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Boosting propane dehydrogenation of defective S-1 stabilized singleatom Pt and ZnO catalysts via coordination environment regulation

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Nano Research 2024年第7期17卷 5884-5896页

作者： fuwen Yang Jie Zhang Jinwei chen Gang Wang Tong Yu Qian Li Zongbo Shi Qiushi Sun Runsheng Zhuo Ruilin Wang College of Materials Science and Engineering Sichuan UniversityChengdu 610065China Engineering Research Center of Alternative Energy Materials&Devices Ministry of EducationSichuan UniversityChengdu 610065China REZEL Catalysts Corporation Shanghai 200120China

Pt single atoms catalysts with precise coordination environment and high stability are expected to achieve high performance of propane dehydrogenation(PDH).In this work,an innovative synthetic strategy is proposed to construct the S-1@0.1Pt9Zn@DPS-1 nanocomposite as a highly efficient PDH *** engineering is applied to induce the formation of defective porous silicalite-1(DPS-1),which is favorable for achieving the uniformly distributed ZnO *** ZnO nanoclusters were further served as anchoring sites to stabilize the isolated Pt *** structural characterization revealed that penta-O coordinated Pt single atom coupled with ZnO nanoclusters decorated on the ***,the atomically dispersed Pt atoms with the ideal coordination environment could act as the predominant active sites for PDH *** expected,the optimal S-1@0.1Pt9Zn@DPS-1 catalyst delivered an excellent PDH performance(propane conversion of 40.7%,propylene selectivity of 97.5%)and good cycling regeneration *** work provides a new way for improving the activity and stability of catalysts in the field of industrial catalysts.

关键词： defect engineering single platinum atom coordination environment propane dehydrogenation propylene

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Low-temperature growth and characterization of β-Ga2O3 thin films by ECR-PEMOCVD

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MATERIALS SCIENCE IN SEMICONDUCTOR PROCESSING 2025年 194卷

作者： Zhao, Shuang chen, Jie Ma, Chunyu Li, Jian Wang, Xuan Zhao, Yaxin Liu, Hongsheng Dzmitry, Karpinski Qin, fuwen Dalian Univ Technol Sch Phys Key Lab Mat Modificat Laser Ion & Electron Beams Dalian 116024 Peoples R China NAS Belarus Sci Pract Mat Res Ctr Minsk 220072 BELARUS

In this paper, (3-Ga2O3 thin films were grown on c-plane sapphire (0001) substrates using an electron cyclotron resonance plasma enhanced metal organic chemical vapor deposition (ECR-PEMOCVD), with TMGa and O2 as precursors for Ga and O, respectively. The structure, optical, morphological, chemical components and photoluminescence properties of as-grown (3-Ga2O3 thin film were characterized by XRD, UV-Vis-DRS, AFM, SEM, XPS, and PL techniques. In addition, the grown sample was fabricated to detect 254 nm ultraviolet light at room temperature, with the photo-dark current ratio as high as 2.5 x 103 and fast response/decay time (0.2/0.12 s) under 915 mu W/cm2. DFT calculations further exhibit the basic properties of (3-Ga2O3, including lattice parameters, electronic structure and absorption spectrum. These results suggest that the used ECR-PEMCVD can achieve low-temperature growth of (3-Ga2O3 thin films, and display good potential for practical applications of ultraviolet light response.

关键词： ECR-PEMOCVD Low-temperature growth

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Proposal of Industry 5.0-Enabled Sustainability of Product-Service Systems and Its Quantitative Multi-Criteria Decision-Making Method

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PROCESSES 2024年第3期12卷 473页

作者： Jin, Qichun chen, Huimin Hu, fuwen Wuxi City Vocat & Tech Coll Sch Ind Internet Wuxi 214153 Peoples R China North China Univ Technol Sch Mech & Mat Engn Beijing 100144 Peoples R China

