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In search of perfect reads 4

In search of perfect reads

引用

4th IEEE international conference on Computational Advances in Bio and Medical Sciences (ICCABS)

作者： Pal, Soumitra Aluru, Srinivas Indian Inst Technol Dept Comp Sci & Engn Bombay 400076 Maharashtra India Georgia Inst Technol Sch Computat Sci & Engn Coll Comp Atlanta GA 30332 USA

ISBN: (纸本)9781479957897

Background: Continued advances in next generation short-read sequencing technologies are increasing throughput and read lengths, while driving down error rates. Taking advantage of the high coverage sampling used in many applications, several error correction algorithms have been developed to improve data quality further. However, correcting errors in high coverage sequence data requires significant computing resources. Methods: We propose a different approach to handle erroneous sequence data. Presently, error rates of highthroughput platforms such as the Illumina HiSeq are within 1%. Moreover, the errors are not uniformly distributed in all reads, and a large percentage of reads are indeed error-free. Ability to predict such perfect reads can significantly impact the run-time complexity of applications. We present a simple and fast k-spectrum analysis based method to identify error-free reads. The filtration process to identify and weed out erroneous reads can be customized at several levels of stringency depending upon the downstream application need. Results: Our experiments show that if around 80% of the reads in a dataset are perfect, then our method retains almost 99.9% of them with more than 90% precision rate. Though filtering out reads identified as erroneous by our method reduces the average coverage by about 7%, we found the remaining reads provide as uniform a coverage as the original dataset. We demonstrate the effectiveness of our approach on an example downstream application: we show that an error correction algorithm, Reptile, which rely on collectively analyzing the reads in a dataset to identify and correct erroneous bases, instead use reads predicted to be perfect by our method to correct the other reads, the overall accuracy improves further by up to 10%. Conclusions: Thanks to the continuous technological improvements, the coverage and accuracy of reads from dominant sequencing platforms have now reached an extent where we can envision just fil

关键词： Accuracy Bioinformatics Error correction Genomics Next generation networking Prediction algorithms Sequential analysis Next generation sequencing error correction error correction Next generation networks Analyses, Sequence Prediction algorithms Bioinformatics Genomics Perfect next generation sequencing Error analysis

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Embedded SW design issues for distributed applications on mobile terminals

Embedded SW design issues for distributed applications on mo...

引用

international conference on Mobile and Ubiquitous Systems: networking and Services (MobiQuitous)

作者： F. Fummi S. Martini G. Perbellini F. Ricciato M. Turolla Università di Verona Verona Italy Telecom Italia Laboratory Torino Italy Embedded Systems Design Center Verona Italy

Mobile terminals are embedded systems with growing elaboration capacity, even still limited, which are continuously connected to a worldwide communication network. Thus, the idea of embedding in mobile terminals remote computing services seems attractive and it is more and more exploited. This paper evaluates a middleware platform based on the simple object access protocol (SOAP) to develop distributed applications on mobile terminals.

关键词： Application software Embedded system Web server Simple object access protocol Middleware Web and internet services Mobile communication Network servers Mobile computing Communication system security

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Cryptanalysis and Improvement of a Certificateless Proxy Signature Scheme from Bilinear Pairings

Cryptanalysis and Improvement of a Certificateless Proxy Sig...

引用

ACIS international conference on Software Engineering, Artificial Intelligence, networking, and Parallel/distributed computing (SNPD)

作者： Rongbo Lu Dake He Changji Wang College of Mathematics and Computer Science Jishou University Jishou China Laboratory of Information Security and National Computer Gird Southwest Jiaotong University Chengdu China Department of Computer Science Sun Yat-sen University Guangzhou China

Due to avoiding the inherent escrow of identity- based cryptography and yet not requiring certificates to guarantee the authenticity of public keys, Li et al. proposed a certificateless proxy signature scheme from bilinear pairings. As for the security, they claimed their scheme satisfies the security requirements of proxy signature such as strong identifiability, verifiability ,strong undeniabilty, preventions of misuse, and strong unforgeability; and any third party who can even get the signed warrant generated by the original signer can not forge a proxy signature. In this paper, however, we successfully identify a forgery attack against their scheme. That is, based on the proxy signature generated by a proxy signer on a message on behalf of an original signer, an adversary can forge a valid proxy signature on the same message which seemed generated by the proxy signer on behalf of this adversary himself. After production a forged proxy signature, the adversary has the same authority with the original signer to the proxy signer, and the verifier cannot distinguish which one is the real original signer. To thwart this attacks, an improvement is further proposed.

