检索结果-内蒙古大学图书馆

Memristive Artificial Synapses for Neuromorphic Computing

Nano-Micro Letters 2021年第5期13卷 218-245页

作者： Wen huang xuwen Xia Chen Zhu Parker Steichen Weidong Quan Weiwei Mao Jianping Yang Liang Chu Xing’ao Li New Energy Technology Engineering Laboratory of Jiangsu Province and School of Science Nanjing University of Posts and Telecommunications(NJUPT)Nanjing 210023People’s Republic of China Key Laboratory for Organic Electronics and Information Displays and Institute of Advanced Materials Jiangsu National Synergistic Innovation Center for Advanced MaterialsSchool of Materials Science and EngineeringNanjing University of Posts and Telecommunications(NUPT)9 Wenyuan RoadNanjing 210023People’s Republic of China College of Electronic and Optical Engineering and College of Microelectronics Nanjing University of Posts and Telecommunications(NJUPT)Nanjing 210023People’s Republic of China Department of Materials Science and Engineering University of WashingtonSeattleWA 98195‑2120USA

Neuromorphic computing simulates the operation of biological brain function for information processing and can potentially solve the bottleneck of the von Neumann *** computing is realized based on memristive hardware neural networks in which synaptic devices that mimic biological synapses of the brain are the primary *** synaptic functions with these devices is critical in neuromorphic *** the last decade,electrical and optical signals have been incorporated into the synaptic devices and promoted the simulation of various synaptic *** this review,these devices are discussed by categorizing them into electrically stimulated,optically stimulated,and photoelectric synergetic synaptic devices based on stimulation of electrical and optical *** working mechanisms of the devices are analyzed in *** is followed by a discussion of the progress in mimicking synaptic *** addition,existing application scenarios of various synaptic devices are ***,the performances and future development of the synaptic devices that could be significant for building efficient neuromorphic systems are prospected.

关键词： Synaptic devices Neuromorphic computing Electrical pulses Optical pulses Photoelectric synergetic effects

来源：评论

学校读者我要写书评

暂无评论

Synergistic effects of asphaltenes, kaolinite, and water chemistry on oil-water emulsion stability

引用

Separation and Purification Technology 2025年 372卷

作者： Zhou, Qi Sun, Yongxiang Ma, Hongtao Song, Xuguang huang, Pan Mao, Xiaohui Peng, xuwen Zeng, Hongbo Department of Chemical and Materials Engineering University of Alberta EdmontonABT6G 1H9 Canada College of Materials Science and Engineering Donghua University 2999 North Renmin Road Shanghai201620 China Department of Chemical Engineering Tsinghua University Beijing100084 China

Effective treatment of emulsions formed during the bitumen extraction process is crucial for oil–water separation and subsequent processing. However, it remains a challenge in the oil sands industry due to the complex mixture of solids, water, and bitumen. Asphaltenes in bitumen and fine clay minerals in solids can significantly adsorb at interfaces and contribute to emulsion stability, which makes oil–water separation difficult. Very limited attention has been paid to the synergistic effects of asphaltenes, solids, and complex water chemistry involved in the bitumen extraction process. This study characterized asphaltenes and kaolinite, with kaolinite acting as a representative clay mineral in the experiments. The synergistic effects of asphaltenes and kaolinite fine particles on emulsion stability and interfacial properties were systematically investigated through demulsification bottle tests, zeta potential measurements, dynamic interfacial tension, and dilatational rheology analyses. The results suggest that kaolinite fine particles substantially enhance the stability of asphaltene-stabilized emulsions. Meanwhile, metal salts, especially divalent salts such as MgCl2 and CaCl2 in water, can further contribute to the stability of both asphaltene-stabilized emulsions and emulsions co-stabilized by asphaltenes and kaolinite. Computational insights from density functional theory and ab initio molecular dynamics elucidate the molecular-level interactions between asphaltenes, kaolinite, and metal cations. This work has improved the understanding of emulsion stability mechanisms posed by asphaltenes, clay minerals, and complex water chemistries in bitumen extraction and crude oil production. The results contribute to advancing separation and purification technologies critical to the oil sands industry. © 2025 The Authors