In the wake of Industry 4.0, the ubiquitous internet of things provides big data to potentially quantify the environmental footprint of green products. Further, as the concept of Industry 5.0 emphasizes, the increasing mass customization production makes the product configurations full of individuation and diversification. Driven by these fundamental changes, the design for sustainability of a high-mix low-volume product-service system faces the increasingly deep coupling of technology-driven product solutions and value-driven human-centric goals. The multi-criteria decision making of sustainability issues is prone to fall into the complex, contradictory, fragmented, and opaque flood of information. To this end, this work presents a data-driven quantitative method for the sustainability assessment of product-service systems by integrating analytic hierarchy process (AHP) and data envelopment analysis (DEA) methods to measure the sustainability of customized products and promote the Industry 5.0-enabled sustainable product-service system practice. This method translates the sustainability assessment into a multi-criteria decision-making problem, to find the solution that meets the most important criteria while minimizing trade-offs between conflicting criteria, such as individual preferences or needs and the life cycle sustainability of bespoke products. In the future, the presented method can extend to cover more concerns of Industry 5.0, such as digital-twin-driven recyclability and disassembly of customized products, and the overall sustainability and resilience of the supply chain.

关键词： Industry 4.0 Industry 5.0 sustainability product-service system design for sustainability multi-criteria decision making analytic hierarchy process data envelopment analysis

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Damping Control for Drivetrain Torsional Vibration Attenuation of Grid Forming Wind Turbines with DFIG 4

Damping Control for Drivetrain Torsional Vibration Attenuati...

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4th Power System and Green Energy Conference (PSGEC)

作者： Guo, Ziteng Zhang, Yu Zhang, chen Zong, Haoxiang Wang, fuwen Cai, Xu Shanghai Jiao Tong Univ Key Lab Control Power Transmiss & Convers Minist Educ Shanghai Peoples R China Shanghai Zhonglv New Energy Technol CO LTD Shanghai Peoples R China

ISBN: (纸本)9798350365573;9798350365580

Research on grid-forming (GFM) control strategies for wind turbines (WTs) has primarily focused on the electromagnetic characteristics of the WTs, overlooking the impact on the drivetrain. This limitation has hindered the application of GFM control strategies in engineering. To fill this gap, a two-mass drivetrain model is built to assess the influence of the bandwidth of the virtual synchronous generator (VSG) control strategy on drivetrain torsional vibration characteristics. A comparison of torsional vibration characteristics between the GFM-WT and traditional grid-following WT (GFL-WT) highlights the need for increased attention to drivetrain torsional vibration in GFM-WT. Then, the inadequacy of the traditional drivetrain torsional vibration suppression strategy (T-DTVSS) when applied in VSG control is examined. Finally, a novel drivetrain torsional vibration suppression strategy named virtual synchronous phase angle compensation drivetrain torsional vibration suppression strategy (VSPAC-DTVSS) is proposed, and the efficacy of this strategy is validated through simulation using PSCAD.

关键词： GFM-WT drivetrain torsional vibration suppression strategy

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The impact of perioperative opioid use on postoperative outcomes following spinal surgery: a meta-analysis of 60 cohort studies with 13 million participants

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SPINE JOURNAL 2024年第2期24卷 278-296页

作者： Luo, Mingjiang Shi, fuwen Wang, Hongxu chen, Zuoxuan Dai, Huijie Shi, Yuxin chen, Jiang Tang, Siliang Huang, Jingshan Xiao, Zhihong Univ South China Affiliated Hosp 2 Hengyang Med Sch Dept Spinal Surg Hengyang Hunan Peoples R China Univ South China Hengyang Med Sch Hengyang Hunan Peoples R China Xinjiang Med Univ Affiliated Hosp 1 Affiliated Stomatol Hosp Dept Pediat Dent Urumqi 830054 Peoples R China Univ South China Affiliated Hosp 2 Hengyang Med Sch Dept Spine Surg Hengyang 421000 Peoples R China

