Purpose: Based on optical coherence tomography angiography (OCTA), we investigate the effects of posterior scleral reinforcement surgery on the fundus structure and function in patients with high myopia. Methods: Retr...
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Purpose: Based on optical coherence tomography angiography (OCTA), we investigate the effects of posterior scleral reinforcement surgery on the fundus structure and function in patients with high myopia. Methods: Retrospective clinical study. Forty cases (41eyes) of high myopia patients who underwent posterior scleral reinforcement surgery at Chengdu University of Traditional Chinese Medicine Affiliated Silver Eye Hospital from January 2022 to January 2025 were selected. Follow-up periods included postoperative 3 months, 6 months, and 1 year. Key indicators before and after surgery were compared, including best-corrected visual acuity (BCVA), axial length (AL), spherical equivalent (SE), retinal thickness (RT), choroidal thickness (CT), and Superficial retinal capillary plexus density (SCP), deep retinal capillary plexus density (DCP), choroidal vascularity index (CVI), choroidal stromal vascularity index (CSI). Results: The study included 40 patients (41 eyes), comprising 9 male patients (9 eyes) and 31 female patients (32 eyes), with a mean age of 42.05 +/- 18.71 *** the last follow-up, patients showed significantly shortened AL (P < 0.001), significantly improved BCVA (P < 0.05), and significantly increased CT (P < 0.05).SCP also exhibited significant postoperative increases (P < 0.05). Additionally,CVI and CSI showed significant postoperative elevation (P < 0.05). Conclusion: This study demonstrates that posterior scleral reinforcement achieves axial stabilization through mechanical reinforcement, mitigates vitreous traction forces on the retina and choroid, enhances visual acuity, improves choroidoretinal microcirculation, and optimizes fundus architecture.
This work provides a contrastive analysis of Sb distribution in Sn-57Bi-1Sb solder by WDS mapping, EDS count map and EDS net map. The mapping analysis on the same region shows that the WDS mapping provides the more ac...
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This work provides a contrastive analysis of Sb distribution in Sn-57Bi-1Sb solder by WDS mapping, EDS count map and EDS net map. The mapping analysis on the same region shows that the WDS mapping provides the more accurate data on the distribution of Sb compared with EDS analysis, including the concentration gradient of dissolved Sb and the fine SnSb particles with size less than 1 mu m. WDS equipped with the enhanced spectral resolution is a critical technique to separate the complex overlap spectrum, which was recommended for the Sb detection in Sb-doped solders.
This paper proposes an innovative externally-hung self-centering rocking wall (ESRW) structural system for retrofitting existing reinforced concrete structures. Reinforced corbels are installed on the columns of an ex...
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This paper proposes an innovative externally-hung self-centering rocking wall (ESRW) structural system for retrofitting existing reinforced concrete structures. Reinforced corbels are installed on the columns of an existing structure to which rocking walls having unbonded post-tensioned tendons are connected using H-shaped connectors. The seismic performance and self-centering ability of the ESRW were investigated through a series of shaking table tests. For comparison, an unretrofit control structure (UCS) was also tested. The UCS was severely damaged under peak ground acceleration (PGA) = 1.2 g test conditions: some reinforcing bars were fractured and the UCS was close to collapse. For the ESRW, the damage was significantly reduced: there were only minor cracks appearing at PGA = 1.5 g test conditions and no damage appeared at the corners of the rocking walls. The maximum story drift and residual deformation of the ESRW were reduced 88% and 92%, respectively, relative to the UCS test. The ESRW structure showed desirable seismic performance and self-centering characteristics during shaking table tests.
This paper summarizes the experimental results of longitudinal embedding tests of bolted engineered bamboo connections. Six groups of bolted engineered bamboo connection specimens were prepared and tested monotonicall...
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This paper summarizes the experimental results of longitudinal embedding tests of bolted engineered bamboo connections. Six groups of bolted engineered bamboo connection specimens were prepared and tested monotonically up to failure. Test variables were bolt diameter and type of engineered bamboo: laminated bamboo or bamboo scrimber. Connection stiffness and embedding strength of the specimens of bamboo scrimber were greater than those of the specimens of the laminated bamboo - reflecting the difference in material density. Embedding strength of the laminated bamboo was insensitive to bolt diameter whereas embedding strength of the bamboo scrimber decreased with an increase of the bolt diameter. It was shown that in order to accurately model bolt embedding into bamboo, a foundation model is required. Reduction factors for strength and modulus for such a model were calibrated using experimental results. A parametric study addressing friction and foundation model size is presented.
