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Autoamputation of the appendix and survival of the amputated part: a rare case report and literature review

BMC SURGERY 2022年第1期22卷 249-249页

作者： Wang, Mingxiang Ning, Shili Liu, Yaqing chen, Zhao Jiang, Haodong Faiz, Shabnam Luo, fuwen Dalian Med Univ Hosp 2 Zhongshan Rd Dalian Liaoning Peoples R China Dalian Med Univ Dept Gen Surg Hosp 2 Zhongshan Rd Dalian 116023 Liaoning Peoples R China

Background Autoamputation of the appendix, i.e., complete separation of a part of the appendix without any surgical intervention, has been rarely documented in the literature in recent years. Herein, we report a case where the amputated part of the appendix was viable after autoamputation and reviewed the related literature. Case presentation A 39-year-old female patient was admitted to our hospital complaining of abdominal pain and subsequently underwent an emergency laparoscopic appendectomy (LA). Intraoperatively, we found an abnormally short appendix protruding from the cecum and a strip-like tissue attached to the mesoappendix, considered a duplex appendix, was resected. Finally, in conjunction with the histopathology findings and the past medical history, the patient was diagnosed with "Pseudo-duplication of the Appendix". Conclusions Autoamputation of the appendix resulting in preserved tissue viability and absence of necrosis at both ends, can be termed as "Pseudo-duplication of the Appendix". This condition is very rare in clinical practice and has not been reported in China, to the best of our knowledge. It has been established that the autoamputated appendix can produce chronic inflammation, intestinal fistulae and even cancer, affecting the patient's quality of life. Accordingly, a clear diagnosis and timely management are essential. In this report, we established a novel classification for "Pseudo-duplication of the Appendix", hoping that our report will help surgeons better understand this anatomical anomaly of the appendix, to help during the differential diagnosis process and avoid confusion.

关键词： Appendix Appendicitis Autoamputation Laparoscopic appendectomy Pseudo-duplication appendix

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深度学习用于肩关节影像学研究进展

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中国医学影像技术 2024年第2期40卷 302-305页

作者：郑喻文武玉花陈晓飞董馥闻王平周晟甘肃中医药大学第一临床医学院甘肃兰州730000 甘肃省中医院放射科甘肃兰州730050 甘肃省人民医院放射科甘肃兰州730000

肩痛在肌肉骨骼疼痛中居第三位,人群患病率较高,早期诊断至关重要。深度学习(DL)技术用于肩关节影像学有利于临床诊治肩部疾病及评估预后。本文对DL技术在肩关节影像学中的研究进展进行综述。

关键词：肩关节诊断显像深度学习

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A paste based on Cu@Sn@Ag particles for die attachment under ambient atmosphere in power device packaging

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JOURNAL OF MATERIALS SCIENCE-MATERIALS IN ELECTRONICS 2020年第3期31卷 1808-1816页

作者： Liu, Jiahao Wang, Kang Yu, fuwen Hang, Chunjin Fu, Xing chen, Hongtao Li, Mingyu Harbin Inst Technol Shenzhen Dept Mat Sci & Engn Shenzhen 518055 Guangdong Peoples R China China Elect Technol Grp Corp Res Inst 54 Shijiazhuang 050081 Hebei Peoples R China Harbin Inst Technol State Key Lab Adv Welding & Joining Harbin 150001 Heilongjiang Peoples R China China Sci & Technol Reliabil Phys & Applicat Elec Guangzhou 510610 Guangdong Peoples R China

This paper presents a novel die attach material based on Cu@Sn@Ag particles, in which the outermost Ag layer prevents the oxidation of the Sn layer and expedites the consumption of the low-melting point Sn phase. The die attach material can be reflowed at 250 degrees C for 15 min under a pressure of 3 MPa in the atmosphere, subsequently, the bondline can sustain a much higher temperature up to 480 degrees C. The results show that the Sn phase was totally transformed into Cu3Sn and Ag3Sn intermetallic compounds (IMCs) after reflow. Moreover, the Cu particles were evenly distributed in the Cu3Sn and Ag3Sn IMCs. After Cu@Sn@Ag particles were heated at 250 degrees C for 6 h, the average mass increased only by 2.8%, which indicates that the oxidation resistance property of Cu@Sn@Ag particles is excellent. The average electrical resistivity of the bondline was 4.6 mu omega cm, and the thermal conductivities were 159.97 W m(-1) K-1, 142.71 W m(-1) K-1, 137.28 W m(-1) K-1 at 30 degrees C, 150 degrees C, 300 degrees C, respectively. The average shear strengths of the bondline were 25.8 MPa and 19.7 MPa at 30 degrees C and 400 degrees C, respectively. The coefficient of thermal expansion of the bondline was measured to be 15.77 x 10(-6)/degrees C. This novel paste shows great potential in die attachment in power device packaging.

