It is well-known that the activated thin-layer capping covering by secondary capping of contaminated sediment poses a threat to the inactivation of activated material. In this study, the static simulation experiment w...
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It is well-known that the activated thin-layer capping covering by secondary capping of contaminated sediment poses a threat to the inactivation of activated material. In this study, the static simulation experiment was conducted to study the effect of secondary capping thickness by sediment on the control of TP release from the sediment by aluminum-based P-inactivation agent (Al-PIA), and to propose the phosphorus adsorption pathway of Al-PIA. The results showed that Al-PIA could effectively reduce the release of phosphorus pollutants from the sediment at the capping intensity of 2 kg/m(2). When the secondary capping thickness of sediment were 0, 2, 4, 7, 10, and 15 mm, the average removal rates of TP were 87.57%, 76.39%, 61.22%, 51.32%, 41.93%, and 32.11%, respectively, indicating that the removal efficiency of phosphorus decreased with the increase of the secondary capping thickness of the sediment. The adsorbed phosphorus by Al-PIA was mainly non-apatite inorganic phosphorus (NAIP) in inorganic phosphorus. With the increase of the secondary capping thickness of sediment, the NAIP proportion of phosphorus adsorbed by Al-PIA increased. Meanwhile, the removal rate of phosphorus in the activated capping system showed a first increase and then decrease trend, and the removal rates of total phosphorus (TP), inorganic phosphorus (IP), and organic phosphorus (OP) were obvious except for that of organic phosphorus (OP).
Objective This study was performed to explore the function and mechanism of Dvl3 in RA-FLS by exosome intervention. Methods The expression pattern of Dvl3 was examined by IHC, WB, and qPCR. Modified exosomes obtained ...
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Objective This study was performed to explore the function and mechanism of Dvl3 in RA-FLS by exosome intervention. Methods The expression pattern of Dvl3 was examined by IHC, WB, and qPCR. Modified exosomes obtained from culturing supernatant of RA-FLS infected with Dvl3 over expression (OE) lentivirus were administrated to the target RA-FLS. The ability of survival, migration, and the production of inflammatory factor influenced by exosomal Dvl3 were detected by CKK8 kits, Tunel, migration test, qPCR, and enzyme-linked immunosorbent assay (EliSA) respectively;Flow cytometry analysis was conducted to explorer the inflammatory moderate role of exosomes on CD4+ T cells. The possible downstream pathways of Dvl3 were screened by qPCR and WB and verified by double luciferase reporter experiment. Results The expression level of Dvl3 was significantly increased in RA and CIA. Exosomes from the OE group could significantly promote cell proliferation activity, migration/invasion ability. The augment of TNF-alpha, IL-1 beta, IL-17, and IL-21 was observed in exosomal Dvl3-OE group. Th1 and Th17 cells polarisation and cytokines related were both enhanced by Exosomal Dvl3. Over expression of Dvl3 was accompanied by the significant increase of beta-catenin and RhoA activities. Conclusion This study discovered the high expression of Dvl3 of exosomes derived from RA patients which may possessed the ability to promote phenotypic transformation of RA-FLS through Wnt pathway.
Aim: To construct a network structure for cognitive emotion regulation among Chinese undergraduate nursing students and identify central nodes and to explore the bridge connections between cognitive emotion regulation...
