检索结果-内蒙古大学图书馆

Protective effects of ischemic postconditioning compared with gradual reperfusion or preconditioning

JOURNAL OF NEUROSCIENCE RESEARCH 2008年第11期86卷 2505-2511页

作者： Gao, xuwen Ren, Chuancheng zhao, Heng Stanford Univ Sch Med Dept Neurosurg Stanford CA 94305 USA Stanford Univ Stanford Stroke Ctr Stanford CA 94305 USA Fudon Univ Shanghai Med Coll Shanghai Hosp 5 Dept Neurol Shanghai Peoples R China

We examined the temporal factors of postconditioning, assessed whether gradual reperfusion reduces infarcts, and compared postconditioning's protection with that of both rapid and delayed preconditioning. Focal ischemia was generated by permanent occlusion of the left distal middle cerebral artery (dMCA) combined with 30 min of occlusion of both common carotid arteries (CCA) in rats. Postconditioning was performed by repetitive brief release and occlusion of CCA after 30 min of CCA occlusion. Gradual reperfusion was generated by controlled release of the bilateral CCA. We confirmed that postconditioning disrupted the early reperfusion but improved cerebral blood flow (CBF) thereafter. Postconditioning with three cycles, but not with 10 cycles, of 30 sec CCA release and 10 sec CCA occlusion (30s/10s) reduced infarction measured at 2 days after stroke. In addition, postconditioning with 10 cycles, but not with three cycles, of 10s/10s reduced infarction but it lost protection when initiated at 3 min after reperfusion. In addition, gradual reperfusion also reduced infarction. Moreover, both rapid and delayed preconditioning conducted 60 min and 3 days before stroke reduced infarct sizes. However, no additional protection was detected when postconditioning was combined with either rapid or delayed preconditioning. In conclusion, gradual reperfusion reduced infarction;postconditioning's protection depended on the number of cycles and duration of each cycle of reperfusion and occlusion and the onset time of postconditioning;postconditioning's protection was comparable to that of rapid preconditioning but not as robust as that of delayed preconditioning. (c) 2008 Wiley-Liss, Inc.

关键词： postconditioning preconditioning stroke cerebral ischemia focal ischemia

来源：评论

学校读者我要写书评

暂无评论

Enhancement　of　Supercontinuum　Spectrum　Generation　in　aDispersion-Decreasing　Fibre　with　a　Concave　Dispersion　Profile

引用

Chinese Physics Letters 2004年第6期21卷 1089-1092页

作者： xuwen-Cheng JINWei XUYong-zhao CUIHu LIUSong-Hao InstituteofQuantumElectronics SouthChinaNormalUniversityGuangzhou510631

A new approach is proposed to enhance supercontinuum (SC) spectrum generation in A dispersion-decreasing optical fibre with a new dispersion profile. The chromatic dispersion D(λ, z) is a concave function of wavelengths and has no zero-dispersion wavelengths over the whole or part of the fibre as D(λ, z) is positive. A flatter and much broader spectrum can be produced based on the scheme. The general criteria parameters are obtained for characterizing SC shapes in the optical fibres.

关键词： Optics quantum optics and lasers

来源：评论

学校读者我要写书评

暂无评论

血清I-FABP和CBG对新生儿坏死性小肠结肠炎需要选择手术治疗的预测价值

引用

江苏医药 2024年第6期50卷 577-581页

作者：杨福江胡博戴春娟马林赵绪稳王金虎杜晓斌天津市儿童医院(天津大学儿童医院)新生儿外科天津300074

目的探讨血清肠型脂肪酸结合蛋白(I-FABP)和β葡萄糖苷酶(CBG)对新生儿坏死性小肠结肠炎(NEC)需要选择手术治疗的预测价值。方法93例确诊为NEC的新生儿,根据患儿住院后是否进行手术治疗分为手术组(27例)和非手术组(66例)。比较两组患儿... 详细信息

