This paper projects machine learning as a valuable tool for the restriction of the Covid-19 pandemic escalation in the global scenario. The proposed system involves detection of masked or unmasked people and a tempera...
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The need for point-of-care (POC) devices for detecting the onset of sepsis has become critical since sepsis is one of the most prevalent causes of deaths worldwide in non-coronary intensive care units at the hospitals...
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The need for point-of-care (POC) devices for detecting the onset of sepsis has become critical since sepsis is one of the most prevalent causes of deaths worldwide in non-coronary intensive care units at the hospitals. Every one hour delay in exercising proper medication can lead to an exponential rise in mortality. Motivated by this, we propose a POC device for sepsis biomarker detection, which will complement traditional blood culture-based techniques for easy and quicker diagnosis and monitoring of sepsis state. The working principle of the device is based on amalgamation of surface plasmon resonance (SPR) technology with microfluidics. The sensing chip consists of a gold and graphene oxide coated patterned array of periodic nanoposts to detect target biomarker molecules in a limited sample volume. The nanoposts are functionalized with specific receptor molecules that serve as a nanostructured plasmonic crystal for SPR-based bio-sensing via the excitation of surface plasmon polaritons. The sensitivity of the device to one of the known sepsis biomarkers, Pro-calcitonin (PCT), was found to be 0.0643 a.u./ ***(-1) at lower concentration and 0.0224 a.u./ ***(-1) at higher concentration, and a LOD of 1.22 ***(-1). The sensor chip provides an opportunity to dynamically measure antigen-antibody bindings and the soft-lithography based sensor manufacturing technology provides high reproducibility of the sensor response to PCT molecules even at a picomolar level. The microfluidics-based platform provides potential for future integration with other microfluidic devices viz. plasma separator for separating the PCT-sized molecules to enable blood sample measurements
Triboelectric speed sensors (TSS) have the advantage of easy integration to be used to monitor the bearing skidding. However, dry friction between materials can reduce the durability and stability of TSS and interfere...
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Triboelectric speed sensors (TSS) have the advantage of easy integration to be used to monitor the bearing skidding. However, dry friction between materials can reduce the durability and stability of TSS and interfere with the operation of the cage. In this paper, BaTiO3/polyimide (BTO/PI) nanocomposite films and lubricants are introduced to triboelectric nanogenerator (TENG) and the effects of lubricant species and nanoparticles doping mass fraction on tribological and electrification performance are investigated. The results show that the TENG with squalane and BTO/PI nanocomposite film of 20 wt% has a lower friction coefficient and mass loss while higher output and stability. Then, the nano-film composite lubricated TSS (NFCL-TSS) integrated with bearing is constructed based on the rotary freestanding TENG (RF-TENG) with optimal nanocomposite film and squalene, where the signal processing circuit with wireless transmission is integrated on the back of RF-TENG stator to improve the integration of the sensing system. The results show that the NFCL-TSS has 84.81% lower mass loss, 95.26% and 97.75% higher electrical output and stability than that of the TSS with pure PI under dry conditions, respectively. Moreover, the cage speed before and after installation of NFCL-TSS remains mostly unchanged, and the error between the cage speed measured by NFCL-TSS and commercial sensor is below 0.26%. Finally, based on the bearing test platform, the monitoring of skidding is achieved by NFCL-TSS under different speeds and loads. This study provides a new strategy for the design of TSS with high durability, stability and integration.
After the first case has appeared in China, the COVID-19 pandemic continues to pose an omnipresent threat to global health, affecting more than 70 million patients and leading to around 1.6 million deaths. To implemen...
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After the first case has appeared in China, the COVID-19 pandemic continues to pose an omnipresent threat to global health, affecting more than 70 million patients and leading to around 1.6 million deaths. To implement rapid and effective clinical management, early diagnosis is the mainstay. Today, real-time reverse transcriptase (RT)-PCR test is the major diagnostic practice as a gold standard method for accurate diagnosis of this disease. On the other side, serological assays are easy to be implemented for the disease screening. Considering the limitations of today's tests including lengthy assay time, cost, the need for skilled personnel, and specialized infrastructure, both strategies, however, have impediments to be applied to the resource-scarce settings. Therefore, there is an urgent need to democratize all these practices to be applicable across the globe, specifically to the locations comprising of very limited infrastructure. In this regard, sensor systems have been utilized in clinical diagnostics largely, holding great potential to have pivotal roles as an alternative or complementary options to these current tests, providing crucial fashions such as being suitable for point-of-care settings, cost-effective, and having short turnover time. In particular, the integration of smart materials into sensor technologies leverages their analytical performances, including sensitivity, linear dynamic range, and specificity. Herein, we comprehensively review major smart materials such as nanomaterials, photosensitive materials, electrically sensitive materials, their integration with sensor platforms, and applications as wearable tools within the scope of the COVID-19 diagnosis.
Electric field measurements have many scientific applications. Their results can be used in atmospheric electricity, optimisation of electric safety, e.g. lightning protection and meteorology. However, a measurement s...
