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13th International Conference on Computer Engineering and Networks, CENet 2023

作者： Shang, Ronghao Zhang, Yide Zhou, Tonghui Cheng, Tai Liang, Kun Zhang, wuwen Wang, Ting Shi, Zhongwei Xu, Yuan School of Electrical Engineering University of Jinan Shandong Jinan250022 China

ISBN: (纸本)9789819992386

Localization accuracy is an important index for evaluating multi-sensor integrated system. For ensuring the high precision, usually more accuracy sensor is adopted for reducing the measurement error or better localization algorithms are used. This paper proposes an adaptive one-step prediction enhanced algorithm that combines kalman filter (KF) algorithm for INS/Computer Vision integrated localization system, to address the issue of some data in the inertial navigation system (INS) being unusable for data fusion. The process can be realized by determining whether one-step prediction is needed by the fast or slow motion of the robot. Based on that, the optimal estimation of the system state can be achieved by computer programming. Analysis of computer simulation experimental is done by comparing the proposed algorithm with INS/Computer Vision integrated KF and one-step prediction enhanced KF, the positioning accuracy can be enhanced and the positioning error can be minimized. © The Author(s), under exclusive license to Springer Nature Singapore Pte Ltd 2024.

关键词： Inertial navigation systems

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The role of exosomal lncRNAs in cancer biology and clinical management

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EXPERIMENTAL AND MOLECULAR MEDICINE 2021年第11期53卷 1669-1673页

作者： Zhang, wuwen Wang, Qinshi Yang, Yi Zhou, Siyuan Zhang, Ping Feng, Tongbao Nanjing Med Univ Affiliated Changzhou Peoples Hosp 2 Dept Clin Lab Changzhou Peoples R China

Cancer: eavesdropping on communicating cancer cells Cancer cells routinely release tiny membrane vesicles laden with RNAs that help promote tumor progression, but which could also offer useful biomarkers for diagnosis and reveal new drug targets. Many cells secrete such vesicles, known as exosomes, as a mode of intercellular communication. Researchers led by Tongbao Feng at Nanjing Medical University, Changzhou, China, have reviewed the evidence linking exosome-borne RNAs to tumor cell function. The authors focus on a class of molecules known as 'long noncoding RNAs' (lncRNAs), and show that exosomal lncRNAs are relayed as messages between tumor cells, promoting proliferation, metastatic spread, and acquisition of drug resistance. These RNAs can therefore also offer a useful window into the progress of disease and interventions that block such exosomally transmitted messages, and could potentially inhibit malignant growth and spread. Exosomes play a vital role in cell-cell communication within the cancer microenvironment. Exosomal long noncoding RNAs (lncRNAs) are important regulators in cancer development and are involved in multiple processes, including cancer cell proliferation, angiogenesis, metastasis, drug resistance, and immunomodulation. Changes in the levels of exosomal lncRNAs often appear with the occurrence and development of cancer. Therefore, exosomal lncRNAs can be used as biomarkers for cancer diagnosis and prognosis. Exosomal lncRNAs can also indicate the treatment response of patients receiving chemotherapy. Moreover, exosomal lncRNAs are potential therapeutic targets for cancer treatment. In this review, we summarize the role of exosomal lncRNAs in cancer biology as well as in clinical management. A more comprehensive and in-depth understanding of the role of exosomal lncRNAs in cancer may help us better understand the mechanism of cancer development and clinically manage cancer patients.

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Functional analysis of ascP in Aeromonas veronii TH0426 reveals a key role in the regulation of virulence

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JOURNAL OF MICROBIOLOGY 2022年第12期60卷 1153-1161页

作者： Guan, Yongchao Zhang, Meng Wang, Yingda Liu, Zhongzhuo Zhao, Zelin Wang, Hong An, Dingjie Qian, Aidong Kang, Yuanhuan Sun, wuwen Shan, Xiaofeng Jilin Agr Univ Coll Vet Med Coll Anim Sci & Technol Changchun 130118 Peoples R China

