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RETRACTED: Urban Management in the Dynamic Relationship between the Occurrence of Environmental Pollution Accidents and Economic Development in China (Retracted Article)

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JOURNAL OF ENVIRONMENTAL AND PUBLIC HEALTH 2022年第1期2022卷

作者： Cong, xuwen Wang, Huaixing huang, Jingmei Changchun Univ Sch Adm Changchun 130022 Jilin Peoples R China Northeast Normal Univ Sch Polit & Law Changchun 130024 Jilin Peoples R China

After the reform and opening up, China has developed into a world factory due to the bias of Chinese policies, the need for urban development, and the limitations of science and technology. As a world factory, on the one hand, it expanded the scale of China's economy, raised the level of science and technology, and improved the standard of people's daily life. On the other hand, China's technology level was backward at the beginning of the reform and opening-up period, and the world countries in a competitive relationship could not give China a high-end technology level. Most of the developed countries only transferred their rough industries to China, which led to the "three highs and one low" pattern of China's economic development. The efficiency of resource utilization is very low, which not only wastes resources but also causes great deterioration of the environment. Based on China's environmental development problems, this article summarizes and analyses the relationship between economic development and environmental pollution through the perspective of EKC curve research. Then, using the data of economic growth target published by government work report of 230 prefecture-level cities from 2004 to 2014 collected by hand, the constraint of economic growth target is described from three dimensions. In particular, the study of economic growth target constraints is extended in terms of the portrayal of the characteristics of soft and hard constraints of economic growth targets. Finally, combining with the normative research method, feasible countermeasures are proposed for developed cities as well as less developed cities, providing new insights for the coordinated development of the urban environment and economy in China.

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Prediction of Subsequent Vertebral Fracture After Acute Osteoporotic Fractures from Clinical and Paraspinal Muscle Features

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CALCIFIED TISSUE INTERNATIONAL 2024年第6期114卷 614-624页

作者： Xiong, Yuchao Zhang, Cici Chen, Xiaopei Wu, Li Liang, Shaohua Zhang, Ye huang, Junbing Guo, Wei Zeng, xuwen Xu, Fan Jinan Univ Guangzhou Red Cross Hosp Dept Radiol Guangzhou Peoples R China

To construct a nomogram based on clinical factors and paraspinal muscle features to predict vertebral fractures occurring after acute osteoporotic vertebral compression fracture (OVCF). We retrospectively enrolled 307 patients with acute OVCF between January 2013 and August 2022, and performed magnetic resonance imaging of the L3/4 and L4/5 intervertebral discs (IVDs) to estimate the cross-sectional area (CSA) and degree of fatty infiltration (FI) of the paraspinal muscles. We also collected clinical and radiographic data. We used univariable and multivariable Cox proportional hazards models to identify factors that should be included in the predictive nomogram. Post-OVCF vertebral fracture occurred within 3, 12, and 24 months in 33, 69, and 98 out of the 307 patients (10.8%, 22.5%, and 31.9%, respectively). Multivariate analysis revealed that this event was associated with percutaneous vertebroplasty treatment, higher FI at the L3/4 IVD levels of the psoas muscle, and lower relative CSA of functional muscle at the L4/5 IVD levels of the multifidus muscle. Area under the curve values for subsequent vertebral fracture at 3, 12, and 24 months were 0.711, 0.724, and 0.737, respectively, indicating remarkable accuracy of the nomogram. We developed a model for predicting post-OVCF vertebral fracture from diagnostic information about prescribed treatment, FI at the L3/4 IVD levels of the psoas muscle, and relative CSA of functional muscle at the L4/5 IVD levels of the multifidus muscle. This model could facilitate personalized predictions and preventive strategies.

关键词： Osteoporosis Compression fracture Paraspinal muscles Fat infiltration Nomograms

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Step-Controlled Povarov-Type Reaction with 1,2-Dihydroquinolines as Precursors of Dienophiles: Direct Synthesis of Spirocyclic Bi-tetrahydroquinolines and Functionalized 1,2-Dihydroquinolines

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ORGANIC LETTERS 2017年第1期19卷 58-61页

作者： Ren, xuwen Li, Guangxun huang, Jin Wang, Weidong Zhang, Yongpo Xing, Guomin Gao, Chunyan Zhao, Gang Zhao, Jinzhong Tang, Zhuo Shanxi Agr Univ Taigu Coll Art & Sci Jinzhong 030800 Shanxi Peoples R China Chinese Acad Sci Chengdu Inst Biol Nat Prod Res Ctr Chengdu 610041 Sichuan Peoples R China Sichuan Univ Coll Chem Engn Chengdu 610041 Sichuan Peoples R China

A novel Povarov-type reaction for straightforward synthesis of novel spiro bi-tetrahydroquinolines with readily available 1,2-DHQs (1,2-dihydroquinolines) and aromatic imines was developed. The reaction could be selectively stopped at the first stage under a Bronsted acid catalyst to afford the corresponding functionalized 1,2-DHQs conveniently.

