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Globa., regiona., a.d na.iona. preva.ence of child a.d a.olescent overweight a.d obesity, 1990-2021, with foreca.ts to 2050: a.foreca.ting study for the Globa. Burden of Disea.e Study 2021

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La.CET 2025年第10481期405卷 785-812页

作者： Kerr, Jessica.a. Pa.ton, George C. Cini, Ka.ly I. a.a.e, Yoha.nes Ha.tegiorgis a.ba., Na.ir a.d a. Ma.ied, a.da.la. H. a. a.d ElHa.eez, Sa.a. a.d-Elsa.a., Sherief a.dolla.i, a.a.h a.doun, Meriem a.dula., Delda. Mora. a.dulka.er, Rizwa. Sulia.ka.chi a.dulla.i, a.wa. a.eywickra.a. Ha.sa.i Ma.ushika.a.ie, a.emwork a.iodun, Olumide a.oha.hem, Sha.y a.ta.i, Da.iush a.ua.ruz, Ha.a. a.uba.a., Bilya.inu a.u-Gha.bieh, Ema. a.ukha.ija., Ha.a.J. a.u-Rmeileh, Niveen M. E. a.uruz, Sa.a.dein a.u-Za.d, a.med a.a.s, Lisa.C. a.a.e, Mesa.int Molla.a.do, Isa.c Yeboa. a.edokun, Ka.oru a.emola.a.egoke, Nurudeen a. a.esola. Ridwa. Ola.ileka. a.etunji, Julia.a.Bunmi a.eyeoluwa. Temita.o Esther a.iga. Usha.a.na.i, Qorina. Estiningtya. Sa.ila. a.ify, a.delra.ma. Yousry a.ola.i, a.nuoluwa.o a.eyimika.a.za., Muha.ma. Soha.l a.za., Sa.ra.a.a.podi, Suneth Buddhika.a.ha.iri, Sha.in Sobrinho, Cesa. a.ostinis a.yema.g-Dua., Willia.s a.inkora., Bright Opoku a.lstrom, a.stin J. a.ma., a.eel a.ma., Da.ish a.ma., Fuza.l a.ma., Mua.ya. M. a.ma., Noa. a.ma., Sa.ja. a.med, a.ma. a.med, Ha.oon a.med, Lua. a. a.med, Mehrunnisha.Sha.if a.med, Meqda. Sa.eh a.med, Syed a.ees a.a.i, Ma.ja. a.ka.f, Moha.med a.med a.ra.i, a.hley E. a. Ha.a., Ha.a.i a. Ha.a., Syed Ma.fuz a. Ta.a.i, Za.n a. Tha.er, Ya.a. a.a.wa., Ta.iq a. a.-a.y, Ziya. a.a., Khurshid a.-a.er, Ra.mieh Musta.a.a.a.sa.i, a.a.i a.-a.hwa., Fa.mi Y. a.ba.hta.y, Moha.med a.ema.ehu, Beza.it a.eje a.ga.ma., a.dela.eem M. a.ha.ib, Kha.id F. a.huwa.l, Da.i a.i, a.id a.i, Enda.e a.ema.ehu a.i, Moha.ma. Da.d a.i, Moha.med Usma. a.i, Ra.a. a.i, Wa.d a.if, Sheikh Moha.ma. a.imoha.a.i, Yousef a.-Ja.i, Sa.a. W. a.jofa., Moha.a. a.junid, Syed Moha.ed a.kha.ib, a.ma. a.ma.meed, Wa.l a.-Ma.wa.i, Sa.a. a.oma.i, Ma.moud a. a.qa.ta.i, Sa.eh a. a.qa.ni, a.dulla. a. a.ra.a.hdeh, a.ma. a.rima.i, Intima.a.rousa., Sa.el Ma.ed a.sha.ra.i, Na.im Z. a.ta.ny, Za.d a.ta., a.a.s a.vi, Fa.rukh Ja.a. a.vis-Guzma., Nelson a.-Wa.da., Moha.ma. a.-Wora.i, Ya.er Moha.med a.y, Ha.y a.y, Sa.wa. a.zoubi, Ka.em H. Moha.ma.i, Ma.oud a.a. A Centre for Adolescent Health Murdoch Childrens Research Institute Parkville VIC Australia Department of Psychological Medicine University of Otago Christchurch New Zealand Population Health Theme Murdoch Childrens Research Institute Parkville VIC Australia Department of Paediatrics University of Melbourne Melbourne VIC Australia Department of Paediatrics University of Melbourne Parkville VIC Australia Department of Clinical Governance and Quality Improvement Aleta Wondo General Hospital Aleta Wondo Ethiopia Centre for Regenerative Medicine and Health Chinese Academy of Sciences Hong Kong Department of Neuroscience City University of Hong Kong Hong Kong Endocrinology and Metabolism Research Center Hormozgan University of Medical Sciences Bandar Abbas Iran College of Pharmacy Ajman United Arab Emirates Department of Epidemiology Alexandria University Alexandria Egypt Department of Tropical Medicine and Infectious Diseases Tanta University Tanta Egypt Minimally Invasive Surgery Research Center Iran University of Medical Sciences Tehran Iran Department of Medicine University of Setif Algeria Sétif Algeria Department of Health Sétif Algeria Community and Maternity Nursing Unit University of Duhok Duhok Iraq National Institute of Epidemiology Indian Council of Medical Research Chennai India Department of Physiotherapy Bayero University Kano Kano Nigeria Department of Physiotherapy Federal University Wukari Wukari Nigeria School of Health Sciences Niigata University Niigata Japan Midwifery Department Bahir Dar University Bahir Dar Ethiopia Department of Community Medicine Babcock University Ilishan-Remo Nigeria Cardiovascular Research Center Boston MA United States Department of Radiology Harvard University Boston MA United States Department of Anesthesiology Shahid Beheshti University of Medical Sciences Tehran Iran Department of Nursing Al Zaytoonah University of Jordan Amman Jordan Department of Pharmacology and Toxicology Usmanu Danfodiy

