This book covers a number of engineered nanotheranostics platforms and nanomedicines applications of FDA-approved medicines for early-stage diagnosis and treatment of cancer. The book focuses on (i) the basic design a...
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ISBN:
(数字)9789819965977
ISBN:
(纸本)9789819965960;9789819965991
This book covers a number of engineered nanotheranostics platforms and nanomedicines applications of FDA-approved medicines for early-stage diagnosis and treatment of cancer. The book focuses on (i) the basic design and bioengineering of safe medicines, (ii) physicochemical understanding of surface engineered medicines and their characteristics, (iii) various examples for site-specific bioimaging and multimode therapies, (iv) stimuli-responsive approaches for targeted drug delivery applications, (v) targeted therapeutics approaches for cancer cells or solid tumor ablations, (vi) targeted mechanisms of administrative biomedicines, (vii) impact of surface modification or engineering of biomedicines for site-selective tumor binding ability, and (vii) requirements for clinical trials and FDA approval. The content of this book appeal to readers who are interested in recent developments of FDA-approved cost-effective rapid cancer imaging and therapeutic platforms.
The two major objectives of sensory aids for the blind are to permit access to printed matter and to permit safe travel through the environment. The difficulties of designing technological means to achieve these objec...
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The two major objectives of sensory aids for the blind are to permit access to printed matter and to permit safe travel through the environment. The difficulties of designing technological means to achieve these objectives are in many respects unrelated to the concerns of the engineering laboratory. Social, economic, political, and logistic considerations all play a role. The "blind population" in the United States includes both the totally blind and those with a wide range of visual impairment. This population totals about 400 000 people in which the aged, the multiply handicapped, and those with significant residual vision predominate. Singly handicapped, working-aged people are the initial targets of the current sensory aids. Expansion of their range of usefulness to larger fractions of the blind population is expected to come later. About 800 agencies serve the blind population in the United States, and in 1967 they were responsible for an annual expenditure of $500 million. In contrast the sensory-aids research and development budget was less than $1 million. Nevertheless, several potentially useful prototype devices have been developed and are about to be evaluated in this country; at least one is of foreign origin. But if these devices are ever to have the opportunity of reaching the blind public, then mechanisms for evaluation, field trials, manufacture, and deployment must be set up. The field of currently active sensory-aids research programs is reviewed. Several programs are concerned with increasing the convenience and accessibility of braille by the application of computer technology. Nevertheless, despite the unquestionable value of these developments, the usefulness of braille is limited by its bulk, its cost, and the transcription time. To provide direct access to printed documents several devices are being developed that transform optical images from a printed page into auditory or tactile displays requiring motivation and training for effective use
This book provides in-depth knowledge about the fabrications, structures, properties and applications of three outstanding electrochemically engineered nanoporous materials including porous silicon, nanoporous alumina...
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ISBN:
(数字)9783319203461
ISBN:
(纸本)9783319203454;9783319372853
This book provides in-depth knowledge about the fabrications, structures, properties and applications of three outstanding electrochemically engineered nanoporous materials including porous silicon, nanoporous alumina and nanotubular titania. The book integrates three major themes describing these materials. The first theme is on porous silicon reviewing the methods for preparation by electrochemical etching, properties and methods for surface functionalization relevant for biosensing applications. Biomedical applications of porous silicon are major focus, described in several chapters reviewing recent developments on bioanalysis, emerging capture probes and drug delivery. The second theme on nanoporous alumina starts with describing the concept of self-organized electrochemical process used for synthesis nanopore and nanotube structures of valve metal oxides and reviewing recent development and progress on this field. The following chapters are focused mainly on optical properties and biosensing application of nanoporous alumina providing the reader with the depth of understanding of the structure controlled optical and photonic properties and design of optical biosensing devices using different detection principles such as photoluminescence, surface plasmon resonance, reflective spectrometry, wave guiding, Raman scattering etc. The third theme is focused on nanotubular titania reviewing three key applications including photocatalysis, solar cells and drug delivery. The book represents an important resource for academics, researchers, industry professionals, post-graduate and high-level undergraduate students providing them with both an overview of the current state-of-the-art on these materials and their future developments.
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