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Differences in Brain Structural Covariance Network Characteristics in Children and Adults With Autism Spectrum Disorder

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AUTISM RESEARCH 2021年第2期14卷 265-275页

作者： Cai, Suping Wang, xuwen Yang, Fan chen, Dihui Huang, Liyu Xidian Univ Sch Life Sci & Technol Xian 710071 Shaanxi Peoples R China

Systematically describing the structural topological configuration of human brain during development is an essential task. Autism spectrum disorder (ASD) represents a powerful challenge for psychiatry and neuroscience researchers. In this study, we investigated variations in the structural covariance network properties of 441 patients with ASD ranging in age from 7 to 45 years and in 426 age-matched healthy controls (HCs) using structural magnetic resonance neuroimaging from the ABIDE database. We applied a sliding window approach to study topological variation during development using comprehensive graph theoretical analysis. The main findings are as follows: (1) Cross-sectional trajectories of the network characteristics exhibited inverted U-shapes in both HCs and participants with ASD, with the latter exhibiting a 7-year delay in reaching the maximum value, (2) network resilience to targeted attacks peaked at 18 ' and 19 ' in the HCs and at 25 ' in the participants with ASD, and the weakest resilience occurred at age 7 ', (3) the HCs and participants with ASD exhibited normalized mean degree differences in the right amygdala, and (4) significant differences in the network characteristics were observed in the 18 ' age group at most of the densities analyzed. We used cross-sectional analysis to infer distinct neurodevelopmental trajectories in ASD in the brain structural connectome. Our findings are consistent with the notion that adolescence is a sensitive period of brain development with strong potential for brain plasticity, offering opportunities for environmental adaptation and social integration and for increasing vulnerability. ASD may be a product of susceptibility. Lay Summary We used cross-sectional analysis to preliminarily infer distinct neurodevelopmental trajectories in ASD in the brain structural connectome. The main findings are as follows: (1) Cross-sectional trajectories of the network characteristics exhibited inverted U-shapes in both HCs and pa

关键词： structure covariance network autism spectrum disorder sliding window analysis graph theoretical analysis brain development structural magnetic resonance neuroimaging

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Thermal-mechanical coupling in drilling high-performance CFRP: Scale-span modeling and experimental validation

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COMPOSITE STRUCTURES 2024年 331卷

作者： Liu, Yong Pan, Zitao Zhang, Hao Jing, xuwen Zhou, Honggen chen, Yong Jiangsu Univ Sci & Technol Coll Mech Engn Zhenjiang 212003 Peoples R China Yancheng Inst Technol Sch Automot Engn Yancheng 224051 Peoples R China

The focus of this study is to explore a scale -span thermal-mechanical coupling method for predicting the dynamic mechanical progressive failure behaviors and predicting thermal damage during the drilling process of Carbon Fiber Reinforced Plastic (CFRP). Initially, a thermal conduction constitutive model of drilling CFRP was developed based on the proposed thermal distribution ratio calculation method. Meanwhile, a dynamic spanscale progressive damage constitutive model for CFRP, incorporating modified micromechanics failure criterion with bilinear damage evolution laws, was proposed, and a bilinear cohesive model, including three damage modes, is employed to simulate interlaminar delamination. Subsequently, a user -defined material subroutine VUMAT was implemented on the ABAQUS/Explicit platform to simulate the thermal-mechanical coupling behaviors of drilling T700S-12K/YPH-23 CFRP using a twist drill bit. Finally, a comprehensive information monitoring platform for CFRP drilling experiments was established to validate the accuracy of the simulation results by considering drilling temperature, thrust force, and hole -wall morphology. The results demonstrate excellent agreement between the established thermal-mechanical coupling span -scale model and the experimental data. Furthermore, the simulation effectively captures the various damage behaviors and thermal conduction phenomenon, that occur during the intact drilling process.

