repair and renewal of surfaces. By preparing a more reasonable surface design and improving the surface composition and structure of the material, the surface modification layer can provide an important potential solution to the surface degradation problem. The coatings obtained by double glow plasma surface alloying (DGPSA) technology are a compelling method in current and future applications because of a unique combination of characteristics including pollution-free, the gradient distribution of the alloying elements and the strong metallurgical bonding between the alloying layer and the matrix. In recent years, with the increasing requirements for the surface properties of materials in various environments, the layer prepared by DGPSA technology is developing toward alloying, functionalization and nanometer. This review begins with a brief introduction of double glow plasma surface alloying. The recent developments of the double glow plasma surface alloying technology for improving various surface performance are systematically reviewed in the sight of applied material, background, duplex treatment and duplex coating preparation. (C) 2020 The Authors. Published by Elsevier B.v.

关键词： Surface modification Coatings Double glow plasma surface alloying Duplex treatment Functionalization Nanometer

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Optimization of the profile and material of wire contacts for an IR photodetector 8

Optimization of the profile and material of wire contacts fo...

引用

8th International School and Conference "Saint Petersburg OPEN 2021" on Optoelectronics, Photonics, engineering and Nanostructures, SPbOPEN 2021

作者： Kamarchuk, A.v. Bauman, D.A. Marchenko, A.I. Saint-Petersburg National Research University of Information Technologies Mechanics and Optics Saint-Petersburg197101 Russia

The study is devoted to the influence of the choice of geometry and materials of wire contacts on the reflection coefficient and thermal characteristics of the photodetector and the quality of the device design. The process of diffusion of materials of wire contacts and contact pads on a photodetector crystal is investigated. The studies were carried out on samples that are rather small in size (250x250x400 um). During the experiment, 4 main types of loop geometry were selected (main loop, reverse loop, double reverse loop, long loop). The loops were formed using a gold wire 25 µm in diameter. The quality of microwelds was investigated in 3 ways: shear and pull-off tests, optical observation using a scanning electron microscope (SEM), and contact resistance measurement. The aim of the work is to create a high-quality design of an IR photodetector, which allows achieving a high sensitivity (at least 0.5 A / W), a large dynamic range (at least 40 dB) and low indicators of dark current values. The developed technology ensures high quality of the photodetector design. Due to the low costs of this technological process (wire material, the number of operations required for installation), relative to other technologies, which allows maintaining high performance in the technical component of the photodetector, the installation method may be of practical interest in production. © 2021 Institute of Physics Publishing. All rights reserved.

关键词： Wire

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Autonomous vehicles: Steering the Future of Transportation with Self-Driving Technology and Advanced AI Systems

Autonomous Vehicles: Steering the Future of Transportation w...

引用

Global Conference for Advancement in Technology (GCAT)

作者： Daniel Nareshkumar. M Desidi Narsimha Reddy A. Sowmiya v. Samuthira Pandi Rayala Sateesh N. Hindumathy Department of Electronics and Communication Engineering Saveetha School of Engineering Saveetha Institute of Medical and Technical Sciences SIMATS University Chennai Tamil Nadu India Data Consultant (Data Governance Data Analytics: Enterprise Performance Management AI&ML) Soniks Consulting LLC Texas USA Department of EEE Rajalakshmi Engineering College Chennai Centre for Advanced Wireless Integrated Technology Chennai Institute of Technology Chennai Tamil Nadu India Department of ECE MLR Institute of Technology Hyderabad Department of Artificial Intelligence and Machine Learning Vel Tech Rangarajan Dr.Sagunthala R & D Institute of Science and Technology Chennai

