检索结果-内蒙古大学图书馆

内蒙古大学学报（自然科学版） 2022年第1期53卷 92-97页

作者：张朋张露文郭改枝内蒙古师范大学计算机科学技术学院呼和浩特010020 南方医科大学卫生管理学院广州510000

随着我国快速的人口老龄化和疾病谱的变化情况,为预防多重慢性病的发生并提高中老年人生活质量,同时更好地实现健康中国2030,以中国健康与养老追踪调查(China Health and Retirement Longitudinal Study,简称CHARLS)数据为基础,选择性... 详细信息

随着我国快速的人口老龄化和疾病谱的变化情况,为预防多重慢性病的发生并提高中老年人生活质量,同时更好地实现健康中国2030,以中国健康与养老追踪调查(China Health and Retirement Longitudinal Study,简称CHARLS)数据为基础,选择性别、年龄、城乡分布、是否识字、婚姻状态及慢病情况等多维变量,使用Python编程进行统计及卡方检验,分析中老年人多重慢病患者疾病构成和多重慢病的组合,得到多重慢病的患病率与人口年龄和城乡分布有关。该研究结果希望可以引起人们对慢病及多重慢病的高度关注,提升居民健康意识,同时为减轻政府医疗卫生支出提出一些合理的建议。

关键词：慢性病多重疾病中国健康与养老追踪调查 Python

来源：评论

学校读者我要写书评

暂无评论

The effect of multimorbidity on functional limitations and depression amongst middle-aged and older population in China: a nationwide longitudinal study

引用

AGE AND AGEING 2021年第1期50卷 190-197页

作者： Zhao, Yang William Haregu, Tilahun Nigatu He, Li Lu, Shurong Katar, Ameera Wang, Haipeng Yao, Zhibin zhang, luwen Univ Melbourne Melbourne Sch Populat & Global Hlth Melbourne Vic Australia Peking Univ Hlth Sci Ctr George Inst Global Hlth Beijing Peoples R China Beijing Normal Univ Coll Phys Educ & Sport Beijing Peoples R China Shandong Univ Sch Hlth Care Management Jinan Peoples R China Shandong Univ NHC Key Lab Hlth Econ & Policy Res Jinan Peoples R China Sun Yat Sen Univ Zhongshan Sch Med Dept Anat & Neurobiol Guangzhou Peoples R China Southern Med Univ Sch Hlth Serv Management Guangzhou Peoples R China

Background: multimorbidity contributes to a large portion of the disease burden in low- and middle-income countries. However, limited research has been undertaken in China. This study has investigated the prevalence of multimorbidity and the associations of multimorbidity with activities of daily living (ADL), instrumental activities of daily living (IADL) and depression in China. Methods: the study participants included 10,055 adults aged 45 years and older from three rounds of the China Health and Retirement Longitudinal Study 2011-2015. Random-effects logistic regression models were used to examine the association of multimorbidity with ADL limitation, IADL limitation and mental disease. Results: the prevalence of multimorbidity amongst adults in China aged 45 years and older was 62.1% in 2015. The prevalence of multimorbidity was increased with older age, among women, in a higher socio-economic group and in the most deprived regions. Multimorbidity is associated with an increased likelihood of experiencing ADL limitation (adjusted odds ratio [AOR]=5.738, 95% confidence intervals (CI)=5.733, 5.744) and IADL limitation (AOR=2.590, 95% CI=2.588, 2.592) and depression (AOR=3.352, 95% CI=3.350, 3.354). Rural-urban disparities in functional difficulties and depression were also found amongst patients with multimorbidity. Conclusions: the burden of multimorbidity is high in China, particularly amongst the older population. Multimorbidity is associated with higher levels of functional limitations and depression. China healthcare reforms should introduce integrated care models and patient-centred healthcare delivery. The increasing need for reorientation of healthcare resources considering the distribution of multimorbidity and its adverse effect requires more attention from health policymakers in China and other developing countries.

