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Characteristics of grafted monocrystalline Si/β-Ga2O3 p-n heterojunction

APPLIED PHYSICS LETTERS 2024年第26期124卷 262101-262101页

作者： Gong, Jiarui Kim, Donghyeok Jang, Hokyung Alema, Fikadu Wang, Qingxiao Zhou, Jie Li, Yiran Ng, Tien Khee Qiu, Shuoyang Liu, Yang Sheikhi, Moheb Lu, Yi Singh, Ranveer Su, Xin Abbasi, Haris Naeem lin, Qinchen Xie, shuwen Chabak, Kelson Jessen, Gregg Cheung, Clincy Gambin, Vincent Pasayat, Shubhra S. Osinsky, Andrei Ooi, Boon S. Gupta, Chirag Ma, Zhenqiang Univ Wisconsin Madison Dept Elect & Comp Engn Madison WI 53706 USA Agnitron Technol Inc Chanhassen MN 55317 USA King Abdullah Univ Sci & Technol Dept Elect & Comp Engn Thuwal 239556900 Saudi Arabia Air Force Res Lab Dayton OH 45433 USA Northrop Grumman Corp Redondo Beach CA 21090 USA

Beta-phase gallium oxide (beta-Ga2O3) has exceptional electronic properties with vast potential in power and radio frequency electronics. Despite the excellent demonstrations of high-performance unipolar devices, the lack of effective p-type dopants in beta-Ga2O3 has hindered the further development of Ga2O3-based bipolar devices. In this work, we applied the semiconductor grafting approach and fabricated monocrystalline Si/beta-Ga(2)O(3)p-n heterojunctions, of which the characteristics were systematically studied. The heterojunctions demonstrated a diode rectification over 1.3 x 10(7) at +/- 2 V with a diode ideality factor of 1.13. Furthermore, capacitance-voltage (C-V) measurement showed frequency dispersion-free characteristics from 10 to 900 kHz. The interface defect density (D-it) was calculated as 1-3 x 10(12)/cm(2) eV. Scanning transmission electron microscopy (STEM) and x-ray photoelectron spectroscopy (XPS) revealed that an ultrathin oxygen-rich layer existed on the Ga2O3 surface and later formed an ultrathin interfacial layer after bonding with Si. It is speculated that the excessive oxygen at the Ga2O3 surface enhanced the passivation of the Si dangling bonds and thus reduced D-it. This work improved our understanding of interface properties of the semiconductor grafting approach, providing useful guidance on the future development of Si/Ga2O3 heterojunction devices.

关键词： Gallium compounds

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CAS-FGOALS Datasets for the Two Interglacial Epochs of the Holocene and the Last Interglacial in PMIP4

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Advances in Atmospheric Sciences 2020年第10期37卷 1034-1044页

作者： Weipeng ZHENG Yongqiang YU Yihua LUAN shuwen ZHAO Bian HE Li DONG Mirong SONG Pengfei lin and Hailong LIU State Key Laboratory of Numerical Modeling for Atmospheric Sciences and Geophysical Fluid Dynamics Institute of Atmospheric PhysicsChinese Academy of SciencesBeijing 100029China College of Earth and Planetary Sciences University of Chinese Academy of SciencesBeijing 100049China Climate Change Research Center Chinese Academy of SciencesBeijing 100029China Chinese Academy of Sciences Center for Excellence in Tibetan Plateau Earth Sciences Beijing 100101China