关键词： QUINOLINE synthesis CHEMICAL reactions CHEMICAL precursors DIENOPHILES SPIRO compounds synthesis

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Association between structural brain features and gene expression by weighted gene co-expression network analysis in conversion from MCI to AD

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BEHAVIOURAL BRAIN RESEARCH 2021年第0期410卷 113330-113330页

作者： Wang, xuwen huang, Kexin Yang, Fan Chen, Dihun Cai, Suping huang, Liyu Xidian Univ Sch Life Sci & Technol Xian 710071 Shaanxi Peoples R China

Alzheimer's disease (AD) is a neurodegenerative disease. Mild cognitive impairment (MCI) represents a state of cognitive function between normal cognition and dementia. Longitudinal studies showed that some MCI patients remained in a state of MCI, and some developed AD. The reason for these different conversions from MCI remains to be investigated. 180 MCI participants were followed for eight years. 143 MCI patients maintained the MCI state (MCI_S), and the remaining thirty-seven MCI patients were re-evaluated as having AD (MCI_AD). We obtained 1,036 structural brain characteristics and 15,481 gene expression values from the 180 MCI participants and applied weighted gene co-expression network analysis (WGCNA) to explore the relationship between structural brain features and gene expression. Regulating mediator effect analysis was employed to explore the relationships among gene expression, brain region measurements and clinical phenotypes. We found that 60 genes from the MCI_S group and 18 genes from the MCI_AD group respectively had the most significant correlations with left paracentral lobule and sulcus (***) and right subparietal sulcus (***) thickness;CTCF, UQCR11 and WDR5B were the mutual genes between the two groups. The expression of CTCF gene and clinical score are completely mediated by *** thickness, and the UQCR11 and WDR5B gene expression levels significantly regulate the mediating effect pathway. In conclusion, the factors affecting the different conversions from MCI are closely related to *** thickness and the CTCF, UQCR11 and WDR5B gene expression levels. Our results add a theoretical foundation of imaging genetics for conversion from MCI to AD.

关键词： Weighted gene co-expression network analysis Structural magnetic resonance imaging CTCF UQCR11 and WDR5B genetic expression Regulatory mediator effect analysis Conversion

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Delays in routine childhood vaccinations and their relationship with parental vaccine hesitancy: a cross-sectional study in Wuxi, China

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EXPERT REVIEW OF VACCINES 2022年第1期21卷 135-143页

作者： Wang, Qiang Xiu, Shixin Yang, Liuqing Han, Ying huang, Jinxin Cui, Tingting Shi, Naiyang Liu, Minqi Wang, xuwen Lu, Bing Jin, Hui Lin, Leesa Southeast Univ Sch Publ Hlth Dept Epidemiol & Hlth Stat 87 Dingjiaqiao Nanjing 210009 Peoples R China Southeast Univ Sch Publ Hlth Key Lab Environm Med Engn Minist Educ Nanjing Peoples R China Wuxi Ctr Dis Control & Prevent Dept Immunizat Planning Wuxi Jiangsu Peoples R China London Sch Hyg & Trop Med Dept Infect Dis Epidemiol London England Hong Kong Sci Pk Lab Data Discovery Hlth D24H Hong Kong Peoples R China

Objectives This study aimed to examine childhood vaccination delay, explore the association between vaccination delay and parental vaccine hesitancy, and assess childhood vaccination delays during the coronavirus disease (COVID)-19 pandemic in China. Methods This cross-sectional survey was conducted in Wuxi City. Participants were recruited from local vaccination clinics. Questionnaires were used to collect information about socio-demographics, vaccine hesitancy, and immunization clinic evaluations. Vaccination records were obtained from the Jiangsu Information Management System of Vaccination Cases. Results Overall, 2728 participants were included. The coverage for seven category A vaccines (Expanded Program on Immunization (EPI)) was more than 95% at 24 months. The proportion of children vaccinated in a timely manner was the highest for the first dose of the hepatitis B vaccine (91.6%) and the lowest for the Bacillus-Calmette-Guerin vaccine (44.6%). More than 50% of the planned vaccinations were delayed in February and March 2020. The Vaccine Hesitancy Scale scores were not associated with vaccination delay (P = 0.842). Children's vaccination delays were negatively associated with parents who reported convenient access to clinics and satisfaction with immunization services (P = 0.020, P = 0.045). Conclusions EPI is highly successful in China. Despite vaccination delays due to the COVID-19 pandemic, coverage was recovered after lockdown restrictions were eased.

