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工矿自动化 2022年第6期48卷 69-76,111页

作者：张袁浩潘祥生陈晓晶霍振龙任书文季亮中煤科工集团常州研究院有限公司江苏常州213015 天地(常州)自动化股份有限公司江苏常州213015

介绍了智能选矸机器人应用与研究现状,指出目前智能选矸机器人主要基于X射线和图像识别原理,利用高压气动分拣和桁架机器人抓取进行煤矸分离;智能选矸机器人分拣执行机构主要有桁架式、并联式、串联式等类型,响应速度快,常常以“拨”和... 详细信息

介绍了智能选矸机器人应用与研究现状,指出目前智能选矸机器人主要基于X射线和图像识别原理,利用高压气动分拣和桁架机器人抓取进行煤矸分离;智能选矸机器人分拣执行机构主要有桁架式、并联式、串联式等类型,响应速度快,常常以“拨”和“抓”的形式分离矸石;在胶带运输过程中,智能选矸机器人“拨”需要考虑不同矸石尺寸的兼容性及运动路径的优化,“抓”需考虑机械手的作业空间及机器人的承载能力。分析了智能选矸机器人在现场复杂环境中有效实现矸石分拣的基于深度学习的煤矸识别、面向非结构多约束环境的选矸机械臂运动规划、基于力反馈的机械臂主动柔顺控制、多臂协作分拣任务分配策略及控制等关键技术,并指出基于深度学习的煤矸识别技术作为选矸机器人的关键技术之一,仍需在煤矸数据集高效构建方法、煤矸识别算法的泛化性提升及实时性优化等方面进行进一步研究。结合现场应用和机器人智能化发展需求,指出了智能选矸机器人今后的研究方向:针对现场复杂环境进行技术改进,提高煤矸识别算法的鲁棒性和自适应性;适应复杂环境的智能感知和控制技术及矸石高精度三维位姿估算技术的研究;基于力位混合控制的选矸机器人智能拣矸技术研发;智能选矸机器人井下选矸技术探究。

关键词：智能选矸机器人矸石分拣图像识别煤矸识别机械臂运动规划智能感知和控制任务分配策略

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老年患者术后自控镇痛效果的现状及影响因素分析

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中华疼痛学杂志 2025年第1期21卷 58-64页

作者：李提提王明明吴正男任抒文陈红芳周燕江苏大学附属人民医院护理部江苏省镇江市221000 苏州大学附属第二医院麻醉科苏州市215000 安徽医科大学附属安庆市立医院急危重症科安庆市246000

目的探讨老年患者术后自控镇痛效果的现状及影响因素。方法本研究为回顾性病例对照研究。采用病历查询方式,收集2023年8月1日至2024年1月31日,苏州大学附属第二医院全麻术后使用智能化自控镇痛的老年患者病例资料,年龄≥65岁,美国麻醉... 详细信息

目的探讨老年患者术后自控镇痛效果的现状及影响因素。方法本研究为回顾性病例对照研究。采用病历查询方式,收集2023年8月1日至2024年1月31日,苏州大学附属第二医院全麻术后使用智能化自控镇痛的老年患者病例资料,年龄≥65岁,美国麻醉医师协会(ASA)分级Ⅰ~Ⅲ级,对患者一般资料、术中及术后资料进行分析,根据患者术后24 h数字等级评分(NRS),分为无痛或轻度疼痛组(NRS<4分),中重度疼痛组(NRS≥4分)。通过logistic回归分析探讨术后镇痛的影响因素。结果最终纳入512例患者,其中中重度疼痛组127例,无痛或轻度疼痛组385例,中重度疼痛发生率为24.8%。多因素logistic回归分析结果显示,女性(OR=1.841,95%CI:1.210~2.802,P=0.004)、术毕返回病房NRS≥4分(OR=17.608,95%CI:1.965~157.802,P=0.010)、PCA错误按压(OR=1.801,95%CI:1.106~2.935,P=0.018)是老年患者术后自控镇痛效果不佳的危险因素,年龄≥75岁(OR=0.581,95%CI:0.345~0.980,P=0.042)、合并疾病≥3个(OR=0.616,95%CI:0.403~0.942,P=0.025)与老年患者术后自控镇痛效果不佳负相关。结论年龄、性别、合并疾病个数、术毕疼痛评分、PCA按压方法是老年患者术后自控镇痛效果的影响因素。