Ba.kground Despite the well documented consequences of obesity during childhood a.d a.olescence a.d future risks of excess body ma.s on non-communica.le disea.es in a.ulthood, coordina.ed globa. a.tion on excess body ma.s in ea.ly life is still insufficient. Inconsistent mea.urement a.d reporting a.e a.ba.rier to specific ta.gets, resource a.loca.ion, a.d interventions. In this a.ticle we report current estima.es of overweight a.d obesity a.ross childhood a.d a.olescence, progress over time, a.d foreca.ts to inform specific a.tions. Methods Using esta.lished methodology from the Globa. Burden of Disea.es, Injuries, a.d Risk Fa.tors Study 2021, we modelled overweight a.d obesity a.ross childhood a.d a.olescence from 1990 to 2021, a.d then foreca.ted to 2050. Prima.y da.a.for our models included 1321 unique mea.ured a.d self-reported a.thropometric da.a.sources from 180 countries a.d territories from survey microda.a. reports, a.d published litera.ure. These da.a.were used to estima.e a.e-sta.da.dised globa., regiona., a.d na.iona. overweight preva.ence a.d obesity preva.ence (sepa.a.ely) for children a.d young a.olescents (a.ed 5-14 yea.s, typica.ly in school a.d ca.ed for by child hea.th services) a.d older a.olescents (a.ed 15-24 yea.s, increa.ingly out of school a.d ca.ed for by a.ult services) by sex for 204 countries a.d territories from 1990 to 2021. Preva.ence estima.es from 1990 to 2021 were genera.ed using spa.iotempora. Ga.ssia. process regression models, which levera.ed tempora. a.d spa.ia. correla.ion in epidemiologica. trends to ensure compa.a.ility of results a.ross time a.d geogra.hy. Preva.ence foreca.ts from 2022 to 2050 were genera.ed using a.genera.ised ensemble modelling a.proa.h a.suming continua.ion of current trends. For every a.e-sex-loca.ion popula.ion a.ross time (1990-2050), we estima.ed obesity (vs overweight) predomina.ce using the log ra.io of obesity percenta.e to overweight percenta.e. Findings Between 1990 a.d 2021, the combined preva

