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Preparation and characterization of infant formula concentrates: Simulation with human milk lipid composition and fat globule size and distribution

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JOURNAL OF FOOD ENGINEERING 2023年第1期359卷

作者： Zhao, Pu Lu, Jing Zhu, Huiquan Wu, Gangcheng Zhang, shuwen Lv, Jiaping wei, wei Wang, Xingguo Jiangnan Univ State Key Lab Food Sci & Resources Wuxi 214122 Peoples R China Jiangnan Univ Collaborat Innovat Ctr Food Safety & Qual Control Sch Food Sci & Technol Wuxi 214122 Peoples R China Beijing Technol & Business Univ Beijing Engn & Technol Res Ctr Food Addit Sch Food & Hlth Beijing Adv Innovat Ctr Food Nutr & Human Hlth Beijing 100048 Peoples R China Chinese Acad Agr Sci Key Lab Agrofood Proc & Qual Control Inst Food Sci & Technol Beijing 100193 Peoples R China

This study aims to prepare infant formula concentrates (IFs) simulating human milk fat globule (HMFG) composition, size and distribution. Mixed plant oil (21.3% palm oil, 2.8% flaxseed oil, 2.6% soybean oil, 29.9% rapeseed oil and 43.4% corn oil) and concentrated whey protein were applied to mimic triacylglycerols and phospholipids in HMFG respectively. IF1-IF6 were produced by different homogenization pressures or physically mixed with different proportions. IF4, prepared with 95% IF1 (4.29 mu m), 1% IF2 (0.497 mu m) and 4% IF3 (9.43 mu m), showed a mean particle size of 3.96 mu m and 49.77% milk fat globule membrane protein, and had the closest size distribution and interface with HMFG. The prepared IFs showed good stability with the Turbiscan stability index (IF6 (1.75)

关键词： Infant formula Lipid Milk fat globule Particle size distribution Microstructure Stability

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Bidirectional band-switchable nano-film absorber from narrowband to broadband

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OPTICS EXPRESS 2021年第4期29卷 5110-5120页

作者： Wang, Fei Gao, Huixuan Peng, wei Li, Rui Chu, shuwen Yu, Li Wang, Qiao Dalian Univ Technol Sch Phys Dalian 116024 Peoples R China Dalian Univ Technol Sch Optoelect Engn & Instrumentat Sci Dalian 116024 Peoples R China

We propose a switchable perfect absorber with broadband and narrowband absorption based on alternating dielectric and metal nano-film structures in this paper. The lithography-free pattern is equipped with polarization insensitivity, good ductility and manufacturability, which has great significance in practical device development and applications. The quasi-complete selective absorption of incident light can be originated from asymmetric Fabry-Perot resonance, which combines the destructive interference in dielectric layers with inherent absorption in metal layers. When the light incidents on the surface covered with ultra-thin metal film of this structure, it acts as a narrowband absorber with over 99.90% absorption at 771 nm wavelength and a full wave at half maximum of 20 nm. When the light incidents on other surfaces covered with anti-reflective dielectric film, it achieves broadband perfect absorption with an average absorption exceeding 96.02% in a 500-1450 nm wavelength range. The absorption spectrum of oblique incidence shows that the broadband absorption behaves big angle range tolerance while the narrowband absorption exhibits angular dependence. The band-switchable performance of this absorber makes it valuable for energy harvesting/re-radiation applications in solar thermal photovoltaic systems. (C) 2021 Optical Society of America under the terms of the OSA Open Access Publishing Agreement

关键词： Absorption spectroscopy Destructive interference Liquid crystals Phase matching Polarization Surfaces

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弱交流系统下光伏经柔直送出系统的稳定运行极限及提升方法

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电力自动化设备 2024年第10期44卷 39-45页

作者：赵薇郭春义张舒文彭茂兰冯雷华北电力大学新能源电力系统全国重点实验室北京102206 中国南方电网有限责任公司超高压输电公司检修试验中心广东广州510663

弱交流系统下大规模新能源接入的柔直系统的稳定运行范围影响着系统的新能源消纳能力。建立了弱交流系统下光伏经柔直送出系统的稳态数学模型与状态空间模型,综合考虑了系统稳态运行约束和小信号稳定性约束,提出了系统稳定运行区域的计... 详细信息