关键词： Childhood vaccination delay timeliness vaccine hesitancy COVID-19 pandemic

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Hierarchical flower-like manganese oxide/polystyrene with enhanced oxidase-mimicking performance for sensitive colorimetric detection of glutathione

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MICROCHIMICA ACTA 2022年第2期189卷 63-63页

作者： Liu, Ying Yan, Jianghong Sun, Zhiheng huang, Yu Li, xuwen Jin, Yongri Jilin Univ Coll Chem 2699 Qianjin Rd Changchun 130012 Peoples R China Jilin Prov Acad Tradit Chinese Med Clin Hosp 1 Changchun 130021 Peoples R China

Glutathione (GSH) is an important antioxidant and free radical scavenger that converts harmful toxins into harmless substances and excretes them out of the body. In this paper, 3D hierarchical flower-like nanozyme named MnO2/PS (polystyrene) was successfully prepared by template method for the first time. After the systematical studies, MnO2/PS nanozyme was evaluated to possess favorable oxidase activity and direct 3,3',5,5'-tetramethylbenzidine (TMB) catalytic ability in the near-neutral environment at room temperature. With the addition of different concentrations of GSH, oxidized TMB can be reduced to TMB with the whole process from blue to nearly colorless be observed by naked eyes. In addition, there is a good linear relationship in the range 1-50 mu M and a detection limit of 0.08 mu M. The method proposed can be successfully applied to the detection of reduced GSH in tablets and injections with good selectivity and high sensitivity. The analysis results exhibited good consistency with the results obtained by HPLC.

关键词： Oxidase-like activity Manganese oxide Flower-like nanozyme GSH detection Colorimetric sensor

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Experimental Study on Noncoaxial Characteristics of Saturated Remolded Loess

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ADVANCES IN CIVIL ENGINEERING 2020年第1期2020卷

作者： Jiang, Xuemeng Niu, Haoshuang huang, Wenpeng Shang, xuwen Wang, Deng Changan Univ Key Lab Special Area Highway Engn Minist Educ Xian 710064 Peoples R China

In practical engineering, if the influence of noncoaxial stress and strain is not considered, part of soil deformation will be ignored, resulting in the structural design which is not safe enough. A series of undrained tests was performed on remolded loess specimens using a hollow cylinder apparatus to examine the coupling between principal stress magnitude and direction in these specimens. First, the elastic parameters of remolded loess were obtained, and these parameters were used as the basis for investigating the noncoaxiality of the soil body under principal stress axis rotation (PSAR). The effects of elastic strain, intermediate principal stress coefficient, and magnitude of the deviatoric stress on the noncoaxiality of remolded loess were also investigated. The results of these experiments show that remolded loess exhibits significant noncoaxial behavior during PSAR. The noncoaxiality angle of remolded loess cyclically fluctuates with increases in the principal stress angle. It was also observed that the noncoaxiality angle will be overestimated if the effects of elastic strain are overlooked. Reversals in the direction of PSAR cause dramatic changes in the noncoaxiality angle. Increases in the intermediate principal stress coefficient are accompanied by increases in the noncoaxiality angle, up to a certain degree;however, these changes do not affect the development of the noncoaxiality angle. In coupled rotational tests with a range of deviatoric stress amplitudes, it was observed that changes in the deviatoric stress amplitude will affect the development of the noncoaxiality angle;increases in the deviatoric stress amplitude cause the noncoaxiality angle versus principle stress angle plot to shift to the left gradually, thus accelerating the trends of the noncoaxiality angle. Increases in the cycle number also increase the noncoaxiality of remolded loess.