目的探讨血清肠型脂肪酸结合蛋白(I-FABP)和β葡萄糖苷酶(CBG)对新生儿坏死性小肠结肠炎(NEC)需要选择手术治疗的预测价值。方法93例确诊为NEC的新生儿,根据患儿住院后是否进行手术治疗分为手术组(27例)和非手术组(66例)。比较两组患儿一般资料及确诊NEC时血清I-FABP、CBG水平。采用多因素logistic回归分析NEC患儿选择手术治疗的独立影响因素。分析血清I-FABP和CBG单独及联合检测对NEC患儿行手术治疗的预测价值。结果手术组血清I-FABP及CBG水平高于非手术组(P<0.05)。多因素logistic回归分析结果显示,确诊NEC时血清I-FABP及CBG水平升高是NEC患儿行手术治疗的独立危险因素(P<0.05)。血清I-FABP联合CBG检测预测NEC患儿行手术治疗的AUC为0.941[95%CI(0.888~0.993),P<0.01],相应的预测灵敏度和特异度分别为85.0%和94.0%。结论确诊NEC时的血清I-FABP和CBG水平有助于早期预测需行手术治疗的NEC患儿。

关键词：新生儿坏死性小肠结肠炎肠型脂肪酸结合蛋白 β葡萄糖苷酶

来源：评论

学校读者我要写书评

暂无评论

The Akt Pathway Is Involved in Rapid Ischemic Tolerance in Focal Ischemia in Rats

引用

TRANSLATIONAL STROKE RESEARCH 2010年第3期1卷 202-209页

作者： Gao, xuwen Zhang, Hanfeng Steinberg, Gary zhao, Heng Stanford Univ Sch Med Dept Neurosurg Stanford CA 94305 USA Stanford Univ Sch Med Stanford Stroke Ctr Stanford CA 94305 USA

Although the protective mechanisms of delayed ischemic preconditioning have received extensive studies, few have addressed the mechanisms associated with rapid ischemic preconditioning. We investigated whether ischemic tolerance induced by rapid preconditioning is regulated by the Akt survival signaling pathway. Stroke was generated by permanent occlusion of the left distal middle cerebral artery plus 30 min or 1 h occlusion of the bilateral common carotid artery (CCA) in male rats. Rapid preconditioning performed 1 h before stroke onset reduced infarct size by 69% in rats with 30 min CCA occlusion, but by only 19% with 1 h occlusion. After control ischemia with 30 min CCA occlusion, Western blot showed that P-Akt was transiently increased while Akt kinase assay showed that Akt activity was decreased. Although preconditioning did not change P-Akt levels at 1 and 5 h compared with control ischemia, it attenuated reduction in Akt activity at 5 h in the penumbra. However, preconditioning did not change the levels of P-PDK1, P-PTEN, and P-GSK3 beta in the Akt pathway, all of which were decreased after stroke. At last, the PI3K kinase inhibitor, LY294002, completely reversed the protection from ischemic preconditioning. In conclusion, Akt contributes to the protection of rapid preconditioning against stroke.

关键词： Rapid preconditioning Ischemic tolerance Cerebral ischemia Focal ischemia Neuroprotection Akt

来源：评论

学校读者我要写书评

暂无评论

Mechanistic investigations into synergistically enhanced radiative-charge-transfer in Au-Ag bimetallic nanoclusters (vol 56, pg 5665, 2020)

引用

CHEMICAL COMMUNICATIONS 2020年第48期56卷 6594-6594页

作者： Liu, Jianbo zhao, Rusong Wang, Xia Gao, xuwen Zou, Guizheng Qilu Univ Technol Key Lab Appl Technol Sophisticated Analyt Instrum Shandong Acad Sci Shandong Anal & Test Ctr Jinan 250353 Peoples R China Shandong Univ Sch Chem & Chem Engn Jinan 250100 Peoples R China

Synergetic effects in Au-Ag bimetallic nanoclusters (BNCs) more favorably enhanced electrochemical redox induced electrochemiluminescence (ECL) over photoexcitation induced photoluminescence (PL); this not only led to Au-Ag BNCs with enhanced bandgap-engineered ECL compared to Au NCs, but it also generated surface-defect related ECL to enhance the total ECL intensity.