关键词： multimorbidity functional limitation depression older people longitudinal study

来源：评论

学校读者我要写书评

暂无评论

黄河流域水污染跨部门协同治理的问题检视及法律保障

引用

河北环境工程学院学报 2024年第3期34卷 32-39,62页

作者：张露文史玉成甘肃政法大学环境法学院甘肃兰州730070

黄河流域生态环境脆弱,水资源短缺,河流纳污能力较弱,水污染呈现复合性特征。由于流域具有系统性、关联性、动态性特征,单一政府部门独立治理无法解决流域整体水污染问题。应积极探索跨部门联动、多方配合的协同治理模式。当前,协同治... 详细信息

黄河流域生态环境脆弱,水资源短缺,河流纳污能力较弱,水污染呈现复合性特征。由于流域具有系统性、关联性、动态性特征,单一政府部门独立治理无法解决流域整体水污染问题。应积极探索跨部门联动、多方配合的协同治理模式。当前,协同治理的相关法律供给不足、部门利益冲突、数据信息共享滞缓、行政体制分割、生态保护补偿制度激励性不足等问题是实现跨部门协同治理的主要阻碍。应以“整体主义”思维完善综合性立法,明确部门职权划分的同时,健全协同治理体制和责任共担机制、统一部门治理目标、利用大数据技术建立信息共享平台,畅通数据循环,完善生态保护补偿制度,激发部门参与协同治理的主动性。

关键词：黄河流域协同治理跨部门水污染

来源：评论

学校读者我要写书评

暂无评论

Abnormalities of Regional Brain Activity in Patients With Schizophrenia: A Longitudinal Resting-State fMRI Study

引用

SCHIZOPHRENIA BULLETIN 2023年第5期49卷 1336-1344页

作者： Li, Xue Liu, Qing Chen, Zhaonian Li, Yalin Yang, Ying Wang, Xiujuan Guo, Xiaoge Luo, Binbin zhang, Yan Shi, Han zhang, luwen Su, Xi Shao, Minglong Song, Meng Guo, Suqin Fan, Lingzhong Yue, Weihua Li, Wenqiang Lv, Luxian Yang, Yongfeng Xinxiang Med Univ Henan Mental Hosp Dept Psychiat Affiliated Hosp 2 Xinxiang Peoples R China Xinxiang Med Univ Henan Key Lab Biol Psychiat Xinxiang Peoples R China Int Joint Res Lab Psychiat & Neurosci Henan Xinxiang Peoples R China Chinese Acad Sci Inst Automat Brainnetome Ctr Beijing Peoples R China Chinese Acad Sci Inst Automat Natl Lab Pattern Recognit Beijing Peoples R China Peking Univ Inst Mental Hlth Beijing Peoples R China Minist Hlth Key Lab Mental Hlth Beijing Peoples R China Henan Collaborat Innovat Ctr Prevent & treatment m Xinxiang Peoples R China Xinxiang Med Univ Affiliated Hosp 2 388 Jianshe Middle Rd Xinxiang 453002 Peoples R China

Background Evidence from functional and structural research suggests that abnormal brain activity plays an important role in the pathophysiology of schizophrenia (SZ). However, limited studies have focused on post-treatment changes, and current conclusions are inconsistent. Study Design We recruited 104 SZ patients to have resting-state functional magnetic resonance imaging scans at baseline and 8 weeks of treatment with second-generation antipsychotics, along with baseline scanning of 86 healthy controls (HCs) for comparison purposes. Individual regional homogeneity (ReHo), amplitude of low-frequency fluctuations (ALFF), and degree centrality values were calculated to evaluate the functional activity. The Positive and Negative Syndrome Scale (PANSS) and MATRICS Consensus Cognitive Battery were applied to measure psychiatric symptoms and cognitive impairment in SZ patients. Results Compared with HCs at baseline, SZ patients had higher ALFF and ReHo values in the bilateral inferior temporal gyrus, inferior frontal gyrus, and lower ALFF and ReHo values in fusiform gyrus and precuneus. Following 8 weeks of treatment, ReHo was increased in right medial region of the superior frontal gyrus (SFGmed) and decreased in the left middle occipital gyrus and the left postcentral gyrus. Meanwhile, ReHo of the right SFGmed was increased after treatment in the response group (the reduction rate of PANSS >= 50%). Enhanced ALFF in the dorsolateral of SFG correlated with improvement in depressive factor score. Conclusions These findings provide novel evidence for the abnormal functional activity hypothesis of SZ, suggesting that abnormality of right SFGmed can be used as a biomarker of treatment response in SZ.

