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SSRN 2022年

作者： Chen, Xiaoxuan xu, shuwen Hu, Shaohai Ma, Xiaole Beijing Key Laboratory of Advanced Information Science and Network Technology Beijing100000 China School of Computer and Information Technology Beijing Jiaotong Universitys Beijing100000 China Research Institute of TV and Electro-Acoustics Beijing100000 China

Though the deep learning-based method has demonstrated strong capabilities on image fusion, they usually improve the fusion performance by increasing the width and depth of the network, increasing the computational effort and being unsuitable for industrial application. In this paper, an end-to-end multi-modal image fusion network based on discrete Chebyshev moments fixed convolution module is proposedto deal with this problem, which does not need any pre- or postprocessing. The proposed network is roughly composed of three parts: feature extraction module, fusion module and feature reconstruction module. In the feature extraction module, one discrete Chebyshev moments fixed convolution module is proposed to obtain different frequency components in a short time. To improve the image sharpness and obtain more details, a spatial attention mechanism based on average gradient is proposed in fusion module. Extensive results demonstrate that the proposed network achieves remarkable fusion performance, high time efficiency and strong generalization ability. © 2022, The Authors. All rights reserved.

关键词： Image fusion

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Semi-Automatic Extraction of the Threshold Segmentation of Coastline Based on Coastline Type

Semi-Automatic Extraction of the Threshold Segmentation of C...

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2020 International Symposium on Water, Ecology and Environment, ISWEE 2020

作者： Yu, Tan xu, shuwen Zhou, Xinyu Xiao, Jiajun Zhang, Bingxu College of Marine Sciences Shanghai Ocean University Shanghai201306 China

Using remote sensing images to extract the shoreline is an important means of studying coastlines. In this paper, we propose a semi-automatic coastline extraction method based on the coastline type that uses region segmentation and edge detection image processing. Based on selected Landsat 4-5 TM and Landsat 8 OLI_TIRS satellite images of Chongming Island from 1985 to 2017, we find that the point control method, neighborhood marking method, and targeted selection based on different shoreline types significantly improve the calculation efficiency, have good adaptability, and produce highly accurate shoreline extraction. © Published under licence by IOP Publishing Ltd.

关键词： Landsat

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Noisy Remote Sensing Image Fusion Based on JSR

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IEEE ACCESS 2020年 8卷 31069-31082页

作者： Ma, Xiaole Hu, Shaohai Liu, Shuaiqi Wang, Jie xu, shuwen Beijing Jiaotong Univ Inst Informat Sci Beijing 100044 Peoples R China Beijing Jiaotong Univ Beijing Key Lab Adv Informat Sci & Network Techno Beijing 100044 Peoples R China Hebei Univ Coll Elect & Informat Engn Baoding 071000 Peoples R China Hebei Univ Machine Vis Engn Res Ctr Hebei Prov Baoding 071000 Peoples R China Res Inst TV & Electroacoust Beijing 100015 Peoples R China

Compressed sensing has shown great potential and power in image representation, especially in image reconstruction by sparse representation. Due to complementary information and unavoidable noise existing in synthetic aperture radar (SAR) and other source images, joint sparse representation (JSR) is developed to separate redundancy and complementary information with different properties in source images and obtain a fused image, where image de-noising is done simultaneously owing to that noise is not sparse and cannot be represented by sparse representation. As a result, one noisy remote sensing image fusion method based on JSR is presented in this paper. After obtaining redundant and complementary sub-images by JSR, an improved fusion rule based on pulse coupled neural network (PCNN) is employed to fuse complementary sparse coefficients together. At the same time, because the types of noise in SAR and other source images are different, they can be treated as the complementary information in source images and suppressed at this step. Finally, a fused image can be reconstructed by adding the redundant and fused complementary sub-images. Quantitative and qualitative experimental results show that the proposed method outperforms most of other fusion methods and it is more robust to noise, having better visual effects and values of objective evaluation metrics.

关键词： Remote sensing image fusion joint sparse representation pulse coupled neural network SAR image processing

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Effects of miR-202-5p silencing PIK3CA gene expression on proliferation, invasion, and epithelial-mesenchymal transition of cervical cancer SiHa cells through inhibiting PI3K/Akt/mTOR signaling pathway activation

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MOLECULAR AND CELLULAR BIOCHEMISTRY 2021年第11期476卷 4031-4044页

作者： Zheng, Yan Xie, Lei xu, shuwen Yan, Weidong Zhang, Hongzhen Meng, Yali Liu, Jingqiao Wei, xujing Hebei Med Univ Hosp 1 Dept Gynecol & Obstet 89 Donggang Rd Shijiazhuang 050031 Hebei Peoples R China Army Engn Univ Training & Res Support Ctr Shijiazhuang Camps Shijiazhuang 050031 Hebei Peoples R China

