检索结果-内蒙古大学图书馆

Clusteroluminescence from Random Aggregation of Micrometers to Ordered Assembly of Sub-10 Nanometers by Space-Confined Template Synthesis

引用

SMALL 2025年 e2412133页

作者： Wu, Riliga dai, hongyu Guan, Weijiang Lu, Chao Beijing Univ Chem Technol State Key Lab Chem Resource Engn Beijing 100029 Peoples R China Zhengzhou Univ Coll Chem Pingyuan Lab Zhengzhou 450001 Peoples R China

Clusteroluminescence (CL) clusters in the absence of aromatic or pi-conjugated structures have emerged as a new family of luminescent materials due to their abundant sources and inherent biocompatibility. However, there is an inborn challenge in controlling the size of CL clusters from random aggregation of micrometers to ordered assembly of sub-10 nanometers. Such an inherent drawback significantly restricts their progress from theoretical research to practical applications. To address this obstacle, a novel approach using space-confined templates is proposed to synthesize CL clusters with tunable sizes. Space-confined templates with sizes of approximate to 2-6 nm are constructed to effectively confine non-aromatic molecules, yielding size-controllable and luminescence-tunable CL clusters. The versatility of this synthetic strategy is further proved by using non-conjugated molecules, such as L-valine and L-isoleucine. Finally, the potential applications of the synthesized CL clusters have been implemented in cell nucleus imaging owing to their sub-10 nm size and efficient luminescence. The success of this work not only offers a versatile space-confined approach to synthesize size-tunable CL clusters within sub-10 nm, but also opens new avenues for the deployment of CL clusters in advanced applications.

关键词： clusteroluminescence confined templates micelle nanoscale

来源：评论

学校读者我要写书评

暂无评论

Disinhibition of hippocampal parvalbumin interneurons on pyramidal neurons participates in LPS-induced cognitive dysfunction

引用

NEUROSCIENCE LETTERS 2024年 821卷 137614页

作者： Tan, Xiaoxiang Ma, hongyu Guo, Xinqi Mao, Meng Qiu, Lili dai, hongyu dai, Yuchen Cao, Jinyuan Ma, Huijie Sun, Jie Southeast Univ Zhongda Hosp Sch Med Dept Anesthesiol Nanjing Jiangsu Peoples R China Hebei Med Univ Dept Physiol Shijiazhuang Hebei Peoples R China Nanjing Med Univ Affiliated Stomatol Hosp Dept Anesthesiol Nanjing Jiangsu Peoples R China

Background: The vulnerability of hippocampal pyramidal (PY) neurons played a key role in the onset of cognitive impairment. Multiple researches revealed that neuroinflammation together with microglia activation and parvalbumin (PV) interneurons participated in the pathogenesis of cognitive dysfunction. However, the underlying mechanism was still unclear. This study aimed to determine whether microglia activation would induce PV interneurons impairment and PY neurons disinhibition, and as a result, promote cognitive dysfunction after lipopolysaccharide (LPS) challenge. Methods: Male C57BL/6J mice were injected with LPS to establish systemic inflammation model, and animal behavioral tests were performed. For chemogenetics, the virus was injected bilaterally into the CA1 region. Clozapine N-Oxide (CNO) was used to activate the PV interneurons. Whole-cell patch clamp recording was applied to detect spontaneous inhibitory post synaptic current (sIPSC) and spontaneous excitatory post synaptic current (sEPSC) of PY neurons in the CA1 region. Results: LPS induced hippocampal dependent memory impairment, which was accompanied with microglia activation. Meanwhile, PV protein level in hippocampus were decreased, and IPSCs of PY neurons in the CA1 were also suppressed. Minocycline reversed all the above changes. In addition, rescuing PV function with CNO improved memory impairment, sIPSCs of PY neurons and perisomatic PV boutons around PY neurons without affecting microglia activation. Conclusion: Disinhibition of hippocampal parvalbumin interneurons on pyramidal neurons participates in LPS-induced cognitive dysfunction.

