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海洋地质与第四纪地质 2021年第2期41卷 173-180页

作者：曹全斌曹旭文鲁银涛陈宇航闫春许小勇王朝锋中国石油杭州地质研究院杭州310023 自然资源部第二海洋研究所杭州310012 西安石油大学西安710065

利用高分辨率三维地震资料、测井和钻井数据,对东非鲁伍马盆地深水沉积特征进行了系统刻画。根据深水沉积体的地震相特征,识别出峡谷、水道、漫溢沉积、朵体、块体搬运沉积(MTDs)和凝缩段等深水沉积单元,建立了地震识别图版。分析总结... 详细信息

利用高分辨率三维地震资料、测井和钻井数据,对东非鲁伍马盆地深水沉积特征进行了系统刻画。根据深水沉积体的地震相特征,识别出峡谷、水道、漫溢沉积、朵体、块体搬运沉积(MTDs)和凝缩段等深水沉积单元,建立了地震识别图版。分析总结了水道和朵体的岩性特征、电性特征和储层物性特征,砂岩具有低伽马(GR)和高电阻(RT)特征,厚层砂岩GR曲线呈“箱型”,有泥岩夹层的砂岩段呈叠加的“钟型”特点;储层压实程度弱,发育原生粒间孔隙,具有中—高孔、中—高渗的特征。结合成藏条件研究,认为由水道和朵体浊积砂岩储层、凝缩段和漫溢沉积泥岩盖层、天然堤和MTDs为侧向遮挡等要素构成的油气储、盖配置关系,是研究区油气成藏的一个关键因素,对深水油气勘探具有一定的指导意义。

关键词：深水沉积特征沉积结构单元油气勘探东非鲁伍马盆地

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南海海盆区莫霍面分布规律及其对深部钻探的意义

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地质学报 2022年第8期96卷 2635-2646页

作者：秦绪文张宝金赵斌路允乾陈玺王利杰许振强张如伟耿明会杨振李建平吕文超尉建功中国地质调查局北京100037 中国地质调查局广州海洋地质调查局广东广州510075 南方海洋科学与工程广东省实验室(广州) 广东广州511458

钻遇莫霍面是人类一直以来的梦想。深海海底是地球上离莫霍面最近的地方,目前有研究推测南海是世界上莫霍面深度最浅的海域之一,但缺乏足够的直接证据。深反射地震探测可以直接揭示岩石圈的构造形态,是莫霍面探测的重要手段。本文基于长... 详细信息

钻遇莫霍面是人类一直以来的梦想。深海海底是地球上离莫霍面最近的地方,目前有研究推测南海是世界上莫霍面深度最浅的海域之一,但缺乏足够的直接证据。深反射地震探测可以直接揭示岩石圈的构造形态,是莫霍面探测的重要手段。本文基于长达15000 km的深反射多道地震剖面的解释、处理、制图和分析,结合前人的研究,形成了南海海盆区莫霍面反射特征和空间分布的初步认识。①南海东部次海盆南部早期经历了较快速扩张,岩浆供应充足,受扩张停止后岩浆活动影响较小,基底平坦,地质构造相对简单,同时洋壳地震速度结构不存在异常,且有较强的广角莫霍面反射波和可识别的地幔顶部折射波,具备莫霍面钻探的基本条件。②南海海盆不同区域的莫霍面反射强度存在较大差异。其中东部次海盆莫霍面反射最为强烈且清晰,西北次海盆次之,西南次海盆仅有零星出现的清晰莫霍面反射且可信度不高。③识别南海海盆区莫霍面地震反射长度超过3500 km,首次形成了海盆区深度域莫霍面地震反射空间分布图。与重力反演的莫霍面深度相比,利用深反射多道地震计算的莫霍面深度细节更为丰富,并且可以在垂向上清晰刻画莫霍面的结构。整体上,南海海盆区莫霍面地震反射强烈和可信度高的区域中,深度较浅的区域之一是东部次海盆南部,最浅处仅约9.5 km,其中水深4.01 km,洋壳厚度仅5.54 km。综合判断,东部次海盆南部是南海重要的莫霍面钻探备选区,这对南海莫霍面钻探选址具有重要意义。