To explore the mechanism of miR-202-5p targeting the expression of PIK3CA and mediating the activation of PI3K/Akt/mTOR signaling pathway on the proliferation, invasion, and epithelial-mesenchymal transition (EMT) of cervical cancer. The objects of study were 105 cases of cervical cancer and their corresponding normal tissues. qRT-PCR was used to detect the expression of miR-202-5p and PIK3CA in adjacent normal tissue and cervical cancer tissue. Dual luciferase reporter assay was used to verify the targeting relationship between miR-202-5p and PIK3CA gene. Human cervical cancer cell lines HPV-16E6, SiHa, HeLa, and CaSki were purchased for our cell experiments. The expression levels of PIK3CA in the cells were detected by qRT-PCR. The cell line with higher expression levels was selected to complete the follow-up experiment. The cultured cells were transfected and divided into the miR-202-5p mimic NC group, miR-202-5p mimic group, miR-202-5p inhibitor NC group, miR-202-5p inhibitor group, siRNA-PIK3CA NC group, siRNA-PIK3CA group, miR-202-5p inhibitor NC + siRNA-PIK3CA NC group, miR-202-5p inhibitor + siRNA-PIK3CA NC group, and miR-202-5p inhibitor + siRNA-PIK3CA group. QRT-PCR was used to detect the expression of miR-202-5p. Western blot and qRT-PCR were applied to detect the mRNA and protein expression levels of related pathway proteins (PIK3CA, PI3K, PTEN, p-Akt1, and p-mTOR) and epithelial-mesenchymal transition-related factors (N-cadherin, E-cadherin, and vimentin). Cell proliferation was detected by plate colony formation assay. Transwell assay was used to detect the invasion ability of each group. When compared with the adjacent tissues, PIK3CA mRNA expression level was significantly increased and miR-202-5p expression level was significantly decreased in cervical cancer tissues (all P < 0.05). PIK3CA was a target gene of miR-202-5p. The mRNA expression level of PIK3CA in SiHa cervical cancer cells was significantly higher than that in CaSki, HeLa, and HPV-16E6

关键词： miR-202-5p PIK3CA gene PI3K Akt mTOR signaling pathway Cervical cancer Epithelial-mesenchymal transition

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Supplementation of Alhagi honey polysaccharides contributes to the improvement of the intestinal immunity regulating the structure of intestinal flora in mice

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FOOD & FUNCTION 2021年第20期12卷 9693-9707页

作者： Cai, Gaofeng Wusiman, Adelijiang Gu, Pengfei Mao, Ningning xu, shuwen Zhu, Tianyu He, Jin Liu, Zhenguang Wang, Deyun Nanjing Agr Univ Coll Vet Med Inst Tradit Chinese Vet Med Nanjing 210095 Peoples R China Nanjing Agr Univ Coll Vet Med MOE Joint Int Res Lab Anim Hlth & Food Safety Nanjing 210095 Peoples R China Xinjiang Agr Univ Coll Vet Med Urumqi 830000 Peoples R China

Alhagi honey polysaccharides (AH), a main active component of Alhagi honey, are known to possess excellent pharmacological activities and have been widely used as dietary supplements in traditional Chinese medicine for thousands of years. This study is aimed to investigate the heath effect of AH on murine intestinal mucosal immune function and composition of the gut microbiome. ICR mice received daily intragastric administration of AH (three dosages, 200 mg kg(-1), 400 mg kg(-1), and 800 mg kg(-1)) or saline for 7 consecutive days. Results indicated an improvement in the intestinal barrier function through increases in secretory immunoglobulin A (sIgA) and beta-defensins. Simultaneously, AH also significantly stimulated IL-2, IL-4, IL-6, IL-10, IL-17, IFN-gamma, and TNF-alpha cytokine secretion as compared to the control samples. Moreover, hematoxylin and eosin staining showed that AH enhanced the number of intraepithelial lymphocytes (IELs) in the small intestine. An obvious increase in the ratio of IgA(+) cells of AH-treatment samples in the lamina propria was also detected by immunohistochemical staining. In addition, the CD3(+), CD4(+) and CD8(+) T-cell ratio in mesenteric lymph nodes and Peyer's patches in the AH-treatment was significantly higher than that in the control group. Furthermore, 16S rDNA gene sequencing was used to monitor the dynamic changes in the gut microbiota. The result revealed that AH significantly increased the indexes of Shannon and obviously decreased the indexes of Simpson, suggesting the enhancement of the diversity and richness of the intestinal microbiome. Moreover, AH modulated the gut microbiome via increasing the abundance of probiotics and decreasing the levels of pathogenic bacteria. In summary, these results indicated that AH could be used as a prebiotic to enhance murine intestinal mucosal immunity and to modulate the gut microbiome.