BACKGROUND CONTEXT: An important factor for the prognosis of spinal surgery is the perioperative use of opioids. However, the relationship is not clear. PURPOSE: The purpose of this study was to evaluate the effect of perioperative opioid use on the prognosis of patients following spinal surgery. STUDY DESIGN/SETTING: Systematic review and meta -analysis. OUTCOME MEASURES: A meta -analysis was conducted using the random -effects method to calculate pooled odds ratios (ORs) with 95% confidence intervals (CIs). METHODS: The PubMed, Embase, and Cochrane Library databases were systematically searched to find relevant articles that were published until September 2, 2022. The primary outcome was prolonged postoperative opioid use, and secondary outcomes included the length of stay (LOS), reoperation, the time to return to work (RTW), postoperative complications, gastrointestinal complications, new permanent disability, central nervous system events and infection. In addition, subgroup analysis of the primary outcome was conducted to explore the main sources of heterogeneity, and sensitivity analysis of all outcomes was performed to evaluate the stability of the results. RESULTS: A total of 60 cohort studies involving 13,219,228 individuals met the inclusion criteria. Meta -analysis showed that perioperative opioid use was specifically related to prolonged postoperative opioid use (OR 6.91, 95% CI 6.09 to 7.84, p<.01). Furthermore, the results also showed that perioperative opioid use was significantly associated with prolonged LOS (OR 1.74, 95% CI 1.39 to 2.18, p<.01), postoperative complications (OR 1.72, 95% CI 1.26 to 2.36, p<.01), reoperation (OR 2.38, 95% CI 1.85 to 3.07, p<.01), the time to RTW (OR 0.45, 95% CI 0.39 to 0.52, p<.01), gastrointestinal complications (OR 1.39, 95% CI 1.30 to 1.48, p<.01), central nervous system events (OR 1.99, 95% CI 1.21 to 3.27, p=.07) and infection (OR 1.22, 95% CI 1.09 to 1.36, p=.01). These results were corroborated by the trim -a

关键词： Cohort study Meta-analysis Opioid use Spinal surgery

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Exploring technical improvements for environmental nucleic acids-based biodiversity assessment and management in coastal ecosystems

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JOURNAL OF ENVIRONMENTAL MANAGEMENT 2025年 377卷 124724页

作者： Wang, fuwen Xiong, Wei Liu, Yue Zhai, Xiaohui Zhou, Juan Li, Haitao Huang, Xuena chen, Yiyong Zhou, Kai Zhan, Aibin Chinese Acad Sci Res Ctr Ecoenvironm Sci 18 Shuangqing Rd Beijing 100085 Peoples R China Chinese Acad Sci Univ Chinese Acad Sci 19A Yuquan Rd Beijing 100049 Peoples R China Shenzhen Res & Promot Ctr Marine Dev 69 Xinwen Rd Shenzhen 518034 Peoples R China Minist Nat Resources Peoples Republ China South China Sea Ecol Ctr 155 Xingang Road West Guangzhou Peoples R China Nansha lslands Coral Reef Ecosyst Natl Observat & 155 Xingang Rd West Guangzhou 510275 Peoples R China Minist Nat Resources Peoples Republ China MNR Key Lab Marine Environm Survey Technol & Applicat 155 Xingang Rd West Guangzhou 510275 Peoples R China

Assessing and conserving marine biodiversity remain critical global challenges, particularly in highly disturbed coastal regions. The use of environmental DNA (eDNA)-metabarcoding has revolutionized biodiversity assessment and management;however, the prevalence of both false positives and negatives continues to be a significant concern. To address these technical errors, we tested two potential methodological improvements in the highly disturbed Guangdong-Hong Kong-Macao Greater Bay Area: (1) the use of random whole-genome amplification (WGA) to reduce false negatives derived from low eDNA concentration, and (2) the application of environmental RNA (eRNA)-metabarcoding to mitigate false positives arising from eDNA contamination by human activities. Using fish communities as our target, we found that WGA enhanced downstream PCR amplification for metabarcoding but significantly reduced the detection of rare taxa, altered community structure, and increased false negatives (p < 0.001 for all tests). Interestingly, WGA led to higher levels of false negatives in more biodiverse communities. eDNA-metabarcoding revealed that 20.9%-23.6% of detected taxa were pure freshwater species (false positives) incapable of surviving in estuarine and coastal regions, highlighting the often-overlooked eDNA contamination in disturbed coastal ecosystems. In contrast, eRNA-metabarcoding significantly reduced false positives (p < 0.001), with error taxa accounting for only 2.5%-6.3% of all detections. Comparisons between eDNA and eRNA metabarcoding further revealed differences in their rare taxa recovery capacity. The findings provide critical insights into method selection for biodiversity assessment and management in highly disturbed coastal regions and highlight the need for further technical improvement of eDNA and eRNA-based biodiversity monitoring and conservation in aquatic ecosystems.