关键词：南海深反射多道地震莫霍面洋壳地震速度模型钻探选址

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The mobility of thallium in sediments and source apportionment by lead isotopes

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CHEMOSPHERE 2019年 219卷 864-874页

作者： Liu, Juan Yin, Meiling Luo, xuwen Xiao, Tangfu Wu, Zhifeng Li, Nuo Wang, Jin Zhang, Weilong Lippold, Holger Belshaw, Nick Stanley Feng, Yuexing chen, Yongheng Guangzhou Univ Sch Environm Sci & Engn Inst Environm Res Greater Bay Minist EducKey Lab Water Qual & Conservat Pearl Guangzhou 510006 Guangdong Peoples R China Univ Oxford Dept Earth Sci Oxford OX1 3AN England Helmholtz Zentrum Dresden Rossendorf Inst Ressourcenokol D-04318 Leipzig Germany Univ Queensland Sch Earth & Environm Sci Brisbane Qld 4072 Australia

Thallium (TI) is a very toxic heavy metal. As a part of ongoing investigations, the mobility, sources and fate of TI were investigated for sediments from a watershed in the northern part of the Pearl River, South China, whose catchment has been seriously impacted by large-scale Pb Zn smelting activities onshore. A wide dispersion of severe TI contamination was observed throughout the depth profiles. A modified IRMM (Institute for Reference Materials and Measurements, Europe) sequential extraction procedure of a selected depth profile uncovered an exceptionally high enrichment of TI in geochemically-mobile fractions (i.e., weak-acid-exchangeable, reducible and oxidizable fractions), on average 5.94 +/- 2.19 mg/kg (74.6% +/- 5.1% of the total TI content) not only in the surface sediments but also in deep sediments. The proximal quantitative source apportionment using Pb isotopic fingerprinting technique indicated that a majority (80%-90%) of TI contamination along the depth profiles is anthropogenically derived from the Pb Zn smelting wastes. The results highlight the pivotal role of smelting activities in discharging huge amounts of geochemically-mobile TI to the sediments down to approximately 1 m in length, which is quantitatively evidenced by Pb isotopic tracing technique. Lead isotopes combined with distribution of TI and Pb contents identified a potential marker for a point source from the Pb Zn smelter in the river catchment, which also provides a theoretical framework for source apportionment of metal contamination in a larger river/marine system and in other sulfide mining/smelting areas likewise. (C) 2018 Elsevier Ltd. All rights reserved.

关键词： Thallium mobility Lead isotopes Source apportionnient Pb Zn smelting

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Optimized expression of classical swine fever virus E2 protein via combined strategy in Pichia pastoris

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PROTEIN EXPRESSION AND PURIFICATION 2020年 167卷 105527页

作者： Li, Ding Wu, Junchen chen, Jin Zhang, Dong Zhang, Yuanpeng Qiao, xuwen Yu, Xiaoming Zheng, Qisheng Hou, Jibo Jiangsu Acad Agr Sci Inst Vet Immunol & Engn Nanjing Peoples R China Yangzhou Univ Jiangsu Coinnovat Ctr Prevent & Control Important Yangzhou Jiangsu Peoples R China Minist Sci & Technol Jiangsu Key Lab Food Qual & Safety State Key Lab Cultivat Base Beijing Peoples R China Shandong Prov Ctr Anim Dis Control & Prevent Jinan Shandong Peoples R China