关键词：疼痛,手术后镇痛,病人控制老年人影响因素

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Advancing clinical cancer care: Unveiling the power of surface-enhanced Raman spectroscopy

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JOURNAL OF RAMAN SPECTROSCOPY 2024年第4期55卷 429-444页

作者： Li, Xue Yang, Guang Zhang, shuwen ren, He Harbin Med Univ Canc Hosp Dept Breast Surg Harbin Peoples R China Harbin Med Univ Affiliated Hosp 2 Dept Obstet & Gynaecol Harbin Peoples R China

Tumors are characterized by abnormal cell growth, which leads to uncontrolled cell proliferation, invasion of surrounding tissues, and potential metastasis to other parts of the body. Current treatments for tumors include surgery, chemotherapy, radiotherapy, targeted therapy, and biological therapy. However, many tumors are detected at advanced stages, limiting the effectiveness of these treatments. Therefore, there is a need to develop more sensitive and efficient techniques to improve patient survival rates. Surface-enhanced Raman scattering (SERS) technology is a highly sensitive molecular detection and characterization technique. It can be combined with histomorphology, immunolabeling assays, and molecular hybridization to achieve quantitative diagnosis at morphological, molecular, and genetic levels. SERS offers advantages such as objectivity, reproducibility, and comparability. However, there are challenges to address, including complex substrate or probe preparation, cumbersome data analysis, and signal reproducibility and reliability. To fully utilize the potential of SERS in the biomedical field and for clinical translation, it is important to optimize the technology and develop more sensitive, accurate, and reliable substrate or probe preparation and analysis methods. This review aims to comprehensively explain the mechanism and unique advantages of SERS technology and discuss its current status, challenges, and prospects in tumor-related research. The clinical applications of surface-enhanced Raman spectroscopy (SERS) for cancer diagnosis and treatment are illustrated. Key elements depicted include using SERS for noninvasive liquid biopsy, detecting tumor microenvironments, identifying precancerous lesions, guiding precision drug therapy, assisting in surgery and ablation, and monitoring prognosis. The image emphasizes SERS technology's potential and the need for optimization to enhance cancer patient ***

关键词： clinical applications diagnosis and treatment prognostic monitoring surface-enhanced Raman scattering (SERS) tumor

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1例立克次体感染合并爆发性心肌炎老年患者的护理体会

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中国老年保健医学 2025年第1期23卷 149-152页

作者：吴正男王明明赵荣华苏燕任抒文李提提江苏大学附属人民医院护理部 212003 安徽省安庆市立医院重症医学科 246001

本研究通过整理和总结1例立克次体感染合并爆发性心肌炎老年患者的护理过程,探讨老年危重患者的有效护理策略。护理要点如下:通过连续性肾脏替代治疗进行容量管理;高流量静脉-动脉体外膜肺氧合治疗时予持续抗凝监测,予消化道出血的处理... 详细信息

本研究通过整理和总结1例立克次体感染合并爆发性心肌炎老年患者的护理过程,探讨老年危重患者的有效护理策略。护理要点如下:通过连续性肾脏替代治疗进行容量管理;高流量静脉-动脉体外膜肺氧合治疗时予持续抗凝监测,予消化道出血的处理;加强管道的管理,保持流量正常和预防非计划脱管;评估患者呼吸功能,实施个性化气道廓清技术方案;多学科合作,实施各阶段渐进式肢体康复锻炼;目标导向性镇痛镇静,预防老年患者谵妄发生;通过预见性护理,防控发生院内感染。研究结果表明,老年立克次体感染合并爆发性心肌炎患者病情变化迅速、危重程度和病死率高,因此早期预测病情转归并及时进行多脏器替代治疗和护理,加强危重患者的康复锻炼,是降低患者死亡率和提高患者预后生活质量的重要途径。本案例为临床护理立克次体感染合并爆发性心肌炎老年患者提供了有价值的经验和参考。

