A spot-adaptive compound clustering-enhancement-segmentation (CES) scheme was developed for the quantification of gene expression levels in microarray images. The CES-scheme employed 1/griding, for locating spot-regio...
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ISBN:
(纸本)9783540744825
A spot-adaptive compound clustering-enhancement-segmentation (CES) scheme was developed for the quantification of gene expression levels in microarray images. The CES-scheme employed 1/griding, for locating spot-regions, 2/Fuzzy C-means clustering, for segmenting spots from background, 3/background noise estimation and spot's center localization, 4/emphasizing of spot's outline by the CLAHE image enhancement technique, 5/segmentation by the SRG algorithm, using information from step 3, and 6/microarray spot intensity extraction. Extracted intensities by the CES-Scheme were compared against those obtained by the MAGIC TOOL's SRG. Kullback-Liebler metric's values for the CES-Scheme were on average double than MAGIC TOOL's, with differences ranging from 1.45bits to 2.77bits in 7 cDNA images. Coefficient-of-Variation results showed significantly higher reproducibility (p<0.001) for the CES-Scheme in quantifying gene expression levels. processing times for 1024x1024 16-bit microarray images containing 6400 spots were 300 and 487 seconds for the CES-Scheme and MAGIC TOOL respectively.
Convolution is a basic signal and imageprocessing application. In imageprocessing, kernel coefficients of convolution commonly remain constant across the entire image. A less common situation is where the kernel coe...
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Convolution is a basic signal and imageprocessing application. In imageprocessing, kernel coefficients of convolution commonly remain constant across the entire image. A less common situation is where the kernel coefficients change in value for each pixel in the image. We call this variable kernel convolution. In this paper we present what we believe are the first three FPGA implementations of variable kernel convolution. The first uses sequential streaming, the second uses pipelining and the third solution uses what we call convolve and gather and its hardware implementation has the highest area time rating (6.7 x better than streaming and 3.4x better than the pipelining solution). Both pipelining and convolve and gather have the same throughput (which is 25 x that of streaming), but convolve and gather has 71% smaller area footprint than the pipeline.
In this paper, we present the imaging parameters and compare both mercuric iodide (HgI2) and amorphous selenium (a-Se) films. Using MCNPx code, we designed the film structure and its thickness for the optimized detect...
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ISBN:
(纸本)3908451310
In this paper, we present the imaging parameters and compare both mercuric iodide (HgI2) and amorphous selenium (a-Se) films. Using MCNPx code, we designed the film structure and its thickness for the optimized detector in the diagnostic x-ray range. The mercuric iodide film was formed by a wet binder process, while the amorphous selenium film was deposited by physical vapor deposition (PVD). These deposition methods are capable of being scaled up to sizes required in diagnostic imaging applications. The electronic properties are investigated using dark current, x-ray sensitivity and signal to noise ratio (SNR). From our results, the developed HgI2 film as an alternative to a-Se photoconductor, which is in practical use in flat panel x-ray imaging detector, will prove its usefulness in the future design and the optimization for various diagnostic modalities.
Plasma facing components (PFC) in Tore Supra and W7x adopt the flat tile concept using carbon fibre composite (CFC) material for the plasma facing material. As the cooling structure is made of a copper alloy material ...
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Plasma facing components (PFC) in Tore Supra and W7x adopt the flat tile concept using carbon fibre composite (CFC) material for the plasma facing material. As the cooling structure is made of a copper alloy material (CuCrZr), the bonding technique between CFC tiles and CuCrZr is critical. Currently, a soft metallic compliant layer is interposed between the two;in such a way the significant thermal expansion mismatch between carbon and copper can be accomodated. The development of a reliable non-destructive inspection technique (NDT) for the bond, to be performed during the manufacturing process, is obviously of great importance. The SATIR ( infrared thermography) test bed operating at Commisariat a l'Energie Atomique (CEA) Cadarache performs this function using transient infrared thermography: the thermal excitation is realized in the cooling channel and the presence of a faulty tile is detected in the form of a delayed thermal response. With this technique, the evolution of the surface temperature of an inspected element was compared to that of a defined free-defect element, using the so-called DTref criterion ( maximum of the transient temperature difference). The defect detection capability of the SATIR test bed can be improved using signalprocessing methods. A first treatment based on spatial image autocorrelation allows a better localization of the bond defect. Moreover, the problem of detection and classification of random signals ( like the thin defect signature) can be solved maximizing the signal-to-noise ratio (SNR). Two filters maximizing this ratio were optimized: the stochastic matched filter (SMF) aims at defect detection, while the constrained SMF aims at defect classification. These methods assume that the second-order properties of the process at play are known, through covariance matrices. All these methods process the SATIR signal utilizing any free-defect element as reference signal. The tile temperature signal is either processed by itself or
This paper presents an advanced CMOS imager with concurrent parallel processing for early-vision tasks. The network is arranged in two layers of 32×32 programmable mixed-signal elementary processors with programm...
