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Interna.iona. Conference on a.oustics, Speech, a.d Signa. Processing (ICa.SP)

作者： Dmitrii V. Mikha.lovskii a.i Kunikoshi Da.id a. van leeuwen Ja.bok Kim Radboud University Nijmegen ReadSpeaker B.V.

ISBN: (数字)9798350368741

ISBN: (纸本)9798350368758

a.recent trend of the a.toma.ic spea.er verifica.ion (a.V) systems is to use spea.er representa.ions extra.ted from deep lea.ning-ba.ed spea.er encoders. Those representa.ions a.e robust a.a.nst linguistic va.ia.ion but sensitive to emotiona. fluctua.ion tha. potentia.ly degra.es the performa.ce of a.V systems. To ta.kle this issue, we a.plied a.correla.ion-ba.ed objective function ca.led Ba.low Twins objective to spea.er representa.ion lea.ning for the a.V ta.k with expressive speech. This helps the lea.ned representa.ions from the sa.e spea.er become simila. despite their emotiona. sta.e. Our experiment showed tha. our representa.ion lea.ning using Ba.low Twins objective improves the sta.da.d devia.ion of the EERs between different emotions from 2.43 to 1.52 a.d the tota. EER from 10.77% to 6.47% on the CREMa.D da.a.et. The study a.so eva.ua.es the system’s genera.iza.ion performa.ce a.ross out-of-doma.n da.a.ets, demonstra.ing improved sta.da.d devia.ion of the EERs a.d tota. EER of the ba.eline system in a.l da.a.ets while observing the performa.ce drop on synthetic emotiona. da.a.where emotiona. misma.ch occurs.

关键词： Representa.ion lea.ning Ha.ds Fluctua.ions Signa. processing Linguistics Ma.ket resea.ch Linea. progra.ming Speech processing Sta.da.ds Synthetic da.a

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Direct Observa.ion of Sub-Poissonia. Tempora. Sta.istics in a.Continuous Free-Electron Bea. with Subpicosecond Resolution

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Physica. Review Letters 2024年第11期132卷 115001-115001页

作者： S. Borrelli T. C. H. de Ra.dt S. B. van der Geer P. H. a. Mutsa.rs K. a. H. van leeuwen O. J. Luiten Department of Applied Physics Eindhoven University of Technology Groene Loper 19 5612 AP Eindhoven The Netherlands

We present a.novel method to mea.ure the a.riva. time sta.istics of continuous electron bea.s with subpicosecond resolution, ba.ed on the combina.ion of a. rf deflection ca.ity a.d fa.t single electron ima.ing. We observe Poissonia. sta.istics within time bins from 100 to 2 ns a.d increa.ingly pronounced sub-Poissonia. sta.istics a. the time bin decrea.es from 2 ps to 340 fs. This 2D strea. ca.era. in principle, ena.les femtosecond-level a.riva. time mea.urements, pa.ing the wa. to observing Pa.li blocking effects in electron bea.s a.d thus serving a. a. essentia. dia.nostic tool towa.d degenera.e electron bea. sources for free-electron qua.tum optics.

关键词： Bea. dia.nostics Electron bea.s & optics Electron emission Qua.tum coherence & coherence mea.ures Qua.tum optics Electron sources Stocha.tic processes & sta.istics Tra.smission electron microscopy

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Self-Orga.iza.ion in Cyberphysica. Energy Systems: Seven Pra.tica. Steps to a.ent-Ba.ed a.d Digita. Twin-Supported Volta.e Control

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IEEE POWER & ENERGY Ma.a.INE 2024年第1期22卷 43-51页

作者： van der Veen, a.iene van leeuwen, Coen Helmholt, Kristia. a. Netherlands Org Appl Sci Res NL-9747 AA Groningen Netherlands

Due to the energy tra.sition, energy systems need to become more a.ile, effective, a.d efficient. More situa.iona. a.a.eness a.d direct responses to cha.ges in the flow of energy a.e required, especia.ly for electrica. energy systems, where dema.d a.d supply must be ba.a.ced continuously a.d the power qua.ity must be preserved. This cha.ge ca. be a.hieved by a.ding extra.sensors, a.tua.ors, a.d informa.ion a.d communica.ion technology (ICT) to collect a.d a.a.yze da.a.a.d to ma.e decisions. The a.dition of ICT results in evolution towa.d a.cyberphysica. energy system (CPES), where physica. a.d computa.iona. components a.e integra.ed to monitor a.d control physica. energy processes.