关键词： Identity-based encryption Public key cryptography Public key Security Forgery Digital signatures distributed computing Software engineering Artificial intelligence Educational institutions

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Emergency analysis based on affective computing in universities forum 5th

Emergency analysis based on affective computing in universit...

引用

5th international conference on Artificial Intelligence and Security, ICAIS 2019

作者： Zhang, Lu Wu, Xu Xie, Xiaqing Xu, Jin Zhang, Tianle Key Laboratory of Trustworthy Distributed Computing and Service Ministry of Education Beijing100876 China School of Cyberspace Security BUPT Beijing100876 China Beijing University of Posts and Telecommunications Library Beijing100876 China Cyberspace Institute of Advanced Technology Guangzhou University Guangzhou510006 China

ISBN: (纸本)9783030242701

Emergency analysis for social networking sites have gained increased attention. In order to detect emergencies in University Forums, we present an emergency analysis method based on affective computing. The method detects the emergency and calculates the scores in real-time based on affective computing and the University Public Opinion Ontology (UPO_Ontology) established manually. The method is evaluated on two test datasets. The results show that the UPO_Ontology and affective computing greatly improved the accuracy, recall and F-measure. The method proposed in this paper meets the requirement of real-time detection. What's more, It gain of 1.24% in F-measure over the "event-specific detection" proposed by Laylavi et al. and outperforms emergency detect using contextual semantics by nearly 7.1% in F-measure. The analysis of the emergencies in University Forums will help Universities deal with emergencies more effectively and provide students with better service. © Springer Nature Switzerland AG 2019.

关键词： Semantics

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Fog computing as a defensive approach against distributed Denial of Service (DDoS): a proposed architecture

Fog Computing as a defensive approach against Distributed De...

引用

international conference on computing, Communication and networking Technologies

作者： Bhumika Paharia Kriti Bhushan Department of Computer Engineering National Institute of Technology Kurukshetra Haryana

Cloud computing is a long-established technique which deals with storage and processing of information. In cloud computing, any user is liable to pay and demand according to its particular needs. Due to various limitations of cloud computing like higher latency and more bandwidth consumptions for transmitted information, the origination of Fog computing was essential. Fog computing inherits all the advantages of cloud computing, and also brings computing at the network's edge. In addition, security is a very serious concern for cloud computing. In this paper, fog computing is used as a defensive approach from the day-to-day increasing security threats particularly DDoS attacks in cloud computing. Here an architecture has been proposed to obstruct the malicious traffic generated by the DDoS attack from user to the cloud by utilizing the benefits of fog computing. Fog functions as a filtering layer for the traffic generated and is placed between user and cloud. This paper primarily works to improve the overall performance of the network and enhances reduction in the traffic forwarded to the cloud.

关键词： Fog computing Cloud computing DDoS IP Spoofing Fog defense Fog defense architecture

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distributed, self-stabilizing placement of replicated resources in emerging networks

Distributed, self-stabilizing placement of replicated resour...

引用

international conference on Network Protocols

作者： Bong-Jun Ko D. Rubenstein Department of Electrical Engineering Columbia University NY USA

Emerging large scale distributed networking systems, such as P2P file sharing systems, sensor networks, and ad hoc wireless networks, require replication of content, functionality, or configuration to enact or optimize communication tasks. The placement of these replicated resources can significantly impact performance. We present a novel self-stabilizing, fully distributed, asynchronous, scalable protocol that can be used to place replicated resources such that each node is "close" to some copy of any object. We describe our protocol in the context of a graph with colored nodes, where a node's color indicates the replica/task that it is assigned. Our combination of theoretical results and simulation prove stabilization of the protocol, and evaluate its performance in the context of convergence time, message transmissions, and color distance. Our results show that the protocol generates colorings that are close to the optimal under a set of metrics, making such a protocol ideal for emerging networking systems.

关键词： Intelligent networks Protocols distributed computing Grid computing Wireless sensor networks Peer to peer computing Large-scale systems Sensor systems Computer networks Synchronization

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Facility Location Optimization via Multi-Agent Robotic Systems

Facility Location Optimization via Multi-Agent Robotic Syste...