关键词： Cognitive dysfunction Parvalbumin interneurons Pyramidal neurona Microglia LPS

来源：评论

学校读者我要写书评

暂无评论

Tuned amphiphilic assembly in water for 100 % [2+2] photocycloaddition and highly efficient isomeric separation

引用

NANO TODAY 2025年 61卷

作者： Zhao, Yanyu Zhang, Xiaodie dai, hongyu Wang, Tao Guan, Weijiang Wei, Peifa Anhui Univ Inst Phys Sci & Informat Technol Key Lab Struct & Funct Regulat Hybrid Mat Minist EducAnhui Graphene Engn Lab Hefei 230601 Peoples R China Beijing Univ Chem Technol State Key Lab Chem Resource Engn Beijing 100029 Peoples R China

Photoresponsive smart materials suffer from elusive reaction pathways and complicated purification processes, which contradicts the principles of green chemistry and atomic economy chemistry. Herein, based on simply tuned self- and co-assembly of an amphiphile in water, a "one stone, two birds" function is achieved in a controllable photoresponsive system, that is quantitative photocycloaddition and efficient E/Z isomeric separation. Self-assembly driven by hydrophobicity refines the photochemical process to a single pathway with remarkable 100 % conversion. The synergy of thermal responsiveness and ion-induced co-assembly enables selective crystallization, facilitating highly efficient E/Z isomeric separation. This study demonstrates the hostguest interactions between open linear oligoethylene glycol chains and cations by single crystal. The tunable transparency and the inherent aggregated emission allow for visible tracking of both the photocycloaddition and separation processes, providing valuable insights into the underlying mechanisms. This work offers a new paradigm for the development of green and controllable photoresponsive systems.

关键词： Photoresponsive materials Self-assembly Amphiphilie Photocycloaddition E / Z isomers

来源：评论

学校读者我要写书评

暂无评论

Environmental Protection and Energy Color Changing Clothing Design under the Background of Sustainable Development

引用

Journal of Renewable Materials 2022年第11期10卷 2717-2728页

作者： Jingyu dai hongyu dai Yutong Xie T.Indumathi College of Art Design and Media Sanda UniversityShanghai201209China Data science institute Vanderbilt UniversityNashville37212USA Center of Art Education Shanghai University of Medicine&Health SciencesShanghai201318China PSG College of Technology Coimbatore641004India

In order to promote the application of clean energy technology in clothing and promote the integration of industrial development and artificial intelligence wearable technology,this study elaborates the energy application characteristics of intelligent wearable products at home and abroad and its application in different fields,aiming at the current research status of wearable technology in the field of textile and *** wearable distributed generation technology is classified,and a creative clothing design for detecting climate temperature is *** on the monitoring of body temperature,the changes in clothing pattern color can reflect people’s health and emotional *** the same time,it can also be applied to the screening of abnormal body temperature during the COVID-19.

关键词： Clean energy temperature variable materials wearable clothing design

来源：评论

学校读者我要写书评

暂无评论

Synthesis, characterization, crystal structure and DFT study of 1,1-diisopropyl-3-(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)urea

引用

MOLECULAR CRYSTALS AND LIQUID CRYSTALS 2023年第1期759卷 70-79页

作者： Wu, Feng Liu, Tong Liao, Wanpeng Zhou, Zhixu dai, hongyu Guizhou Univ Sch Chem & Chem Engn Guiyang 550025 Peoples R China Guizhou Engn Lab Synthet Drugs Guiyang 550025 Peoples R China Guizhou Univ Sch Pharmaceut Sci Guiyang 550025 Peoples R China

1,1-Diisopropyl-3-(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)urea was given by two-steps method, then the single crystal was measured by using X-ray diffraction. According to density functional theory (DFT) by using the 6-311 +/- G (2d, p) basis set, the optimized structure of the molecule was calculated with the B3LYP method, then the calculated value was compared with the value of X-ray diffraction. The analysis of optimized conformation by DFT indicated that the crystal structure was consistent with single crystal by X-ray diffraction. Finally, DFT was used to study the molecular electrostatic potential and frontier molecular orbitals of the title compound, which revealed its physicochemical properties.