Precaution of classical swine fever (CSF) is an important mission for the worldwide swine industry. Glycoprotein E2 is the leading antigen candidate for subunit vaccine of classical swine fever virus (CSFV). In this study, two Spy-tagged E2 genes were synthesized in vitro and subcloned into pMCO-AOX vector for intracellular expression in Pichia pastor-is after methanol induction. Western blot analysis and semi-quantitative analysis showed that the yield of recombinant E2 protein was improved 17.87 folds by using co-translocational signal peptide cSIG. After the construction of the tandem multiple copy expression vectors, further increase of E2 production was observed by repetitive transforming expression vectors into P. pastoris genome. Finally, the yeast transformants harboring 8 or 16 copies of cSIG-E2-Spy increased the E2 expression level by 27.01-fold or 30.72-fold, respectively. These results demonstrate that utilizing co-translocational signal peptide together with multi-copy integration strategy can increase the production of recombinant E2 protein efficiently.

关键词： Classical swine fever virus E2 protein Co-translocational signal peptide Multi-copy integration Combined strategy

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Transcriptomic and physiological changes in western mosquitofish (Gambusia affinis) after exposure to norgestrel

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ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY 2019年 171卷 579-586页

作者： Hou, Liping chen, Shanduo Liu, Juan Guo, Jingwen chen, Zhong Zhu, Qiaoling Zhang, Wei Xu, GuoLiang Liang, Ye Wu, Rongrong Fang, xuwen Zhang, Cuiping Xing, Ke Guangzhou Univ Sch Life Sci Guangzhou 510655 Guangdong Peoples R China Shantou Univ Guangdong Prov Key Lab Marine Biotechnol Shantou 515063 Peoples R China Guangzhou Univ Key Lab Water Qual & Conservat Pearl River Delta Guangdong Prov Key Lab Radionuclides Pollut Contr Minist EducInst Environm Res Greater Bay Guangzhou 510006 Guangdong Peoples R China Guangzhou Univ Coll Environm Sci & Engn Guangzhou 510655 Guangdong Peoples R China NanWu Middle Sch Guangzhou 510655 Guangdong Peoples R China Guangzhou Tieyi Middle Sch Guangzhou 510655 Guangdong Peoples R China Rural Nonpoint Source Pollut Comprehens Managemen Guangzhou 510655 Guangdong Peoples R China

Norgestrel (NGT) is a synthetic progestin used in human and veterinary medicine. Adult female mosquitofish were exposed to NGT for 42 d at 377 ng L-1. The fin morphology and the liver transcriptome were assessed. NGT exposure increased ray 4:6 length ratio. As compared to the control, NGT treatment affected the expression of 11,772 annotated transcripts in female mosquitofish. Specifically, we found 5780 were repressed while 5992 were significantly induced. Gene ontology (GO) analysis showed that 53 KEGG (Kyoto Encyclopedia of Genes and Genomes) pathways and 158 GO terms were significantly over expressed. Genes showing the largest magnitude of expression changes were related to fin development, androgen biosynthesis, and lipid and fatty acid metabolisms, suggesting the involvement of these biological processes in response to NGT exposure in G. affinis. This first comprehensive study on the transcriptomic alterations by NGT in G. affinis not only provides valuable information on the development of molecular markers but also opens new avenues for studies on the molecular mechanisms of effects of NGT in particular and possibly other progestins in G. affinis.

关键词： Endocrine disruption Norgestrel Secondary sexual characteristics transcriptomics Gambusia affinis

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骨折顺势复位法结合微创接骨板技术对累及关节面跟骨骨折近期疗效

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青岛大学学报（医学版） 2022年第1期58卷 46-50页

作者：李勇阵刘国明钱源陈峰李绪文季爱玉青岛大学附属医院创伤外科山东青岛266071

目的探讨应用骨折顺势复位法结合微创接骨板技术(MIPO)治疗累及关节面跟骨骨折的近期效果。方法对12例(14侧)累及关节面的跟骨骨折应用骨折顺势复位法结合克氏针撬拨,恢复距下关节面平整及跟骨长度、宽度、高度和Bohler角、Gisane角;选... 详细信息