关键词： Asphalt mixtures

来源：评论

学校读者我要写书评

暂无评论

Mesoporous Palladium-Boron-Sulfur Alloy Nanospheres for Efficient Hydrogen Evolution

引用

INORGANIC CHEMISTRY 2021年第7期60卷 4380-4384页

作者： Guo, xuwen Chen, Zhichao huang, Yanping Lv, Hao Wang, Yaru Sun, Lizhi Song, Kai Liu, Ben Nanjing Normal Univ Jiangsu Collaborat Innovat Ctr Biomed Funct Mat Sch Chem & Mat Sci Jiangsu Key Lab New Power Batteries Nanjing 210023 Peoples R China Shenzhen RELX Technol Co Ltd Shenzhen 518108 Peoples R China Sichuan Univ Coll Chem Chengdu 610064 Peoples R China Changchun Normal Univ Sch Life Sci Changchun 130032 Peoples R China Sichuan Univ Sch Chem Engn Ctr Engn Expt Teaching Chengdu 610065 Peoples R China

Ternary noble metal-metalloid-nonmetal PdBS alloy mesoporous nanospheres (MSs) with three-dimensional central-radial pore channels were prepared for an electrocatalytic hydrogen evolution reaction. The synthesis was performed via precise control in the reduction and nucleation growth of ternary PdBS alloy MSs along confined cylinder mesophases assembled by amphiphilic dioctadecyldimethylammonium chloride. The resultant PdBS alloy MSs disclosed a remarkably improved electrocatalytic performance due to their structural and compositional synergies. This finding extended our knowledge on the rational design and targeted synthesis of novel noble metal-metalloid-nonmetal alloys with desired structures and morphologies for catalysis and other applications.

关键词： Palladium Alloys Genetics Evolution reactions Transmission electron microscopy

来源：评论

学校读者我要写书评

暂无评论

Delays in routine childhood vaccinations and their relationship with parental vaccine hesitancy: a cross-sectional study in Wuxi, China

引用

EXPERT REVIEW OF VACCINES 2022年第1期21卷 135-143页

作者： Wang, Qiang Xiu, Shixin Yang, Liuqing Han, Ying huang, Jinxin Cui, Tingting Shi, Naiyang Liu, Minqi Wang, xuwen Lu, Bing Jin, Hui Lin, Leesa Southeast Univ Sch Publ Hlth Dept Epidemiol & Hlth Stat 87 Dingjiaqiao Nanjing 210009 Peoples R China Southeast Univ Sch Publ Hlth Key Lab Environm Med Engn Minist Educ Nanjing Peoples R China Wuxi Ctr Dis Control & Prevent Dept Immunizat Planning Wuxi Jiangsu Peoples R China London Sch Hyg & Trop Med Dept Infect Dis Epidemiol London England Hong Kong Sci Pk Lab Data Discovery Hlth D24H Hong Kong Peoples R China

Objectives This study aimed to examine childhood vaccination delay, explore the association between vaccination delay and parental vaccine hesitancy, and assess childhood vaccination delays during the coronavirus disease (COVID)-19 pandemic in China. Methods This cross-sectional survey was conducted in Wuxi City. Participants were recruited from local vaccination clinics. Questionnaires were used to collect information about socio-demographics, vaccine hesitancy, and immunization clinic evaluations. Vaccination records were obtained from the Jiangsu Information Management System of Vaccination Cases. Results Overall, 2728 participants were included. The coverage for seven category A vaccines (Expanded Program on Immunization (EPI)) was more than 95% at 24 months. The proportion of children vaccinated in a timely manner was the highest for the first dose of the hepatitis B vaccine (91.6%) and the lowest for the Bacillus-Calmette-Guerin vaccine (44.6%). More than 50% of the planned vaccinations were delayed in February and March 2020. The Vaccine Hesitancy Scale scores were not associated with vaccination delay (P = 0.842). Children's vaccination delays were negatively associated with parents who reported convenient access to clinics and satisfaction with immunization services (P = 0.020, P = 0.045). Conclusions EPI is highly successful in China. Despite vaccination delays due to the COVID-19 pandemic, coverage was recovered after lockdown restrictions were eased.