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Aim: To construct a network structure for cognitive emotion regulation among Chinese undergraduate nursing students and identify central nodes and to explore the bridge connections between cognitive emotion regulation strategies and professional identity from the perspective of network analysis. Background: Undergraduate nursing students are currently in a poor psychological condition and cognitive emotion regulation strategies can help them use positive approaches to regulate their emotions. There may be a link between cognitive emotion regulation strategies and professional identity. Design: This was a cross-sectional study that used network analysis. Method: A total of 218 Chinese undergraduate nursing students were selected and surveyed using the Cognitive Emotion Regulation Questionnaire and the Professional Identity Questionnaire. A network analysis model was constructed and the related indices were calculated using R 4.3.0 software. Results: Network analysis showed that the central nodes of undergraduate nursing students' cognitive emotion regulation strategies were positive reappraisal, refocusing on planning and catastrophising;In the bridge network of cognitive emotion strategies and professional identity, professional self-concept, positive reappraisal, benefits of stay and risk of resignation and refocusing on planning were the nodes with the strongest bridge strength. Conclusion: The salient central and bridge nodes can serve as potential targets for interventions aimed at improving the mental health of undergraduate nursing students. Nursing educators must be trained in cognitive emotion regulation and appropriately guided to use positive emotion regulation strategies in their studies and work. Educators should focus on the relation between cognitive emotion regulation and professional identity to improve the mental health of nursing students and stabilise the nursing workforce.
The incorporating of metalloid elements into the interstices of Pd lattice is a powerful strategy to manipulate the binding strength of surface adsorbates and thereby to boost its electrocatalytic activity and anti-po...
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The incorporating of metalloid elements into the interstices of Pd lattice is a powerful strategy to manipulate the binding strength of surface adsorbates and thereby to boost its electrocatalytic activity and anti-poisoning for many electrocatalytic reactions. In present work, a novel nanocomposite, the boron-incorporated palladium nanoparticles anchored on the three-dimensional nitrogen-doped graphene (PdBx/NG), was firstly fabricated through a simple hydrothermal synthesis followed by a facile wet chemical reduction method. Extensive physicochemical analyses were conducted to unveil the effects of the boron-incorporation on the properties of the assynthesized electrocatalyst. More strikingly, the PdBx/NG displayed considerably boosted electrocatalytic behavior towards glycerol oxidation reaction (GOR), which largely outperformed the Pd/NG and benchmark Pd/ C. The NG endowed PdBx/NG with three-dimensional architecture, rich pores and abundant nitrogen-containing functional groups. Furthermore, the boron-incorporation enabled the electronic effect (electronic modification) and strain effect (lattice expansion) for Pd. The superior contribution of NG and boron-incorporation enhanced electrocatalytic activity and reinforced stability of PdBx/NG for GOR. This study provides an alternative way for fabricating the boron-incorporated catalysts for electrochemical reactions and beyond.
Purpose This work aimed to (i) investigate the effect of hydraulic retention time (HRT) on controlling the release of phosphorus from sediment and (ii) interpret the phosphorus migration and transformation mechanism i...
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Purpose This work aimed to (i) investigate the effect of hydraulic retention time (HRT) on controlling the release of phosphorus from sediment and (ii) interpret the phosphorus migration and transformation mechanism in the Al-PHOSLOCK thin-layer capping system. Methods A 35-day laboratory dynamic simulation experiment was conducted by applying the Al-PHOSLOCK thin-layer capping to evaluate the effect of HRT on interrupting the release of phosphorus from contaminated sediments. The total phosphorus (TP), inorganic phosphorus (IP), organic phosphorus (OP), non-apatite inorganic phosphorus (NAIP), and apatite phosphorus (AP) were identified as different phosphorus species and analyzed during the experiment to further elucidate the migration and transformation of phosphorus. Results and discussion The release of phosphorus from contaminated sediment was successfully suppressed by the Al-PHOSLOCK capping layer with an efficiency of higher than 90%. The HRT exerted a dual role on phosphorus controlling: at low HRT, slight water flow facilitated phosphorus migrating out from sediment and diffusing to the overlying water;at high HRT, the migration of phosphorus from overlying water back to sediment was strengthened. It was demonstrated that the phosphorus release was effectively controlled by the Al-PHOSLOCK thin-layer capping under different HRT conditions (static, 0.5 d, 1.0 d, and 3.0 d). The mechanism of phosphorus migration and transformation in the Al-PHOSLOCK thin-layer capping system was elucidated, including three significant stages of physical interception, adsorption, and capture/hold/transform process. Conclusion This study verified the good capacity of the Al-PHOSLOCK capping system for controlling the release of sediment phosphorus under different HRT. Therefore, it was expected to be a promising approach in the handling of water eutrophication.
limited light absorption and low charge separation rates are the main obstacles for graphitic carbon nitride- based photocatalysts. In terms of these defects, an ordered-porous graphitic carbon nitride composites (PCN...