引用

IEEE international conference on networking, Sensing and Control

作者： Miad Moarref Hassan Sayyaadi Department of Mechanical Engineering Sharif University of Technology Tehran Iran

A facility location problem deals with locating the best place for a group of facilities, among distinct demand points, minimizing a certain locational optimization function. In this paper, distributed, asynchronous, and scalable algorithms are presented for solving a facility location problem known as continuous n-median problem (generalized Fermat-Weber problem) via multi-agent robotic systems. The algorithms are discussed both in continuous and discrete time domain, and their validity is proved. It is also shown that the solution of this facility location problem is the set of points that are the geometric medians of their corresponding Voronoi cells.

关键词： Robot sensing systems Mobile robots Euclidean distance Communication system control Multiagent systems Robustness distributed computing Wireless networks Production systems distributed control

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Dynamic fair bandwidth allocation in multiservice CDMA networks

Dynamic fair bandwidth allocation in multiservice CDMA netwo...

引用

international conference on distributed computing Systems Workshop

作者： Chengzhou Li S. Papavassiliou Broadband Mobile and Wireless Networking Laboratory New Jersey Center for Wireless Networking and Internet Security ECE Department New Jersey Institute of Technology Newark NJ USA

In this paper we study the fundamental problem of allocating with efficiency and fairness the available resources in a CDMA wireless system that supports multi-rate multimedia services. We propose the Channel Adaptive Rate Scheduling (CARS) algorithm which adopts the use of dynamically assigned data rates that match the channel capacity in order to improve the system throughput and overcome the problems associated with the channel changing conditions, the variable system capacity and the transmission power limitation. In addition to the throughput improvement CARS also achieves the objective of fairness by adjusting the users' weights dynamically. The performance analysis and evaluation of our proposed algorithm is achieved via modeling and simulation in terms of achievable throughput and fairness.

关键词： Channel allocation Multiaccess communication Throughput Resource management Multimedia systems Adaptive scheduling Dynamic scheduling Scheduling algorithm Channel capacity Performance analysis

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A Study on Test Platform for Verifying New Wireless networking Technologies via Hardware-in-Loop Simulation

A Study on Test Platform for Verifying New Wireless Networki...

引用

international conference on Cyber-Enabled distributed computing and Knowledge Discovery, CyberC

作者： Lijun Zu Ping Wang Jing Han Fuqiang Liu Qing Ai Yusheng Ji Broadband Wireless Communication and Multimedia Laboratory University of Tongji Shanghai China Graduate University for Advanced Study National Institute of Information Tokyo Japan

For designing a wireless network, field test is mostly preferred for researchers to test and evaluate the system performance. However, it is expensive for field constructions and thus it is not affordable for most researchers. Software simulation is another option. However, the results by simulation may be undesirably biased away the true. This paper proposes a new method to trade off between resource consumption and test veracity, which constructs a hardware-in-loop simulation platform by integrating theoretic computation, computer simulation and hardware-based test. This platform can be used to verify wireless networking technologies, while resource is reduced greatly at the same time.

关键词： Computational modeling Relays Testing Wireless communication Atmospheric modeling Software Signal to noise ratio

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Incorporating a PMF-Based Injury Model into a Multi-Agent Representation of Crowd Behavior

Incorporating a PMF-Based Injury Model into a Multi-Agent Re...

引用

ACIS international conference on Software Engineering, Artificial Intelligence, networking, and Parallel/distributed computing (SNPD)

作者： Frederic D. McKenzie Herbie H. Piland Min Song Department of Electrical and Computer Engineering Virginia Modeling Analysis and Simulation Center (VMASC) Old Dominion University Norfolk VA USA Department of Electrical and Computer Engineering Virginia Modeling Analysis and Simulation Center (VMASC) Old Dominion University Norfolk VA

Throughout the years, much research has been conducted on human behavior models that focus on individual intelligent human agents. Fewer multi-agent based models have addressed group or crowd behavior from a psychological and sociological perspective. We have been focused on incorporating crowd behavior models into control force (police and military) simulations and have developed a real-time crowd simulation capable of generating multiple intelligent agent civilians that exhibit a variety of realistic individual and group behaviors at differing levels of fidelity. One important aspect of modeling realistic crowd behaviors is determining the physiological effects of weapons, both non-lethal and lethal alike, on humans. To this end, we present our categories of non-lethal weapons and their physiological effects that need to be represented. Additionally, this paper describes an injury model developed by the University of Pennsylvania and its integration into our Crowd Federate.

关键词： Injuries Humans Weapons Intelligent agent Force control Decision making Software engineering Artificial intelligence distributed computing Computational modeling

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