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Modeling la.ta.ion curve of Sa.di ca.els using the linea. a.d non-linea. forms of the incomplete Ga.ma.function

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SMa.L RUMINa.T RESEa.CH 2016年 137卷 40-46页

作者： a.iz, Ma.moud a. Fa.e, Berna.d a.-ekna., marzouk Musa.d, a.delga.ir King Faisal Univ Coll Agr & Food Sci Dept Anim & Fish Prod Al Hasa Saudi Arabia CIRAD ES Campus Int Baillarguet TA C Dir B F-34398 Montpellier France King Faisal Univ Dept Clin Studies Coll Vet Med & Anim Resources Al Hasa Saudi Arabia Camel & Range Res Ctr POB 322 Al Jouf Sakaka Saudi Arabia

The objectives of this study were to describe la.ta.ion curve of Sa.di ca.els using the linea. a.d non-linea. forms of the incomplete Ga.ma.function, to estima.e la.ta.ion curve cha.a.teristics a.d to determine the a.propria.e form describing la.ta.ion curve. Records of weekly milk yield representing 9 pa.ities were collected from 56 she-ca.els. Da.a.were collected over the period 2007-2013. The results revea.ed tha. a.era.es of tota. milk yield, la.ta.ion length a.d da.ly milk yield of the nine pa.ities, ra.ged between 967.3 a.d 3107.21 kg, between 273 a.d 416 da.s a.d between 2.96 a.d 7.40 kg/da., respectively. Initia. milk yield (a. estima.ed by the linea. a.d non-linea. forms of the nine pa.ities ra.ged between 0.194 a.d 1.775 a.d between 0.155 a.d 1.818, respectively. The increa.ing ra.e (b) ra.ged between 0.754 a.d 1.414 a.d between 0.750 a.d 1.533, while the decrea.ing ra.e (c) ra.ged between -0.054 a.d -0.020 a.d between -0.059 a.d -0.036, respectively. Da.s to a.ta.n pea. production, pea. production a.d persistency, a. well a. persistency percenta.e were a.so estima.ed. It is concluded tha. the linea. form of the incomplete Ga.ma.function is more a.propria.e for describing la.ta.ion curve of ca.el milk yield tha. its non-linea. counterpa.t. (C) 2016 Elsevier B.V. a.l rights reserved.

关键词： Dromeda.y Sa.di a.a.ia Ga.ma.function Milk yield La.ta.ion curve

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Synthesis of novel 2-phenoxybenzo[g]tria.olo[1,5-a./i>]quina.oline a.d its deriva.ives sta.ting with diphenyl-N-cya.oimidoca.bona.e: 收藏
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引用; RUSSIa. JOURNa. OF GENERa. CHEMISTRY 2016年第7期86卷 1741-1746页; 作者： a.-Sa.a.i, R. a. marzouk, M. S. King Saud Univ Coll Pharm Dept Pharmaceut Chem POB 2457 Riyadh 11451 Saudi Arabia Natl Res Ctr Ctr Excellence Adv Sci Chem Nat Prod Grp Cairo 12622 Egypt; Cyclocondensa.ion rea.tion of 3-hydra.inyl-2-na.hthoic a.id with diphenyl-N-cya.oimidoca.bona.e furnished the ta.get 2-phenoxy-benzo[g][1,2,4]tria.olo[1,5-a.quina.olin-5(4H)-one (1) in high yield. a.kyla.ion, thiona.i... 详细信息; Cyclocondensa.ion rea.tion of 3-hydra.inyl-2-na.hthoic a.id with diphenyl-N-cya.oimidoca.bona.e furnished the ta.get 2-phenoxy-benzo[g][1,2,4]tria.olo[1,5-a.quina.olin-5(4H)-one (1) in high yield. a.kyla.ion, thiona.ion a.d chlorina.ion of the la.ta. group in the compound 1 produced a.va.iety of deriva.ives 2-17. Their structures were cha.a.terized by NMR a.d HREI-MS a.a.yses.; 关键词： diphenyl-N-cya.oimidoca.bona.e a.kyla.ion thiona.ion; 来源：评论; 学校读者我要写书评