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Materiality, Experience and the Body: The Catholic Pilgrimage of Sheshan in Shanghai, China

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RELIGIONS 2023年第1期14卷 40页

作者： huang, Jianbo Zheng, xuwen Lee, Christine East China Normal Univ Inst Anthropol Minhang Campus Shanghai Peoples R China

This paper foregrounds the Turnerian experiences of pilgrims themselves, for whom pilgrimage is perhaps first and foremost the process of experiencing faith with their whole body and mind. At the Chinese Catholic pilgrimage site of Sheshan, located in western Shanghai, multiple meanings and possibilities are written onto the body of the pilgrim as it interacts with sacred materialities. In the process, the pilgrim materially orients themselves towards the transcendent other and to people and events throughout time. The boundary between subject and object is increasingly blurred in the pilgrim's imagination, and pilgrimage becomes a 'porous' mind-body experience for them. In the process, as pilgrims repeatedly physically enact doctrine and doctrinal texts in the course of pilgrimage-while simultaneously rooting them in their own personal lives-Sheshan is, through the concrete actions of worshippers layered up over time, continually being re-made as sacred.

关键词： Sheshan pilgrimage religious experience materiality body anthropology of experience

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Structural brain characteristics and gene co-expression analysis: A study with outcome label from normal cognition to mild cognitive impairment

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NEUROBIOLOGY OF LEARNING AND MEMORY 2022年第0期191卷 000-000页

作者： Cai, Suping Yang, Fan Wang, xuwen Wu, Sijia huang, Liyu Xidian Univ Sch Life Sci & Technol Xian 710071 Shaanxi Peoples R China

Background: Longitudinal studies reported that some elderly people with normal cognition (NC) converted to mild cognitive impairment (MCI), and some remained normal state (NC_S). The underlying factor for this difference conversion of NC is worthy of exploration Methods: Eighty-three NC participants were tracked for eight years. Thirty participants transitioned from NC to MCI (NC_MCI). The remaining 53 participants retained an NC_S. The structural brain features and genetic expression of the 83 NC participants were obtained. We applied weighted gene co-expression network analysis (WGCNA) to inquire into the co-expression network of those. Mediator effect analysis of regulatory roles was conducted to inquire into the associations between brain measures, expression values, and clinical scores. Results: The main results are: 1) 20 brain features and 740 gene expression had significant differences between the two groups, 2) one module including 187 genes had the most correlation with cortical thickness of left superior temporal sulcus (***), 3) NFKBIA and RARA genes were the top two genes that made the greatest contribution to *** thickness, and 4) mediating effect was found between the *** thickness, the NFKBIA and RARA expression levels, and clinical scores. Conclusion: Our results provide a theoretical foundation based on gene expression and brain imaging for the factors of NC with different outcomes.

关键词： Conversion WGCNA analysis T1-weighted MRI images NFKBIA and RARA genetic expression Mediator effect

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DRL-Based Dynamic Destroy Approaches for Agile-Satellite Mission Planning

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REMOTE SENSING 2023年第18期15卷 4503页

作者： huang, Wei Li, Zongwang He, Xiaohe Xiang, Junyan Du, Xu Liang, xuwen ShanghaiTech Univ Sch Informat Sci & Technol Shanghai 201210 Peoples R China Chinese Acad Sci Innovat Acad Microsatellites Shanghai 201306 Peoples R China Univ Chinese Acad Sci Beijing 100039 Peoples R China Henan Acad Sci Inst Math HANS Zhengzhou 450046 Peoples R China

Agile-satellite mission planning is a crucial issue in the construction of satellite constellations. The large scale of remote sensing missions and the high complexity of constraints in agile-satellite mission planning pose challenges in the search for an optimal solution. To tackle the issue, a dynamic destroy deep-reinforcement learning (D3RL) model is designed to facilitate subsequent optimization operations via adaptive destruction to the existing solutions. Specifically, we first perform a clustering and embedding operation to reconstruct tasks into a clustering graph, thereby improving data utilization. Secondly, the D3RL model is established based on graph attention networks (GATs) to enhance the search efficiency for optimal solutions. Moreover, we present two applications of the D3RL model for intensive scenes: the deep-reinforcement learning (DRL) method and the D3RL-based large-neighborhood search method (DRL-LNS). Experimental simulation results illustrate that the D3RL-based approaches outperform the competition in terms of solutions' quality and computational efficiency, particularly in more challenging large-scale scenarios. DRL-LNS outperforms ALNS with an average scheduling rate improvement of approximately 11% in Area instances. In contrast, the DRL approach performs better in World scenarios, with an average scheduling rate that is around 8% higher than that of ALNS.

关键词： agile-satellite mission planning graph attention network deep-reinforcement learning large-neighborhood search dynamic destroy

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