目的探讨应用骨折顺势复位法结合微创接骨板技术(MIPO)治疗累及关节面跟骨骨折的近期效果。方法对12例(14侧)累及关节面的跟骨骨折应用骨折顺势复位法结合克氏针撬拨,恢复距下关节面平整及跟骨长度、宽度、高度和Bohler角、Gisane角;选择纵向微创切口,采用MIPO技术放置解剖钢板固定骨折。结果12例(14侧)病人术后无切口感染、坏死等并发症出现。术后24 h跟骨长度、跟骨高度、Bohler角、Gisane角明显高于术前,跟骨宽度低于术前,差异有统计学意义(t=12.552~17.011,Z=3.296、3.538,P<0.05)。术后6个月随访,AOFAS踝-后足评分优4侧,良8侧,可2侧。结论运用骨折顺势复位法结合MIPO技术治疗累及关节面跟骨骨折近期效果满意。

关键词：跟骨骨折骨折固定术微创接骨板技术

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Insight into Iron Leaching from an Ascorbate-Oxidase-like Fe−N−C Nanozyme and Oxygen Reduction Selectivity**

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Angewandte Chemie 2023年第27期135卷

作者： xuwen Cao Caixia Zhu Qing Hong Xinghua chen Kaiyuan Wang Prof. Yanfei Shen Prof. Songqin Liu Prof. Yuanjian Zhang Jiangsu Engineering Laboratory of Smart Carbon-Rich Materials and Device Jiangsu Province Hi-Tech Key Laboratory for Bio-Medical Research School of Chemistry and Chemical Engineering Southeast University Nanjing 211189 China Medical School Southeast University Nanjing 210009 China

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南海东部次海盆南侧基底结构与沉积特征及其控制因素

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大地构造与成矿学 2022年第5期46卷 884-897页

作者：赵斌王利杰张宝金耿明会秦绪文张如伟杨振陈玺吕文超张旭东中国地质调查局广州海洋地质调查局广东广州510760 南方海洋科学与工程广东省实验室(广州) 广东广州511458 中国地质调查局北京100037

南海东部次海盆经历了完整的海底扩张过程,对其进行从北至南、从东到西系统的研究有助于进一步认识南海的演化过程。通过南海东部次海盆3条多道地震剖面的解析,对其基底形态、沉积充填和岩浆活动特征进行研究,首次揭露了南海东部次海盆... 详细信息

南海东部次海盆经历了完整的海底扩张过程,对其进行从北至南、从东到西系统的研究有助于进一步认识南海的演化过程。通过南海东部次海盆3条多道地震剖面的解析,对其基底形态、沉积充填和岩浆活动特征进行研究,首次揭露了南海东部次海盆南侧东西向的沉积-构造特征。结果表明,南海东部次海盆南侧基底主要分为两种类型:一种为崎岖不平、深海丘陵和海山发育,且基底隆起表现为“东高西低”;另一种基底相对平坦,局部有岩浆侵入。两种基底形态受海底扩张速率、板片俯冲挠曲和扩张后岩浆活动等因素综合控制。东部次海盆南部的沉积充填类型主要有3种,受构造、沉积作用和物源供给共同控制,总体上呈现出邻近扩张脊一侧沉积薄、靠南部陆缘一侧沉积厚;东部边缘因构造挠曲等因素,基底构造隆起更强,形成较薄沉积,厚度最小处约160 m。基于沉积-构造-岩浆特征,构建东部次海盆南部海底扩张末期以来(16 Ma至今)的沉积-构造演化模型,对南海形成演化研究具有重要意义。