关键词： Polysaccharides

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一种基于虚拟仪器技术的视频分析仪校准装置

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计量学报 2024年第10期45卷 1562-1569页

作者：刘雷徐书文韩正涛陈鹏韩东中国电子科技集团公司第三研究所北京100015

针对视频分析仪校准中主要标准器停产以及校准过程繁琐的问题,基于虚拟仪器技术,在LabVIEW开发环境下,利用M4i.6622-x8任意波形发生卡作为信号发生模块,开发了一种视频分析仪校准装置。实现了视频分析仪基本参数和失真参数的校准,给出... 详细信息

针对视频分析仪校准中主要标准器停产以及校准过程繁琐的问题,基于虚拟仪器技术,在LabVIEW开发环境下,利用M4i.6622-x8任意波形发生卡作为信号发生模块,开发了一种视频分析仪校准装置。实现了视频分析仪基本参数和失真参数的校准,给出了亮度电平、色度电平、色度相位等视频基本参数和行倾斜、k_(p)系数(2T脉冲k系数)、色度-亮度增益差、色度-亮度时延差、亮度非线性失真等视频失真参数的校准信号产生过程。经过实验,技术指标可达到如下:亮度电平为±0.2%,色度电平为±0.2%,色度相位为±0.1°,行倾斜为±0.1%,k_(p)系数为±0.1%,色度-亮度增益差为±0.2%,色度-亮度时延差为±3 ns,亮度非线性失真为±0.2%;优于TG2000可编程视频信号发生器,满足视频分析仪校准要求。

关键词：视频参量计量虚拟仪器视频分析仪校准装置任意波形发生卡

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An approach for improving firefighting ability of forest road network

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SCANDINAVIAN JOURNAL OF FOREST RESEARCH 2020年第8期35卷 547-561页

作者： Zhang, Fuquan Dong, Yuzhen xu, shuwen Yang, xubing Lin, Haifeng Nanjing Forestry Univ Coll Informat Sci & Technol Nanjing Peoples R China Xidian Univ Natl Lab Radar Signal Proc Xian Peoples R China

Forest road network plays a key role in shortening the response time of firefighting activities. Therefore, evaluation and improvement of the ability of firefighting of the forest roads are essential. The widely used travel time criterion evaluation showed that firefighters can reach the areas of fires by walking and carrying portable fire equipment. However, the firefighting capability provided by this method is very limited. It is difficult to ensure that the fires can be controlled. This study proposed a new firefighting distance criterion (FFDC) to evaluate the actual firefighting coverage of the road network. Then, we proposed an approach that aims at mapping the optimal forest road network based on the FFDC. The results showed that the new planned forest road network increases the coverage of the study area from 37.2% to 57.95%. Moreover, to evaluate the influence on the forest environment, we further assessed the newly planned forest road network by using intensity evaluation criteria and absorption evaluation criteria, which are based on a multi-criteria evaluation (MCE). The intensity evaluation was 88.05%, and the absorption evaluation was 68.22%. The forest absorption capacity in the study area was good, and the road network had little impact on the environment.

关键词： Forest fire road network planning geographic information system multi-criteria evaluation

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Dynamic track model of miscible CO2 geological utilizations with complex microscopic pore-throat structures

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FUEL 2022年 322卷 1页

作者： Tian, Leng Zhang, Kaiqiang Wang, Hengli Liu, Zongke Huo, Minghui xu, shuwen China Univ Petr State Key Lab Petr Resources & Prospecting Beijing 102249 Peoples R China China Univ Petr Coll Petr Engn Beijing 102249 Peoples R China Changqing Oilfield Petrochina Res Inst Explorat & Dev Xian 710018 Peoples R China CNPC Logging Co Ltd North China Branch Renqiu 062550 Peoples R China Peking Univ Inst Energy Beijing 100871 Peoples R China

Monitoring field-scale CO2 geological utilizations is of paramount importance but challenging due to the complexities in microscopic heterogeneity. In this paper, complex geological characterizations and fluid properties are specifically analysed and a prediction model is developed, which is capable to track the dynamic behaviour of miscible CO2 multiphase flow in microscopically-heterogeneous porous media. More specifically, first, porethroat sizes and distributions were characterised from the constant-rate mercury injection and the CO2displacement seepage resistance was evaluated from a capillary bundle model. The differences of seepage resistance caused from the throat changing and coupling diffusion-dissolution effects and viscosity-resistance reductions were specifically studied in the process of continuous miscible CO2 displacement. Accordingly, a comprehensive mathematical model was developed with the time-node analysis method and validated through comparison with the experimental results. The leading edge of CO2 displacement as well as the timing of gas breakthrough and displacement completion are determined to be different with varying throat sizes. It is further found that the gas breakthrough time and the time required to complete the displacement are reduced with increasing throat size and their differences also decrease. Moreover, the interval area of injection and production wells could be characterised as pure CO2, diffusion and pure oil zones, whose positions could be dynamically tracked from the recovery performance. The calculated oil recovery and gas-oil ratio from the developed model share good agreement with experimental results, with deviations of 2.2 and 0.7%. Such the validated mathematical model is then applied to successfully predict the dynamic performance of an actual reservoir (H3).