Aeromonas veronii is a pathogen which can induce diseases in humans, animals and aquatic organisms, but its pathogenic mechanism and virulence factors are still elusive. In this study, we successfully constructed a mutant strain (Delta ascP) by homologous recombination. The results showed that the deletion of the ascP gene significantly down-regulated the expression of associated effector proteins in A. veronii compared to its wild type. The adhesive and invasive abilities of Delta ascP to EPC cells were 0.82-fold lower in contrast to the wild strain. The toxicity of Delta ascP to cells was decreased by about 2.91-fold (1 h) and 1.74-fold (2 h). Furthermore, the LD50 of the mutant strain of crucian carp was reduced by 19.94-fold, and the virulence was considerably attenuated. In contrast to the wild strain, the Delta ascP content in the liver and spleen was considerably lower. The titers of serum cytokines (IL-8, TNF-alpha, and IL-1 beta) in crucian carp after the infection of the Delta ascP strain were considerably lower in contrast to the wild strain. Hence, the ascP gene is essential for the etiopathogenesis of A. veronii TH0426.

关键词： Aeromonas veronii ascP gene T3SS virulence

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A method for optimizing the precision of weighted fourier integral transformation algorithm 3

A method for optimizing the precision of weighted fourier in...

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3rd International Conference on Defence Technology, ICDT 2022

作者： Jianhang, Sun Yang, Liu Chunran, Sun wuwen, Lai Shi, Pan Jun, Zhou Ziheng, Cheng Weidong, Hu System Integration Department China North Industries Crop. Beijing100053 China School of Integrated Circuits and Electronics Beijing Institute of Technology Beijing100081 China

RCS refers to the radar cross section, which is an important index to reflect the electromagnetic scattering characteristics of the object. RCS measurement is the only method to obtain the real RCS of objects. Since test range often cannot reach the far-field condition for large size object, the near-field-to-far-field transformation(NFFFT) technology is significant in the RCS measurement. The core of NFFFT are different algorithms. Among them, the weighted fourier integral transformation is a universal algorithm, but the data in the aspect angle is segmented in the process, which leads to the discontinuity of the transformation results at the splicing point. This paper introduces a method to optimize the precision of weighted fourier integral transformation algorithm, which can fully suppress the discontinuity of transform results and improve the precision of weighted fourier integral transformation algorithm under the paraxial constraint conditions. Finally, the result of simulation demonstrates the precision and efficiency of this method. © Published under licence by IOP Publishing Ltd.

关键词： Radar cross section

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Highly Selective Dual-Atom Pd Heterogeneous Catalyst Prepared by Size-Selected Cluster Beam

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ACS CATALYSIS 2024年第17期14卷 12982-12990页

作者： Zhu, wuwen Xu, Ning Lin, Xingen Hu, Shengyong Tang, Sichen Shah, Syed Adil Zhao, Zixiang Zhang, Yongxin Lu, Siqi Lu, Ximing Wan, Jianguo Xu, Wenwu Zhou, Huang Hu, Kuojuei Han, Zhong-Kang Wu, Yuen Song, Fengqi Nanjing Univ Collaborat Innovat Ctr Adv Microstruct Sch Phys Natl Lab Solid State Microstruct Nanjing 210093 Peoples R China Nanjing Univ Inst Atom Mfg Suzhou Campus Nanjing 215163 Peoples R China Zhejiang Univ Sch Mat Sci & Engn Hangzhou 310027 Peoples R China Ningbo Univ Sch Phys Sci & Technol Dept Phys Ningbo 315211 Peoples R China Univ Sci & Technol China Sch Chem & Mat Sci Hefei 230026 Peoples R China

Atomic dispersed heterogeneous catalysts have emerged as a prominent research focus in catalysis due to their exceptional atom utilization, robust activity, and remarkable selectivity. However, the design and synthesis of catalysts with a precisely defined atomic number and exceptional dispersion still pose significant challenges. In this study, we employed a magnetron sputtering cluster source equipped with a mass selector to selectively fabricate single-atom, dual-atom, and clusters with precise atomic numbers catalysts supported on mesoporous graphitic carbon nitride (mpg-C3N4). This method provides a universally applicable approach for synthesizing highly pure diatomic catalysts. Furthermore, the dual-atom Pd catalyst exhibits an outstanding turnover frequency of 5819 h(-1) in the hydrogenation of nitrobenzene, surpassing that of both single-atom Pd and Pd-2057 clusters. Density functional theory calculations reveal that excellent hydrogenation performance benefits from the easier dissociation of H-H bonds at the atomic geminal Pd-2 sites in the hydrogenation process of nitrobenzene compared to that of single-atom Pd and Pd clusters. This work presents a universal synthetic strategy for precisely constructing multimetal atomic centers, showcasing the advantages of geminal metal sites in catalyzing multimolecule-involved reactions.

