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16th International Conference on Digital Image Processing, ICDIP 2024

作者： Yang, Tingting Jia, shuwen yu, Ying Zhou, Xue School of Information and Intelligence Engineering University of Sanya Sanya572022 China

ISBN: (数字)9781510682917

ISBN: (纸本)9781510682900

The presence of moving objects in real-world scenarios can lead to mismatches in visual odometry feature points, thereby affecting the accuracy of positioning and mapping by the SLAM system and reducing its robustness in practical applications. This paper introduces a visual SLAM algorithm that leverages the ORB-SLAM3 framework and deep learning techniques. Enhancements to the SLAM system’s tracking thread enable identifying and removing dynamic feature points, thus increasing its adaptability to dynamic environments. Concurrently, YOLOv8s, known for its minimal depth and feature map width in the YOLOv5 series, is selected as the object detection network, with VanillaNet, a lightweight network, replacing its backbone network. This combination effectively determines the mobility of objects within the environment. Consequently, we propose an enhanced algorithm based on YOLOv8s capable of performing both object detection and semantic segmentation to eliminate dynamic feature points precisely. Ultimately, the algorithm’s accuracy and real-time performance were assessed using indoor dynamic scene data from the TUM RGB datasets. In comparison to models lacking any strategic approach, test results on the TUM datasets reveal that the experimental outcomes are more favorable in dynamic environments. © 2024 SPIE.

关键词： Semantic Segmentation

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Electrochemical Aptamer-Based Sensors with Tunable Detection Range

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ANALYTICAL CHEMISTRY 2023年第1期95卷 420-432页

作者： Pan, Jing Xu, Wenxia Li, Wanlu Chen, shuwen Dai, yu yu, Shanwu Zhou, Qitao Xia, Fan China Univ Geosci Fac Mat Sci & Chem State Key Lab Biogeol & Environm Geol Wuhan 430074 Peoples R China

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AIMP2 restricts EV71 replication by recruiting SMURF2 to promote the degradation of 3D polymerase

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Virologica Sinica 2024年第4期39卷 632-644页

作者： Junrui Ren Lei yu Qiuhan Zhang Pengyu Ren yumeng Cai Xueyun Wang Ke Lan shuwen Wu State Key Laboratory of Virology College of Life SciencesWuhan UniversityWuhan430072China Medical Research Institute Wuhan UniversityWuhan430072China Taikang Center for Life and Medical Sciences Wuhan UniversityWuhan430072China

Hand,foot and mouth disease(HFMD),mainly caused by enterovirus 71(EV71),has frequently occurred in the Asia-Pacific region,posing a significant threat to the health of infants and young ***,research on the infection mechanism and pathogenicity of enteroviruses is increasingly becoming *** 3D polymerase,as the most critical RNA-dependent RNA polymerase(RdRp)for EV71 replication,is widely targeted to inhibit EV71 *** this study,we identified a novel host protein,AIMP2,capable of binding to 3D polymerase and inhibiting EV71 *** investigations revealed that AIMP2 recruits the E3 ligase SMURF2,which mediates the polyubiquitination and degradation of 3D ***,the antiviral effect of AIMP2 extended to the CVA16 and CVB1 *** research has uncovered the dynamic regulatory function of AIMP2 during EV71 infection,revealing a novel antiviral mechanism and providing new insights for the development of antienteroviral therapeutic strategies.

关键词： AIMP2 Enterovirus 71(EV71) 3D polymerase E3 ligase SMURF2 Ubiquitination

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Phenological control of vegetation biophysical feedbacks to the regional climate

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Geography and Sustainability 2025年第1期6卷 223-237页

作者： Lingxue yu Ye Liu Fengqin Yan Lijie Lu Xuan Li shuwen Zhang Jiuchun Yang State Key Laboratory of Black Soils Conservation and Utilization Northeast Institute of Geography and AgroecologyChinese Academy of SciencesChangchun 130102China Pacific Northwest National Laboratory RichlandWA 99352USA State Key Laboratory of Resources and Environmental Information System Institute of Geographical Sciences and Natural Resources ResearchChinese Academy of SciencesBeijing 100101China