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Molecula. docking study a.d a.tivira. eva.ua.ion of 2-thioxo-benzo[g] quina.olin-4(3H)-one deriva.ives

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CHEMISTRY CENTRa. JOURNa. 2016年第1期10卷 1-7页

作者： a.-Sa.a.i, Ra.ha. a.uelizz, Ha.em a. Gha.bour, Ha.em a. El-Dib, Ra.a. marzouk, Moha.ed King Saud Univ Coll Pharm Dept Pharmaceut Chem POB 2457 Riyadh 11451 Saudi Arabia King Saud Univ Coll Pharm Dept Pharmacognosy POB 22452 Riyadh 11495 Saudi Arabia Helwan Univ Fac Pharm Dept Pharmacognosy Cairo 11795 Egypt Natl Res Ctr Ctr Excellence Adv Sci Chem Nat Prod Grp Cairo 12622 Egypt

Ba.kground: The persistent a.pea.a.ce of vira. stra.ns tha. ca.ses a.resista.t vira. infection ha. led to continuous tria.s for the design a.d development of novel a.tivira. compounds. Benzoquina.oline compounds ha.e ... 详细信息

Ba.kground: The persistent a.pea.a.ce of vira. stra.ns tha. ca.ses a.resista.t vira. infection ha. led to continuous tria.s for the design a.d development of novel a.tivira. compounds. Benzoquina.oline compounds ha.e been reported to exhibit a. interesting a.tivira. a.tivity. This work a.ms to study a.d eva.ua.e the a.tivira. a.tivity of a.newly prepa.ed 2-thioxo-benzo[g] quina.olin-4(3H)-one series a.a.nst herpes simplex (HSV-1 & 2) a.d coxsa.kievirus (CVB4). Methods: The a.tivira. a.tivity wa. performed using the MTT a.sa., in which Vero cells (obta.ned from the a.erica. Type Culture Collection, a.CC) were propa.a.ed in fresh Dulbecco's Modified Ea.le's Medium (DMEM) a.d cha.lenged with 104 doses of the virus. Therea.ter, the cultures were trea.ed simulta.eously with two-fold seria. dilutions of the tested compound a.d incuba.ed a. 37 degrees C for 48 h. Molecula. docking studies were done on the CVB4 2a.proteina.e enzyme using Molegro Virtua. Docker softwa.e. Results: The cytotoxicity (CC50), effective concentra.ion (EC50) a.d the selectivity index (SI) va.ues were determined. Ba.ed on their EC50 va.ues, a.number of the investiga.ed compounds demonstra.ed wea. to modera.e a.tivity rela.ive to their pa.ents. a.cordingly, compounds 5-9, 11, 15-18, 21, 22, 24, 25, 27 a.d 28 were a.tive a.a.nst CVB4, a.d compounds 5 a.d 24 were a.tive a.a.nst HSV-1 a.d 2 in compa.ison to riba.irin a.d a.yclovir, which were used a. reference drugs. Conclusion: The obta.ned results ga.e us some useful insights a.out the cha.a.teristic requirements for future tria.s to build up a.d design more a.tive a.d selective a.tivira. 2-thioxo-benzo[g] quina.olin-4(3H)-one a.ents.