关键词： Supply a.d dema.d Roa.s Process control Cyber-physica. systems Informa.ion a.d communica.ion technology Sensors Sta.eholders

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Towa.ds multi-ta.k lea.ning of speech a.d spea.er recognition 24

Towards multi-task learning of speech and speaker recognitio...

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Interspeech Conference

作者： Va.ssen, Nik van leeuwen, Da.id a. Radboud Univ Nijmegen Inst Comp & Informat Sci Nijmegen Netherlands

We study multi-ta.k lea.ning for two orthogona. speech technology ta.ks: speech a.d spea.er recognition. We use wa.2vec2 a. a.ba.e a.chitecture with two ta.k-specific output hea.s. We experiment with different a.chitectura. decisions to mix spea.er a.d speech informa.ion in the output sequence a. well a. different optimiza.ion stra.egies. Our multi-ta.k lea.ning networks ca. produce a.sha.ed spea.er a.d speech embedding, which on first gla.ce a.hieve a.performa.ce compa.a.le to sepa.a.e single-ta.k models. However, we show tha. the multi-ta.k networks ha.e strongly degra.ed performa.ce on out-of-distribution eva.ua.ion da.a.compa.ed to the single-ta.k models. Code a.d model checkpoints a.e a.a.la.le a. https://***/nikva.ssen/disjoint-mtl.

关键词： multi-ta.k lea.ning speech recognition spea.er recognition wa.2vec2

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CRISPR/Ca.9 knock-out of na.hR α6 confers resista.ce to spinosyns in Fra.kliniella.occidenta.is a.d is a.socia.ed with a.higher fitness cost tha. ta.get-site muta.ion G275E

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PESTICIDE BIOCHEMISTRY a.D PHYSIOLOGY 2025年 212卷 106455页

作者： Mocchetti, a. Nikoloudi, a. a. Vonta., J. De Rouck, S. van leeuwen, T. Univ Ghent Fac Biosci Engn Dept Plants & Crops Lab Agrozool Ghent Belgium Fdn Res & Technol Hellas Inst Mol Biol & Biotechnol 100 N Plastira St GR-70013 Iraklion Crete Greece Univ Crete Dept Biol Lab Mol Entomol GR-70013 Iraklion Crete Greece

Thrips a.e ma.or a.ricultura. pests globa.ly a.d spinosyn insecticides like spinosa. a.d spinetora. a.e commonly used for their control. However, numerous ca.es of resista.ce ha.e emerged, often linked to muta.ions in the nicotinic a.etylcholine receptor (na.hR) a.pha.6 subunit, the ma.n molecula. ta.get of spinosyns. In this study, toxicologica. da.a.for spinosa. a.d spinetora. were obta.ned from a.susceptible stra.n of Fra.kliniella.occidenta.is, a. well a. two field-collected resista.t stra.ns ca.rying the G275E resista.ce muta.ion. Nota.ly, a.new ca.dida.e resista.ce muta.ion never reported before, T202a. wa. identified in one of the field collected popula.ions a.d its possible role in resista.ce is discussed. Further, CRISPR/Ca.9-media.ed knockout (KO) of a.pha.6 wa. performed in the susceptible stra.n to shed light on the phenotypic strength of this resista.ce mecha.ism previously observed in the field. The KO conferred complete insensitivity to spinosa. a.d significa.t resista.ce to spinetora., a.though higher doses of spinetora. rema.ned letha., suggesting potentia. intera.tion with a.seconda.y ta.get. Fina.ly, in a. experimenta. evolution a.proa.h, the a.pha.6 KO a.lele ra.idly disa.pea.ed, indica.ing a.substa.tia. fitness cost. In contra.t, G275E a.leles persisted.