Phenology shifts influence regional climate by altering energy,and water fluxes through biophysical ***,a quantitative understanding of the phenological control on vegetation’s biophysical feedbacks to re gional climate remains *** long-term remote sensing observations and Weather Research and Fore casting(WRF)model simulations,we investigated vegetation phenology changes from 2003 to 2020 and quan tified their biophysical controls on the regional climate in Northeast *** findings elucidated that earlier green-up contributed to a prolonged growing season in forests,while advanced green-up and delayed dormancy extended the growing season in *** prolonged presence and increased maximum green cover in tensified climate-vegetation interactions,resulting in more significant surface cooling in croplands compared to *** cooling from forest phenology changes was prominent during May’s green-up(-0.53±0.07°C),while crop phenology changes induced cooling throughout the growing season,particularly in June(-0.47±0.15°C),July(-0.48±0.11°C),and September(-0.28±0.09°C).Furthermore,we unraveled the contributions of different biophysical pathways to temperature feedback using a two-resistance attribution model,with aero dynamic resistance emerging as the dominant ***,our findings underscored that the land surface temperature(LST)sensitivity,exhibited substantially higher values in croplands rather than temperate *** strong sensitivities,coupled with the projected continuation of phenology shifts,portend further growing season cooling in *** findings contribute to a more comprehensive understanding of the intricate feedback mechanisms between vegetation phenology and surface temperature,emphasizing the significance of vegetation phenology dynamics in shaping regional climate pattern and seasonality.

关键词： Phenology shifts Biophysical feedback Land-atmosphere interactions Regional climate simulation

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The impact of population agglomeration on economic resilience: Evidence from 280 cities in China

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INTERNATIONAL REVIEW OF ECONOMICS & FINANCE 2024年 94卷

作者： Liu, shuwen Li, Youli Shen, Zhihan yu, Jinyi Xu, Zhaoyi Hunan Univ Technol & Business Coll Accounting Changsha 410205 Peoples R China Capital Univ Econ & Business Int Sch Econ & Management Beijing 100070 Peoples R China Renmin Univ China Sch Arts Sch Econ Beijing 100872 Peoples R China Tsinghua Univ Sch Econ & Management Beijing 100062 Peoples R China

This paper uses data from 280 cities in the period from 2008 to 2021 to investigate the impact of population agglomeration on economic resilience. The empirical results reveal that population agglomeration significantly improves economic resilience. Moreover, these findings demonstrate the robustness including a new additional sample, alternative measures for economic resilience, the inclusion of supplementary control variables, and the application of the instrumental variable methodology. Furthermore, population agglomeration improves economic resilience through stimulating consumer demand and promoting technological innovation. Analyses also show that, compared to cities with high levels of informatization, industrialization and marketization, population agglomeration is more likely to improve economic resilience. Overall, this study provides new insights into population agglomeration and economic resilience.

关键词： Population agglomeration Economic resilience Consumer effective demand Technological innovation

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Eight EDA mutations in Chinese patients with tooth agenesis and genotype-phenotype analysis

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ORAL DISEASES 2024年第7期30卷 4598-4607页

作者： yu, Kang Sheng, Yihan Wang, Feng Yang, shuwen Wan, Futang Lei, Ming Wu, Yiqun Shanghai Jiao Tong Univ Natl Clin Res Ctr Stomatol Peoples Hosp Affiliated 9 Shanghai Key Lab StomatolSch MedDept Dent Ctr 2 Shanghai Peoples R China Shanghai Jiao Tong Univ Peoples Hosp 9 Sch Med Shanghai Peoples R China Shanghai Inst Precis Med 115 Jinzun Rd Shanghai 200125 Peoples R China

ObjectiveTooth agenesis is a common craniofacial malformation, which is often associated with gene mutations. The purpose of this research was to investigate and uncover ectodysplasin A (EDA) gene variants in eight Chinese families affected with tooth agenesis. MethodsGenomic DNA was extracted from tooth agenesis families and sequenced using whole-exome sequencing. The expression of ectodysplasin A1 (EDA1) protein was studied by western blot, binding activity with receptor was tested by pull-down and the NF-kappa B transcriptional activity was analyzed by Dual luciferase assay. ResultsEight EDA missense variants were discovered, of which two (c.T812C, c.A1073G) were novel. The bioinformatics analysis indicated that these variants might be pathogenic. The tertiary structure analysis revealed that these eight variants could cause structural damage to EDA proteins. In vitro functional studies demonstrated that the variants greatly affect protein stability or impair the EDA-EDAR interaction;thereby significantly affecting the downstream NF-kappa b transcriptional activity. In addition, we summarized the genotype-phenotype correlation caused by EDA variants and found that EDA mutations leading to NSTA are mostly missense mutations located in the TNF domain. ConclusionOur results broaden the variant spectrum of the EDA gene associated with tooth agenesis and provide valuable information for future genetic counseling.