弱交流系统下大规模新能源接入的柔直系统的稳定运行范围影响着系统的新能源消纳能力。建立了弱交流系统下光伏经柔直送出系统的稳态数学模型与状态空间模型,综合考虑了系统稳态运行约束和小信号稳定性约束,提出了系统稳定运行区域的计算方法,定量评估了不同送端交流系统短路容量和光伏出力下系统稳态约束范围与小信号稳定性约束边界的变化特征。研究发现随着送端交流系统短路容量的降低与光伏出力的增大,小信号稳定性约束在稳态约束范围的基础上进一步限制了系统的稳定运行区域。通过特征值分析和参与因子分析,研究了影响弱交流系统下小信号稳定性的关键影响因素,提出了一种附加频率阻尼控制策略,由此在一定程度上扩大了系统稳定运行范围。在PSCAD/EMTDC中搭建了弱交流系统下光伏经柔直送出系统的仿真模型,验证了理论分析和计算结果的正确性。

关键词：弱交流系统光伏柔直系统稳定运行极限附加频率阻尼控制

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Bitrate Estimation for Spatial Scalable Videos

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IEEE TRANSACTIONS ON BROADCASTING 2021年第2期67卷 549-555页

作者： Jiang, Zhuqing wei, Likuo Zeng, Ganmin Qi, shuwen Wang, Haiying Men, Aidong Zhou, Yun Beijing Univ Posts & Telecommun Sch Artificial Intelligence Beijing Key Lab Network Syst & Network Culture Beijing 100876 Peoples R China Beijing Univ Posts & Telecommun Sch Artificial Intelligence Beijing 100876 Peoples R China Beijing Univ Posts & Telecommun Sch Informat & Commun Engn Beijing 100876 Peoples R China Acad Broadcasting Sci TV Technol Res Inst Beijing 100866 Peoples R China

Spatial scalable video service has surged in the time of multiple screens. Existing bitrate allocation methods are principled by rate-distortion theory and characterized by iterative encoding, which is accurate yet complex. However, the quasi-quantitative description is preferred in practice of broadcasting. In this paper, we propose a task of bitrate estimation for scalable videos concerning the content, aiming at a more efficient model at the cost of precision. First, we exhibit necessity to build a model for Scalable High Efficiency Video Coding (SHVC) and quantitative relation between video content and bitrate using different encoders. Then, a scalable-video dataset is prepared. It covers various types of content to offer diversity for model training. In the end, multi-linear regression is utilized to estimate the bitrate of scalable videos, with spatial and temporal indices as explanatory variables. Our statistical experiments show the model is able to estimate bitrate after trained on the self-built dataset.

关键词： Bit rate Videos Estimation Encoding Resource management Complexity theory Video coding SHVC bitrate estimation multi-linear regression

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半浸桨叶剖面的变参数水动力性能分析

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中国造船 2023年第2期64卷 115-125页

作者：常晟铭王超孙聪施书文魏豪中国船舶科学研究中心无锡214082 哈尔滨工程大学船舶工程学院哈尔滨150001

为了优化半浸桨叶剖面的设计,建立了一种半浸桨叶剖面的参数化建模方式,采用重叠网格技术和VOF自由液面捕捉技术对半浸桨叶剖面入水问题进行了数值模拟。在此基础上,通过控制半浸桨叶剖面杯型随边上、下表面的曲率和厚度,进行水动力性... 详细信息

为了优化半浸桨叶剖面的设计,建立了一种半浸桨叶剖面的参数化建模方式,采用重叠网格技术和VOF自由液面捕捉技术对半浸桨叶剖面入水问题进行了数值模拟。在此基础上,通过控制半浸桨叶剖面杯型随边上、下表面的曲率和厚度,进行水动力性能分析,绘制了半浸桨叶剖面设计图谱。分析表明,若增大半浸桨叶剖面的随边曲率或随边厚度,横向及垂向力系数会有所增大,敞水效率会降低;在下表面曲率一定的情况下,减小随边上表面曲率对半浸桨叶剖面入水过程的水动力特性有不利影响。

关键词：半浸桨参数化建模杯型随边高速入水数值模拟

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Identification of PDCD1 and PDCD1LG2 as Prognostic Biomarkers and Associated with Immune Infiltration in Hepatocellular Carcinoma

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INTERNATIONAL JOURNAL OF GENERAL MEDICINE 2022年 15卷 437-449页

作者： Li, Wang Mei, Mei Liu, Tian Zhang, shuwen Wang, ZeYu Suo, YuHong Wang, Shuai Liu, Yang Zhang, NingNing Lu, wei Tianjin Med Univ Key Lab Canc Prevent & Therapy Tianjin Med Univ Canc Inst & Hosp Natl Clin Res Ctr CancDept Hepatobiliary Oncol Tianjin 300060 Peoples R China Tianjin Med Univ NHC Key Lab Hormones & Dev Tianjin Key Lab Metab Dis Chu Hsienl Mem Hosp Tianjin 300134 Peoples R China Tianjin Med Univ Tianjin Inst Endocrinol Tianjin 300134 Peoples R China Tianjin Med Univ Grad Sch Tianjin 300070 Peoples R China Tianjin First Cent Hosp Tianjin 300192 Peoples R China Tianjin Haihe Hosp Dept Gastroenterol Tianjin 300350 Peoples R China