关键词： Coastal area eDNA eRNA False negative False positive Whole genome amplification

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Second generation androgen receptor antagonists and challenges in prostate cancer treatment

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CELL DEATH & DISEASE 2022年第7期13卷 1-11页

作者： chen, Yanhua Zhou, Qianqian Hankey, William Fang, Xiaosheng Yuan, fuwen Shanghai Univ Tradit Chinese Med Acad Integrat Med Shanghai 201203 Peoples R China Univ N Carolina Dept Genet Chapel Hill NC 27599 USA Shandong First Med Univ Dept Hematol Shandong Prov Hosp Jinan 271000 Shandong Peoples R China

Prostate cancer is a hormone-dependent malignancy, whose onset and progression are closely related to the activity of the androgen receptor (AR) signaling pathway. Due to this critical role of AR signaling in driving prostate cancer, therapy targeting the AR pathway has been the mainstay strategy for metastatic prostate cancer treatment. The utility of these agents has expanded with the emergence of second-generation AR antagonists, which began with the approval of enzalutamide in 2012 by the United States Food and Drug Administration (FDA). Together with apalutamide and darolutamide, which were approved in 2018 and 2019, respectively, these agents have improved the survival of patients with prostate cancer, with applications for both androgen-dependent and castration-resistant disease. While patients receiving these drugs receive a benefit in the form of prolonged survival, they are not cured and ultimately progress to lethal neuroendocrine prostate cancer (NEPC). Here we summarize the current state of AR antagonist development and highlight the emerging challenges of their clinical application and the potential resistance mechanisms, which might be addressed by combination therapies or the development of novel AR-targeted therapies.

关键词： Cancer Drug discovery

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Comparative transcriptomics analysis of testicular miRNA from indicine and taurine cattle

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ANIMAL BIOTECHNOLOGY 2023年第4期34卷 1436-1446页

作者： Dong, Zheng Ning, Qingqing Liu, Yangkai Wang, Shikang Wang, fuwen Luo, Xiaoyu chen, Ningbo Lei, Chuzhao Northwest A&F Univ Coll Anim Sci & Technol Yangling 712100 Shaanxi Peoples R China

Numerous studies have shown that several microRNAs (miRNAs) are specifically expressed in testis, play an essential role in regulating testicular spermatogenesis. Hainan and Mongolian cattle are two representative Chinese native cattle breeds representing Bos indicus (indicine cattle) and Bos taurus (taurine cattle), respectively, which are distributed in hot Hainan and cold Inner Mongolia province. To study the functional differences of miRNA in spermatogenesis between indicine and taurine cattle, six mature testes samples from indicine cattle (n = 3) and taurine cattle (n = 3) were collected, respectively. We detected miRNA expression using small RNA sequencing technology following bioinformatic analysis. A total of 578 known miRNAs and 132 novel miRNAs were detected in the six libraries. Among the 710 miRNAs, 564 miRNAs were expressed in both indicine and taurine cattle, 73 miRNAs were found solely in indicine cattle and 73 miRNAs were found solely in taurine cattle. After further analysis, among the miRNAs were identified in both indicine and taurine cattle, 184 miRNAs were differentially expressed (|log2 fold change| >= 1 and corrected p-value <0.05). Among the miRNAs that were only expressed in indicine cattle, 10 miRNAs were differentially expressed, whereas, among the miRNAs that were only expressed in taurine cattle, six miRNAs were differentially expressed. The enrichment analysis result showed that predicted target genes of a total of 200 differentially expressed miRNAs were enriched on some testicular spermatogenesis-related Kyoto Encyclopedia of Genes and Genomes (KEGG) pathways, especially mitogen-activated protein kinase (MAPK) signaling pathway. These findings identify miRNAs as key factors to regulate spermatogenesis in both indicine and taurine cattle, which may also be helpful for improving cattle reproductive performance in future studies.