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limited light absorption and low charge separation rates are the main obstacles for graphitic carbon nitride- based photocatalysts. In terms of these defects, an ordered-porous graphitic carbon nitride composites (PCN@CNT) modified with truncated carbon nanotubes (CNTs) were composited through hydrothermalcalcination method in this work. Due to their electron trapping ability, the CNTs can enhance visible light absorption, narrow the bandgap, and act as electron concentrators, achieving that spatial separation of photo- generated carriers can inhibit electron-hole pair recombination efficiently. In addition, a controllable ordered- porous structure was constructed to provide abundant active sites and mass transfer channels, shortening the carrier migration path. These two modifications acted synergistically to enhance the catalysts' performance. The top-performing sample in this work, PCN@CNT-1, showed significant improvement in photovoltaic performance and achieved a 97.7 % degradation of rhodamine B, with a photocatalytic degradation rate constant (k k-value) more than three times that of PCN. This work demonstrates the potential for modification by coupling CNTs to design carbon-nitride-based photocatalysts with excellent catalytic performance, which can be used as catalysts for wastewater purification.
We used data from 441 managers of science and technology enterprises to empirically test the dynamic capability path and resource-based path of ability-enhancing, motivation-enhancing and opportunity-enhancing (AMO) s...
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We used data from 441 managers of science and technology enterprises to empirically test the dynamic capability path and resource-based path of ability-enhancing, motivation-enhancing and opportunity-enhancing (AMO) strategic human resource management as influencing factors on performance. The results show that AMO-enhancing strategic human resource management affects organizational performance through organizational emotional capability and organizational intellectual capital in the start-up stage. In the development stage, ability- and opportunity-enhancing strategic human resource management affects performance through organizational emotional capability and organizational intellectual capital, while motivation-enhancing strategic human resource management has no significant impact on performance. In the mature stage, ability-enhancing strategic human resource management influences performance through organizational emotional capability, while motivation- and opportunity-enhancing strategic human resource management has no significant effect on performance.
Objective To investigate the association between stroke and the risk for mortality among coronavirus disease 2019 (COVID-19) patients. Methods We performed systematic searches through electronic databases including Pu...
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Objective To investigate the association between stroke and the risk for mortality among coronavirus disease 2019 (COVID-19) patients. Methods We performed systematic searches through electronic databases including PubMed, Embase, Scopus, and Web of Science to identify potential articles reporting adjusted effect estimates on the association of stroke with COVID-19-related mortality. To estimate pooled effects, the random-effects model was applied. Subgroup analyses and meta-regression were performed to explore the possible sources of heterogeneity. The stability of the results was assessed by sensitivity analysis. Publication bias was evaluated by Begg's test and Egger's test. Results This meta-analysis included 47 studies involving 7,267,055 patients. The stroke was associated with higher COVID-19 mortality (pooled effect = 1.30, 95% confidence interval (CI): 1.16-1.44;I-2 = 89%, P < 0.01;random-effects model). Subgroup analyses yielded consistent results among area, age, proportion of males, setting, cases, effect type, and proportion of severe COVID-19 cases. Statistical heterogeneity might result from the different effect type according to the meta-regression (P = 0.0105). Sensitivity analysis suggested that our results were stable and robust. Both Begg's test and Egger's test indicated that potential publication bias did not exist. Conclusion Stroke was independently associated with a significantly increased risk for mortality in COVID-19 patients.
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