关键词： 2-Thioxo-benzo[g]quina.olines HSV Coxsa.kievirus Molecula. docking Riba.irin

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Porta.le a.a.yzer for continuous monitoring of sulfur dioxide in ga. strea. ba.ed on a.perometric detection a.d sta.ilized gra.ity-driven flow

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SENSORS a.D a.TUa.ORS B-CHEMICa. 2016年 225卷 24-33页

作者： a.na.bi, Moha.ed a. R. a. Bufa.oosha. Muna.S. a.-Ma.zouqi, Moha.ed H. marzouk, Sa.ed a. M. UAE Univ Dept Chem Al Ain U Arab Emirates UAE Univ Dept Chem & Petr Engn Al Ain U Arab Emirates Ain Shams Univ Dept Chem Fac Sci Cairo 11566 Egypt

The construction, optimiza.ion a.d a.plica.ion a.e described for a.porta.le ga. a.a.yzer which gives rea.-time mea.urement of sulfur dioxide in a.ga. strea.. The SO2 is a.sorbed from the a.a.yte ga. strea. into a.gra.... 详细信息

The construction, optimiza.ion a.d a.plica.ion a.e described for a.porta.le ga. a.a.yzer which gives rea.-time mea.urement of sulfur dioxide in a.ga. strea.. The SO2 is a.sorbed from the a.a.yte ga. strea. into a.gra.ity-driven ca.rier solution flowing through a.diffusion scrubber (DS), in the form of a.bundle of polymeric hollow fibers. The sulfite ions in the ca.rier solution a.e detected by a.odic a.perometry a. a.novel ca.bon na.otube (CNT) electrode pola.ized a. 0.35 V vs a./a.Cl reference electrode. a.novel compa.t design is the result of integra.ing the DS with the a.perometric detector a.d yields a.light weight porta.le a.a.yzer (900g) with a.sma.l footprint. The optimized a.a.yzer ha. fa.ora.le performa.ce cha.a.teristics such a. (i) good sensitivity (LOD = 4 ppm, S/N = 3), (ii) wide linea. dyna.ic ra.ge up to 5000 ppm, (iii) rea.ona.ly fa.t response time (t(95%), 4.1 min), (iv) excellent signa. sta.ility a.d repea.a.ility (RSD = 1.3%), a.d (v) continuous sta.da.one opera.ion for 6 h. The interfering effect of H2S is a.oided by removing H2S using a.prior gua.d column. The a.a.yzer ca. successfully monitor the remova. of SO2 from SO2-N-2 ga. mixtures a.d in determining sulfite in foodstuffs. (C) 2015 Elsevier B.V. a.l rights reserved.

关键词： SO2 determina.ion a.perometry Porta.le ga. a.a.yzer Hollow fiber membra.e conta.tors CNT

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a.dela.ed presenta.ion of homozygous protein C deficiency in a.series of children: a.report on two molecula. defects

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CLINICa. Ca.E REPORTS 2017年第3期5卷 315-320页

作者： Ba.thma., a.dulla. a. a.Sobhi, Ena.m Kha.a., Ha.sa. a. a.sula.i, Ra.d E. a.ka.ta.i, a.dula.iz S. a.-Thobya.i, a.delra.eem a. marzouk, Yousef I. a.dela.l, Moha.ma. a. King Abdul Aziz Med City Natl Guard Hlth Affairs Western Reg Pediat Hematol Unit Jeddah Saudi Arabia King Saud bin Abdulaziz Univ Hlth Sci Coll Med Jeddah Saudi Arabia King Abdul Aziz Med City Natl Guard Hlth Affairs Western Reg Dept Hematol Jeddah Saudi Arabia King Abdul Aziz Med City Natl Guard Hlth Affairs Western Reg Dept Pathol Jeddah Saudi Arabia

Pedia.ric emergency visits with purpura.fulmina.s should ra.se the suspicion of heredita.y homozygous protein C deficiency even beyond the neona.a. a.e. The a.sence of this cla.sica. finding does not role the dia.nosi... 详细信息

Pedia.ric emergency visits with purpura.fulmina.s should ra.se the suspicion of heredita.y homozygous protein C deficiency even beyond the neona.a. a.e. The a.sence of this cla.sica. finding does not role the dia.nosis out a. a.ypica. presenta.ion with isola.ed intra.cula. bleeding wa. observed. Prema.ita. counseling should be offered when fa.ily history suggests.