Background: Hepatocellular carcinoma has been identified to be among the most prevalent malignancies in the world and has an unfavorable prognosis. Immune checkpoints perform an essential function in many biological processes and are associated with the survival of cancer patients. The function of immune checkpoints remains unknown. Methods: We used bioinformatic methods to examine the prognostic value of immune checkpoints and the corresponding link to immune infiltration in HCC. qRT-PCR was used to validate the expression of immune checkpoints and their prognostic significance in HCC. Results: The level of mRNA of SIGLEC15, PDCD1LG2, LAGS, PDCD1, CTLA4 as well as PDCD1LG2 was increased in HCC tissues as opposed to liver tissues. Immune checkpoints were shown to participate in the activation of the apoptotic pathway in HCC patients. The elevated expression of PDCD1 and PDCD1LG2 were shown to have a favorable recurrence-free survival (RFS), progression-free survival (PFS), disease-specific survival (DSS), and overall survival (OS). PDCD1, PDCD1LG2, and pT stage were independent variables that affect the HCC patients' prognoses as revealed by the multivariate and univariate analyses. A prediction nomogram indicated that the calibration plots for OS rates over three and five years had a stronger predictive performance in the TCGA HCC cohort in contrast with an ideal model. Positive correlations were observed between the PDCD1 and PDCD1LG2 expression and immune biomarkers, immune cells, chemokine receptors, as well as chemokines. Conclusion: The present research performed a thorough examination of the prognostic significance of immune checkpoints in HCC and its correlation with immune infiltration, which suggested that PDCD1 and PDCD1LG2 were prognostic biomarkers in HCC and related to the immune infiltration.

关键词： HCC PDCD1 PDCD1LG2 immune checkpoints prognosis biomarker

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A novel fiber-optic surface plasmon resonance sialic acid nanosensor based on boronic-acid-functionalized Au NPs 12

A novel fiber-optic surface plasmon resonance sialic acid na...

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12th International Conference on Information Optics and Photonics (CIOP)

作者： Yuan, Huizhen Chu, shuwen Sun, Guangyi Li, Na Peng, wei Dalian Univ Technol Sch Phys Dalian 116024 Peoples R China Liaoning Prov Liaoyang Ecol & Environm Monitoring Liaoyang 111000 Peoples R China

ISBN: (数字)9781510649903

ISBN: (纸本)9781510649903;9781510649897

Sialic acid (SA) exists as a sialic acid complex and participates in a variety of important physiological functions of the body, such as cell recognition. The increase in the concentration of sialic acid in human biological samples exceeds the normal concentration and is related to the development of various cancers. The SPR based label-free detection of small targeted molecules is a great challenge and require substantial signal amplification for the accurate and precise quantification. We have developed an SA sensor based on boric acid fiber-optic SPR in the form of Sialic acid. The signal enhancement technology of 4-mercaptophenylboronic acid (MPBA) modified gold nanoprobe is used for the high-sensitivity detection of sialic acid. Under optimal conditions, the SA concentration has a linear relationship between 0.0001 and 1 mM. The detection limit reached 100 nM. Fiber-based SPR sensing technology not only has high sensitivity and detection, but also avoids damage to biological samples, which has a wide range of application potential in biological non-destructive sensing.

关键词： Fiber-optic surface plasmon resonance gold nanoparticles sialic acid boric acid

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Multi-center application of a convolutional neural network for preoperative detection of cavernous sinus invasion in pituitary adenomas

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NEURORADIOLOGY 2024年第3期66卷 353-360页

作者： Fang, Yi Wang, He Cao, Demao Cai, Shengyu Qian, Chengxing Feng, Ming Zhang, Wentai Cao, Lei Chen, Hongjie wei, Liangfeng Mu, shuwen Pei, Zhijie Li, Jun Wang, Renzhi Wang, Shousen Chinese Acad Med Sci & Peking Union Med Coll Peking Union Med Coll Hosp Dept Neurosurg 1 Shuai Fu Yuan Beijing 100730 Peoples R China Fujian Med Univ Fuzhou Hosp 900TH Fuzong Clin Med Coll Dept Neurosurg 156Xierhuanbei Rd Fuzhou Fujian Peoples R China Yangzhou Univ Affiliated Hosp Dept Neurosurg Yangzhou Jiangsu Peoples R China Fujian Med Univ Affiliated Hosp 2 Dept Neurosurg Quanzhou Peoples R China Tongling Peoples Hosp Dept Neurosurg Tongling Peoples R China Capital Med Univ Tiantan Hosp Dept Neurosurg Beijing Peoples R China Chinese Univ Hong Kong Shenzhen Sch Med Shenzhen Guangdong Peoples R China