关键词：立克次体感染爆发性心肌炎体外膜肺氧合治疗连续性肾脏替代治疗抢救重症监护

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肺癌术后患者恐惧疾病进展现状及心理机能失调预测模型构建

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中华保健医学杂志 2025年第2期27卷 257-261页

作者：吴正男王明明赵荣华任抒文李提提詹必成安庆市立医院重症医学科安庆246001 江苏大学附属人民医院护理部

目的调查肺癌术后患者恐惧疾病进展水平现状,分析其心理机能失调的影响因素,并构建预测模型。方法采取便利抽样法,前瞻性选取2023年1月~2024年1月于安庆市立医院行肺癌术治疗的385例患者作为训练集进行研究,采用一般资料调查问卷、疾... 详细信息

目的调查肺癌术后患者恐惧疾病进展水平现状,分析其心理机能失调的影响因素,并构建预测模型。方法采取便利抽样法,前瞻性选取2023年1月~2024年1月于安庆市立医院行肺癌术治疗的385例患者作为训练集进行研究,采用一般资料调查问卷、疾病进展恐惧量表(FoP-Q-SF)、焦虑自评量表(SAS)、抑郁自评量表(SDS)对患者进行调查,并根据FoP-Q-SF评分将患者分为心理机能失调组(≥34分)和非心理机能失调组(<34分)。采用单因素分析和多因素logistic回归分析其发生心理机能失调的相关因素,并构建预测模型,采用受试者工作特征(ROC)曲线下面积(AUC)和Hosmer-Lemeshow(H-L)验证模型的预测效果。验证集根据与训练集3∶7的比例,选取2024年2~7月于本院行肺癌术治疗的165例患者进行外部验证。结果训练集患者FoP-Q-SF评分为(34.51±6.24)分,其中生理健康维度评分为(18.27±4.26)分,社会家庭维度评分为(16.24±3.87)分;其中心理机能失调177例,发生率为45.97%。多因素logistic回归分析显示,女性、文化程度低、家庭平均月收入低、无配偶、SAS评分高、SDS评分高、肿瘤分期Ⅲ~Ⅳ期是肺癌术后患者发生心理机能失调的危险因素(P<0.05)。训练集H-L检验结果显示,χ^(2)=2.810,P=0.946,预测模型的AUC为0.887(95%CI=0.855~0.919,P<0.001),灵敏度为0.797,特异度为0.846。验证集H-L检验结果显示,χ^(2)=4.858,P=0.711,预测模型的AUC为0.892(95%CI=0.859~0.925,P<0.05),灵敏度为0.808,特异度为0.880。结论肺癌术后患者恐惧疾病进展水平较高,基于结果中女性、文化程度低、家庭平均月收入低、无配偶、SAS评分高、SDS评分高、肿瘤分期Ⅲ~Ⅳ期7个危险因素构建的预测模型具有较好的预测效能,能够有效为临床干预治疗提供参考,减少肺癌术后患者心理机能失调的发生。

关键词：肺癌术后恐惧疾病进展心理机能失调预测模型

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Effect of dual-channel structures on DC characteristics of vertical trench GaN-based MOSFETs

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SEMICONDUCTOR SCIENCE AND TECHNOLOGY 2025年第5期40卷 055007-055007页

作者： Yang, Fan Li, Xinxin ren, Yuke Li, Shuti Zheng, shuwen South China Normal Univ Sch Elect Sci & Engn Foshan Guangdong Peoples R China South China Normal Univ Guangdong Engn Res Ctr Optoelect Funct Mat & Devic Guangzhou Guangdong Peoples R China