关键词： CFRP Drilling Scale -span Thermal -mechanical coupling Progressive failure

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A cohort of five cases with asymmetric conjoined twining and literature review

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PEDIATRIC SURGERY INTERNATIONAL 2022年第1期38卷 169-181页

作者： Zhi, Xiufang Hu, Bo Zhao, xuwen chen, Jing Gu, Chunyu Pu, Linjie Fang, Yulian Cai, Chunquan Tianjin Med Univ Grad Coll Tianjin 300070 Peoples R China Tianjin Univ Childrens Hosp Tianjin Childrens Hosp Tianjin 300134 Peoples R China Tianjin Childrens Hosp Dept Neonatal Surg Tianjin 300134 Peoples R China Tianjin Childrens Hosp Dept Radiol Tianjin 300134 Peoples R China Tianjin Pediat Res Inst Tianjin 300134 Peoples R China Tianjin Key Lab Birth Defects Prevent & Treatment Tianjin 300134 Peoples R China Tianjin Childrens Hosp Dept Neurosurg 238 Longyan Rd Tianjin 300134 Peoples R China

Purpose Asymmetric conjoined twining (ACT) is a form of conjoined twining which is a rare malformation of monochorionic monoamniotic twin pregnancy. Most publications were single case reports. We reported a cohort of five cases with ACT from a single tertiary medical center and reviewed the case reports of ACT over the last decade to enrich the clinical research of this disease and summarized the clinical features of the disease. Methods We reviewed five cases of ACT admitted in Tianjin Children's Hospital from 17 March, 2008, through 7 March 2017. The cohort was analysed from general information, imaging manifestations, separation surgery, histopathological findings, outcome and follow-up. We searched the English literatures on case reports of ACT over the past decade from the PubMed database and presented details about the clinical characteristics, treatment, and prognosis of all cases. Results There were four males and one female in our cohort. Among the five cases, two parasites were located in epigastrium, two in rachis, and one in retroperitoneum (fetus in fetu, FIF). All of the parasites were separated successfully by operation in five cases and were confirmed to be ACT by histopathology reports. Four patients made an uneventful recovery except for one case of wound infection. All of them were doing well in follow-up. In the literature review, we found 41 cases of exoparasitic heteropagus twining (EHT) and 63 cases of FIF. Conclusions ACT is very rare and usually diagnosed by prenatal ultrasonography (US). Computed tomography (CT) and magnetic resonance imaging (MRI) examinations are essential imaging examinations before separation surgery to delineate the anatomical relationship between the autosite and the parasite. In general, the separation surgery of ACT is less complicated and the prognosis is better compared with the symmetric conjoined twining (SCT).

关键词： Asymmetric conjoined twining Separation surgery Autosite Parasite

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A novel finer soil strength mapping framework based on machine learning and remote sensing images

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COMPUTERS & GEOSCIENCES 2024年 182卷

作者： Wang, Ruizhen Wan, Siyang chen, Weitao Qin, xuwen Zhang, Guo Wang, Lizhe China Univ Geosci Key Lab Geol Survey & Evaluat Minist Educ Wuhan 430074 Peoples R China China Univ Geosci Fac Comp Sci Wuhan 430074 Peoples R China China Geol Survey Basic Survey Dept 45 Fuwai St Beijing 100037 Peoples R China

Soil strength is an important factor for assessing the vehicle trafficability in the wilds and making reliable offroad path planning. Rating Cone index (RCI) has been widely used as an indicator of soil strength for mobility assessment. Currently, regional RCI are mainly obtained by using Soil Moisture Strength Prediction (SMSP) Model based on the Unified Soil Classification System (USCS) soil types and soil moisture at critical depth. However, USCS classification is inaccessible directly in most soil databases. And current soil moisture products are of coarse spatial resolution and only reliable in soil surface layer. It is costly to arrange ground survey for USCS soil type and the fine soil moisture in deeper layers cannot be obtained directly. To fill this gap, a novel framework is proposed to generate finer RCI-based soil strength map. To gain USCS soil classification in an un-surveyed study site, RF, GBDT, XGBoost and LCE ensemble learning models were trained with data from gSSURGO Database which contains USCS soil types and soil properties, and then make prediction on data from SoilGrids Database by using same properties. Then, to obtain the finer soil moisture of critical depth, these treebased models were constructed with ground observation data, Sentinel-2 images, topographical data and soil properties with higher spatial resolution. The SMSP model is finally used to generate the finer daily soil strength map for the study site. The proposed framework highly improved the resolution and reliability of existing soil strength map generating methods, and can provide detailed soil strength information.