Two versions of the Chinese Academy of Sciences Flexible Global Ocean-Atmosphere-Land System model(CASFGOALS),version f3-L and g3,are used to simulate the two interglacial epochs of the mid-Holocene and the Last Interglacial in phase 4 of the Paleoclimate Modelling Intercomparison Project(PMIP4),which aims to study the impact of changes in orbital parameters on the Earth’s *** the PMIP4 experimental protocols,four simulations for the mid-Holocene and two simulations for the Last Interglacial have been completed,and all the data,including monthly and daily outputs for the atmospheric,oceanic,land and sea-ice components,have been released on the Earth System Grid Federation(ESGF)*** datasets contribute to PMIP4 and CMIP6(phase 6 of the Coupled Model Intercomparison Project)by providing the variables necessary for the two interglacial *** this paper,the basic information of the CAS-FGOALS models and the protocols for the two interglacials are briefly described,and the datasets are validated using proxy *** suggest that the CAS-FGOALS models capture the large-scale changes in the climate system in response to changes in solar insolation during the interglacial epochs,including warming in mid-to-high latitudes,changes in the hydrological cycle,the seasonal variation in the extent of sea ice,and the damping of interannual variabilities in the tropical ***,disagreements within and between the models and the proxy data are also *** datasets will help the modeling and the proxy data communities with a better understanding of model performance and biases in paleoclimate simulations.

关键词： PMIP4 CMIP6 CAS-FGOALS interglacials orbital parameters

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A stochastic SIRS epidemic model with non-monotone incidence rate under regime-switching

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JOURNAL OF THE FRANKlin INSTITUTE-ENGINEERING AND APPLIED MATHEMATICS 2019年第16期356卷 9844-9866页

作者： Lan, Guijie lin, Ziyan Wei, Chunjin Zhang, shuwen Jimei Univ Sch Sci Xiamen Fujian Peoples R China

In this paper, we propose and discuss a stochastic SIRS epidemic model with non-monotone incidence rate under regime-switching. First of all, we show that there is a unique positive solution, which is a prerequisite for analyzing the long-term behavior of the stochastic model. Then, a threshold dynamic determined by the basic reproduction number R-0(s) is established: the disease can be eradicated almost surely if R-0(s) < 1 and under mild extra conditions, whereas if R-0(s) > 1, the densities of the distributions of the solution can converge in L-1 to an invariant density by using the Markov semigroups theory. Finally, based on realistic parameters obtained from previous literatures, numerical simulations have been performed to verify our analytical results. (C) 2019 The Franklin Institute. Published by Elsevier Ltd. All rights reserved.

关键词： Stochastic models

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Capillary electrophoretic method for Staphylococcus aureus detection by using a novel antimicrobial peptide

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ELECTROPHORESIS 2021年第11期42卷 1217-1220页

作者： Hong, Tingting Qiu, lin Rui, Wen Li, Ying Zheng, Ronghui Guo, Qianqian Zhou, shuwen Cui, Pengfei Sheng, Jingyu Ni, Xinye Wang, Jianhao Jiang, Pengju Changzhou Univ Sch Pharm Changzhou Jiangsu Peoples R China Jiangsu Sci Stand Med Testing Co Ltd Changzhou Jiangsu Peoples R China Jiangsu Traumark Med Instrument Co Ltd Changzhou Jiangsu Peoples R China Jiangsu Univ Wujin Hosp Changzhou Jiangsu Peoples R China Nanjing Med Univ Affiliated Changzhou Peoples Hosp 2 Changzhou Jiangsu Peoples R China Changzhou Le Sun Pharmaceut Co Ltd Changzhou Jiangsu Peoples R China

A novel peptide containing antimicrobial sequence and gelatinase cleavage sites was designed for Staphylococcus aureus detection. Since Staphylococcus aureus could secrete gelatinase, the fluorescein labeled peptide GKRWWKWWRRPLGVRGC could be recognized and cleaved. The obtained products were able to be analyzed by capillary electrophoresis with fluorescence detection. To explore the effect of Staphylococcus aureus concentration on enzyme digestion ability of peptide, Staphylococcus aureus with different concentrations were incubated with the peptide. Results indicated that capillary electrophoretic method was efficient for determining Staphylococcus aureus content. Compared with traditional approaches for Staphylococcus aureus detection, capillary electrophoresis possessed higher efficiency, enhanced sensitivity, and low sample consumption. Moreover, the proposed peptide also presented desirable antimicrobial activity. It suggested that the novel antimicrobial peptide used in this research opens a new path of detecting Staphylococcus aureus by capillary electrophoretic method.