关键词： Childhood vaccination delay timeliness vaccine hesitancy COVID-19 pandemic

来源：评论

学校读者我要写书评

暂无评论

Hierarchical flower-like manganese oxide/polystyrene with enhanced oxidase-mimicking performance for sensitive colorimetric detection of glutathione

引用

MICROCHIMICA ACTA 2022年第2期189卷 63-63页

作者： Liu, Ying Yan, Jianghong Sun, Zhiheng huang, Yu Li, xuwen Jin, Yongri Jilin Univ Coll Chem 2699 Qianjin Rd Changchun 130012 Peoples R China Jilin Prov Acad Tradit Chinese Med Clin Hosp 1 Changchun 130021 Peoples R China

Glutathione (GSH) is an important antioxidant and free radical scavenger that converts harmful toxins into harmless substances and excretes them out of the body. In this paper, 3D hierarchical flower-like nanozyme named MnO2/PS (polystyrene) was successfully prepared by template method for the first time. After the systematical studies, MnO2/PS nanozyme was evaluated to possess favorable oxidase activity and direct 3,3',5,5'-tetramethylbenzidine (TMB) catalytic ability in the near-neutral environment at room temperature. With the addition of different concentrations of GSH, oxidized TMB can be reduced to TMB with the whole process from blue to nearly colorless be observed by naked eyes. In addition, there is a good linear relationship in the range 1-50 mu M and a detection limit of 0.08 mu M. The method proposed can be successfully applied to the detection of reduced GSH in tablets and injections with good selectivity and high sensitivity. The analysis results exhibited good consistency with the results obtained by HPLC.

关键词： Oxidase-like activity Manganese oxide Flower-like nanozyme GSH detection Colorimetric sensor

来源：评论

学校读者我要写书评

暂无评论

Comparison of health-related quality of life measures in asthma-COPD overlap

引用

CHRONIC RESPIRATORY DISEASE 2023年 20卷

作者： Liu, Meishan Yang, xuwen Wang, Ying Lu, Yong Liang, Lirong Zhang, Hong huang, Kewu Capital Med Univ Beijing Inst Resp Med Dept Resp & Crit Care Med Beijing Peoples R China Capital Med Univ Beijing Chao Yang Hosp Beijing Peoples R China Capital Med Univ Beijing Inst Resp Med Dept Clin Epidemiol Beijing Peoples R China Capital Med Univ Beijing Inst Resp Med Dept Resp & Crit Care Med 8 Gongti South Rd Beijing 100020 Peoples R China Capital Med Univ Beijing Chao Yang Hosp 8 Gongti South Rd Beijing 100020 Peoples R China