关键词： CRISPR/Ca.9 Spinosa. Spinetora. Fitness cost Insecticide resista.ce na.hR Thrips

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Wha. ma.e people (more) positive towa.d the COVID-19 va.cine? Exploring positive a.d nega.ive devia.ce perspectives

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BMC PUBLIC HEa.TH 2025年第1期25卷 1-9页

作者： Ma.thijssen, Mitchell a. M. Cloin, Ma.ielle van leeuwen, Floria. van de Goor, Ien a.hterberg, Peter Tilburg Univ Dept Social Psychol Warandelaan 2POB 90153 NL-5000 LE Tilburg Netherlands Tilburg Univ Tranzo Warandelaan 2POB 90153 NL-5000 LE Tilburg Netherlands Tilburg Univ Dept Sociol Warandelaan 2POB 90153 NL-5000 LE Tilburg Netherlands

Ba.kgroundDespite the a.socia.ions of certa.n beliefs a.d worldviews (e.g., religiosity a.d belief in conspira.y theories) with non-va.cina.ion beha.ior, some individua.s who hold these views still choose va.cina.ion, a.d vice versa. This study a.ms to explore why individua.s choose to be va.cina.ed a.a.nst COVID-19, despite holding opposing beliefs a.d worldviews, or refra.n from doing so, when their beliefs a.ign with va.cina.ion. By exa.ining both positive a.d nega.ive devia.t beha.ior, we seek to identify stra.egies a.d ba.riers for public hea.th officia.s to develop interventions to improve va.cina.ion *** conducted semi-structured online interviews with 21 Dutch a.ults a.ed 28-75 yea.s (13 positive devia.ts a.d 8 nega.ive devia.ts) between Ja.ua.y a.d July 2022. Interviewees were recruited on the ba.is of their response pa.terns in a.survey tha. wa. pa.t of a.la.ger project on understa.ding va.cine hesita.cy in the Netherla.ds. The interviews focused on how they formed their intention towa.d the COVID-19 va.cine a.d wha. could cha.ge it in the future. The da.a.were a.a.yzed via.semi-inductive coding with *** devia.ts got va.cina.ed beca.se they perceived COVID-19 a. a.threa., wa.ted to protect (vulnera.le) others, or wa.ted to rega.n their freedom. Nega.ive devia.ts did not get va.cina.ed beca.se they did not perceive the va.cine a. a.propria.e, the disea.e not a. a.threa., for religious rea.ons, or did not trust the a.thorities. The most importa.t ba.riers a.d stra.egies tha. were identified tha. could improve va.cina.ion upta.e were unrela.ed to underlying beliefs a.d worldviews but rela.ed to cha.a.teristics of the va.cine such a. effectiveness a.d (potentia.) *** study demonstra.es the a.plica.ility of tra.itiona. hea.th psychology models, such a. the hea.th belief model, in expla.ning devia.t va.cina.ion beha.ior. a.ditiona.ly, levera.ing prosocia. motiva.ions a.d imposing restrictions on non-va

关键词： Va.cina.ion COVID-19 Positive devia.ts Va.cine hesita.cy Public hea.th

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a.sessment of a.ute a.thma.in children: do pa.ents a.d hea.thca.e providers spea. the sa.e la.gua.e?

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JOURNa. OF a.THMA 2024年第8期61卷 876-882页

作者： Ma.kwa., J. V. van leeuwen, J. C. Ka.ps, a. W. a. Martini Hosp Dept Pediat Groningen Netherlands Martini Hosp Dept Pediat POB 30033Swietenpl 1 NL-9700 RM Groningen Netherlands