This paper summarizes the results of numerical simulation and fragility analysis of a five-story column-and-beam glulam frame with chevron steel-timber buckling restrained braces (BRBs). Key parameters of the rotation...
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This paper summarizes the results of numerical simulation and fragility analysis of a five-story column-and-beam glulam frame with chevron steel-timber buckling restrained braces (BRBs). Key parameters of the rotational behavior of the bolted beam-to-column connections and column base connections were modeled and calibrated using shaking table test results. Prediction methods of the stiffness and capacity of the steel-timber BRBs were proposed and validated with the test results. An FEM model of the glulam frame with steel-timber BRBs was developed to capture the frame seismic response and validated using shaking table test results. The FEM model which considered damping change and damage accumulation achieved good agreement with shaking table test results, with the modelling errors of displacement amplitude for most condi-tions less than 15 %. Fragility analysis of the frame was conducted based on the validated FEM model. The probability of exceeding the collapse prevention limit state under the VII-rare earthquake excitations was reduced to close to zero when steel-timber BRBs were used. This study demonstrates the potential for using glulam frames with steel-timber BRBs in Chinese VII seismic regions.
ScopeAge-related increases in retinal iron are involved in the development of retinal degeneration. The recently discovered iron-dependent mechanism of cell death known as ferroptosis has been linked to a wide range o...
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ScopeAge-related increases in retinal iron are involved in the development of retinal degeneration. The recently discovered iron-dependent mechanism of cell death known as ferroptosis has been linked to a wide range of pathologies. However, its role in iron overload-induced retinal degeneration is still uncertain. Puerarin has been associated with retinal protection. The purpose of this research is to determine how puerarin prevents retinal ferroptosis under iron overload *** and resultsModels of iron overload in Kunming mice, 661W cell, and ARPE-19 cell are established. Increased iron deposition significantly worsens retinal pathology, decreases cell viability, and induces ferroptotic changes. Puerarin mitigates iron overload-induced ferroptosis by decreasing excessive iron through the regulation of iron handling proteins and lowering lipid peroxidation through the inhibition of cyclooxygenase 2 expression and activation of the nuclear factor-E2-related factor 2 (Nrf2) signaling pathway and downstream ferroptosis-related proteins (solute carrier family 7 member 11, glutathione peroxidase 4 and heme oxygenase-1). The protective effect of puerarin on ferroptosis is diminished by the Nrf2-specific inhibitor *** findings suggest targeting ferroptosis may be a novel strategy for the management of retinal degeneration. Puerarin may exert some of its ocular benefits by attenuating ferroptosis. Puerarin ameliorates retinal pathology, increases retinal cell viability, and protects against ferroptotic changes such as increased iron deposits and enhanced lipid peroxidation. Potential antiferroptotic methods include decreasing excessive iron by regulating iron handling proteins and lowering lipid peroxidation by inhibiting COX2 expression and activating the Nrf2 signaling pathway as well as other downstream ferroptosis-related proteins (GPX4, SLC7A11, and HO-1).image
Harvesting waste heat into electricity through thermoelectric (TE) material can make a great contribution to reducing energy consumption and environment pollution. Cu2S has proved itself to be a highly promising TE ma...
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Harvesting waste heat into electricity through thermoelectric (TE) material can make a great contribution to reducing energy consumption and environment pollution. Cu2S has proved itself to be a highly promising TE material, whereas the poor electrical property restricts its practical application. Therefore, the way to improve its electrical property by doping elements with high carrier concentration in an environmental-friendly method accelerate its application. Herein, Ag nanoparticles are incorporated into a p-type Cu2S (Ag/Cu2S) by a facile hydrothermal method to improve the thermoelectric properties. The introduction of Ag can effectively tune the carrier concentration, resulting in a high power factor of 1698 mu W m(-1) K-2;meanwhile, Ag doping can also enhance the phonon scattering, further reducing the thermal conductivity. Eventually, a ZT(max) peak value & AP;1.4 @ 773 K is achieved in the 0.5 wt% Ag-doped Cu2S samples. The design principle for Ag/Cu2S composites opens up a new pathway for the synthesis and application of thermoelectric material.(c) 2022 Elsevier B.V. All rights reserved.
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