Objective: The Asthma Quality of Life Questionnaire (AQLQ) and COPD assessment test (CAT) are used to assess the health status of asthma and chronic obstructive pulmonary disease (COPD), respectively. However, whether these questionnaires are appropriate in patients with asthma-COPD overlap (ACO) has not been reported. This study aimed to evaluate the performance of the AQLQ and CAT in subjects with ***: Subjects were enrolled from two previously described observational studies in Beijing, China. ACO was defined by a consensus definition from a roundtable discussion. All subjects completed the AQLQ, CAT, St George's Respiratory Questionnaire (SGRQ), pulmonary function tests, and the Asthma Control Questionnaire (ACQ)-5. Cross-sectional construct validity was evaluated by correlating the AQLQ and CAT with SGRQ score and other measures of asthma and COPD ***: 147 subjects with ACO were recruited. There were floor effects on non-respiratory components of the CAT, and ceiling effects on emotion domains of the AQLQ. Both questionnaires were significantly correlated with ACQ-5 score but were not correlated with FEV1% predicted or FVC% predicted. The AQLQ and CAT were strongly correlated with SGRQ score (r = -0.657 and r = 0.623, respectively). Multivariable linear regression analysis showed that the AQLQ (standardized beta-coefficient = -0.449, p < .001) had a stronger association with SGRQ score compared with CAT (standardized beta-coefficient = 0.211, p = .023).Discussion: The AQLQ and CAT were both valid for assessing the health-related quality of life in subjects with ACO, but the AQLQ performed better than CAT.

关键词： asthma-chronic obstructive pulmonary disease overlap health-related quality of life chronic obstructive pulmonary disease assessment test asthma quality of life questionnaire validity

来源：评论

学校读者我要写书评

暂无评论

Structural brain characteristics and gene co-expression analysis: A study with outcome label from normal cognition to mild cognitive impairment

引用

NEUROBIOLOGY OF LEARNING AND MEMORY 2022年第0期191卷 000-000页

作者： Cai, Suping Yang, Fan Wang, xuwen Wu, Sijia huang, Liyu Xidian Univ Sch Life Sci & Technol Xian 710071 Shaanxi Peoples R China

Background: Longitudinal studies reported that some elderly people with normal cognition (NC) converted to mild cognitive impairment (MCI), and some remained normal state (NC_S). The underlying factor for this difference conversion of NC is worthy of exploration Methods: Eighty-three NC participants were tracked for eight years. Thirty participants transitioned from NC to MCI (NC_MCI). The remaining 53 participants retained an NC_S. The structural brain features and genetic expression of the 83 NC participants were obtained. We applied weighted gene co-expression network analysis (WGCNA) to inquire into the co-expression network of those. Mediator effect analysis of regulatory roles was conducted to inquire into the associations between brain measures, expression values, and clinical scores. Results: The main results are: 1) 20 brain features and 740 gene expression had significant differences between the two groups, 2) one module including 187 genes had the most correlation with cortical thickness of left superior temporal sulcus (***), 3) NFKBIA and RARA genes were the top two genes that made the greatest contribution to *** thickness, and 4) mediating effect was found between the *** thickness, the NFKBIA and RARA expression levels, and clinical scores. Conclusion: Our results provide a theoretical foundation based on gene expression and brain imaging for the factors of NC with different outcomes.

关键词： Conversion WGCNA analysis T1-weighted MRI images NFKBIA and RARA genetic expression Mediator effect

来源：评论

学校读者我要写书评

暂无评论

Organic metal matrix Mil-88a nano-enzyme for joint repair in the osteoarthritis mouse model

引用

FRONTIERS IN BIOENGINEERING AND BIOTECHNOLOGY 2023年 11卷 1164942页

作者： Hu, Hao huang, Xu Dai, Yankun Zhu, Kairun Ye, xuwen Meng, Shengdong Zhang, Qing Xie, Xueguan Huaian Second Peoples Hosp Huaian Peoples R China

Introduction: In this paper we tried to conduct a novel nanomaterial strategy to overcome osteoarthritis (OA) in a mouse model. Methods: In this regard, after synthesizing the Mil-88a nanozyme, as a certain Fe-MOF, its toxic effects were detected by CCK-8 method and live-dead staining. The OA model of mouse was constructed, and paraffin sections of joints were taken for histological evaluation. In addition, immunofluorescence and immunohistochemistry were used to identify the OA progression and OARSI was used to evaluate the OA grades. We observed that Mil-88a could be easily synthesized and has high biocompatibility. Results: We observed that Mil-88a could significantly promote the expression of OA anabolism-related genes such as Col2 and also significantly inhibit the expression of OA catabolism-related genes MMP13. Besides, we observed better OARSI score in animals treated with Mil-88a nano-enzyme loading on organic metal matrix. Discussion: Overall, Mil-88a nano-enzyme could be used as a novel strategy to treat OA.