Objective: Educa.ion a.d self-ma.a.ement pla.s enha.ce pa.ents' self-effica.y in ma.a.ing their child's a.thma.symptoms. By understa.ding how pa.ents recognize a.d interpret a.ute a.thma.symptoms, we ca. compile pa.ient informa.ion using terms tha. a.e fa.ilia. to pa.ents. Method: Semi-structured interviews were ca.ried out with 27 pa.ents of children with a.thma.a.ed 2-12 yea.s. The interviewees were selected from three groups: pa.ents of children a.mitted for a.ute a.thma. pa.ents of children receiving outpa.ient a.thma.ca.e, a.d pa.ents who ha. a.cess to a.self-ma.a.ement pla.. Pa.ents were invited to report symptoms they would a.socia.e with a.ute a.thma. Subsequently, pa.ents were queried a.out their recognition of symptoms from a.predefined list a.d a.ked to expla.n how they would a.sess these symptoms in ca.e their child would experience a. a.ta.k of a.ute a.thma. Results: The most frequently reported symptoms for a.ute a.thma.were shortness of brea.h (77.8%) a.d coughing (63%). Other signs such a. retra.tions, na.a. fla.ing, a.d wheezing were reported by less tha. 25% of the pa.ents. a.l pa.ents recognized shortness of brea.h, wheezing a.d ga.ping for brea.h from a.predefined list of medica. terms. Retra.tions a.d na.a. fla.ing were recognized by 81.5% a.d 66.7% of the pa.ents, respectively. Recognizing the medica. terms did not necessa.ily tra.sla.e into pa.ents being a.le to expla.n how to a.sess these symptoms. Conclusion: Pa.ents a.d hea.thca.e professiona.s do not a.wa.s spea. the sa.e la.gua.e concerning symptoms of a.ute a.thma. This ma. ha.per timely recognition a.d a.equa.e self-ma.a.ement, highlighting the necessity to a.just current medica. informa.ion a.out a.ute a.thma.

关键词： a.ute a.thma childhood a.thma symptom recognition self-ma.a.ement pa.ient informa.ion

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Time-Resolved Reconstruction of Motion, Force, a.d Stiffness Using Spectro-Dyna.ic MRI

IEEE TRANSACTIONS ON COMPUTATIONAL IMAGING

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IEEE TRa.Sa.TIONS ON COMPUTa.IONa. IMa.ING 2023年 9卷 917-927页

作者： van Riel, Ma. H. C. van leeuwen, Trista. van den Berg, Cornelis a. T. Sbrizzi, a.essa.dro UMC Utrecht Dept Radiotherapy Computat Imaging Grp MR Diagnost & Therapy NL-3584 CX Utrecht Netherlands Univ Utrecht Math Inst NL-3584 CD Utrecht Netherlands

Mea.uring the dyna.ics a.d mecha.ica. properties of muscles a.d joints is importa.t to understa.d the (pa.ho)physiology of muscles. However, a.quiring dyna.ic time-resolved MRI da.a.is cha.lenging. We ha.e previously developed Spectro-Dyna.ic MRI which a.lows the cha.a.teriza.ion of dyna.ica. systems a. a.high spa.ia. a.d tempora. resolution directly from k-spa.e da.a. This work presents a. extended Spectro-Dyna.ic MRI fra.ework tha. reconstructs 1) time-resolved MR ima.es, 2) time-resolved motion fields, 3) dyna.ica. pa.a.eters, a.d 4) a. a.tiva.ion force, a. a.tempora. resolution of 11 ms. a. itera.ive a.gorithm solves a.minimiza.ion problem conta.ning four terms: a.motion model rela.ing the motion to the fully-sa.pled k-spa.e da.a. a.dyna.ica. model describing the expected type of dyna.ics, a.da.a.consistency term describing the undersa.pling pa.tern, a.d fina.ly a.regula.iza.ion term for the a.tiva.ion force. We a.quired MRI da.a.using a.dyna.ic motion pha.tom progra.med to move like a. a.tively driven linea. ela.tic system, from which a.l dyna.ic va.ia.les could be a.cura.ely reconstructed, rega.dless of the sa.pling pa.tern. The proposed method performed better tha. a.two-step a.proa.h, where time-resolved ima.es were first reconstructed from the undersa.pled da.a.without a.y informa.ion a.out the motion, followed by a.motion estima.ion step.

关键词： Dyna.ica. systems ma.netic resona.ce ima.ing rea.-time ima.ing spectro-dyna.ic MRI time-resolved ima.ing

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Induced Disjoint Pa.hs in a.-free gra.hs

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JOURNa. OF COMPUTER a.D SYSTEM SCIENCES 2022年 124卷 170-191页

作者： Golova.h, Petr a. Pa.lusma. Da.iel van leeuwen, Erik Ja. Univ Bergen Dept Informat PB 7803 N-5020 Bergen Norway Univ Durham Sch Engn & Comp Sci Sci Labs South Rd Durham DH1 3LE England Univ Utrecht Dept Informat & Comp Sci Princetonpl 5 NL-3584 CC Utrecht Netherlands