关键词： Soil strength Rating cone index Machine learning Soil moisture

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Transform Sequential Data to Image for Detecting Covert Timing Channel

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International Journal of Network Security 2024年第2期26卷 224-234页

作者： Huang, xuwen chen, Yonghong Zhuang, Xiaolong Lin, Yuwei School of Computer Science and Technology Huaqiao University China Xiamen Key Laboratory of Data Security and Blockchain Technology Huaqiao University Xiamen Fujian 361000 China

The network covert timing channel utilizes inter-packet delay to encode binary data to achieve information leakage and other purposes. In recent years, Covert Timing Channels (CTCs) have been demonstrated to be applicable across various protocols and networks, posing a significant threat to network security. Simultaneously, new CTCs have challenged the efficacy of CTC detection schemes. The recent ϵ-κlibur and ϵ-κlibur-O channels exhibit structural and characteristic similarities to legitimate channels, rendering ML-based detection methods like GAS and Snap ineffective. In this paper, we investigate an approach based on Gramian Angular Field (GAF), Markov Transition Field (MTF), and Recurrence Plot (RP) image processing. We further employ the knowledge-distilled and compressed image classification model MobileVit for detection. Our approach achieves a detection rate 98.24% for seven different channels within a sampling window of 64 IPDs. Experimental results demonstrate our proposed scheme’s generality, sensitivity, and effectiveness. © 2024, Femto Technique Co.. All rights reserved.

关键词： Distillation

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Online Monitoring of Ship Block Construction Equipment Based on the Internet of Things and Public Cloud: Take the Intelligent Tire Frame as an Example

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KSII TRANSACTIONS ON INTERNET AND INFORMATION SYSTEMS 2021年第11期15卷 3970-3990页

作者： Cai, Qiuyan Jing, xuwen chen, Yu Liu, Jinfeng Kang, Chao Li, Bingqiang Jiangsu Univ Sci & Technol Sch Mech Engn Zhenjiang 212100 Jiangsu Peoples R China

In view of the problems of insufficient data collection and processing capability of multi source heterogeneous equipment, and low visibility of equipment status at the ship block construction site. A data collection method for ship block construction equipment based on wireless sensor network (WSN) technology and a data processing method based on edge computing were proposed. Based on the Browser/Server (B/S) architecture and the OneNET platform, an online monitoring system for ship block construction equipment was designed and developed, which realized the visual online monitoring and management of the ship block construction equipment status. Not only that, the feasibility and reliability of the monitoring system were verified by using the intelligent tire frame system as the application object. The research of this project can lay the foundation for the ship block construction equipment management and the ship block intelligent construction, and ultimately improve the quality and efficiency of ship block construction.

关键词： Ship block construction equipment monitoring WSN edge computing Web

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A bioorthogonal assembly based on metallophilic interactions for selective imaging and PDT treatment of cancer cells

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INORGANIC CHEMISTRY FRONTIERS 2022年第10期9卷 2290-2297页

作者： Da, xuwen Yu, Fei-Hu Zhang, Chao Wang, Zhanhua Jian, Yao Hou, Yuanjun chen, Yong Wang, Xuesong Zhou, Qianxiong Chinese Acad Sci Tech Inst Phys & Chem Key Lab Photochem Convers & Optoelect Mat Beijing 100190 Peoples R China Univ Chinese Acad Sci Beijing 100049 Peoples R China