关键词： Antimicrobial peptide Capillary electrophoresis Staphylococcus aureus

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基于神经网络和最近邻相似度的动臂实例检索

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机械制造与自动化 2018年第5期47卷 167-171页

作者：闫二乐高领付林述温林航福州大学机械工程及其自动化学院福建福州350108

为了参照已有的设计实例实现工程机械的快速设计,缩短产品的设计周期,提出基于神经网络和最近邻相似度的方案检索策略。先对过去历史的设计实例进行结构性分解,选择适当的属性特征;再运用概率神经网络对实例进行分类,缩小二次检索的范围... 详细信息

为了参照已有的设计实例实现工程机械的快速设计,缩短产品的设计周期,提出基于神经网络和最近邻相似度的方案检索策略。先对过去历史的设计实例进行结构性分解,选择适当的属性特征;再运用概率神经网络对实例进行分类,缩小二次检索的范围;最后针对动臂结构参数多、最近邻法的权重系数设置难点,提出专家经验知识和客观数据相结合的方法,计算各个实例与目标实例的相似度,并以一个设计需求进行实例推理验证基于实例推理方法的准确性和有效性。

关键词：工程机械快速设计初始方案设计基于实例推理神经网络最近邻距离法相似度

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An improved total least square calibration method for straightness error of coordinate measuring machine

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PROCEEDINGS OF THE INSTITUTION OF MECHANICAL ENGINEERS PART B-JOURNAL OF ENGINEERING MANUFACTURE 2016年第9期230卷 1665-1672页

作者： Gu, Tianqi lin, shuwen Fang, Bing Luo, Tianzhi Fuzhou Univ Coll Mech Engn & Automat Fuzhou Peoples R China Fujian Agr & Forestry Univ Coll Mech & Elect Engn Fuzhou 350002 Peoples R China

The total least square method based on singular value decomposition for fitting straight line and plane surface has been developed to deal with the straightness calibration problem. Different from the ordinary least square method only taking into account the error of the dependent variable, total least square method considers the errors of all the variables in a symmetrical way. However, in practice, it is difficult to choose an optimal method for the variable errors of measurement data in an asymmetric way. This article presents an improved calibration method for straightness error of a coordinate measuring machine. The proposed method, named as improved total least square, could fit straight line and plane surface when the variables are in an asymmetric way. In improved total least square method, weight matrices with parameter set between the independent and dependent variables are introduced to augmented matrix. A procedure is developed to determine the parameter . Numerical cases and measurement experiment are given to prove the performance of improved total least square method.

关键词： Straightness calibration ordinary least square total least square coordinate measuring machine

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Effect of PCL concentration on PCL/CaSiO3 porous composite scaffolds for bone engineering

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CERAMICS INTERNATIONAL 2020年第9期46卷 13082-13087页

作者： Shao, Huiping Yu, Xinding lin, Tao Peng, Jiang Wang, Aiyuan Zhang, Zhinan Zhang, Yumeng Liu, shuwen Zhao, Manjian Univ Sci & Technol Beijing Inst Adv Mat & Technol Beijing 100083 Peoples R China Chinese Peoples Liberat Army Gen Hosp Inst Orthoped Beijing 100853 Peoples R China Key Lab Musculoskeletal Trauma & War Injuries PLA Key Lab Regenerat Med Orthoped Beijing 100853 Peoples R China