关键词： magnetron sputtering size-selected mass spectrum atomic-level dual-atom catalyst synergisticeffect

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Immobilizing graphitic carbon nitride on porous silica via hydrogen bonds for photocatalytic flow synthesis of azoxybenzene

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CHEMICAL ENGINEERING JOURNAL 2023年 476卷

作者： Liu, wuwen Zhang, Dongsheng Yue, Huiyu Li, Yajiao Rosei, Federico Liu, Dong Su, Ren Soochow Univ Soochow Inst Energy & Mat Innovat SIEMIS Suzhou 215006 Peoples R China Univ Sci & Technol China Sch Chem & Mat Sci Hefei 230026 Anhui Peoples R China Univ Sci & Technol China Suzhou Inst Adv Res Suzhou 215123 Jiangsu Peoples R China Univ Trieste Dept Chem & Pharmaceut Sci Via Giorgeri 1 I-34127 Trieste Italy

Heterogeneous photocatalysis is an ideal method for eco-friendly synthesis of value-added chemicals. However, due to the limited penetration depth of photons and inefficient utilization of the catalytic active sites, the scalability of heterogeneous photocatalysis is restrained. Combining heterogeneous photocatalysis and flow system is a promising solution to optimize the light absorption and mass transfer;however, an affordable, practical design of the flow system and the immobilization method of the photocatalyst is still missing. Here, we report a flow system for heterogeneous photocatalytic synthesis of azoxybenzene and its derivatives from reductive coupling of nitrobenzene at a gram-scale using anchored graphitic carbon nitride (gCN) on porous silica (gCN-SiO2). The hydrogen bonds formed between the gCN and the tetramethoxysilane (TMOS) precursor during the dehydrative condensation process prevent unwanted leaching of catalyst, enabling photocatalytic flow synthesis of azoxybenzene with high selectivity, efficiency, and durability. Mechanistic studies reveals that the gCN-SiO2 regulates the photocatalytic reduction kinetics of nitrobenzene by facilitating the generation of nitrosobenzene and N-phenylhydroxylamine intermediates while preventing the formation of unwanted 4-phenylazophenol byproducts, resulting in efficient and selective synthesis of azoxybenzene. Our work provides an alternative path towards large scale heterogeneous photocatalysis.

关键词： Flow synthesis Heterogeneous photocatalysis Graphitic carbon nitride Hydrogen bonding Azoxybenzene

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新时代东北全面振兴战略下营商环境优化问题刍议

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哈尔滨市委党校学报 2024年第1期 29-35页

作者：武文莉王濛中共吉林省委党校(吉林省行政学院) 长春130012

习近平总书记2023年9月在新时代推动东北全面振兴座谈会上强调,东北全面振兴要进一步优化政治生态,营造良好的营商环境。随着东北地区各级政府对营商环境的重视,东北营商环境纵向比较取得显著成效,但营商环境没有最好,只有更好。横向比... 详细信息

习近平总书记2023年9月在新时代推动东北全面振兴座谈会上强调,东北全面振兴要进一步优化政治生态,营造良好的营商环境。随着东北地区各级政府对营商环境的重视,东北营商环境纵向比较取得显著成效,但营商环境没有最好,只有更好。横向比较在政务服务、市场环境、法治环境以及创新方面依然存在提升的空间。本文从营造务实高效的政务环境、构建亲商安商的市场环境、培育规范有序的法治环境以及打造助推企业的创新环境等方面对优化东北营商环境提出对策建议。

关键词：东北全面振兴营商环境数字政府建设

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DVFS-based Energy-saving Workflow Offloading Strategy in Mobile Edge Computing Environments

DVFS-based Energy-saving Workflow Offloading Strategy in Mob...