关键词： EDA gene mutation genotype-phenotype hypohidrotic ectodermal dysplasia tooth agenesis

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The use of heat-treated whey protein isolate as a natural emulsifier in fat-filled whey powder with a pre-emulsification process

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JOURNAL OF THE SCIENCE OF FOOD AND AGRICULTURE 2025年第5期105卷 3146-3150页

作者： Li, Hongjuan Li, Ke Zhang, Leilei Wu, Zhengyan yu, Hongmei Li, Hongbo Lv, Jiaping Zhang, shuwen yu, Jinghua Tianjin Univ Sci & Technol Coll Food Sci & Engn State Key Lab Food Nutr & Safety Minist Educ 2913 AveTEDA Tianjin 300457 Peoples R China Chinese Acad Agr Sci Inst Food Sci & Technol Beijing Peoples R China

BACKGROUNDFat-filled whey powder is a type of whey powder that has been developed in recent years and is widely applied in the dry processing of infant formula milk powder. The addition of sodium caseinate, dextrin, or modified starch as emulsifiers can also improve the stability of fat-filled whey powders. However, regulations forbid the use of these substances as raw materials in powdered infant formulas. The development of new natural emulsifiers is therefore *** pre-emulsification process (P-EP) with heat-treated whey protein (HWP) increased the solubility of fat-filled whey powders, reduced the Turbiscan stability index value, and reduced surface fat content. Microstructural analysis showed that the fat-filled whey powder in the experimental group (<= 35 wt% fat in dry matter) exhibited a more uniform particle distribution in comparison with a control *** P-EP with HWP as a natural emulsifier can improve the stability and emulsifying effect in fat-filled whey powders. The use of P-EP with HWP was a promising method for producing fat-filled whey powder without artificial additives, relying solely on milk-derived ingredients for a clean label. (c) 2024 Society of Chemical Industry.

关键词： fat-filled whey powder whey protein natural emulsifier pre-emulsification

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Hypophosphatemia is an independent risk factor for AKI among hospitalized patients with COVID-19 infection

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RENAL FAILURE 2021年第1期43卷 1329-1337页

作者： Chen, Zijin Gao, Chenni yu, Haijin Lu, Lin Liu, Jialin Chen, Wei Xiang, Xiaogang Hussain, Hafiz Muhammad Jafar Lee, Benjamin J. Li, Chuanlei Wei, Wenjie Huang, yuhan Li, Xiang Fang, Zhengying yu, shuwen Weng, Qinjie Ouyang, Yan Hu, Xiaofan Tong, Jun Liu, Jian Lin, Li Liu, Mingyu Xu, Xiaoman Liu, Dan Song, yuan Lv, Xifeng Zha, Yixin Ye, Zhiyin Jiang, Tingting Jia, Jieshuang Chen, Xiaonong Bi, yufang Xue, Jun Chen, Nan Hu, Weiguo He, Cijiang John Wang, Huiming Liu, Jun Xie, Jingyuan Shanghai Jiao Tong Univ Inst Nephrol Sch Med Ruijin HospDept Nephrol 197 Ruijin Er Rd Shanghai 200025 Peoples R China Fudan Univ North Huashan Hosp Dept Nephrol Shanghai Peoples R China Shanghai Jiao Tong Univ Sch Med Ruijin Hosp Dept Crit Care Med Shanghai Peoples R China Shanghai Jiao Tong Univ Inst Resp Dis Sch Med Ruijin HospDept Pulm & Critical Care Med Shanghai Peoples R China Shanghai Jiao Tong Univ Sch Med Ruijin Hosp Dept Infect Dis Shanghai Peoples R China Houston Kidney Consultants Houston TX USA Houston Methodist Inst Acad Med Houston TX USA Shanghai Jiao Tong Univ Shanghai Gen Hosp Dept Nephrol 85 Wujin Rd Shanghai 200080 Peoples R China Wuhan Ninth Hosp Wuhan Peoples R China Wuhan Ninth Hosp Renal Dept Wuhan Hubei Peoples R China Wuhan Univ Renmin Hosp Radiol Dept Wuhan Hubei Peoples R China Wuhan Univ Renmin Hosp Renal Dept Jiefang Rd 238 Wuhan 430060 Hubei Peoples R China Shanghai Jiao Tong Univ Shanghai Gen Hosp Clin Res Ctr Shanghai Peoples R China Shanghai Jiao Tong Univ Sch Med Ruijin Hosp Dept Endocrinol & Metab Dis Shanghai Peoples R China Fudan Univ Huashan Hosp Dept Nephrol Shanghai Peoples R China Shanghai Jiao Tong Univ Ruijin Hosp Sch Med Dept Surg Shanghai Peoples R China Mt Sinai Sch Med Div Nephrol New York NY USA