关键词： schizophrenia regional homogeneity resting-state functional magnetic resonance imaging prediction treatment response

来源：评论

学校读者我要写书评

暂无评论

Prediction of antipsychotic drug efficacy for schizophrenia treatment based on neural features of the resting-state functional connectome

引用

TRANSLATIONAL PSYCHIATRY 2025年第1期15卷 1-9页

作者： Liu, Song Wang, Meng Han, Weiyi Chen, Anran Liu, Xuzhen Liu, Kang Li, Xue Chen, Yi zhang, luwen Liu, Qing Guo, Xiaoge Wang, Xiujuan Kang, Ning Han, Yong Li, Yuanbo Su, Xi Lv, Luxian Liu, Bing Li, Wenqiang Yang, Yongfeng Xinxiang Med Univ Henan Mental Hosp Affiliated Hosp 2 Dept Psychiat Xinxiang 453002 Peoples R China Xinxiang Med Univ Int Joint Res Lab Psychiat & Neurosci Henan Henan Key Lab Biol Psychiat Xinxiang 453002 Peoples R China Henan Collaborat Innovat Ctr Prevent & Treatment M Xinxiang 453002 Peoples R China Beijing Normal Univ State Key Lab Cognit Neurosci & Learning Beijing 100875 Peoples R China Henan Acad Innovat Med Sci Brain Inst Zhengzhou 450000 Peoples R China Henan Engn Res Ctr Phys Diagnost & Treatment Techn Xinxiang 453002 Peoples R China

Neuroimaging studies have identified a large number of biomarkers associated with schizophrenia (SZ), but there is still a lack of biomarkers that can predict the efficacy of antipsychotic medication in SZ patients. The aim of this study was to identify neuroimaging biomarkers of antipsychotic drug response among features of the resting-state connectome. Resting-state functional magnetic resonance scans were acquired from a discovery cohort of 105 patients with SZ at baseline and after 8 weeks of antipsychotic medication treatment. Baseline clinical status and post-treatment outcome were assessed using the Positive and Negative Symptom Scale (PANSS), and clinical improvement was rated by the total score reduction. Based on acquired imaging data, a resting-state functional connectivity matrix was constructed for each patient, and a connectome-based predictive model was subsequently established and trained to predict individual PANSS total score reduction. Model performance was assessed by calculating Pearson correlation coefficients between predicted and true score reduction with leave-one-out cross-validation. Finally, the generalizability of the model was tested using an independent validation cohort of 52 SZ patients. The model incorporating resting-state connectome characteristics predicted individual treatment outcomes in both the discovery cohort (prediction vs. truth r = 0.59, mean squared error (MSE) = 0.021) and validation cohort (r = 0.41, MSE = 0.036). The model identified four positive features and eight negative features, which were respectively correlated positively and negatively with PANSS total score reduction. Among these positive features, the specific connections within the parietal lobe played a crucial role in the model's predictive performance. As for the negative features, they included the frontoparietal control network and the cerebello-thalamo-cortical connections. This study discovered and validated a set of functional features based on re