Porous polycaprolactone (PCL)-coated calcium silicate (CaSiO3) composite scaffolds were successfully prepared by 3D gel-printing (3DGP) and vacuum impregnation technology in this study. The effect of different PCL concentration on porous CaSiO3 scaffolds prepared by 3DGP technology was studied. The composition and morphological characteristics of PCL/CaSiO3 scaffolds were tested by using fourier transform infrared spectroscopy (FTIR), scanning electron microscope (SEM), and energy dispersive spectrometer (EDS) analysis. PCL coating amount on the scaffolds surface was calculated by thermogravimetric analysis (TGA). Compressive strength was tested by a universal testing machine, and degradability was tested by immersing the scaffolds in a simulated body fluid (SBF). The results show that PCL coating thickness increased from 7.29 mu m to 12.2 mu m and the compressive strength of the corresponding composite scaffolds increased from 17.15 MPa to 24.12 MPa following with PCL concentration increasing from 7.5% to 12.5%. When the porous composite scaffolds were immersed in SBF for 28 days, the degradation ratio was 1.06% (CaSiO3), 1.63% (CaSiO3-7.5PCL), 1.81% (CaSiO3-10PCL) and 1.55% (CaSiO3-12.5PCL), respectively. It is obviously that PCL/CaSiO3 composite scaffolds, which are suitable for bone growth in bone repair engineering, are beneficial to improve the mechanical properties and biodegradability of pure CaSiO3 scaffolds.

关键词： PCL coating Vacuum impregnation Porous scaffolds CaSiO3 Biodegradability

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基于时序遥感影像的西南山区地块尺度作物类型识别

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地球信息科学学报 2023年第3期25卷 654-668页

作者：秦肖伟程博杨志平李林董文张新杨树文靳宗义薛庆兰州交通大学测绘与地理信息学院兰州730070 中国科学院空天信息创新研究院北京100094 重庆市农业信息中心重庆401121 地理国情监测技术应用国家地方联合工程研究中心兰州730070 甘肃省地理国情监测工程实验室兰州730070 北京师范大学地理科学学部北京100875

西南山区地块破碎且复杂,种植类型多样,且该地区多云多雨,可利用遥感数据有限,利用单一的光谱特征或植被指数难以实现作物的有效识别。物候特征能够反映作物的生长周期规律,可用于复杂地区作物的精细监测。本研究以重庆市潼南区为例,基... 详细信息

西南山区地块破碎且复杂,种植类型多样,且该地区多云多雨,可利用遥感数据有限,利用单一的光谱特征或植被指数难以实现作物的有效识别。物候特征能够反映作物的生长周期规律,可用于复杂地区作物的精细监测。本研究以重庆市潼南区为例,基于多时相中分辨率的Sentinel-2和Landsat8遥感影像,对地块尺度的NDVI、EVI等6个植被指数进行时间序列构建并提取其物候特征,通过特征优选构建多维数据,利用随机森林分类模型对柠檬、油菜、水稻、玉米等作物进行识别。结合植被指数与物候特征进行作物分类,总体精度达94.52%,Kappa系数为0.90,柠檬、油菜、玉米、水稻的精度分别为89.88%、87.30%、84.98%和95.57%。研究表明,利用时序遥感数据的植被指数与物候特征能够有效进行地块尺度的作物识别,为复杂种植结构地区获取大范围作物分布制图提供参考。

关键词：遥感时间序列地块尺度西南山区植被指数物候特征随机森林作物识别

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Dihydromyricetin is a new inhibitor of influenza polymerase PB2 subunit and influenza-induced inflammation

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MICROBES AND INFECTION 2020年第6-7期22卷 254-262页

作者： Tian, Yuanxin Sang, Huiting Liu, Miaomiao Chen, Fangzhao Huang, Yingna Li, lin Liu, shuwen Yang, Jie Southern Med Univ Guangdong Prov Key Lab New Drug Screening Guangzhou Key Lab Drug Res Emerging Virus Prevent Sch Pharmaceut Sci Guangzhou 510515 Peoples R China Guangdong Med Univ Sch Pharm Dongguan 523808 Peoples R China