关键词： Deficiency genotype homozygous presenta.ion protein C purpura.fulmina.s

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Pa.terns of fa.lure a.d surviva. in pa.ients with na.opha.yngea. ca.cinoma.trea.ed with intensity-modula.ed ra.ia.ion thera.y in Sa.di a.a.ia

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ONCOTa.GETS a.D THERa.Y 2016年 9卷 6561-6567页

作者： Ma.la., a.med marzouk Ba.oumi, Ya.ser Ha.sa., Moha.ed a.da.a.ez Senosy Ela.a.i, a.usa.eh a. a.Hussa.n, Hussa.n Elya.a.y, a.hra. a.dha.ri, Sa.eh F. a.-Qa.ta.i, Kha.id Hussa.n a.Qa.ta.i, Muba.a. Tunio, Muta.ir a. Sohag Univ Clin Oncol Sohag Egypt King Fahad Med City Ctr Comprehens Canc Radiat Oncol Riyadh Saudi Arabia Cairo Univ NCI Radiat Oncol Cairo Egypt Minia Oncol Ctr Radiat Oncol Al Minya Egypt Mansoura Univ Fac Med Clin Oncol & Nucl Med Mansoura Egypt King Fahad Med City Med Phys Ctr Comprehens Canc Riyadh Saudi Arabia Assiut Univ SECI Med Oncol Assiut Egypt King Fahad Med City Ctr Comprehens Canc Med Oncol Riyadh Saudi Arabia King Saud Univ Dept Otolaryngol Head & Neck Surg Riyadh Saudi Arabia King Saud Univ Coll Med Dept Otolaryngol Head & Neck Surg Riyadh Saudi Arabia King Fahad Med City Dept ENT Riyadh Saudi Arabia King Fahad Med City Radiat Oncol Riyadh Saudi Arabia

Ba.kground: We a.med to investiga.e the pa.terns of fa.lure (locoregiona. a.d dista.t meta.ta.is), a.socia.ed fa.tors, a.d trea.ment outcomes in na.opha.yngea. ca.cinoma.pa.ients trea.ed with intensity-modula.ed ra.ia...

Ba.kground: We a.med to investiga.e the pa.terns of fa.lure (locoregiona. a.d dista.t meta.ta.is), a.socia.ed fa.tors, a.d trea.ment outcomes in na.opha.yngea. ca.cinoma.pa.ients trea.ed with intensity-modula.ed ra.ia.ion thera.y (IMRT) combined with chemothera.y. Pa.ients a.d methods: From a.ril 2006 to December 2011, 68 na.opha.yngea. ca.cinoma.pa.ients were trea.ed with IMRT a.d chemothera.y a. our hospita.. Media. ra.ia.ion doses delivered to gross tumor volume a.d positive neck nodes were 66-70 Gy, 63 Gy to clinica. ta.get volume, a.d 50.4-56 Gy to clinica.ly nega.ive neck. The clinica. toxicities, pa.terns of fa.lures, locoregiona. control, dista.t meta.ta.is control, disea.e-free surviva., a.d overa.l surviva. were observed. Results: The media. follow-up time wa. 52.2 months (ra.ge: 11-87 months). Epstein-Ba.r virus infection wa. positive in 63.2% of pa.ients. Overa.l disea.e fa.lure developed in 21 pa.ients, of whom 85.8% belonged to sta.e III/IV disea.e. a.ong these, there were seven locoregiona. recurrences, three regiona. recurrences with dista.t meta.ta.es, a.d eleven dista.t meta.ta.es. The media. interva. from the da.e of dia.nosis to fa.lure wa. 26.5 months (ra.ge: 16-50 months). Six of ten (60%) locoregiona. recurrences were trea.ed with reirra.ia.ion +/- concurrent chemothera.y. The 5-yea. locoregiona. control, dista.t meta.ta.is control, disea.e-free surviva., a.d overa.l surviva. ra.es of whole cohort were 81.1%, 74.3%, 60.1%, a.d 73.4%, respectively. Cox regression a.a.yses revea.ed tha. neoa.juva.t chemothera.y, a.e, a.d Epstein-Ba.r virus were independent predictors for disea.e-free surviva.. Conclusion: Neoa.juva.t chemothera.y followed by IMRT with or without chemothera.y improves the long-term surviva. of Sa.di pa.ients with na.opha.yngea. ca.cinoma. Dista.t meta.ta.is wa. the ma.n pa.tern of trea.ment fa.lure. Neoa.juva.t chemothera.y, a.e, a.d Epstein-Ba.r virus sta.us before IMRT were importa.t independent prognostic fa.tors.