关键词： Cattle miRNA expression profiles spermatogenesis

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采用“双侧垂直错位穿刺法”与“双侧水平裂隙穿刺法”行经皮椎体成形术在治疗Ⅰ期Kümmell病的疗效对比

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生物骨科材料与临床研究 2022年第6期19卷 30-37页

作者：郝国兵朱泽兴刘昆杨勇张楠闫双宝陈福文乔林中国人民解放军火箭军特色医学中心骨科北京100088

目的探究采用“双侧垂直错位穿刺法”与“双侧水平裂隙穿刺法”行经皮椎体成形术(PVP)在治疗I期Kümmell病中的疗效对比。方法回顾性分析2014年1月至2021年1月在中国人民解放军火箭军特色医学中心接受PVP治疗的I期Kümmell病患... 详细信息

目的探究采用“双侧垂直错位穿刺法”与“双侧水平裂隙穿刺法”行经皮椎体成形术(PVP)在治疗I期Kümmell病中的疗效对比。方法回顾性分析2014年1月至2021年1月在中国人民解放军火箭军特色医学中心接受PVP治疗的I期Kümmell病患者53例,其中采取“双侧垂直错位穿刺法”治疗25例(A组),采取“双侧水平裂隙穿刺法”治疗28例(B组)。比较两组的手术时间、骨水泥注入量、骨水泥渗漏率、骨水泥分布及并发症情况,并记录术前与术后1 d、1个月、3个月、6个月视觉评分量表(VAS)和Oswestry功能障碍指数(ODI),通过X线或CT检查测量并记录术前、术后伤椎前缘与中线高度和Cobb角,并观察骨水泥松动或移位及伤椎再骨折发生情况,末次随访采用改良MacNab标准评估手术的优良率。结果两组患者均顺利完成手术,均获定期随访。A组较B组手术时间相当(P>0.05),骨水泥注入量更多(P<0.05);A组术中2例出现骨水泥渗漏,渗入椎间盘1例、椎体前侧1例,无临床症状;B组术中9例出现骨水泥渗漏,渗入椎间盘6例、椎体前侧3例,无临床症状;A组术中骨水泥渗漏率较低(P<0.05),术后椎体裂隙及骨折线周围骨水泥分布更广泛(P<0.05);两组术中均无脊髓、椎前大血管损伤,无肺栓塞等并发症发生。与术前比较,两组患者术后1 d、1个月、3个月、6个月VAS、ODI显著降低(P<0.05);A组与B组比较,术前、术后VAS、ODI在两组间差异无统计学意义(P>0.05);与术前比较,两组患者术后1 d、1个月、3个月、6个月伤椎前缘与中线高度显著增加(P<0.05),Cobb角测量值显著降低(P<0.05);A组与B组比较,术后1 d、1个月、3个月、6个月伤椎前缘与中线高度变化、伤椎Cobb角变化差异无统计学意义(P>0.05);末次随访时两组患者均无骨水泥松动或移位及伤椎再骨折情况发生,采用改良MacNab标准评定临床疗效:A组优23例、良2例,B组优19例、良9例,A组优秀率高于B组(P<0.05)。结论治疗Ⅰ型Kümmell病时,与“双侧水平裂隙穿刺法”经皮椎体成形术相比,“双侧垂直错位穿刺法”经皮椎体成形术术中的骨水泥渗漏率更低,骨水泥分布更广泛,术后早期治疗效果相当,中期效果更确切。

关键词：经皮椎体成形术 Kümmell病骨水泥双侧垂直错位穿刺法

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IP防护等级的测试与装置

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现代信息科技 2019年第14期3卷 125-127页

作者：陈福文广州京信通信系统工程有限公司

在我们生活中,与水有接触或者可能接触的电器产品,在国家标准中都对其有相应的防护要求。一般IP防护等级实际的生产过程中经常要用水来测试,然而由于我司射频无源器件产品本身有电镀要求,产品一旦进水可能会对器件造成不可修复的伤害,... 详细信息

在我们生活中,与水有接触或者可能接触的电器产品,在国家标准中都对其有相应的防护要求。一般IP防护等级实际的生产过程中经常要用水来测试,然而由于我司射频无源器件产品本身有电镀要求,产品一旦进水可能会对器件造成不可修复的伤害,而且测试结果不直观,作业效率很低,为此我们通过实验换算对应IP等级的气密性测试参数关系,改变测试方法,引入差压式气密性测试仪进行产品防护等级检验。并结合本公司的产品特点和品质要求设计一种气动原理的自动测试装置,用于改善测试环节依靠人工、效率低下、异常品无法追溯历史记录以及出厂品质得不到保证等问题。

关键词： IP防护等级测试参数测试方法联动测试数据保存

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