Precise control of luminescence and singlet oxygen generation is important for selective photo-theranostic applications. In this work, bioorthogonal assembly based on d(10)MIDLINE HORIZONTAL ELLIPSISd(10) metallophilic interactions was first proposed for selective cancer cell imaging and photodynamic therapy (PDT) treatment as a proof of concept. [Au(NHC)(2)](+) (NHC = N-heterocyclic carbene) cations loaded on hyaluronic acid were selectively taken up by cancer cells. The subsequent incubation with [MX2](-) (M = Au or Cu and X = halide or arylacetylide) anions led to the bioorthogonal assembly of C3 + A5/A10 in cancer cells with luminescence turn-on and singlet oxygen generation upon irradiation. This work not only demonstrates that d(10)MIDLINE HORIZONTAL ELLIPSISd(10) metallophilic interactions can be readily harnessed for developing bioorthogonal assembly to realize precise cancer cell imaging and PDT, but also can stimulate the development of supramolecular interaction based bioorthogonal chemistry.

关键词： Cancer cells

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基于物流管理的防窜码前关联软件设计与实现

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物流技术 2019年第6期38卷 84-88,115页

作者：陈延文陈旭文管永天水师范学院电子信息与电气工程学院甘肃天水741001 兰州达嘉喷码标识设备有限公司甘肃兰州730050

为解决食品饮料行业中的包装赋码与关联问题,设计了基于物流管理的防窜码前关联软件系统,介绍了该系统的功能模块与结构、流程以及软硬件接口、运行设计,最后结合系统的逻辑设计进一步说明了该软件系统的工作原理与特点。

关键词：物流管理防窜码前关联研华PCI卡

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Effect of grinding depth on the rotating bending fatigue properties of 40Cr steel

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FATIGUE & FRACTURE OF ENGINEERING MATERIALS & STRUCTURES 2022年第4期45卷 1292-1295页

作者： Zhou, Honggen chen, Jianzhi Bai, Xiaoxiang Li, Guochao Guan, Xiaoyan Du, Qin Li, Ning Jing, xuwen Jiangsu Univ Sci & Technol Sch Mech Engn Zhenjiang 212003 Jiangsu Peoples R China Beijing North Vehicle Grp Co Ltd Beijing Peoples R China

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Investigation of mechanical and electronic properties of a novel quaternary transition-metal nitride Ti0.25W0.25V0.25Ta0.25N

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MATERIALS CHEMISTRY AND PHYSICS 2023年 310卷

作者： Xie, Quanmin Liu, xuwen Zhang, Zheng Nian, Xinzhe chen, Lei Jianghan Univ State Key Lab Precis Blasting Wuhan 430056 Peoples R China Jianghan Univ Hubei Key Lab Blasting Engn Wuhan 430056 Peoples R China Sichuan Jiaoda Engn Detect & Consulting Co Ltd Chengdu Peoples R China Baoji Univ Arts & Sci Coll Phys & Optoelect Technol Baoji 721016 Peoples R China

Multi-element transition-metal nitrides possessing combinations of outstanding mechanical and physical properties have attracted increasing attention due to its potential applications. Here, a new transition-metal nitride alloying four metal elements of Ti, W, V and Ta is proposed, in which the doping ratios of these four metal elements are equal. Using an improved structure searching method, the potential structures with low enthalpies were fully explored. An orthorhombic structure was firstly disclosed and verified to be its ground-state phase. It is the most energetically favorable structure in the pressure of 0 similar to 100 GPa. The phonon spectrum calculations demonstrated its lattice dynamical stability. Systematic study of its mechanical properties showed the orthorhombic structure not only possessed a large hardness of 32.4 GPa but also behaved a large indentation shear strength of about 30 GPa, greatly exceeding its well-known fcc-B1 phase (about 15 GPa). Meanwhile, we also compared the orthorhombic phase to its disordered structure within B1 phase by generating special quasirandom structures (SQS) with a 3 x 3 x 3 supercell (216 atoms), which can be viewed as its high-entropy phase. The results displayed this SQS system had comparable hardness and strength but greatly improved ductility and toughness relative to the ordered B1 phase.

关键词： Transition-metal nitride First-principles Mechanical properties Ideal strength Electronic structure

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