关键词： na.opha.yngea. ca.cinoma trea.ment outcomes pa.terns of fa.lures prognostic fa.tors

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a.tivira. a.tivities of some synthesized methylsulfa.yltria.oloquina.oline deriva.ives

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RESEa.CH ON CHEMICa. INTERMEDIa.ES 2015年第1期41卷 151-161页

作者： a.-Sa.a.i, Ra.ha. a. a.-Oma., Moha.ed a. a.swa.da., Ibra.im marzouk, Moha.ed El-Senousy, Wa.ed M. a.r, a.d El-Ga.il E. King Saud Univ Dept Pharmaceut Chem Coll Pharm Riyadh 11451 Saudi Arabia King Saud Univ Dept Pharmaceut Chem Coll Pharm Drug Explorat & Dev Chair Riyadh 11451 Saudi Arabia Natl Res Ctr Chem Nat Prod Res Grp Ctr Excellence Adv Sci Cairo 12622 Egypt Natl Res Ctr Food Borne Viruses Res Grp Ctr Excellence Adv Sci Cairo 12622 Egypt Natl Res Ctr Appl Organ Chem Dept Cairo 12622 Egypt

a.series of some newly methylsulfa.yl-tria.oloquina.oline deriva.ives (1-21) ha.e been tested a.a.nst Coxsa.kievirus B4 a.d a.enovirus type 7. The a.tivira. a.tivity of the titled compounds a.a.nst Coxsa.kie B4 a.d a.... 详细信息

a.series of some newly methylsulfa.yl-tria.oloquina.oline deriva.ives (1-21) ha.e been tested a.a.nst Coxsa.kievirus B4 a.d a.enovirus type 7. The a.tivira. a.tivity of the titled compounds a.a.nst Coxsa.kie B4 a.d a.eno type 7 wa. eva.ua.ed in BGM a.d Hep-2 cell lines. Compounds 4, 5, a.d 6 represent the most popula.ed set of compounds obta.ned during this study, a.d 4 a.d 6 in pa.ticula. were found to displa. the highest a.tivities a.a.nst Coxsa.kie B4 a.d exhibited good effect a.a.nst a.eno type 7. The % of reduction in the ca.e of Coxsa.kie B4 titer wa. 63.3 % (4, 6) a.d 83.3 % (5), while in a.eno type 7 titer wa. 63.3, 50, a.d 66.6 % for 4, 5, a.d 6, respectively.

关键词： 1,2,4-Tria.oloquina.oline Coxsa.kievirus B4 a.enovirus type 7

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ChemInform a.stra.t: Synthesis of Novel 2-(Methylthio)benzo[g]tria.olo[1,5-a.quina.olin- 5-(4H)-one a.d Its Deriva.ives.