关键词：基底形态海盆沉积岩浆供应沉积-构造演化南海东部次海盆

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CEPC Technical Design Report - Accelerator (v2)

arXiv

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arXiv 2023年

作者： Abdallah, Waleed De Freitas, Tiago Carlos Adorno Afanaciev, Konstantin Ahmad, Shakeel Ahmed, Ijaz Ai, Xiaocong Aleem, Abid Altmannshofer, Wolfgang Alves, Fabio An, Weiming An, Rui Anderle, Daniele Paolo Antusch, Stefan Arai, Yasuo Arbuzov, Andrej Arhrib, Abdesslam Ashry, Mustafa Bai, Sha Bai, Yu Bai, Yang Bairathi, Vipul Balazs, Csaba Bambade, Philip Ban, Yong Bandyopadhyay, Triparno Bao, Shou-Shan Barber, Desmond P. Bat, Ayse Batozskaya, Varvara Behera, Subash Chandra Belyaev, Alexander Bertucci, Michele Bi, Xiao-Jun Bi, Yuanjie Bian, Tianjian Bianchi, Fabrizio Biekötter, Thomas Biglietti, Michela Bilanishvili, Shalva Binglin, Deng Bodrov, Denis Bogomyagkov, Anton Bondarenko, Serge Boogert, Stewart Boonekamp, Maarten Borri, Marcello Bosotti, Angelo Boudry, Vincent Boukidi, Mohammed Boyko, Igor Bozovic, Ivanka Bozzi, Giuseppe Brient, Jean-Claude Budzinskaya, Anastasiia Bukhari, Masroor Bytev, Vladimir Cacciapaglia, Giacomo Cai, Hua Cai, Wenyong Cai, Wujun Cai, Yijian Cai, Yizhou Cai, Yuchen Cai, Haiying Cai, Huacheng Calibbi, Lorenzo Cang, Junsong Cao, Guofu Cao, Jianshe Chance, Antoine Chang, Xuejun Chang, Yue Chang, Zhe Chang, Xinyuan Chao, Wei Chatrabhuti, Auttakit Che, Yimin Che, Yuzhi chen, Bin chen, Danping chen, Fuqing chen, Fusan chen, Gang chen, Guoming chen, Hua-Xing chen, Huirun chen, Jinhui chen, Ji-Yuan chen, Kai chen, Mali chen, Mingjun chen, Mingshui chen, Ning chen, Shanhong chen, Shanzhen chen, Shao-Long chen, Shaomin chen, Shiqiang chen, Tianlu chen, Wei chen, Xiang chen, Xiaoyu chen, Xin chen, Xun chen, Xurong chen, Ye chen, Ying chen, Yukai chen, Zelin chen, Zilin chen, Boping chen, Chunhui cheng, Hok Chuen cheng, Huajie cheng, Shan cheng, Tongguang Chi, Yunlong Chimenti, Pietro Chiu, Wen Han Cho, Guk Chu, Ming-Chung Chu, Xiaotong Chu, Ziliang Coloretti, Guglielmo Crivellin, Andreas Cui, Hanhua Cui, Xiaohao Cui, Zhaoyuan D'Anzi, Brunella Dai, Ling-Yun Dai, Xinchen Dai, xuwen De Maria, Antonio De Filippis, Nicola De La Taille, Christophe De Mori, Francesca De Sio, Chiara Del Core, Elisa Deng, S Agh University of Science and Technology Faculty of Physics and Applied Computer Science Krakow Poland Anhui University Anhui Hefei China Applied Physics Department Federal Urdu University of Arts Science and Technology Islamabad Pakistan Banaras Hindu University Institute of Science Varanasi India Bandirma Onyedi Eylul University Bandirma Turkey Beihang University Beijing China Beijing Computational Science Research Center Beijing China Beijing Conveyi Ltd Beijing China Beijing Glass Research Institute Co. Ltd Beijing China Beijing Institute of Technology Beijing China Beijing Normal University Beijing China Brown University ProvidenceRI United States Budker Institute of Nuclear Physics Novosibirsk Russia Cadi Ayyad University Laboratory of Fundamental and Applied Physics Polydisciplinary Faculty Marrakech Morocco Cairo University Giza Egypt Center for Theory and Computation National Tsing Hua University Hsinchu Taiwan Central China Normal University Hubei Wuhan China Central South University Hunan Changsha China Centro de Fisica Teorica de Particulas Universidade Tecnica de Lisboa Lisboa Portugal Chengdu KaitengSifang Digital Radio & Tv Equipment Co. Ltd Sichuan Chengdu China China Academy of Engineering Physics Sichuan Mianyang China China Building Materials Academy Beijing China China Center of Advanced Science and Technology Beijing China China Institute of Atomic Energy Beijing China China Jiliang University Zhejiang Hangzhou China China Nuclear Instrument CO. Ltd Beijing China China University of Geosciences Beijing China China University of Geosciences Hubei Wuhan China China University of Mining and Technology Jiangsu Xuzhou China China West Normal University Sichuan Nanchong China Chongqing University Department of Physics Chongqing China Chulalongkorn University Bangkok Thailand City University of Hong Kong Department of Physics Hong Kong Cockcroft Institute Daresbury United Kingdom Cornell University IthacaNY