In this work, five dual-channel vertical trench GaN-based metal oxide semiconductor field-effect transistors (MOSFETs) are proposed and studied. The dual-channel structures include dual two-dimensional electron gas (2DEG) structure, 2DEG and three-DEG (3DEG) hybrid structures, and dual 3DEG structure. Compared to the MOSFET with 2DEG from the abrupt GaN/Al0.3Ga0.7N heterostructure, the MOSFET with 3DEG from the graded AlxGa1-xN (0 <= x <= 0.3) layer can provide more channel electrons, and significantly improve the saturation current and reduce the on-resistance. By introducing three-dimensional hole gas as the current barrier layer to optimize the dual-3DEG channel vertical MOSFET, the saturation current of the optimized MOSFET is 2.8 times higher and the on-resistance is reduced by 53% to 1.11 m Omega center dot cm2 at Vgs = 12 V, and the breakdown voltage is increased from 955 V to 1510 V compared with traditional single-channel MOSFET. Therefore, the optimized dual-channel MOSFET has excellent DC characteristics and can be used as a high-power switching device in next-generation energy and communications applications.

关键词： GaN-based MOSFET dual-channel structures 2DEG 3DEG 3DHG

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Sea-Land Segmentation Algorithm Based on Multiframe Radar Echoes

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IEEE TRANSACTIONS ON GEOSCIENCE AND REMOTE SENSING 2023年 61卷 1页

作者： Xu, shuwen Bai, Xiaohui ren, Qinghui Li, Dongchen Xidian Univ Natl Key Lab Radar Signal Proc Xian 710071 Peoples R China Syst Engn Res Inst Beijing 100096 Peoples R China

In modern radar applications, data-driven sea-land segmentation of complex environments based directly on radar returns without the help of electronic charts and other information has attracted researchers' attention due to the solidification of exogenous information and defect of nonreal timeness. However, the sea-land segmentation based on radar echoes still faces two problems: first, complex clutter environment with mixed ground and sea clutter leads to a large dynamic range of clutter power, which makes power-based segmentation unreliable;and second, stable segmentation features are difficult to obtain when echoes in a single scan period are limited. In the case of multiframe radar echoes, this article first unwraps the phases of two adjacent echo sequences and extracts a new similarity measure for sea-land segmentation based on the covariance of phase difference sequences between sea clutter and ground clutter. Then, inspired by the idea of iteration, this article proposes a method to iterate the covariance matrix by iterating the clutter map of the characteristic differences of multiframe echoes to distinguish between sea and ground clutter more effectively. Experimental results based on the measured data show that the proposed sea-land segmentation method based on multiframe echoes can effectively separate sea and land areas and ensure the quality of the segmentation results, and after several consecutive scan periods, the proposed sea-land segmentation method is more accurate and robust than other sea-land segmentation methods.

关键词： Clutter Radar Radar clutter Image segmentation Spaceborne radar Radar imaging Object detection Clutter map multiframe radar echoes sea clutter sea-land segmentation

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基于5M1E分析法对重症监护室老年连续性肾脏替代治疗患者非计划下机的影响因素分析

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中国医药导报 2024年第31期21卷 126-131页

作者：吴正男王明明任抒文李提提赵荣华梅本刚苏燕江苏大学附属人民医院护理部江苏镇江212003 安徽省安庆市立医院重症医学科安徽安庆246001

目的基于5M1E分析法探讨重症监护室(ICU)老年连续性肾脏替代治疗(CRRT)患者非计划下机的影响因素。方法回顾性分析2022年1月至2023年11月安徽省安庆市立医院收治的157例(399次)ICU老年CRRT患者的临床资料,根据是否发生非计划下机,将其... 详细信息