关键词： Dies

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补救性支架植入在急性颅内大血管闭塞性脑梗死机械取栓再通失败后的临床应用分析

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中华神经医学杂志 2019年第2期18卷 156-161页

作者：陈付文刘金朝赵玉铁康孝理杨思福李红伟史宏生汪子文濮阳市油田总医院介入科 457000 濮阳市油田总医院急诊科 457000 濮阳市油田总医院神经内科 457000

目的探讨急性颅内大血管闭塞性脑梗死机械取栓再通失败后采用补救性支架植入治疗的有效性及安全性。方法对濮阳市油田总医院介入科自2016年1月至2018年3月行机械取栓但再通失败的29例急性颅内大血管闭塞性脑梗死患者中的18例采用补救性... 详细信息

目的探讨急性颅内大血管闭塞性脑梗死机械取栓再通失败后采用补救性支架植入治疗的有效性及安全性。方法对濮阳市油田总医院介入科自2016年1月至2018年3月行机械取栓但再通失败的29例急性颅内大血管闭塞性脑梗死患者中的18例采用补救性支架植入治疗(支架组),11例不行补救性支架植入治疗(非支架组),比较分析支架组与非支架组的最终血管再通率、并发症发生率及临床预后。结果支架组与非支架组的最终血管再通率分别为88.9%(16/18)、36.4%(4/11),预后良好率分别为55.6%(10/18)、18.2%(2/11),比较差异均有统计学意义(P<0.05);而2组在症状性颅内出血发生率[11.1%(2/18)vs.18.2%(2/11)]及死亡率[22.2%(4/18)vs.45.5%(5/11)]方面差异均无统计学意义(P>0.05)。结论急性颅内大血管闭塞性脑梗死机械取栓再通失败后采用补救性支架植入治疗可显著改善患者的临床预后且不增加颅内出血风险。

关键词：补救性支架大血管闭塞脑梗死机械取栓

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Nutrition and flavor analysis of Spirulina through co-fermentation with Lactobacillus acidophilus and Kluyveromyces marxianus and its effect on attenuating metabolic associated fatty liver disease

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JOURNAL OF FUNCTIONAL FOODS 2024年 116卷

作者： Yu, Jinhui Liu, Chao Wang, Mingjie Liu, Yuanyuan Ran, Liyuan Yu, Zichao Ma, Deyuan chen, Gao Han, fuwen You, Shengbo Bi, Yuping Wu, Yingjie Shandong Acad Agr Sci Inst Crop Germplasm Resources Jinan 250100 Peoples R China Shandong Univ Qilu Hosp Jinan 250100 Peoples R China Shandong Normal Univ Coll Life Sci Jinan 250014 Peoples R China Inner Mongolia Med Univ Affiliated Hosp Med Univ Dept Pediat Hohhot 010050 Inner Mongolia Peoples R China Shandong Univ Shandong Prov Hosp Dept Endocrinol Jinan 250021 Peoples R China Shandong Xinchuang Biotechnol Co LTD Jinan 250102 Shandong Peoples R China Shandong First Med Univ & Shandong Acad Med Sci Shandong Lab Anim Ctr Med Sci & Technol Innovat Ctr Jinan 250117 Peoples R China

Spirulina is widely known as the "Super Nutritious Food of the Future" due to its exceptional nutritional properties. In this article, we investigated the effects of fermentation using a combination of Lactobacillus acidophilus KDB-03 and Kluyveromyces marxianus GDMCC 2.119 on Spirulina. Fermentation significantly increased the total flavonoid and phenol levels in Spirulina, and enhanced the 2,2-diphenyl-1-picrylhydrazyl free radical scavenging capacity and ferric-reducing antioxidant power. Untargeted ultra-performance liquid chromatography-electrospray tandem mass spectrometry-based metabolomics and gas chromatography-ion mobility spectrometry analysis revealed alterations in the metabolites and flavor components of fermented Spirulina (FS). Furthermore, a mice experiment demonstrated that FS could effectively alleviate metabolismassociated fatty liver disease (MAFLD) by regulating liver metabolism, intestinal flora, and facilitating communication between the liver and gut. These findings suggest that fermentation could be a innovative approach to enhance the diversity of Spirulina products, and potentially be used as a strategy for the prevention and treatment of MAFLD.

