Proteomics is a hot pot topic in current, its development experienced from proteins qualitative research to quantitative research. Label-free quantification method is the most widely used protein quantification method...
详细信息
ISBN:
(纸本)9781538637913
Proteomics is a hot pot topic in current, its development experienced from proteins qualitative research to quantitative research. Label-free quantification method is the most widely used protein quantification method. But during the process of label-free quantification, lots of Mass spectrometry (MS) data do not be used so that cause the waste of data resource. In this paper, a quantitative algorithm of protein based on simulated annealing algorithm was proposed to improve the efficiency of the use of MS spectral. This paper is about using all possible peptide ions to extract quantitative information from MS spectral. Verified by Experimental data set about that this protein quantification algorithm can increase the coverage of proteins on the condition of ensured accuracy. This paper focused on the development of proteomics and the analysis and excavation of mass spectrum data, its study results can be widely applied in protein qualification area.
File-based data access represents one of the most common ways of providing input data and retrieving output data in scientific applications. However, in distributedcomputing environments, the execution platform of th...
详细信息
With the advent of clustered systems, more and more parallel computing is required. However a lot of programming skills is needed to write a parallel codes, especially when you want to benefit from the various paralle...
详细信息
Mobile cloud computing is a rapidly increasing technology where user's demand, for cloud contents, might exceed the capability of mobile networks even with 5G. Multicast communication can offer excellent service f...
详细信息
The implied volatility is an important parameter when the trader need to quote the prices of *** famous B-S Model assumes that the implied volatility surface is a constant independent of the option's strike and ti...
The implied volatility is an important parameter when the trader need to quote the prices of *** famous B-S Model assumes that the implied volatility surface is a constant independent of the option's strike and time to *** empirical analysis has proved that implied volatility surface is a non-flat *** are several popular methods to construct the implied volatility *** this paper,the parameter affection and performance of several models are compared and tested by using empirical analysis.
The scientific planning and reasonable layout of the community library has important practical significance for the realization of the nationwide *** the point of view of quantitative analysis,we propose community lib...
The scientific planning and reasonable layout of the community library has important practical significance for the realization of the nationwide *** the point of view of quantitative analysis,we propose community library location model based on the subsection utility function,which not only takes the traffic factors into account,but also considers the environmental *** obtain exact solution of the problem with LINGO software,and discuss the relationship between the number of constraints and the value of the objective function,as well as the coverage *** research results have reference value to the planning and layout of community library.
Maximising the network lifetime is a challenging problem in sensor networks. This paper proposes an evolutionary clustering routing algorithm for heterogeneous wireless sensor networks (WSN). The method combines genet...
详细信息
Automatic cell nuclei detection is a real challenge in medical imagery. The Marked Point Process (MPP) is one of the most promising scalable and paralellizable method. To handle large histopathology images, the algori...
详细信息
In this paper, we present a human body simulator for healthcare research. In this special environment, human body is regarded as a black-box system that generates different outputs corresponding to different external ...
详细信息
ISBN:
(纸本)9781538637913
In this paper, we present a human body simulator for healthcare research. In this special environment, human body is regarded as a black-box system that generates different outputs corresponding to different external inputs. The inputs can be healthcare interventions, and the outputs can be phenotypes that reflect latent health states. The healthcare purpose is to find effective strategies that can make the human body transfer to a healthy state from any other unhealthy states. At first, we propose to use deep neural networks (DNNs) to model the human body system. After some analyses, we discover that the models of neural networks can reflect some real cases. Then, we implement a virtual human body simulator and a deep reinforcement learning (DRL) module. These two modules form a closed loop to do some healthcare experiments. The experiments compare different architectures of the body simulator and illustrate some attributes of the models.
This paper performed multidisciplinary design optimization(MDO) of an AUV hull to minimize the energy consumption for *** hull is decomposed into two disciplines and a multidisciplinary optimization problem is *** des...
This paper performed multidisciplinary design optimization(MDO) of an AUV hull to minimize the energy consumption for *** hull is decomposed into two disciplines and a multidisciplinary optimization problem is *** design feasible(MDF) architecture is adopted for optimization.A CFD-based analysis framework is proposed for resistance calculation of sample points in the hydrodynamics discipline and then a Kriging surrogate model is *** optimal design of AUV hull is obtained and the computational cost is quite low with few high-fidelity CFD simulations.
暂无评论