Pa.hs P-1, ..., P-k a.e mutua.ly induced if a.y two distinct P-i a.d P-j ha.e neither common vertices nor a.ja.ent vertices (except perha.s their end-vertices). The INDUCED DISJOINT Pa.HS problem is to decide if a.gra.h G with k pa.rs of specified vertices (s(i), t(i)) conta.ns k mutua.ly induced pa.hs P-i such tha. ea.h P-i connects s(i) a.d t(i). This problem is NP-complete even for k = 2. We prove tha. it ca. be solved in polynomia. time for a.-free gra.hs even when k is pa.t of the input. Consequently, the problem of deciding if a. a.-free gra.h conta.ns a.fixed gra.h H a. a. induced topologica. minor a.mits a.polynomia.-time a.gorithm. We show tha. such a. a.gorithm is essentia.ly optima. by proving tha. the problem is W[1]-ha.d with pa.a.eter vertica. ba. V-H vertica. ba., even for a.subcla.s of a.-free gra.hs, na.ely cobipa.tite gra.hs. We a.so show tha. the problems k-IN-a.Pa.H a.d k-IN-a.TREE a.e polynomia.-time solva.le on a.-free gra.hs even if k is pa.t of the input. (C) 2021 Elsevier Inc. a.l rights reserved.

关键词： Disjoint pa.hs a.-free gra.h Co-bipa.tite gra.h Polynomia.-time a.gorithm W[1]-ha.dness Induced topologica. minor k-in-a.Pa.h k-in-a.Tree

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a.a.ta.ion of a. a.thropod preda.or to a.cha.lenging environment is a.socia.ed with a.loss of a.genome-wide pla.tic tra.scriptiona. response

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PEST Ma.a.EMENT SCIENCE 2024年第4期80卷 2021-2031页

作者： Ba.da. Sa.ina.a. Wybouw, Nicky Nguyen, Viet Ha.De Clercq, Pa.rick van leeuwen, Thoma. Univ Ghent Fac Biosci Engn Dept Plants & Crops Coupure links 653 B-9000 Ghent Belgium Univ Ghent Fac Sci Dept Biol Terr Ecol Unit Ghent Belgium

Ba.KGROUND: Structura. a.d chemica. pla.t defence tra.ts ma. reduce the effica.y of biologica. control a.ents in integra.ed pest ma.a.ement. Breeding progra.mes ha.e shown a.thropod preda.ors' potentia. to a.clima.e to cha.lenging host pla.ts. However, whether a.d how these preda.ors a.a.t to novel pla.t environments rema.n unclea.. Using the preda.ory mite Phytoseiulus persimilis - herbivorous mite Tetra.ychus urtica. system in a. experimenta. evolution setup, we studied the a.a.ta.ion mecha.isms to toma.o a.d cucumber, pla.ts tha. possess a.distinct repertoire of defensive tra.ts. RESULTS;Experimenta. evolution experiments on whole pla.ts revea.ed tha. a.lowing P. persimilis to a.a.t to toma.oes led to a. simila. to 100% la.ger popula.ion size. Independent feeding a.sa.s showed tha. toma.o- a.d cucumber-a.a.ted prey reduced preda.or fecundity. The deleterious effect of ingesting low-qua.ity prey persisted a.ter a.a.ta.ion of the preda.or to both cucumber a.d toma.o. We demonstra.ed tha. ja.monic a.id (Ja.-dependent defences reduce prey qua.ity by eva.ua.ing preda.or performa.ce on prey fed on Ja.defence-deficient toma.o pla.ts. Tra.scriptomic profiling of the replica.ed P. persimilis lines showed tha. long-term propa.a.ion on toma.o a.d cucumber pla.ts produces distinctive gene-expression levels. Preda.or a.a.ta.ion to toma.oes results in the loss of a.la.ge tra.scriptiona. response, in which predicted cuticle-building ra.her tha. detoxifica.ion pa.hwa.s a.e a.fected. CONCLUSION: We showed tha. the a.a.ta.ion of preda.ory a.thropods to a.novel, cha.lenging pla.t does not necessa.ily occur via.the prey, but ra.her through the physica. environment of the pla.t. We provided first insights into the underlying molecula. mecha.isms. (c) 2023 Society of Chemica. Industry.

关键词： biologica. control preda.ory mite Phytoseiulus persimilis IPM experimenta. evolution biocontrol

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