关键词： Geological CO 2 utilization Dynamic track mathematical model Miscible state Complex microscopic structures Theory with practice

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Neuroprotective effects of Lycium barbarum polysaccharide on light-induced oxidative stress and mitochondrial damage via the Nrf2/HO-1 pathway in mouse hippocampal neurons

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INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES 2023年第1期251卷 126315页

作者： Yang, Yang Yu, Lin Zhu, Tianyu xu, shuwen He, Jin Mao, Ningning Liu, Zhenguang Wang, Deyun Nanjing Agr Univ Inst Tradit Chinese Vet Med Coll Vet Med Nanjing 210095 Peoples R China Nanjing Agr Univ Inst Immunol MOE Joint Int Res Lab Anim Hlth & Food Safety Nanjing 210095 Peoples R China Nanjing Agr Univ Coll Vet Med Nanjing 210095 Peoples R China

Light at night (LAN) induced cognitive impairment associated with oxidative stress in mice has been reported. Lycium barbarum polysaccharide (LBP) exhibits anti-tumor, anti-oxidant and neuroprotective effects, yet the neuroprotective effect on light-induced neuron damage still unclear. Here, mice exposed to LAN displayed cognitive impairment and depressive like behavior, which was reversed by LBP treatment. Meanwhile, LBP alleviated light-induced higher apoptosis and mitochondrial damage in HT-22 cells. Also, LBP prevented the decreased of mitochondrial membrane permeabilization (MMP) level in light-treated cells. Additionally, LBP demonstrated its antioxidant potential by reducing ROS production and malondialdehyde (MDA) level, while simultaneously enhancing the levels of superoxide dismutase (SOD) and glutathione peroxidases (GSH-Px) in both light-treated mice and HT-22 cells. Furthermore, the mRNA and protein expression of Nrf2 (NF-E2-related factor 2), heme oxygenease-1 (HO-1), and NAD(P)H quinone oxidoreductase (NQO1) were decreased in both light-treated mice and cells. Additionally, LBP treatment reversed light-induced the inhibition of Nrf2/HO-1 signaling pathway in both mice and cells. Moreover, Nrf2 antagonist ML385 significantly eliminated the neuroprotection of LBP on cell apoptosis, oxidative stress and mitochondrial damage in light-treated cells. These results indicate that LBP can rescue light-induced neurotoxicity in mice and HT-22 cells by activating the Nrf2/ HO-1 signaling pathway.

关键词： Light at night Lycium barbarum polysaccharide Nrf2/HO-1

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Wald- and Rao-Based Detection for Maritime Radar Targets in Sea Clutter With Lognormal Texture

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IEEE TRANSACTIONS ON GEOSCIENCE AND REMOTE SENSING 2022年 60卷 1页

作者： xue, Jian Ma, Manshan Liu, Jun Pan, Meiyan xu, shuwen Fang, Jie Xian Univ Posts & Telecommunicat Sch Commun & Informat Engn Xian 710121 Peoples R China Univ Sci & Technol China Dept Elect Engn & Informat Sci Hefei 230027 Peoples R China Xian Elect Engn Res Inst Xian 710100 Peoples R China Xidian Univ Natl Lab Radar Signal Proc Xian 710071 Peoples R China

Non-Gaussian sea clutter causes conventional detectors designed in Gaussian clutter to suffer detection performance degradation, and some nuisance parameters cause the uniformly most powerful test to be unavailable. To improve the detection performance of maritime radar targets, we investigate the design of adaptive detectors in correlated non-Gaussian sea clutter by using suboptimal tests. The non-Gaussian sea clutter is modeled as a product of lognormal-distributed texture and complex Gaussian speckle. Two adaptive radar target detectors are developed by using the suboptimal two-step Wald and Rao tests. Specifically, a nonadaptive detector is derived by the Wald or Rao test when the clutter texture and speckle covariance matrix are assumed to be known in the first step;then the clutter parameters known in the first step are estimated, and the true parameters of the detector obtained in the first step are replaced with the estimated values. Theoretical proof and experimental verification indicate that the two proposed detectors have the constant false alarm property with regard to the clutter speckle covariance matrix and the clutter average power. Numerical results on simulated and measured radar data show that the proposed Rao-based detector outperforms its competitors and has stronger robustness to the signal mismatch compared to the proposed Wald-based detector.

关键词： Clutter Radar Detectors Radar detection Radar clutter Speckle Covariance matrices Lognormal texture radar targets Rao test sea clutter Wald test

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