关键词： Spirulina Lactobacillus acidophilus Kluyveromyces marxianus Co -fermentation MAFLD

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Browse and Concentrate: Comprehending Multimodal Content via prior-LLM Context Fusion

arXiv

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arXiv 2024年

作者： Wang, Ziyue chen, Chi Zhu, Yiqi Luo, fuwen Li, Peng Yan, Ming Zhang, Ji Huang, Fei Sun, Maosong Liu, Yang Dept. of Comp. Sci. & Tech. Institute for AI Tsinghua University Beijing China Tsinghua University Beijing China Institute of Intelligent Computing Alibaba Group China Shanghai Artificial Intelligence Laboratory Shanghai China Jiangsu Collaborative Innovation Center for Language Competence Jiangsu China

With the bloom of Large Language Models (LLMs), Multimodal Large Language Models (MLLMs) that incorporate LLMs with pretrained vision models have recently demonstrated impressive performance across diverse vision-language tasks. However, they fall short to comprehend context involving multiple images. A primary reason for this shortcoming is that the visual features for each images are encoded individually by frozen encoders before feeding into the LLM backbone, lacking awareness of other images and the multimodal instructions. We term this issue as prior-LLM modality isolation and propose a two phase paradigm, browse-and-concentrate1, to enable in-depth multimodal context fusion prior to feeding the features into LLMs. This paradigm initially "browses" through the inputs for essential insights, and then revisits the inputs to "concentrate" on crucial details, guided by these insights, to achieve a more comprehensive understanding of the multimodal inputs. Additionally, we develop training strategies specifically to enhance the understanding of multi-image inputs. Our method markedly boosts the performance on 7 multi-image scenarios, contributing to increments on average accuracy by 2.13% and 7.60% against strong MLLMs baselines with 3B and 11B LLMs, respectively. © 2024, CC BY.

关键词： Image enhancement

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Research on the Splicing Performance of G.654.E Optical Fiber

Research on the Splicing Performance of G.654.E Optical Fibe...

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2023 Asia Communications and Photonics Conference/2023 International Photonics and Optoelectronics Meetings, ACP/POEM 2023

作者： Wu, Guangzhe Xia, Xiaomeng chen, Tong Zhou, Hongyan Hu, Chao Zhang, Liyan Deng, Li Wang, Ying Li, Can Ma, Chao Li, Yang Liu, Yang Bai, fuwen Jin, Wei Wu, Jun State Grid Information & Telecommunication Branch Beijing China Yangtze Optical Fibre and Cable Joint Stock Limited Company Key Laboratory of Optical Fibre and Cable Manufacture Technology Optics Valley Laboratory Wuhan China

ISBN: (纸本)9798350312614

Novel G.654.E has been large-scale deployed in optical communication network, so it has become urgent problems to reduce the splicing loss, improve the success probability of in one splicing and unsatisfactory splicing loss from different manufacturers in practical engineering applications. Based on the theory of single-mode fiber splicing loss testing, we obtained a large number of laboratory experiment data and practical network engineering data to verify the splicing performance form the same and different manufacturers of G.654.E fiber in various aspects based on different splicing machines. And also we propose a targeted splicing optimization scheme for practical engineering applications. All of the research provides a guidance for engineering application of G.654.E optical fiber in practical network engineering. © 2023 IEEE.

关键词： G.654.E large effective area splicing ultra-low loss

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Model Composition for Multimodal Large Language Models

arXiv

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arXiv 2024年

作者： chen, Chi Du, Yiyang Fang, Zheng Wang, Ziyue Luo, fuwen Li, Peng Yan, Ming Zhang, Ji Huang, Fei Sun, Maosong Liu, Yang Dept. of Comp. Sci. & Tech. Institute for AI Tsinghua University Beijing China Tsinghua University Beijing China Institute of Intelligent Computing Alibaba Group China Shanghai Artificial Intelligence Laboratory Shanghai China Jiangsu Collaborative Innovation Center for Language Competence Jiangsu China

Recent developments in Multimodal Large Language Models (MLLMs) have shown rapid progress, moving towards the goal of creating versatile MLLMs that understand inputs from various modalities. However, existing methods typically rely on joint training with paired multimodal instruction data, which is resource-intensive and challenging to extend to new modalities. In this paper, we propose a new paradigm through the model composition of existing MLLMs to create a new model that retains the modal understanding capabilities of each original model. Our basic implementation, NaiveMC, demonstrates the effectiveness of this paradigm by reusing modality encoders and merging LLM parameters. Furthermore, we introduce DAMC to address parameter interference and mismatch issues during the merging process, thereby enhancing the model performance. To facilitate research in this area, we propose MCUB, a benchmark for assessing ability of MLLMs to understand inputs from diverse modalities. Experiments on this benchmark and four other multimodal understanding tasks show significant improvements over baselines, proving that model composition can create a versatile model capable of processing inputs from multiple modalities.1 Copyright © 2024, The Authors. All rights reserved.