ObjectiveCavernous sinus invasion (CSI) plays a pivotal role in determining management in pituitary adenomas. The study aimed to develop a Convolutional Neural Network (CNN) model to diagnose CSI in multiple *** total of 729 cases were retrospectively obtained in five medical centers with (n = 543) or without CSI (n = 186) from January 2011 to December 2021. The CNN model was trained using T1-enhanced MRI from two pituitary centers of excellence (n = 647). The other three municipal centers (n = 82) as the external testing set were imported to evaluate the model performance. The area-under-the-receiver-operating-characteristic-curve values (AUC-ROC) analyses were employed to evaluate predicted performance. Gradient-weighted class activation mapping (Grad-CAM) was used to determine models' regions of *** CNN model achieved high diagnostic accuracy (0.89) in identifying CSI in the external testing set, with an AUC-ROC value of 0.92 (95% CI, 0.88-0.97), better than CSI clinical predictor of diameter (AUC-ROC: 0.75), length (AUC-ROC: 0.80), and the three kinds of dichotomizations of the Knosp grading system (AUC-ROC: 0.70-0.82). In cases with Knosp grade 3A (n = 24, CSI rate, 0.35), the accuracy the model accounted for 0.78, with sensitivity and specificity values of 0.72 and 0.78, respectively. According to the Grad-CAM results, the views of the model were confirmed around the sellar region with *** deep learning model is capable of accurately identifying CSI and satisfactorily able to localize CSI in multicenters.

关键词： Pituitary Adenoma Deep Learning Cavernous sinus Invasion

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The stationary distribution and ergodicity of a stochastic phytoplankton-zooplankton model with toxin-producing phytoplankton under regime switching

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PHYSICA A-STATISTICAL MECHANICS AND ITS APPLICATIONS 2020年 537卷 122728-000页

作者： Chen, Zhewen Tian, Zhuyan Zhang, shuwen wei, Chunjin Jimei Univ Sch Sci Xiamen Fujian Peoples R China

This paper addresses a stochastic phytoplankton-zooplankton model with toxin-producing phytoplankton under regime switching. The stochastic model in this paper includes white and colored noises. For the model, we first prove the existence of the global positive solution of the model. And then by using Khasminskii's method and Lyapunov function, we derive sufficient conditions for the existence of a unique ergodic stationary distribution. Finally, numerical simulations are carried out to support our results. (C) 2019 Elsevier B.V. All rights reserved.

关键词： Toxin-producing phytoplankton Phytoplankton-zooplankton Regime switching Positive recurrent Environmental fluctuations

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Anti-thermal-quenching red-emitting phosphors based on lanthanide doped negative-thermal-expansion (NTE) hosts

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JOURNAL OF LUMINESCENCE 2022年 242卷 118536-118536页

作者： Wang, wei Fu, Meiqian Liu, shuwen Zhang, Xinyang wei, Yi Li, Guogang China Univ Geosci Fac Mat Sci & Chem Engn Res Ctr Nanogeomat Minist Educ 388 Lumo Rd Wuhan 430074 Peoples R China

Thermal quenching (TQ) is still a critical challenge for phosphor materials (especially for red phosphors) in white light emitting diodes lighting applications. Herein, we put forward an effective method to design anti-TQ red emission of Eu3+ in the unique negative-thermal-expansion (NTE) orthorhombic Sc2(Mo,W)3O12 hosts. Surprisingly, the emission intensity of Sc2Mo3O12:Eu3+ (SMO:Eu3+) is enhanced to 150% of initial intensity at 150 degrees C and 123% of initial intensity at 200 degrees C under blue light excitation. Similarly, the Sc2W3O12:Eu3+ (SWO: Eu3+) also could exhibit 123% of initial intensity at 150 degrees C and 106% at 200 degrees C. According to the variabletemperature X-ray diffraction and photoluminescence results, the unique anti-TQ phenomenon should be ascribed to the improved structural rigidity induced by the contraction of cell volumes and energy transfer from traps. By employing a 380 nm UV chip, the as-fabricated white LEDs using Sc2Mo3O12:Eu3+ phosphor presents a warm white light with CIE color coordinates (0.3112, 0.3198), low corresponding color temperature (CCT = 5045 K), and high color rendering index (CRI = 90.6). This work initiates a novel strategy to construct anti-TQ red-emitting phosphors for multiple practical optical applications.

关键词： Anti-thermal-quenching Natigative thermal expansion Red phosphors White light emitting diodes

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