Development of new and effective anti-influenza drugs is critical for the treatment of influenza virus infection. The polymerase basic 2 (PB2) subunit as a core subunit of influenza A virus RNA polymerase complex is considered to be an attractive drug target for anti-influenza drug discovery. Dihydromyricetin, as a natural flavonoid, has a wide range of biological activities, but its anti-influenza A virus activity is ambiguous. Here, we found dihydromyricetin could inhibit the replication of a variety of influenza A virus strains. Mechanism studies demonstrated that dihydromyricetin reduced viral polymerase activity via selective inhibition of viral PB2 subunit, and decreased relative amounts of viral mRNA and genomic RNA during influenza A virus infection. The binding affinity and molecular docking analyses revealed that dihydromyricetin interacted with the PB2 cap-binding pocket, functioned as a cap-binding competitor. Interestingly, dihydromyricetin also reduced cellular immune injury by inhibiting TLR3 signaling pathway. Additionally, combination treatment of dihydromyricetin with zanamivir exerted a synergistic anti-influenza effect. Altogether, our experiments reveal the antiviral and anti-inflammatory activities of dihydromyricetin in vitro against influenza virus infection, which provides a new insight into the development of novel anti-influenza drugs. (C) 2020 Institut Pasteur. Published by Elsevier Masson SAS. All rights reserved.

关键词： Dihydromyricetin Influenza A virus Influenza polymerase basic 2 Anti-inflammatory TLR3

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p-Terphenyls as Anti-HSV-1/2 Agents from a Deep-Sea-Derived Penicillium sp.

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JOURNAL OF NATURAL PRODUCTS 2021年第11期84卷 2822-2831页

作者： Chen, Weihao Zhang, Jiawen Qi, Xin Zhao, Kai Pang, Xiaoyan lin, Xiuping Liao, Shengrong Yang, Bin Zhou, Xuefeng Liu, shuwen Wang, Junfeng Yao, Xingang Liu, Yonghong Chinese Acad Sci South China Sea Inst Oceanol CAS Key Lab Trop Marine Bioresources & Ecol Guangzhou 510301 Peoples R China Chinese Acad Sci South China Sea Inst Oceanol Guangdong Key Lab Marine Mat Med Guangzhou 510301 Peoples R China Univ Chinese Acad Sci Beijing 100049 Peoples R China Southern Med Univ Sch Pharmaceut Sci State Key Lab Organ Failure Res Guangdong Prov Key Lab New Drug Screening Guangzhou 510515 Peoples R China Southern Marine Sci & Engn Guangdong Lab Guangzho Guangzhou 511458 Peoples R China Sanya Inst Oceanol Yazhou Sci Bay SCSIO Sanya 572000 Peoples R China

Guided by Global Natural Products Social molecular networking, two p-terphenyl derivatives and one 4,5-diphenyl-2-pyrone analogue, peniterphenyls A-C (1-3), together with five known p- terphenyl derivatives (4-8) and sulochrin (9), were obtained from a deep-sea-derived Penicillium sp. SCSIO41030. Their structures were elucidated using extensive NMR spectroscopic and HRESIMS data and by comparing the information with literature data. Peniterphenyl B (2) represented the first reported natural product possessing a 4,5-diphenylsubstituted 2-pyrone derivative. The p-terphenyl derivatives displayed inhibitory activities against HSV-1/2 with EC50 values ranging from 1.4 +/- 0.6 to 9.3 +/- 3.7 mu M in Vero cells, which showed that they possessed antiviral activities with low cytotoxicity, superior to the current clinical drug acyclovir (EC50 3.6 +/- 0.7 mu M). Peniterphenyl A (1) inhibited HSV-1/2 virus entry into cells and may block HSV-1/2 infection through direct interaction with virus envelope glycoprotein D to interfere with virus adsorption and membrane fusion, and thus differs from the nucleoside analogues such as acyclovir. Our study indicated peniterphenyl A (1) could be a promising lead compound against HSV-1/2.

关键词： Infectious diseases Antimicrobial agents Peptides and proteins Membranes Assays

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