关键词：

来源：评论

学校读者我要写书评

暂无评论

外科植入物用α+β钛合金金相检验国内外标准对比分析

引用

金属热处理 2024年第6期49卷 277-281页

作者：李帆高娜张露文郭琳琳娄贵张博山东省医疗器械和药品包装检验研究院山东济南250101 国家药品监督管理局生物材料器械安全性评价重点实验室山东济南250101 山东省医疗器械生物学评价重点实验室山东济南250101

对比分析了国内外外科植入物标准中对钛合金显微组织的要求,GB/T 13810—2017中板材的显微组织要求原始β晶粒应充分破碎,不准许存在连续的晶界α相,棒材和丝材的显微组织应符合该标准中图A.1(a~i)。ISO 5832-3、ASTM F136和ASTM F1472... 详细信息

对比分析了国内外外科植入物标准中对钛合金显微组织的要求,GB/T 13810—2017中板材的显微组织要求原始β晶粒应充分破碎,不准许存在连续的晶界α相,棒材和丝材的显微组织应符合该标准中图A.1(a~i)。ISO 5832-3、ASTM F136和ASTM F1472的最新版中都规定显微组织应为在转变β基体上分布着等轴和/或拉长的初生α相,在原始β晶界上无连续的网状α相,其中ISO 5832-3中棒材的横向显微组织还要求符合ISO 20160中的A1~A9。结合钛合金的热机械加工工艺,热加工和再结晶的温度足够低于β转变温度,或者缓慢冷却时,将得到高体积分数的初生α相和晶间β相,在接近β转变温度下进行再结晶处理,将得到转变β基体上均匀分布着的等轴初生α相,表现为标准图谱中的A1~A9。在β相转变温度以上进行再结晶处理,将得到粗大的β晶粒间存在连续的晶界α、网状α、片状α相,表现为标准图谱中的A10~A24。

关键词： TC4合金显微组织国内外标准热处理

来源：评论

学校读者我要写书评

暂无评论

A bullet hole recognition method based on visual detection

A bullet hole recognition method based on visual detection

引用

Robotics, Automation and Intelligent Control (ICRAIC), International Conference on

作者： Fengjie Yu Shibin Song Jie Zhu Weihao Cheng Wenshuo Wu luwen zhang Xiaojie Jiang College of Electrical Engineering and Automation Shandong University of Science and Technology Qingdao China Yantai Tulan Electronic Technology Co. Ltd Yantai City China

Shooting Intelligent Detection System has important applications in the military industry. Existing target shooting systems mainly face problems such as high cost, complex operation, and poor environmental adaptability. Considering the above limitations, in this paper we propose a fast, low-cost, and easy-to-deploy bullet hole recognition algorithm based on visual detection, which mainly consists of four parts: image preprocessing, extraction of target center, bullet hole extraction and ring value determination. In the process of bullet hole extraction, a method for segmenting effective target surface is proposed to cope with the problem of off-target bullet holes. Our method can not only accurately localize the bullet holes, but also obtain the exact ring value at that location. In addition, due to the robust adaptability of our method, it can even be applied to outdoor scenarios.

关键词：

来源：评论

学校读者我要写书评

暂无评论

淮河流域地表水污染与癌症的空间关联

引用

中国医学科学院学报 2024年第6期46卷 849-861页

作者：赵婧韩伟郭晓波张璐雯薛芳姜晶梅中国医学科学院基础医学研究所、北京协和医学院基础学院流行病与卫生统计学系北京100005 中国医学科学院、北京协和医学院环境与健康科学中心北京100005

目的揭示淮河流域关键污染物的空间聚集模式,并基于污染分级进一步量化非消化道癌症风险和癌症负担,为淮河流域水污染的深化治理提供靶目标和数据支持。方法选取淮河流域2021年地表水质及2019年肿瘤登记年报的7种癌症发病数据,采用随机... 详细信息