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ISBN:
(数字)9781665490245
ISBN:
(纸本)9781665490245
Electric field measurements have many scientific applications. Their results can be used in atmospheric electricity, optimisation of electric safety, e.g. lightning protection and meteorology. However, a measurement should be performed equally reliably to draw reliable conclusions. In theory and practice, you can find various measurement methods, some used for many years and which can be verified in terms of their accuracy using the possibility of computer simulations. This work contains a field analysis of examples of electric field sensors, based on which a discussion was held and practical conclusions were drawn. Described measurement methodology is often used for measurements of lightning electric field distribution. The article concerns the theory of sensors for measuring electric field and current based on numerical simulations. It can be used both in the problems of the physics of atmospheric lightning discharges and fair-weather electricity. Electric field E and.E measurements are widely described in the literature and have large technical applications. Measurements of the Maxwell current density and its components for thunderstorm electricity and fair weather conditions are associated with many interpretations and technical difficulties. It may touch cases like currents under a thundercloud approaching or currents from distant discharges. For example, Krider and Musser [1] determined the Maxwell current in a situation where Ez(t)=0 (conduction current is that it always vanishes when E is zero). Current measurement methods based directly on Gauss or Ampere-Maxwell equations and selecting appropriate sensor surfaces to carry out the integration operation on these surfaces or the path that bounds that surface may prove difficult or impossible. It needs to choose a unique Gaussian surface to calculate the electric field and a particular Amperian loop to determine the magnetic field and current density.
An energy-efficient cloud-integrated wireless sensor network (WSN) model is proposed based on request integration and data prediction method. Many users want to access the same sensors in the sensor cloud environment ...
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This research presents an innovative solution aimed at preventing in-vehicle pediatric heatstroke incidents through the integration of advanced sensors, connectivity, and intelligent algorithms. The proposed system co...
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ISBN:
(数字)9798350387179
ISBN:
(纸本)9798350387186
This research presents an innovative solution aimed at preventing in-vehicle pediatric heatstroke incidents through the integration of advanced sensors, connectivity, and intelligent algorithms. The proposed system continuously monitors crucial parameters including occupancy status, temperature, and the child's Respiratory Rate (RR). A hybrid detection approach, combining Force Sensing Resistor (FSR) sensors and motion sensors, is employed to ensure enhanced accuracy. To optimize the system efficiency, the solution utilizes Simplified Frequency Analysis (SFA), offering processing speeds up to 80 times faster than conventional methods, making it ideal for real-time applications. The processed data is seamlessly transmitted via a mobile application, enabling immediate caregiver notification and intervention. Initial testing confirms the solution's high accuracy in occupancy detection and breath monitoring, satisfying automotive standards for temperature resilience and power efficiency. Engineered to withstand extreme environmental conditions ranging from -40° to +85°C, while maintaining a minimal standby current of 104 µA, this technology holds immense potential in not only saving lives but also establishing itself as a standard safety feature.
Breath ammonia is an essential biomarker for patients with many chronic illnesses, such as chronic kidney disease (CKD), chronic liver disease (CLD), urea cycle disorders (UCD), and hepatic encephalopathy. However, ex...
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Breath ammonia is an essential biomarker for patients with many chronic illnesses, such as chronic kidney disease (CKD), chronic liver disease (CLD), urea cycle disorders (UCD), and hepatic encephalopathy. However, existing breath ammonia sensors fail to compensate for the impact of breath humidity and complex breathing motions associated with a human breath sample. Here, a multimodal breath sensing system is presented that integrates an ammonia sensor based on a thermally cleaved conjugated polymer, a humidity sensor based on reduced graphene oxide (rGO), and a breath dynamics sensor based on a 3D folded strain-responsive mesostructure. The miniaturized construction and module-based configuration offer flexible integration with a broad range of masks. Experimental results present the capabilities of the system in continuously detecting diagnostic ranges of breath ammonia under real, humid breath conditions with sufficient sensing accuracy and selectivity over 3 weeks. A machine-learning algorithm based on K-means clustering decodes multimodal signals collected from the breath sensor to differentiate between healthy and diseased breath concentrations of ammonia. The on-body test highlights the operational simplicity and practicality of the system for noninvasively tracing ammonia biomarkers. A wearable multimodal breath sensing system, incorporating an ammonia sensor, humidity sensor, and a 3D folded strain-responsive mesostructure, employs a K-means clustering algorithm to differentiate between concentrations of ammonia in healthy and diseased breath. This holds significant potential for noninvasively tracking breath biomarkers. image
The measurement of pressure drops within microchannels is pivotal for exploring microfluidic flow dynamics and advancing microfluidic device technology. Traditionally, assessing liquid pressure drops in silicon microc...
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ISBN:
(数字)9798350359831
ISBN:
(纸本)9798350359848
The measurement of pressure drops within microchannels is pivotal for exploring microfluidic flow dynamics and advancing microfluidic device technology. Traditionally, assessing liquid pressure drops in silicon microchannels has necessitated alterations to the original design of the microchannels to accommodate the integration of small pressure sensors. This adaptation, however, introduces a limitation: the small size of the sensor compromises its sensitivity, thereby impairing the reliability of pressure drop measurements. This study explored an approach to the application of capacitive pressure sensors, designed to be seamlessly embedded into microchannels, to accurately measure pressure drops in silicon microchannels. By carefully regulating the outlet pressure, the overall absolute pressure in the microchannel was increased without affecting the pressure drop values. This approach enhanced the capacitive pressure sensor’s sensitivity across a broader operational range. The findings from pressure drop tests conducted on a straight microchannel, possessing a hydraulic diameter of 524 μm and examined across a Reynolds number range of 383.8 to 1644.9, align with established macroscopic theories.
COSMIC-SWAMP is an Internet of Things solution designed to support the integration of cosmic ray soil moisture sensors into data-driven irrigation management systems. By automatically accounting for the sensitive foot...
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