关键词： analysis Arylurea DFT diffraction single crystal Synthesis X-ray

来源：评论

学校读者我要写书评

暂无评论

Synthesis, crystal structure, density functional theory and vibration analysis of 5-(4-fluorophenyl)-1H-pyrazol-3-amine

引用

MOLECULAR CRYSTALS AND LIQUID CRYSTALS 2023年第1期764卷 145-158页

作者： Wen, Kunqing dai, hongyu Mao, Yunhong Zhou, Zhixu Huang, Zhuyan Guizhou Univ Sch Pharmaceut Sci Guiyang Peoples R China Guizhou Engn Lab Synthet Drugs Guiyang Peoples R China

A pyrazole ring derivative 5-(4-fluorophenyl)-1H pyrazole-3-amine was synthesized. The title compound was characterized by H-1 NMR, C-13 NMR, MS, FT-IR, and single crystal X-ray diffraction. The optimized molecular crystal structure was determined by B3LYP/6-311 + G(2d, p) functional method and based on density functional theory (DFT) calculation. Hirshfeld surface analysis illustrates the study of non-covalent interactions in the title compound. The molecular electrostatic potential (MEP) and major molecular orbitals (FMOs) of the title compounds were analyzed by computational method. Finally, infrared vibration analysis was performed on the target compound.

关键词： 5-(4-Fluorophenyl)-1H-pyrazol-3-amine crystal structure DFT synthesis

来源：评论

学校读者我要写书评

暂无评论

Anesthesia/surgery-induced learning and memory dysfunction by inhibiting mitophagy-mediated NLRP3 inflammasome inactivation in aged mice

引用

EXPERIMENTAL BRAIN RESEARCH 2024年第2期242卷 417-427页

作者： Lu, Jian Zong, Youming Tao, Xiaoyan dai, hongyu Song, Jiale Zhou, Hongmei Jiaxing Univ Hosp Jiaxing 2 Affiliated Hosp 2 Dept Anesthesiol Jiaxing Zhejiang Peoples R China Jiaxing Univ Hosp Jiaxing 2 Affiliated Hosp 2 Dept Nursing Jiaxing Zhejiang Peoples R China

Postoperative cognitive dysfunction (POCD) is a common postoperative complication, not only affects the quality of life of the elderly and increases the mortality rate, but also brings a greater burden to the family and society. Previous studies demonstrated that Nod-like receptor protein 3 (NLRP3) inflammasome participates in various inflammatory and neurodegenerative diseases. However, possible mitophagy mechanism in anesthesia/surgery-elicited NLRP3 inflammasome activation remains to be elucidated. Hence, this study clarified whether mitophagy dysfunction is related to anesthesia/surgery-elicited NLRP3 inflammasome activation. POCD model was established in aged C57BL/6 J mice by tibial fracture fixation under isoflurane anesthesia. Morris Water Maze (MWM) was used to evaluate learning and memory abilities. We found that in vitro experiments, lipopolysaccharide (LPS) significantly facilitated NLRP3 inflammasome activation and mitophagy inhibition in BV2 cells. Rapamycin restored mitophagy and improved mitochondrial function, and inhibited NLRP3 inflammasome activation induced by LPS. In vivo experiments, anesthesia and surgery caused upregulation of hippocampal NLRP3, caspase recruitment domain (ASC) and interleukin-1 beta (IL-1 beta), and downregulation of microtubule-associated protein light chain 3II (LC3II) and Beclin1 in aged mice. Olaparib inhibited anesthesia/surgery-induced NLRP3, ASC, and IL-1 beta over-expression in the hippocampus, while upregulated the expression of LC3II and Beclin1. Furthermore, Olaparib improved cognitive impairment in older mice. These results revealed that mitophagy was involved in NLRP3 inflammasome-mediated anesthesia/surgery-induced cognitive deficits in aged mice. Overall, our results suggested that mitophagy was related in NLRP3 inflammasome-induced cognitive deficits after anesthesia and surgery in aged mice. Activating mitophagy may have clinical benefits in the prevention of cognitive impairment induced by anesthesia and s

关键词： Postoperative cognitive deficit Mitophagy Aged mice NLRP3 Neuroinflammation

来源：评论

学校读者我要写书评

暂无评论

Anthocyanin treatment delays the senescence of blueberry fruit by regulating abscisic acid and anthocyanin synthesis processes

引用

Food Quality and Safety 2024年第3期8卷 556-564页

作者： hongyu dai Bin Li Zichong Song Jinlong Tian Baodong Wei Xushu Lang Qian Zhou College of Food Shenyang Agricultural UniversityShenyangChina