目的揭示淮河流域关键污染物的空间聚集模式,并基于污染分级进一步量化非消化道癌症风险和癌症负担,为淮河流域水污染的深化治理提供靶目标和数据支持。方法选取淮河流域2021年地表水质及2019年肿瘤登记年报的7种癌症发病数据,采用随机森林-SHapley加性解释分析筛选关键污染物,基于空间分析划分污染分级,并计算其癌症风险和人群归因分数。结果筛选出5个关键污染物,分别为总磷、总氮、化学需氧量、5日生化需氧量及砷,并将其联合效应划分为3个污染分级,结果显示与低污染地区相比,高污染地区的5种癌症发病风险显著增加,包括肺癌(RR=1.26,95%CI=1.06~1.50)、乳腺癌(女性)(RR=1.46,95%CI=1.21~1.77)、胰腺癌(RR=1.46,95%CI=1.06~2.01)、脑癌(RR=1.44,95%CI=1.05~1.98)和胆囊癌(RR=1.60,95%CI=1.03~2.50),且人群归因分数几乎均超过5%。结论地表水污染的潜在癌症风险和负担不容忽视,唯有各行业密切合作,通过进一步制定政策法规、加强环境治理和进行公众健康干预,才能从根本上应对这一挑战。

关键词：淮河流域地表水污染空间分布模式污染分级癌症

来源：评论

学校读者我要写书评

暂无评论

制造业投入数字化与生产链长度

引用

经济经纬 2024年第3期41卷 94-107页

作者：周宏伟庞素勤刘曙光张露文南开大学经济学院天津300071 华中科技大学经济学院湖北武汉430074 中国海洋大学经济学院山东青岛266100

利用1995—2018年OECD世界投入产出与跨国—行业面板数据,实证检验了制造业投入数字化对生产链长度的影响。研究发现:第一,制造业投入数字化显著延长了生产链长度;第二,异质性检验显示,制造业投入数字化对发展中国家、资本密集型行业和... 详细信息

利用1995—2018年OECD世界投入产出与跨国—行业面板数据,实证检验了制造业投入数字化对生产链长度的影响。研究发现:第一,制造业投入数字化显著延长了生产链长度;第二,异质性检验显示,制造业投入数字化对发展中国家、资本密集型行业和全球价值链上游行业以及纯国内生产活动的影响更为明显,并且国外投入数字化对生产链长度的正向影响要小于国内投入数字化;第三,机制检验显示,制造业投入数字化主要通过扩大中间品进口数量和提高中间品进口质量延长生产链长度;第四,进一步分析表明,消费需求潜力规模能够增强制造业投入数字化对生产链长度的正向影响,而消费需求潜力结构无明显影响,制造业投入数字化在延长生产链长度的过程中存在显著的“行业扩散效应”。研究结论对构建内循环为主、外循环赋能的新发展格局具有重要启示。

关键词：投入数字化生产链长度中间品进口消费需求潜力行业扩散效应

来源：评论

学校读者我要写书评

暂无评论

mCPBA-mediated dioxygenation of unactivated alkenes for the synthesis of 5-imino-2-tetrahydrofuranyl methanol derivatives

引用

TETRAHEDRON LETTERS 2020年第50期61卷 152620-152620页

作者： Deng, Xiaojun zhang, luwen Liu, Huixia Bai, Yu He, Wei Fourth Mil Med Univ Sch Pharm Dept Chem Xian 710032 Peoples R China

A mCPBA-mediated, metal-free, intramolecular dioxygenation reaction of unactivated alkenes is reported. In the presence of m-chlorobenzoic peracid, different unsaturated amide substrates could be cyclized via epoxide intermediates, producing the corresponding 5-imino-2-tetrahydrofuranyl methanol products in up to 94% yield at room temperature. (C) 2020 Elsevier Ltd. All rights reserved.

关键词： Metal-free mCPBA 1,2-Diol Dioxygenation Pentenamides

来源：评论

学校读者我要写书评

暂无评论

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

请选择保存的检索档案：

请选择收藏分类：

通借通还

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：