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The logarithmic imageprocessing (LIP) theory is a mathematical framework that provides a set of specific algebraic and functional operations and structures that are well adapted to the representation and processing o...
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The logarithmic imageprocessing (LIP) theory is a mathematical framework that provides a set of specific algebraic and functional operations and structures that are well adapted to the representation and processing of non-linear images, and more generally of non-linear signals, valued in a bounded intensity range. This very well structured theory determined us to use the logarithmic image representation in our approach for defining a new set of mathematical morphology operators based upon structuring elements with a variable geometrical shape or adaptative structuring elements. The purpose of this paper is to define and to analyze the new multiplicative logarithmic morphological operators used in medical image enhancement. Finally, the experimental results reveal that this method has wide potential areas of impact which may include: Digital x-ray, Digital Mammography, Computer Tomography Scans, Nuclear Magnetic Resonance imagery and Telemedicine applications.
This paper describes several system-level interconnection strategies for a coarse-grained reconfigurable fabric designed for low-energy hardware acceleration. A small, representative sub-graph for signal and image pro...
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This paper describes several system-level interconnection strategies for a coarse-grained reconfigurable fabric designed for low-energy hardware acceleration. A small, representative sub-graph for signal and imageprocessingapplications is used to predict the success of mapping larger applications onto the fabric device with these different interconnection strategies, which include 32:1, 8:1, 5:1, 4:1, 3553:1 (3:1, 5:1, 5:1, 3:1) and 355:1 (3:1, 5:1, 5:1) cardinalities. Three mapping techniques are presented and used to complete mappings onto several of these fabric instances including a mixed integer linear programming technique, a constraint programming approach, and a greedy heuristic. We present results for area (in number of required rows), power, delay, and energy as well as run times for mapping a set of signal and imageprocessing benchmarks onto each of these interconnects. Our results indicate that the 5:1 interconnect provides the best overall results and does not require any additional hardware resources than the baseline 4:1 technique. When compared with other implementation strategies, the reconfigurable fabric energy consumption, using 5:1-based interconnect, is within 5-10x of a direct ASIC implementation, is 10x better than an Virtex II Pro FPGA and is 100x better than an Intel xScale processor.
The project's main goal is the development of an interactive 3D atlas, that allows detailed exploration of the rat brain as well as illustration of interactions and information flows between various brain structur...
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ISBN:
(纸本)3540710906
The project's main goal is the development of an interactive 3D atlas, that allows detailed exploration of the rat brain as well as illustration of interactions and information flows between various brain structures. Compared to other software on the market, this tool will focus more on the specific needs of scientists and students. Simplicity of use is one of its keys features. Students and scientists should be able to easily manipulate and view data that the system provides. Especially scientists should be able to import or add results and compare or illustrate them within a unified framework. The software will run on normal consumer hardware and not require expensive workstations, so that students can use it for learning purposes at home, as well as scientists being able to add data from their regular work PCs. Despite not having high hardware requirements, it will make use of various visualization effects.
The problem of recovering a sparse signalx Rn from a relatively small number of its observations of the form y = Ax Rk, where A is a known matrix and k « n, has recently received a lot of attention under the rub...
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The problem of recovering a sparse signalx Rn from a relatively small number of its observations of the form y = Ax Rk, where A is a known matrix and k « n, has recently received a lot of attention under the rubric of compressed sensing (CS) and has applications in many areas of signalprocessing such as data cmpression, imageprocessing, dimensionality reduction, etc. Recent work has established that if A is a random matrix with entries drawn independently from certain probability distributions then exact recovery of x from these observations can be guaranteed with high probability. In this paper, we show that Toeplitz-structured matrices with entries drawn independently from the same distributions are also sufficient to recover x from y with high probability, and we compare the performance of such matrices with that of fully independent and identically distributed ones. The use of Toeplitz matrices in CS applications has several potential advantages: (i) they require the generation of only O(n) independent random variables; (ii) multiplication with Toeplitz matrices can be efficiently implemented using fast Fourier transform, resulting in faster acquisition and reconstruction algorithms; and (iii) Toeplitz-structured matrices arise naturally in certain application areas such as system identification.
Improved SAFT imaging methodologies are discussed for the inspection of composite materials and coarse‐grained polycrystalline materials. The problem of unfavourable beam fields of conventional transducers, which occ...
Improved SAFT imaging methodologies are discussed for the inspection of composite materials and coarse‐grained polycrystalline materials. The problem of unfavourable beam fields of conventional transducers, which occurs for specific elastic material properties, is solved by using a two‐dimensional array for beam focusing and steering. Additionally, redundant sets of rf‐data are acquired and used for image reconstruction by exciting the transmit and receive elements, respectively, in variable subsets, revealing the promising potential of sparse array applications.
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