Objectives:The purpose of this work was to examine the general effects of exogenous anthocyanins treatment on the synthesis of abscisic acid(ABA)and anthocyanin in blueberry fruit during postharvest storage under room temperature *** and Methods:Fresh blueberry fruit were treated with 3.0 g/L anthocyanins and stored at room temperature to investigate the effects of the treatment on fruit firmness and nutritional *** fruit firmness,ABA content,anthocyanin content and the relative expression levels of key genes were ***:The results demonstrated that anthocyanins treatment decreased the ABA level by inhibiting the expression of the VcNCED1 gene implicated in ABA *** the same time,the treatment increased the content of endogenous anthocyanin by promoting the expression of anthocyanin biosynthesis genes such as VcC4H,VcF3H,VcF3’5’H,VcANS,and ***:Postharvest anthocyanins treatment promoted the synthesis of endogenous anthocyanin,inhibited the accumulation of endogenous ABA,and delayed the senescence of blueberries by inhibiting fruit softening and the accumulation of active oxygen.

关键词： Blueberry softening abscisic acid anthocyanins storage

来源：评论

学校读者我要写书评

暂无评论

Modeling and Fault Analysis for Power Conditioning System of Giant Solid-State Laser Facility

引用

IEEE TRANSACTIONS ON PLASMA SCIENCE 2022年第2期50卷 366-373页

作者： Shen Hao dai hongyu Wang Shengwu Lee Li Kai Yang Huazhong Univ Sci & Technol Sch Elect & Elect Engn Wuhan 430074 Peoples R China

Power conditioning system (PCS), which provides matched pulse energy for the amplifier, is the key subsystem of a giant solid-state laser facility. It consists of many power conditioning modules (PCMs). Some of the catastrophic faults such as capacitor short-circuit, high voltage cable head short-circuit, or high and low voltage busbar short-circuit, might occur when there is high voltage in the PCMs. To analyze these cases, first, the model of a PCM was proposed. Second, three main faults of a PCM were introduced and the models of them were built. Third, a PCM experimental device with ten xenon lamps in parallel was designed and built, and the experimental results verified the effectiveness of the proposed model. In this article, three fault simulation results were analyzed and the security design recommendations were presented, which can provide reference value for the design of such power system.

关键词： Phase change materials Capacitors Circuit faults Discharges (electric) Inductance Xenon Inductors Fault analysis power conditioning module solid-state laser facility

来源：评论

学校读者我要写书评

暂无评论

Facile fabrication of polydopamine nanosphere-decorated fabric for solar steam generation

引用

TEXTILE RESEARCH JOURNAL 2022年第19-20期92卷 3451-3461页

作者： He, Mantang dai, hongyu Wang, Liming Qin, Xiaohong Yu, Jianyong Donghua Univ Coll Text Key Lab Text Sci & Technol Minist Educ Shanghai 201620 Peoples R China Donghua Univ Innovat Ctr Text Sci & Technol Shanghai Peoples R China

Solar steam generation has been regarded as a promising technology to obtain clean water from wastewater or seawater through converting incident sunlight to heat. Fabrics can be easily combined with many photothermal materials by various methods and possess a unique porous structure for efficient water transport and vapor diffusion. Herein, a solar steam generator with a rough surface based on novel polydopamine nanospheres grown onto fabric (PDANSs@fabric) is designed and fabricated by a one-step method. Consequently, the developed evaporator could achieve a water evaporation rate of 1.48 kg m(-2) h(-1) under 1 sun illumination. Moreover, the as-prepared PDANSs@fabric-based solar steam generator keeps a close level of water evaporation performance after washing for 30 min, exhibiting good stability and washability in steam generation. In addition, the designed evaporator can be applied in various water conditions, including seawater, dye wastewater and heavy metal ion wastewater, offering great inspiration in the ?elds of seawater desalination, wastewater treatment and energy collection.

关键词： Photothermal fabric solar steam generation polydopamine nanospheres washability seawater desalination wastewater treatment

来源：评论

学校读者我要写书评

暂无评论

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

请选择保存的检索档案：

请选择收藏分类：

通借通还

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：