关键词： nano-enzyme osteoarthritis mouse model Mil-88a organic metal

来源：评论

学校读者我要写书评

暂无评论

Multi-scale Feature Fusion Extraction Structure for the Leather Defect Detection Algorithm

Multi-scale Feature Fusion Extraction Structure for the Leat...

引用

Pattern Recognition and Artificial Intelligence (PRAI), International Conference on

作者： xuwen He Hao Li Zihan huang Xiaorui Xiong Yifan Liu Yuting Yao School of Mathematics and Computer Science Wuhan Polytechnic University Wuhan China

Detection of surface defects using computer vision is a pivotal technology for achieving intelligent manufacturing. Leather products are one of the most widely traded goods in the world, and automatic identification, localization, and detection of surface defects in leather are indispensable for achieving intelligent manufacturing of leather products. This research paper proposes FG-DETR, a multi-scale feature fusion extraction structure for small target detection algorithms. Given the recent success of deep learning methods in various related fields and that certain defects and flaws in leather pictures in our dataset are relatively small. FG-DETR is based on DETR with some improvements as follows, Initially, DETR's ResNet50 network performs feature extraction on the original image and produces four scales of feature maps. Second, we apply a modified Feature Pyramid Network (FPN) to downsample and upsample the four scales of feature maps, followed by the fusion and output of a single feature map. A Gaussian kernel and output then process the fused feature maps as the final feature maps. Finally, the feature maps are merged with the position encoding information and combined into the Transformer encoder-decoder architecture, resulting in the detection outcomes through the Position-wise Feed-Forward Networks (FFN). In our leather dataset, the FG-DETR model is more effective in detecting small targets than DETR, as our leather images are large, and the original DETR is nearly ineffective for images with relatively small defects. The average detection accuracy of medium and large targets also improved, with a 7.6 percentage point improvement at AP50. The experimental findings demonstrate that the multi-scale feature fusion extraction structure significantly enhances the detection accuracy of DETR.

关键词：

来源：评论

学校读者我要写书评

暂无评论

Development of a Synthesis Process for a Novel HCV NS5A Inhibitor, Emitasvir

引用

ORGANIC PROCESS RESEARCH & DEVELOPMENT 2021年第4期25卷 838-848页

作者： Xie, Hongming Liu, Haiwang Zhang, Yingjun huang, Enhuo Feng, Yahui Xiang, xuwen Fang, Qinghong Peng, Zhihong Dong, Wanrong An, Delie Hunan Univ Coll Chem & Chem Engn State Key Lab Chemo Biosensing & Chemometr Changsha 410082 Hunan Peoples R China Sunshine Lake Pharma Co Ltd State Key Lab Antiinfect Drug Dev 2015DQ780357 Dongguan 523871 Peoples R China HEC Pharm Grp HEC Res & Dev Ctr Dongguan 523871 Peoples R China

A new approach to the synthesis of Emitasvir (DAG181), a small molecule hepatitis C virus (HCV) nonstructural protein 5A (NS5A) inhibitor, is described. Enantioselective enzymatic desymmetrization with hydrolases in the synthetical approach can significantly avoid the loss of chiral raw materials in the resolution process. The synthesis route is further optimized and scaled-up to establish a new process that is applied to the preparation of kilogram scales of target active pharmaceutical ingredients (APIs). Compared with our initial process, the overall yield of target API was dramatically improved from 17 to 40%.

关键词： hepatitis C virus inhibitor Emitasvir enantioselective synthesis process development

来源：评论

学校读者我要写书评

暂无评论

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

请选择保存的检索档案：

请选择收藏分类：

通借通还

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：