目的基于5M1E分析法探讨重症监护室(ICU)老年连续性肾脏替代治疗(CRRT)患者非计划下机的影响因素。方法回顾性分析2022年1月至2023年11月安徽省安庆市立医院收治的157例(399次)ICU老年CRRT患者的临床资料,根据是否发生非计划下机,将其分为计划下机组(281次)和非计划下机组(118次)。对其发生现状和相关影响因素进行二分类logistic回归分析。结果ICU老年CRRT患者非计划下机发生率为29.5%。不同慢性基础病数量、治疗时间、诊断、治疗干预评分系统(TISS)评分、抗凝方式及是否治疗中血流量不足和是否治疗中跨膜压升高老年CRRT患者非计划下机情况比较,差异有统计学意义(P<0.05)。TISS评分(OR=1.267,95%CI:1.146~1.400)、治疗时间(OR=0.888,95%CI:0.842~0.936)、治疗中血流量不足(OR=36.501,95%CI:12.362~107.778)、治疗中跨膜压升高(OR=17.092,95%CI:7.461~39.154)、枸橼酸抗凝(OR=2.659,95%CI:1.339~5.280)、药物中毒(OR=4.582,95%CI:1.255~16.729)、特殊类型酸中毒(OR=3.601,95%CI:1.574~8.237)是老年CRRT患者非计划下机的独立影响因素(P<0.05)。结论TISS评分高、治疗中血流量不足、治疗中跨膜压升高、使用枸橼酸抗凝及治疗时间越短的药物中毒和特殊类型酸中毒老年患者,在ICU进行CRRT时非计划下机发生风险较高。

关键词：重症监护室老年连续性肾脏替代治疗非计划下机影响因素护理

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AIMP2 restricts EV71 replication by recruiting SMURF2 to promote the degradation of 3D polymerase

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Virologica Sinica 2024年第4期39卷 632-644页

作者： Junrui ren Lei Yu Qiuhan Zhang Pengyu ren Yumeng Cai Xueyun Wang Ke Lan shuwen Wu State Key Laboratory of Virology College of Life SciencesWuhan UniversityWuhan430072China Medical Research Institute Wuhan UniversityWuhan430072China Taikang Center for Life and Medical Sciences Wuhan UniversityWuhan430072China

Hand,foot and mouth disease(HFMD),mainly caused by enterovirus 71(EV71),has frequently occurred in the Asia-Pacific region,posing a significant threat to the health of infants and young ***,research on the infection mechanism and pathogenicity of enteroviruses is increasingly becoming *** 3D polymerase,as the most critical RNA-dependent RNA polymerase(RdRp)for EV71 replication,is widely targeted to inhibit EV71 *** this study,we identified a novel host protein,AIMP2,capable of binding to 3D polymerase and inhibiting EV71 *** investigations revealed that AIMP2 recruits the E3 ligase SMURF2,which mediates the polyubiquitination and degradation of 3D ***,the antiviral effect of AIMP2 extended to the CVA16 and CVB1 *** research has uncovered the dynamic regulatory function of AIMP2 during EV71 infection,revealing a novel antiviral mechanism and providing new insights for the development of antienteroviral therapeutic strategies.

关键词： AIMP2 Enterovirus 71(EV71) 3D polymerase E3 ligase SMURF2 Ubiquitination

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A Reduced Order Model for Arc Heat Transfer in Oil Based on POD-LSTM 5th

A Reduced Order Model for Arc Heat Transfer in Oil Based on ...

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5th International Symposium on Plasma and Energy Conversion, iSPEC 2023

作者： Zhang, shuwen ren, He Zhong, Linlin Suzhou215127 China School of Electric Engineering Southeast University Nanjing210096 China

ISBN: (纸本)9789819722440

In real-time simulation applications, the full-order model often necessitates lengthy computation times, rendering it inadequate to meet the demands of real-time performance. In pursuit of establishing a digital twin for predicting the arc temperature field within transformer oil, this paper introduces a reduced-order model capable of rapidly solving the temperature distribution. Initially, a full-order model of arc heat transfer within transformer oil is developed employing the finite volume method. Subsequently, Proper Orthogonal Decomposition (POD) is employed for feature analysis, followed by dimensionality reduction based on an energy ratio criterion to capture the predominant modes. Finally, a prediction model for each primary modal coefficient is constructed using a Long Short-Term Memory (LSTM) network. The effectiveness of this approach is demonstrated through numerical simulations of a two-dimensional arc heat transfer multiphase flow model. The results indicate that the calculation outputs from the reduced-order model meet the specified error criteria. Concurrently, the computational time is dramatically reduced from hours to seconds. This research underscores the accuracy and timeliness of the reduced-order model, enhancing computational efficiency while maintaining the precision of the digital twin model. © The Author(s), under exclusive license to Springer Nature Singapore Pte Ltd. 2024.

关键词： Finite volume method

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