关键词： Surface defects

来源：评论

学校读者我要写书评

暂无评论

The antiallergic activity of flavonoids extracted from Citri Reticulatae Pericarpium

引用

JOURNAL OF FOOD PROCESSING AND PRESERVATION 2018年第4期42卷 e13588-e13588页

作者： Shi, Xiaolei Niu, Liyan zhao, Lina Wang, Bo Jin, Yongri Li, xuwen Jilin Univ Dept Food Qual & Safety Coll Food Sci & Engn Changchun 130062 Jilin Peoples R China Jilin Univ Dept Analyt Chem Coll Chem Changchun 130012 Jilin Peoples R China

The fruits of Citrus are popular all over the world. It was reported that the extracts of fruits possessed antiallergic activities. In China, Citri Reticulatae Pericarpium (CRP) is a production of peels. In this study, flavonoids were extracted by solvent method, and enriched by polyamide. Then antiallergic activity of flavonoids was investigated in vivo and in vitro. Under optimal parameters, most abundant compounds of extracts were hesperidin and narirutin, their contents were 232.0325 and 98.7946 mg/g, respectively. In vitro, RBL-2H3 cell line was used to investigate the antiallergic activity. As the results shown, -hexosaminidase release of antigen-induced degranulation was decreased by flavonoids. An ovalbumin-induced allergic asthmatic model was used to test the activity of the flavonoids in vivo. After treated with different concentrations of flavonoids, the levels of IgE, IL-4, and IL-13 decreased significantly. These findings provide evidence that flavonoids extracted from CRP have potential using in antiallergic therapeutic area. Practical applicationsOranges are popular all over the world as fruit, besides a little percent of peels are applied as traditional medicine in China, the others are thrown away as rubbish. To explore the new way to extend the application of peels, we extracted the total flavonoids from Citri Reticulatae Pericarpium (CRP) and evaluated the antiallergic activity of it. Fortunately, the total flavonoids have antiallergic activity in vitro and vivo. The findings provide evidence that extracts from CRP have potential using in antiallergic therapeutic area. It can also afford a theoretical basis for the new application of orange peel.

关键词： Citrus fruits

来源：评论

学校读者我要写书评

暂无评论

Strongly prolonged hydroxyl radical production for Fenton-like reactions: The golden touch of Cu

引用

SEPARATION AND PURIFICATION TECHNOLOGY 2019年 213卷 500-506页

作者： Da, xuwen Ji, Hongwei zhao, Zhenwen Lan, Rongshan Li, Tuo Ma, Jiahai Univ Chinese Acad Sci Sch Chem Sci Beijing 100049 Peoples R China Chinese Acad Sci Inst Chem Key Lab Photochem Beijing 100190 Peoples R China Chinese Acad Sci Beijing Mass Spectrum Ctr Inst Chem Beijing 100190 Peoples R China

Hydroxyl radicals are believed as the most reactive species in the Fenton-like reactions and perform well at the beginning stage of the reaction due to very short lifetime. A reaction system with strongly prolonged hydroxyl radical lifetime is rarely reported. Adding Cu ions, an unreactive catalyst for hydrogen peroxide activation, the Fe/Cu/CDBQ/H2O2 system efficiently prolonged hydroxyl radical lifetime with two orders. This study found a strong, prolonged hydroxyl radical generation in a Fenton-like system using iron, copper ions and 2,5-dihydroxy-1,4-benzoquinone restricted in cyclodextrin (CDBQ). Meanwhile, rapid degradation and substantial mineralization of organics was achieved in this system. Further, the Cu ions could promote the efficiency of other Fenton-like system.