关键词： Modeling languages

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Ambient noise seismic tomography of Tonglushan skarn-type Cu-Fe-Au deposit in Eastern China

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Ore Geology Reviews 2025年

作者： Jialiang Jing Guoxiong chen Pei Li fuwen Xu State Key Laboratory of Geological Processes and Mineral Resources China University of Geosciences Wuhan 430074 China Team No. 1 of the Hubei Geological Bureau Daye 435100 China

The Tonglushan (TLS) skarn-type Cu-Fe-Au deposit, located in Hubei Province of China, is facing the challenge of depletion of shallow mineral resources, highlighting the urgent need for deep mineral exploration to sustain future resource development. A range of geophysical methods has been employed to delineate subsurface lithology beneath the TLS deposit, with a particular focus on identifying skarn mineralization, which is commonly occurred along granite-marble boundaries. However, gravity and magnetic methods are less effective for detecting small geological bodies at depths > 1 km, while electromagnetic methods suffer from strong noise interferences from ongoing mining activities herein. In this study we present the first application of ambient noise tomography (ANT) to TLS ore deposit for imaging shear wave velocity structures by using a dense linear seismic array (∼10 km). The velocity images agree well with geological information revealed by drilling holes, accurately delineating the marble formation and fault structures, both of which are characterized by low-velocity anomalies. Notably, the magnetic responses of lithological model inferred from ANT agree well with the observed aeromagnetic data. The inversion results precisely delineate the interfaces between granite and marble, where the largest ore body of the TLS ore deposit is located. The geological model derived from geophysical inversion results provides a more comprehensive understanding of the TLS Cu-Fe-Au mineral system. It reveals that the granite intrusion extends to a depth of ca. 2.5 km, while the captive marble formation may reach depths of up to 2 km beneath the TLS ore deposit. These results provide key clues for finding potential skar-type Cu-Fe-Au ore bodies related to granite-sediment boundaries in the deep space (at ca. 1.0–2.0 km) of TLS ore deposits.

关键词： Ambient noise tomography Passive seismic exploration Shear wave velocity Tonglushan ore deposit Skar-type ore deposit

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Optical thermometry of Tm³⁺/Yb³⁺ Co-doped Ba3Gd2F12 up-conversion glass-ceramic with high sensitivity

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JOURNAL OF SOLID STATE CHEMISTRY 2022年 308卷 122927-122927页

作者： Zhang, Qihao Li, Liang Liu, fuwen Li, Sixing Wei, Xiantao Wang, Wenming chen, Hongmei Pan, Yan Li, Yong Anhui Univ Technol Sch Math & Phys Maanshan 243000 Peoples R China Univ Sci & Technol China Phys Expt Teaching Ctr Sch Phys Sci Hefei 230026 Peoples R China Anhui Univ Technol Anal & Testing Cent Facil Maanshan 243000 Peoples R China

In this work, Tm3+/Yb3+ co-doped Ba3Gd2F12 oxyfluoride glass-ceramic was synthesized by the conventional melt-quenching method, and an optical thermometer with high sensitivity was proposed accordingly. The structural and optical properties of Ba3Gd2F12: Tm3+/Yb3+ glass-ceramics were systematically investigated. After crystallization, the enrichment of Tm3+ ions in the Ba3Gd2F12 lattice leads to enhancing emission intensity, the prolonged lifetime of Tm3+ ions, and Stark splitting of emission spectra. The dependence of optical properties of Ba3Gd2F12: Tm3+ glass-ceramics on temperature were explored based on fluorescence intensity ratio of F-3(2,3) -> H-3(6) and (1)G(4)-> F-3(4) transitions of Tm3+ ions. The maximum value of relative sensitivity SR reaches 1.02% K 1 at 457 K. This work indicates that the oxyfluoride glass-ceramic embedded with Ba3Gd2F12: Tm3+/Yb3+ nano particles is a candidate material with good performance for optical temperature sensors.

关键词： Optical thermometry Ba3Gd2F12 Yb3+/Tm3+ Optical materials Glass ceramics Up-conversion

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