ISBN: (数字)9798350376685

ISBN: (纸本)9798350376692

Autonomous vehicles (Avs) are a game-changer in the transportation industry; they will alter cityscapes, cut down on accidents, and reimagine how people experience mobility. This study investigates the complex relationship between autonomous vehicles and high-tech AI systems, looking at how these two technologies can influence transportation in the future. The paper highlights crucial developments in sensor fusion, machine learning algorithms, and real-time data processing that are essential for the development of fully autonomous systems by analyzing the present status of Av technology. In the first part of the study, the basic technologies that support Avs are described. These technologies include LiDAR, radar, cameras, and GPS. When taken together, they allow Avs to perceive their surroundings and locate themselves. After that, it delves into how AI is helping Avs understand sensor data, make judgments in real-time, and carry out complicated maneuvers, showcasing how advancements in deep learning, neural networks, and predictive analytics are powering these capabilities. Integrating Avs into current transportation infrastructures presents both potential and obstacles, which the paper delves into. Critical situation safety, legal frameworks, cybersecurity risks, and AI decision-making ethics are all covered. In addition to the environmental advantages of improved traffic flow and decreased emissions, the study delves into the possible socioeconomic implications, including shifts in urban design, public transit, and the labor market. The research delves into the existing deployment tactics and the path for scaling Av operations through a thorough analysis of case studies, pilot projects, and industry reports. It determines how prepared different groups are to accept this revolutionary technology, including the general public, lawmakers, and manufacturers. To sum up, the study highlights how important it is for academic institutions, business executives, and governm

关键词： Ethics Machine learning algorithms Urban planning Decision making Sensor fusion Data processing Real-time systems Safety Computer security Autonomous vehicles

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Effect of Partial Pressure of Oxygen, Target current, and Annealing on Dc Sputtered Tungsten Oxide (Wo3) Thin Films for Electrochromic Applications

SSRN

引用

SSRN 2023年

作者： Kumar, K. Naveen Sattar, Sheik Abdul Shaik, Habibuddin Reddy, Ashok G.v. Dhananjaya, Merum Pawar, Amruth S. Prakash, Nunna Guru Jafri, R. Imran Chandrashekar, L.N. Aishwarya, P. Department of Physics Nitte Meenakshi Institute of Technology Yelahanka Bengaluru560064 India Department of Electronics and Communication Nitte Meenakshi Institute of Technology Yelahanka Bengaluru560064 India Centre for Nano-materials and MEMS Nitte Meenakshi Institute of Technology Yelahanka Bengaluru560064 India School of Mechanical Engineering Yeungnam University 280 Daehak-ro Gyeongsangbuk-do Gyoungsan-si38541 Korea Republic of Department of VLSI Design Manipal School of Information Karnataka Manipal576104 India Department of Physics and Electronics Christ University Hosur Road Bengaluru560029 India

Tungsten oxide (WO3) thin films were prepared on Corning (CG) and FTO glass substrates at PaO2 4x10-4 mbar and 8x10-4 mbar using DC magnetron sputtering (DCMs). In this work, we have varied the deposition parameters like partial pressure of oxygen (PaO2), target currents, and temperature. At PaO2 4x10-4 mbar and 8x10-4 mbar samples were deposited at target currents of 50 mA and 100 mA, the maintained growth conditions are RT (substrate temperature 280C), Pre annealed (substrate temperature 4000C), and Post annealed (annealing temperature 4000C). The samples were systematically characterized for vibrational, structural, optical, and Electrochromic (EC) properties by using Raman, XRD, Uv-vis spectrometer, and Electrochemical analyzer respectively. XRD analysis reveals that RT-deposited samples show amorphous nature and pre & post-annealed samples show a crystalline nature for both PaO2. optical transmittance was higher at RT-deposited samples at 50 mA (94% & 92%) and lower at 100 mA (87% & 85%) at the wavelength of 600 nm for both PaO2. From Cv analysis higher cathodic peak current density was observed in RT-deposited samples at 50 mA (-6.49 mAcm-2 & -13.80 mAcm-2) and lower at 100 mA (-5.25 mAcm-2 & -12.88 mAcm-2) for both PaO2. The diffusion coefficient was observed at a higher target current at 100 mA (1.06 x10-7 cm2/s & 9.20 x10-8 cm2/s). For annealed samples optical and EC properties were decreased for both PaO2. © 2023, The Authors. All rights reserved.

关键词： Tungsten compounds

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