The Circular Electron Positron Collider (CEPC) is a large scientific projectinitiated and hosted by China, fostered through extensive collaboration withinternational partners. The complex comprises four accelerators: a 30 GeVLinac, a 1.1 GeV Damping Ring, a Booster capable of achieving energies up to180 GeV, and a Collider operating at varying energy modes (Z, W, H, and ttbar).The Linac and Damping Ring are situated on the surface, while the Booster andCollider are housed in a 100 km circumference underground tunnel, strategicallyaccommodating future expansion with provisions for a Super Proton ProtonCollider (SPPC). The CEPC primarily serves as a Higgs factory. In its baselinedesign with synchrotron radiation (SR) power of 30 MW per beam, it can achievea luminosity of 5e34 /cm^2/s^1, resulting in an integrated luminosity of 13 /abfor two interaction points over a decade, producing 2.6 million Higgs *** the SR power to 50 MW per beam expands the CEPC\'s capability togenerate 4.3 million Higgs bosons, facilitating precise measurements of Higgscoupling at sub-percent levels, exceeding the precision expected from theHL-LHC by an order of magnitude. This Technical Design Report (TDR) follows thePreliminary Conceptual Design Report (Pre-CDR, 2015) and the Conceptual DesignReport (CDR, 2018), comprehensively detailing the machine\'s layout andperformance, physical design and analysis, technical systems design, R&D andprototyping efforts, and associated civil engineering aspects. Additionally, itincludes a cost estimate and a preliminary construction timeline, establishinga framework for forthcoming engineering design phase and site selectionprocedures. Construction is anticipated to begin around 2027-2028, pendinggovernment approval, with an estimated duration of 8 years. The commencement ofexperiments could potentially initiate in the mid-2030s. © 2023, CC BY-NC-SA.

关键词： Synchrotron radiation

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某铁路线崩塌落石危险性评估与防护措施研究

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路基工程 2022年第2期 189-194页

作者：张旭文韩剑侠范刚张文超陈蜀闽周家文四川大学水利水电学院成都610065 西藏自治区地质矿产勘查开发局第二地质大队拉萨850000 中国铁路成都局集团有限公司成都610082

采用三维激光扫描技术建立高精度地形模型,运用Rocpro3D软件对某铁路线某点位;3危岩区滚石影响范围及防治措施进行模拟研究。结果表明:现有防护措施下,落石滚落过程中存在明显的归槽现象,公路处滚石灾害等级为高和非常高,下部铁路处灾... 详细信息

采用三维激光扫描技术建立高精度地形模型,运用Rocpro3D软件对某铁路线某点位;3危岩区滚石影响范围及防治措施进行模拟研究。结果表明:现有防护措施下,落石滚落过程中存在明显的归槽现象,公路处滚石灾害等级为高和非常高,下部铁路处灾害等级为中等和高,受滚石威胁较大;在坡脚处补充三道被动防护网后,显著降低了落石滚落至铁路路基的概率。

关键词：崩塌落石三维仿真模拟运动特征运动速度弹跳高度运动动能危险性评估被动防护网

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