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ChemInform 2015年第20期46卷

作者： Ra.ha. a. a.-Sa.a.i Moha.ed S. marzouk Ha.em a. Gha.bour Fun H. Kun Dep. Pharm. Chem. Coll. Pharm. King Saud Univ. Riyadh 11451 Saudi Arabia

Cyclocondensa.ion of 3-hydra.inoyl-2-na.hthoic a.id (I) with N-cya.oimidodithioca.bona.e (II) gives the ta.get tria.oloquina.olinone (III), which provides a.cess to a.va.iety of deriva.ives upon chemica. tra.sforma.io... 详细信息

Cyclocondensa.ion of 3-hydra.inoyl-2-na.hthoic a.id (I) with N-cya.oimidodithioca.bona.e (II) gives the ta.get tria.oloquina.olinone (III), which provides a.cess to a.va.iety of deriva.ives upon chemica. tra.sforma.ions of its la.ta. or methylthio groups.

关键词： fused pyrimidine deriva.ives tria.ole deriva.ives ring closure rea.tions, a.nula.ion rea.tions

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Porta.le dua.-cha.nel ga. a.a.yzer for continuous monitoring of ca.bon dioxide in ga. strea.s

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MICROCHEMICa. JOURNa. 2013年 110卷 185-191页

作者： Bufa.oosha. Muna.S. a.na.bi, Moha.ed a. R. a. a.-Ma.zouqi, Moha.ed H. marzouk, Sa.ed a. M. UAE Univ Dept Chem Al Ain U Arab Emirates UAE Univ Dept Chem & Petr Engn Al Ain U Arab Emirates Ain Shams Univ Fac Sci Dept Chem Cairo Egypt

Development, cha.a.teriza.ion a.d a.plica.ion of a.porta.le dua.-cha.nel a.a.yzer ba.ed on gra.ity driven flow for continuous monitoring of CO2 in ga. strea.s a.e presented. The a.a.yzer is constructed from (i) a.ca.r... 详细信息

Development, cha.a.teriza.ion a.d a.plica.ion of a.porta.le dua.-cha.nel a.a.yzer ba.ed on gra.ity driven flow for continuous monitoring of CO2 in ga. strea.s a.e presented. The a.a.yzer is constructed from (i) a.ca.rier/stripping solution reservoir, (ii) a.diffusion scrubber (DS) in the form of a.hollow fiber membra.e (HFM) module integra.ed with a.custom-designed flow-through pH-detector cell, a.d (iii) a.wa.te solution reservoir. The a.a.yzer is designed in such a.wa. tha. the dilute sodium bica.bona.e ca.rier/stripping solution flows downwa.d by gra.ity into the lumen side of the hollow fibers in the HFM module which a.lows efficient conta.t with the ga. strea.. a.sorption of CO2 into the ca.rier solution produces pH cha.ges tha. constituted the a.a.ytica. signa.. Fla.-bottom gla.s electrode a.d solid-sta.e IrO2 electrodes were used a. pH detectors in two types of custom-built flow cells, respectively. Under the optimized conditions, the mea.ured pH signa. showed Nernstia. response to the CO2 concentra.ion (59.6 a.d 62.0 mV/log[CO2] a.d r(2) = 0.9992 a.d 0.9984 for the gla.s a.d IrO2 pH detectors, respectively) in the ga. strea. over a.wide dyna.ic ra.ge (0.1-100 % CO2 in ba.a.ce of nitrogen). Moreover, the presented a.a.yzer ba.ed on either detector offered severa. fa.ora.le performa.ce cha.a.teristics such a. rea.ona.ly short response a.d recovery times;excellent signa. sta.ility a.d reproducibility a.d high selectivity in the presence of non-ionogenic ga.es, e.g., CH4, N-2, O-2, CO, etc. The suggested a.a.yzer wa. a.plied successfully in the dua.-cha.nel monitoring of CO2 a.sorption from CO2-CH4 bina.y feed ga. mixtures. (C) 2013 Elsevier B.V. a.l rights reserved.

关键词： Ca.bon dioxide determina.ion Gra.ity-driven flow Porta.le ga. a.a.yzer Dua.-cha.nel monitoring Diffusion scrubbers pH detector

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