Background This study sought to investigate incidence and risk factors for acute kidney injury (AKI) in hospitalized COVID-19. Methods In this retrospective study, we enrolled 823 COVID-19 patients with at least two evaluations of renal function during hospitalization from four hospitals in Wuhan, China between February 2020 and April 2020. Clinical and laboratory parameters at the time of admission and follow-up data were recorded. Systemic renal tubular dysfunction was evaluated via 24-h urine collections in a subgroup of 55 patients. Results In total, 823 patients were enrolled (50.5% male) with a mean age of 60.9 +/- 14.9 years. AKI occurred in 38 (40.9%) ICU cases but only 6 (0.8%) non-ICU cases. Using forward stepwise Cox regression analysis, we found eight independent risk factors for AKI including decreased platelet level, lower albumin level, lower phosphorus level, higher level of lactate dehydrogenase (LDH), procalcitonin, C-reactive protein (CRP), urea, and prothrombin time (PT) on admission. For every 0.1 mmol/L decreases in serum phosphorus level, patients had a 1.34-fold (95% CI 1.14-1.58) increased risk of AKI. Patients with hypophosphatemia were likely to be older and with lower lymphocyte count, lower serum albumin level, lower uric acid, higher LDH, and higher CRP. Furthermore, serum phosphorus level was positively correlated with phosphate tubular maximum per volume of filtrate (TmP/GFR) (Pearson r = 0.66, p < .001) in subgroup analysis, indicating renal phosphate loss via proximal renal tubular dysfunction. Conclusion The AKI incidence was very low in non-ICU patients as compared to ICU patients. Hypophosphatemia is an independent risk factor for AKI in patients hospitalized for COVID-19 infection.

关键词： COVID-19 proximal tubule acute kidney injury risk factors hypophosphate

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Simulation and Experimental Investigation of Fe-based Alloy Powder Production by Gas Atomization

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JOURNAL OF MATERIALS ENGINEERING AND PERFORMANCE 2024年 1-16页

作者： Guan, shuwen Gan, Bin Liu, Shichang Chen, Fucai Tan, Bo Liu, Zhen Xiao, Guanfei yu, Bo CAM Shenyang Res Inst Foundry Co Ltd Natl Key Lab Adv Casting Technol Shenyang 110022 Peoples R China Nucl Power Inst China Sci & Technol Reactor Syst Design Technol Lab Chengdu 610213 Peoples R China

The gas atomization is commonly utilized to produce metal powder in additive manufacturing. Based on experimental data, this paper used computational fluid dynamics to simulate the flow field and analyze the gas-melt two-phase mechanism in two-stage atomization. The study investigated the impact of atomization parameters and nozzle structure on aspiration pressure, gas flow field, and particle size distribution. The results indicated that a delivery tube protrusion length of 3 mm achieves a stable atomization process. Furthermore, the particle size of the powder decreased initially and then increased with an increase in injection angle. The VOF (Volume of Fluid) model and DPM (Discrete Phase Model) could effectively simulate the gas atomization process, with the simulated particle size distribution closely aligning with the experimental results. The experimental Fe-based alloy powder exhibited good sphericity with minimal satellites, making it suitable for laser additive manufacturing with metallic materials.

关键词： atomization parameters gas atomization metal powder nozzle structure numerical simulation

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Effects of different processed tomatoes on carotenoid release and microbiota composition during in vitro gastrointestinal digestion and colonic fermentation

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FOOD & FUNCTION 2023年第22期14卷 10177-10187页

作者： Wu, Xinyi Zhu, Changan Zhang, Min Wang, shuwen yu, Jingquan Tian, Jinhu Hu, Zhangjian Zhejiang Univ Dept Hort Hangzhou 310058 Peoples R China Zhejiang Univ Coll Biosyst Engn & Food Sci Hangzhou 310058 Peoples R China Zhejiang Univ Hainan Inst Sanya 572000 Peoples R China

Carotenoids in tomatoes confer significant health benefits to humans but with the disadvantage of the carotenoids from raw tomatoes not being easily absorbed for utilization. Thus, this study aimed to investigate the effects of different cooking processes on carotenoid release and human gut microbiota composition during in vitro simulated gastrointestinal digestion of tomatoes. The results showed that stir-frying significantly increased the release of lycopene and beta-carotene during gastrointestinal digestion, with boiling being the second most effective treatment. The boiling-treated tomatoes enhanced the carotenoid release during in vitro fermentation. Gut microbiota analysis revealed that the digestion of the raw and boiled tomatoes promoted the growth of potentially beneficial microbiota while reducing the ratio of Firmicutes/Bacteroides, which potentially helps prevent obesity. Boiling treatment significantly reduced the growth of Peptostreptococcus and was negatively correlated with carotenoid release. Overall, the boiling-treated tomatoes were more effective than the raw or stir-fried tomatoes in terms of both colon health benefits and carotenoid release.

关键词： Carotenoids

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