关键词： Hydroxyl radical Fenton reaction Copper ion

来源：评论

学校读者我要写书评

暂无评论

A general method for instantaneous undeformed chip thickness calculation in five-axis milling based on Boolean operations

引用

INTERNATIONAL JOURNAL OF ADVANCED MANUFACTURING TECHNOLOGY 2021年第7-8期116卷 2325-2334页

作者： Li, Guochao Liu, Yunlong zhao, Donghao Dai, Lei Zhou, Honggen Jing, xuwen Jiangsu Univ Sci & Technol Sch Mech Engn Zhenjiang 212003 Jiangsu Peoples R China Jiangsu Univ Sci & Technol Jiangsu Prov Key Lab Adv Mfg Marine Mech Equipmen Zhenjiang 212003 Jiangsu Peoples R China

Instantaneous undeformed chip thickness (IUCT) plays a critical role in optimizing and monitoring of five-axis milling processes, as it determines machining precision and tool life by affecting cutting forces. Analytical and numerical methods have been widely used for IUCT calculation. However, these methods have some deficiencies, such as solving the unsolvable transcendental equations, modeling the complex cutting edge trajectory, and poor adaptability for five-axis milling. Therefore, a Boolean method which consists of subtraction and intersection operations is developed. First, the blank for the current cutting edge is obtained by the Boolean subtraction operation between the workpiece and the swept volume that produced by the front cutting edges. Second, the Boolean intersection operation is executed between the blank and the auxiliary edge entity (AEE) that corresponding to the tool edge. Then, the IUCT of each cutting edge or each cutting point can be deduced based on the Boolean result with the known blank geometry, tool geometry, tool path, and machining parameters. The method is verified by milling force experiments. It is an efficient, accurate, and general method because it does not need to establish complex mathematical or numerical models. The calculated IUCT will promote the optimizing and monitoring of five-axis milling processes.

关键词： Chip thickness Boolean operation Five-axis milling Milling force

来源：评论

学校读者我要写书评

暂无评论

Optimal Clearing Model of Centralized Market Considering Path Constraints 1

Optimal Clearing Model of Centralized Market Considering Pat...

引用

International Symposium on Energy Environment and Green Development (EEGD)

作者： Zheng, zhao Chen, Kening Jiang, Yu Liu, xuwen State Grid Energy Res Inst Beijing Peoples R China State Grid JiangSu Elect Power Co Ltd Nanjing Jiangsu Peoples R China

China's electricity market is now still in the mode of "Unified market and two-tier operation" including provincial and inter-provincial market. The inter-provincial market is divided into the medium and long-term market and spot market. This study takes the inter provincial spot market as the research object, and proposes a unified optimization clearing algorithm for inter provincial spot market considering path constraints. The proposed method is able to handle AC-DC hybrid electricity network, and sort and determine the trading pairs using power flow tracing algorithm. The power market software PLEXOS and practical market data are used to simulate the proposed model, and the results show the accuracy and effectiveness.

关键词： Power markets

来源：评论

学校读者我要写书评

暂无评论

Stereo matching algorithm of Color Image Based on Weber's law and Census 10

Stereo matching algorithm of Color Image Based on Weber's la...

引用

10th International Conference on Intelligent Information Hiding and Multimedia Signal Processing (IIH-MSP)

作者： Wu, Qiang zhao, Xiangnan Li, xuwen Beijing Univ Technol Coll Elect Informat & Control Engn Beijing Peoples R China Beijing Univ Technol Coll Life Sci & Bioengn Beijing Peoples R China

ISBN: (纸本)9781479953905

The algorithm presented here is used on unmanned aerial vehicles system. In 2013,*** proposed a matching cost computation model(or function), This matching cost model combined three kinds of constraints, the cost function is formulated by combining three individual costs: a cost computed on an extended census transformation of the images;the absolute difference cost, taking into account information from colour channels;and a cost based on the principal image derivatives. Experiments show that the cost function is excellent performance in similar estimates. Apply it to the stereo matching of ancient buildings, it is favorable for practical. However, this experiment, in color mutated region, leaded to blurred border. Therefore, our proposed method added color space structural information, which based on HVS Weber's law, to the cost function. we use the differential excitation of WLD reflects the structure of color space. This robust cost measures can reduce percent of bad pixels in mutated color region. The proposed method use color image, which is used after epipolar line rectification.

关键词： The stereo matching of color image Census Weber's law

来源：评论

学校读者我要写书评

暂无评论

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

请选择保存的检索档案：

请选择收藏分类：

通借通还

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：