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International Conference on Computer Supported Cooperative Work in Design

作者： Bo Li wuwen Chen Shicheng Jin Yuhao Shi School of Information Science and Engineering Yunnan University Kunming China

As the number and proportion of compute-intensive tasks on mobile devices increase, so does the amount of energy required to process them. Edge computing technologies provide a solution to enhance the capacity of mobile devices by offloading those tasks to edge servers. Based on dynamic voltage and frequency scaling (DVFS) technology, this paper proposed a new energy saving offloading strategy for mobile devices. On the premise that the task completion time meets the task deadline, the energy consumption problem of mobile devices is formulated as a minimum problem and solved by the genetic algorithm. In this strategy, priority is allocated to each task of workflow, and corresponding offloading resources are allocated according to the result of classification. DVFS technology is applied to the CPU of the terminal device to further reduce energy consumption while the task-resource mapping is performed. Experimental results show that for the same workflow and the same offloading resources and communication environment, in meet the delay constraints of tasks, the proposed algorithm is compared with the existing fine-grained task migration energy-saving algorithm based on genetic algorithm and the task scheduling algorithm based on energy consumption perception, can effectively improve the high energy consumption of mobile devices.

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Synthesis of highly ordered TiO2-Al2O3 and catalytic performance of its supported NiMo for HDS of 4, 6-dimethyldibenzothiophene

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CATALYSIS TODAY 2023年 423卷

作者： Zhang, Pengfei Mu, Fujun Zhou, Yasong Wei, Qiang Liu, Xiaodong You, Qingxiang Shan, Yacheng Zhou, wuwen China Univ Petr State Key Lab Heavy Oil Proc Beijing 102249 Peoples R China Xian Univ Sci & Technol Sch Chem & Chem Engn Xian 710054 Peoples R China

The highly ordered mesoporous TiO2-Al2O3 composite oxides were prepared via a facile evaporation-induced self-assembly (EISA) method. All of those synthesized materials were characterized by means of XRD, XRF, N2 adsorption, FTIR, Py-FTIR and TEM. The results show that the hexagonally ordered mesoporous TiO2-Al2O3 oxides with high specific surface area, high thermal stability and narrow pore size distributions were successfully synthesized by EISA. The corresponding NiMo catalysts supported on TiO2-Al2O3 oxides were further characterized by H2-TPR, HRTEM and XPS. Their hydrodesulfurization catalytic performances were tested in a fixedbed reactor, using 4,6-dimethyldibenzothiophene as the probe. The analyzing results exhibit that the incorporation of TiO2 could effective weaken the support-metal interactions, thus enhancing the reduction degree of active metals and forming more "Type II" Ni-Mo-S active phases that would be beneficial for the HDS of highly refractory organosulfur compound. The catalytic results reveal that the 4,6-DMDBT conversion over NiMo/TA-n catalysts gradually increased as the Ti/Al molar ratio increases, and reaches a maximum values at NiMo/TA-0.4. The NiMo/TA-0.4 exhibited the highest hydrodesulfurization catalytic performance of 4,6-DMDBT due to the synergistic effect of suitable textural properties, high thermal stability and moderate metal-support interactions.

关键词： Evaporation -induced self -assembly Hydrodesulfurization 6-Dimethyldibenzothiophene

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重水对萎缩芽孢杆菌芽孢萌发的影响

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生物化学与生物物理进展 2021年第10期48卷 1196-1203页

作者：常金辉吴文捷香港理工大学深圳研究院深圳518052 中国科学院大学附属肿瘤医院(浙江省肿瘤医院) 中国科学院基础医学与肿瘤研究所杭州310022 浙江省放射肿瘤学重点实验室杭州310022

本研究快报报道了重水对细菌芽孢的萌发及其可培养性的抑制作用.在常温条件下,用L-丙氨酸触发细菌芽孢的萌发,并用Tb-DPA荧光法、相差显微镜观测法和光密度测定法监测萌发过程,用最终萌发水平、萌发半期、萌发速度3个参数来表征萌发过程... 详细信息

本研究快报报道了重水对细菌芽孢的萌发及其可培养性的抑制作用.在常温条件下,用L-丙氨酸触发细菌芽孢的萌发,并用Tb-DPA荧光法、相差显微镜观测法和光密度测定法监测萌发过程,用最终萌发水平、萌发半期、萌发速度3个参数来表征萌发过程.除此之外,我们还用菌落形成单位的个数来评估萌发后芽孢的可培养性.结果表明,重水对整个萌发过程有抑制作用,同时降低了萌发后芽孢的可培养性,但对最终萌发水平无影响.我们推测这是因为重水增强了一些芽孢特异性信号蛋白的稳定性.

关键词：重水萎缩芽孢杆菌芽孢萌发可培养性

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